39 results on '"Spencer, Robert H"'
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2. A phase 2 study of oral difelikefalin in subjects with chronic kidney disease and moderate-to-severe pruritus
3. Assessment of the physical dependence potential of difelikefalin: Randomized placebo‐controlled study in patients receiving hemodialysis
4. Psychometric validation and meaningful change thresholds of the Worst Itching Intensity Numerical Rating Scale for assessing itch in patients with chronic kidney disease-associated pruritus
5. Evaluation of the abuse potential of difelikefalin, a selective kappa‐opioid receptor agonist, in recreational polydrug users
6. Clinically meaningful change in itch intensity scores: An evaluation in patients with chronic kidney disease–associated pruritus
7. Randomized Controlled Trial of Difelikefalin for Chronic Pruritus in Hemodialysis Patients
8. Investigation of the κ-opioid receptor agonist cr845 and reference comparator, butorphanol, in rats trained to discriminate (−)pentazocine from saline
9. Discovery of MK-1832, a Kv1.5 inhibitor with improved selectivity and pharmacokinetics
10. Subjective and objective evidence of low abuse potential of the peripherally-acting kappa opioid, CR845, compared with pentazocine
11. Poster 147 CR845, a Peripheral Kappa Opioid Receptor Agonist, Provides Better Pain Relief With Less Nausea and Vomiting Than Placebo in Patients After Bunionectomy
12. Poster 146 CR845, a Novel Peripherally-Acting Kappa Opioid Receptor Agonist, Has Low Abuse Potential Compared With Pentazocine
13. Identification of non-amidine inhibitors of acid-sensing ion channel-3 (ASIC3)
14. Reversal of acid-induced and inflammatory pain by the selective ASIC3 inhibitor, APETx2
15. Discovery of triarylethanolamine inhibitors of the Kv1.5 potassium channel
16. Synthesis, Structure−Activity Relationship, and Pharmacological Profile of Analogs of The ASIC-3 Inhibitor A-317567
17. Amidine derived inhibitors of acid-sensing ion channel-3 (ASIC3)
18. Amiloride derived inhibitors of acid-sensing ion channel-3 (ASIC3)
19. Analogs of MK-499 are differentially affected by a mutation in the S6 domain of the hERG K+ channel
20. Peripheral mechanisms of pain and analgesia
21. High-throughput analysis of drug binding interactions for the human cardiac channel, Kv1.5
22. Ion Channel Structural Studies
23. Integration of Postclosure Safety Analysis with Repository Design for the Yucca Mountain Repository through the Selection of Design Control Parameters
24. Expression, purification and crystallization of human 5-lipoxygenase-activating protein with leukotriene-biosynthesis inhibitors
25. Crystal Structure of Inhibitor-Bound Human 5-Lipoxygenase-Activating Protein
26. Potent antagonists of the Kv1.5 potassium channel: Synthesis and evaluation of analogous N,N-diisopropyl-2-(pyridine-3-yl)acetamides
27. Design and Synthesis of Novel Isoquinoline-3-nitriles as Orally Bioavailable Kv1.5 Antagonists for the Treatment of Atrial Fibrillation
28. Approaches for Ion Channel Structural Studies
29. TBX5 Genetic Testing Validates Strict Clinical Criteria for Holt-Oram Syndrome
30. High Throughput Assay Technologies for Ion Channel Drug Discovery
31. The α-Helix and the Organization and Gating of Channels
32. Monte Carlo modeling of radiation dose distributions in intravascular radiation therapy
33. Crystallographic Analyses of Ion Channels: Lessons and Challenges
34. Erratum: ‘Feeling the pressure’: structural insights into a gated mechanosensitive channel
35. Structure of the MscL Homolog from Mycobacterium tuberculosis : A Gated Mechanosensitive Ion Channel
36. Purification, Visualization, and Biophysical Characterization of Kv1.3 Tetramers
37. Noise Control of the Standard Light Rail Vehicle
38. Operational Aspects of Helicopter Noise
39. Recent Research in Rotor-Noise Reduction
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