97 results on '"Stone, Laura S."'
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2. Differential Deoxyribonucleic Acid Methylation in Painful Versus Non-Painful Degenerating Intervertebral Discs: A Human Case Study
3. Intervertebral disc human nucleus pulposus cells associated with back pain trigger neurite outgrowth in vitro and pain behaviors in rats
4. The Understanding persistent Pain Where it ResiDes study of low back pain cohort profile
5. Adverse childhood experience is associated with an increased risk of reporting chronic pain in adulthood: a stystematic review and meta-analysis
6. Genome wide association joint analysis reveals 99 risk loci for pain susceptibility and pleiotropic relationships with psychiatric, metabolic, and immunological traits
7. Stiffness and axial pain are associated with the progression of calcification in a mouse model of diffuse idiopathic skeletal hyperostosis
8. Environmentally stressed human nucleus pulposus cells trigger the onset of discogenic low back pain
9. Macrophages and Intervertebral Disc Degeneration
10. Sex-specific effects of neuropathic pain on long-term pain behavior and mortality in mice
11. TAK-242 treatment and its effect on mechanical properties and gene expression associated with IVD degeneration in SPARC-null mice
12. The Canadian version of the National Institutes of Health minimum dataset for chronic low back pain research: reference values from the Quebec Low Back Pain Study
13. DNA Methylation in Degenerating Human Intervertebral Discs
14. The Role of Surface Chemistry in the Osseointegration of PEEK Implants
15. Low back pain definitions: effect on patient inclusion and clinical profiles
16. Exercise attenuates low back pain and alters epigenetic regulation in intervertebral discs in a mouse model
17. Epigenetic signature of chronic low back pain in human T cells
18. Disc degeneration spreads: long-term behavioural, histologic and radiologic consequences of a single-level disc injury in active and sedentary mice
19. Multifidus Muscle Fiber Type Distribution is Changed in Mouse Models of Chronic Intervertebral Disc Degeneration, but is not Attenuated by Whole Body Physical Activity
20. Effect of voluntary running activity on mRNA expression of extracellular matrix genes in a mouse model of intervertebral disc degeneration
21. Diet-induced obesity leads to behavioral indicators of pain preceding structural joint damage in wild-type mice
22. Mechanical Consequence of Induced Intervertebral Disc Degeneration in the SPARC-Null Mouse
23. Adverse childhood experience and adult persistent pain and disability: protocol for a systematic review and meta-analysis
24. Diet-induced Obesity Leads to Behavioral Indicators of Pain Preceding Structural Joint Damage in Wild-Type Mice.
25. Optimization of a rat lumbar IVD degeneration model for low back pain
26. The transition from acute to chronic pain: dynamic epigenetic reprogramming of the mouse prefrontal cortex up to 1 year after nerve injury
27. Hypoxic stress enhances extension and branching of dorsal root ganglion neuronal outgrowth
28. The geriatric pain experience in mice: intact cutaneous thresholds but altered responses to tonic and chronic pain
29. TACAN Is an Ion Channel Involved in Sensing Mechanical Pain
30. Prenatal maternal stress is associated with increased sensitivity to neuropathic pain and sex-specific changes in supraspinal mRNA expression of epigenetic- and stress-related genes in adulthood
31. Long‐term histological analysis of innervation and macrophage infiltration in a mouse model of intervertebral disc injury–induced low back pain
32. Diverse Role of Biological Plasticity in Low Back Pain and Its Impact on Sensorimotor Control of the Spine
33. Interleukin-8 as a therapeutic target for chronic low back pain: Upregulation in human cerebrospinal fluid and pre-clinical validation with chronic reparixin in the SPARC-null mouse model
34. Epigenetics and chronic pain
35. The antidepressant drug, sertraline, hinders bone healing and osseointegration in rats’ tibiae
36. Dysregulation of the Inflammatory Mediators in the Multifidus Muscle After Spontaneous Intervertebral Disc Degeneration SPARC-null Mice is Ameliorated by Physical Activity
37. Low back pain and disc degeneration are decreased following chronic toll-like receptor 4 inhibition in a mouse model
38. Alternative Splicing of the Delta-Opioid Receptor Gene Suggests Existence of New Functional Isoforms
39. Chronic neuropathic pain reduces opioid receptor availability with associated anhedonia in rat
40. Delayed onset of persistent discogenic axial and radiating pain after a single-level lumbar intervertebral disc injury in mice
41. Anti–nerve growth factor therapy attenuates cutaneous hypersensitivity and musculoskeletal discomfort in mice with osteoporosis
42. Evidence for a Role of Nerve Injury in Painful Intervertebral Disc Degeneration: A Cross-Sectional Proteomic Analysis of Human Cerebrospinal Fluid
43. Intervertebral disc degeneration and low back pain: Pre‐clinical studies and clinical implications
44. Preoperative Distress Factors Predicting Postoperative Pain in Adolescents Undergoing Surgery: A Preliminary Study
45. Chronic Osteoporotic Pain in Mice: Cutaneous and Deep Musculoskeletal Pain Are Partially Independent of Bone Resorption and Differentially Sensitive to Pharmacological Interventions
46. Therapeutic benefits of the methyl donor S-adenosylmethionine on nerve injury–induced mechanical hypersensitivity and cognitive impairment in mice
47. Toll-like Receptor 2 Regulates Nerve Growth Factor Synthesis via NF-κB Signaling in Human Intervertebral Disc Cells
48. Nerve Growth Factor Is Regulated by Toll-Like Receptor 2 in Human Intervertebral Discs
49. Overlapping signatures of chronic pain in the DNA methylation landscape of prefrontal cortex and peripheral T cells
50. Structural and functional interactions between six-transmembrane μ-opioid receptors and β2-adrenoreceptors modulate opioid signaling
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