18 results on '"Snoeys J"'
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2. Intestinal organoids as in vitro model system to assess safety and ADME properties of compounds
3. HUB Organoids™ improve pre-clinical toxicology, metabolism, and pharmacokinetic studies for drug discovery and development
4. Ibrutinib Dosing Strategies Based on Interaction Potential of CYP3A4 Perpetrators Using Physiologically Based Pharmacokinetic Modeling
5. In Vitro and In Vivo Drug-Drug Interaction Studies to Assess the Effect of Abiraterone Acetate, Abiraterone, and Metabolites of Abiraterone on CYP2C8 Activity
6. Preclinical Characterisation of JNJ-54257099 – A Potent Uridine-Based Nucleotide Polymerase Inhibitor in Phase I Clinical Development for the Treatment of Chronic Hepatitis C
7. Mechanistic understanding of the nonlinear pharmacokinetics and intersubject variability of simeprevir: A PBPK-guided drug development approach
8. Physiologically based pharmacokinetic modeling in drug discovery and development: A pharmaceutical industry perspective
9. Evaluation of Various Static In Vitro–In Vivo Extrapolation Models for Risk Assessment of the CYP3A Inhibition Potential of an Investigational Drug
10. Explosion Protection with Metal Dust Fuels: New Experimental Evidence
11. The impact of antigen expression in antigen-presenting cells on humoral immune responses against the transgene product
12. Apolipoprotein A-I and lecithin:cholesterol acyltransferase transfer induce cholesterol unloading in complex atherosclerotic lesions
13. Direct comparison of hepatocyte-specific expression cassettes following adenoviral and nonviral hydrodynamic gene transfer
14. Species differences in transgene DNA uptake in hepatocytes after adenoviral transfer correlate with the size of endothelial fenestrae
15. ID: 22 Overexpression of TIMP-1 in mice does not affect adipogenesis or adipose tissue development
16. Th-W61:8 Human apo A-1 transfer enhances expansive remodeling and intimal angiogenesis in a murine model of transplant vasculopathy
17. Mo-P3:218 ATP-binding cassette transporter A1 gene transfer increases HDL cholesterol but accelerates progression of atherosclerosis in APO E-/- mice
18. The size of sinusoidal fenestrae is a critical determinant of hepatocyte transduction after adenoviral gene transfer
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