76 results on '"Tolan, Dean R"'
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2. Mode of substrate binding for ketohexokinase across isozymes and species implies an induced-fit mechanism
3. Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase
4. Could Alzheimer’s disease be a maladaptation of an evolutionary survival pathway mediated by intracerebral fructose and uric acid metabolism?
5. Fructose: A New Variable to Consider in SIADH and the Hyponatremia Associated With Long-Distance Running?
6. Uric Acid as a Cause of the Metabolic Syndrome
7. Buildout and integration of an automated high-throughput CLIA laboratory for SARS-CoV-2 testing on a large urban campus
8. Gluconeogenesis
9. Detailed Overview of the Buildout and Integration of an Automated High-Throughput CLIA Laboratory for SARS-CoV-2 Testing on a Large Urban Campus
10. Protein-Metabolite Interactomics Reveals Novel Regulation of Carbohydrate Metabolism
11. The role of thrifty genes in the origin of alcoholism: A narrative review and hypothesis
12. Actin filament‐ and Wiskott‐Aldrich syndrome protein‐binding sites on fructose‐1,6‐bisphosphate aldolase are functionally distinct from the active site
13. Hyperuricemia in Kidney Disease: A Major Risk Factor for Cardiovascular Events, Vascular Calcification, and Renal Damage
14. Cerebral Fructose Metabolism as a Potential Mechanism Driving Alzheimer’s Disease
15. Fructose contributes to the Warburg effect for cancer growth
16. Fructose Production and Metabolism in the Kidney
17. Recent advances in the pathogenesis of hereditary fructose intolerance: implications for its treatment and the understanding of fructose-induced non-alcoholic fatty liver disease
18. Increase of core temperature affected the progression of kidney injury by repeated heat stress exposure
19. Climate Change and the Kidney
20. Fructose and sugar: A major mediator of non-alcoholic fatty liver disease
21. Ketohexokinase C blockade ameliorates fructose-induced metabolic dysfunction in fructose-sensitive mice
22. Role of fructose and fructokinase in acute dehydration-induced vasopressin gene expression and secretion in mice
23. Specific regions of the brain are capable of fructose metabolism
24. Phosphoinositide 3-Kinase Regulates Glycolysis through Mobilization of Aldolase from the Actin Cytoskeleton
25. Enzyme Substrate Specificity Conferred by Distinct Conformational Pathways
26. Aldolase-B knockout in mice phenocopies hereditary fructose intolerance in humans
27. Phosphoinositide 3-Kinase regulates glycolysis through mobilization of Aldolase A from the actin cytoskeleton
28. Aldolase sequesters WASP and affects WASP/Arp2/3‐stimulated actin dynamics
29. Targeting of Several Glycolytic Enzymes Using RNA Interference Reveals Aldolase Affects Cancer Cell Proliferation through a Non-glycolytic Mechanism
30. Stabilization of the Predominant Disease-Causing Aldolase Variant (A149P) with Zwitterionic Osmolytes
31. Mutations in the promoter region of the aldolase B gene that cause hereditary fructose intolerance
32. Increased prevalence of mutant null alleles that cause hereditary fructose intolerance in the American population
33. Chemical-modification rescue assessed by mass spectrometry demonstrates that γ-thia-lysine yields the same activity as lysine in aldolase
34. Structure of human brain fructose 1,6-(bis)phosphate aldolase: Linking isozyme structure with function
35. Structure of a rabbit muscle fructose-1,6-bisphosphate aldolase A dimer variant
36. Thermodynamic Analysis Shows Conformational Coupling and Dynamics Confer Substrate Specificity in Fructose-1,6-bisphosphate Aldolase
37. Fructose metabolism in the cerebellum
38. New Superfamily Members Identified for Schiff-Base Enzymes Based on Verification of Catalytically Essential Residues
39. Genes required for fructose metabolism are expressed in Purkinje cells in the cerebellum
40. Aminoethylation in model peptides reveals conditions for maximizing thiol specificity
41. Structure of the Thermolabile Mutant Aldolase B, A149P: Molecular Basis of Hereditary Fructose Intolerance
42. Hemolytic anemia and severe rhabdomyolysis caused by compound heterozygous mutations of the gene for erythrocyte/muscle isozyme of aldolase, ALDOA(Arg303X/Cys338Tyr)
43. Presteady-State Kinetic Evidence for a Ring-Opening Activity in Fructose-1,6-(bis)phosphate Aldolase
44. A Six-month-old infant with liver steatosis
45. Intein-mediated purification of a recombinantly expressed peptide
46. Fructo-oligosaccharide tolerance in patients with hereditary fructose intolerance. A preliminary nonrandomized open challenge short-term study
47. Spatial Clustering of Isozyme-specific Residues Reveals Unlikely Determinants of Isozyme Specificity in Fructose-1,6-bisphosphate Aldolase
48. The temperature dependence of activity and structure for the most prevalent mutant aldolase B associated with hereditary fructose intolerance
49. Intraneuronal Aβ42 accumulation in Down syndrome brain
50. Snapshots of Catalysis: the Structure of Fructose-1,6-(bis)phosphate Aldolase Covalently Bound to the Substrate Dihydroxyacetone Phosphate,
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