176 results on '"Sauna A"'
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2. Application of Machine Learning Approaches for Predicting Hemophilia A Severity
3. Factor VIII moiety of recombinant Factor VIII Fc fusion protein impacts Fc effector function and CD16+ NK cell activation
4. Proceedings of the 14th European immunogenicity platform open symposium on immunogenicity of biopharmaceuticals
5. Dose optimization of an adjuvanted peptide-based personalized neoantigen melanoma vaccine
6. The MHC Associated Peptide Proteomics assay is a useful tool for the non-clinical assessment of immunogenicity
7. OC 04.5 Structural, Functional, and Immunogenicity Implications of F9 Gene Recoding
8. PB1316 Impact of Synonymous Gene Recoding on ADAMTS13
9. OC 31.4 Novel Factor Xa agents that Restore Hemostasis in Mice Treated with Apixaban
10. PB1051 Tyrosine Under-Sulfation of Factor VIII Results in T-Cell Response and Decreased Affinity Towards Thrombin in a Model System
11. Emerging approaches to induce immune tolerance to therapeutic proteins
12. Understanding preclinical and clinical immunogenicity risks in novel biotherapeutics development
13. Fusion partners matter: Factor VIII light chain binding enables CD16-mediated recombinant Factor VIII-Fc fusion protein natural killer cell activation.
14. Archaeal and bacteriophage derived Cas proteins demonstrate memory T cell response in humans
15. Artificial Intelligence (AI) based approach for identifying biomarkers associated with neutralizing antidrug antibodies to Factor VIII used in Hemophilia A treatment
16. A machine learning approach for identifying variables associated with risk of developing neutralizing antidrug antibodies to factor VIII
17. Pharmacokinetics of antibodies during pregnancy: General pharmacokinetics and pregnancy related physiological changes (Part 1)
18. Computational design of nanomolar-binding antibodies specific to multiple SARS-CoV-2 variants by engineering a specificity switch of antibody 80R using RosettaAntibodyDesign (RAbD) results in potential generalizable therapeutic antibodies for novel SARS-CoV-2 virus
19. Pengaruh Efikasi Diri dan Pendidikan Kewirausahaan Terhadap Minat Berwirausaha Yang Dimediasi oleh Motivasi Berwirausaha pada Mahasiswa Universitas Jambi (Studi Kasus Mahasiswa Pendidikan Ekonomi)
20. A Retrospective Review of Center for Biologics Evaluation and Research Advisory Committee Meetings in the Context of the FDA’s Benefit-Risk Framework
21. Pharmacokinetics of antibodies during Pregnancy: Impact of pregnancy on the pharmacokinetics of antibodies (Part 2)
22. Modeling and Simulation of CAR T cell Therapy in Chronic Lymphocytic Leukemia Patients
23. Structural, functional, and immunogenicity implications of F9 gene recoding
24. A structural homology approach to identify potential cross-reactive antibody responses following SARS-CoV-2 infection
25. Actividad antibacteriana de Myrcianthes myrsinoides y Clinopodium pulchellum procedentes del cerro “La Botica” región La Libertad
26. Fortalecimiento de las lenguas indígenas en Colombia
27. Summary of a Public FDA Workshop: Model Informed Drug Development Approaches for Immunogenicity Assessments
28. Endotoxin contamination in commercially available Cas9 proteins potentially induces T-cell mediated responses
29. Secondary failure: immune responses to approved protein therapeutics
30. Mathematical model of a personalized neoantigen cancer vaccine and the human immune system
31. AptaCluster – A Method to Cluster HT-SELEX Aptamer Pools and Lessons from Its Application
32. Cas9-derived peptides presented by MHC Class II that elicit proliferation of CD4+ T-cells
33. Neurocognitive follow‐up in adult siblings with Phelan–McDermid syndrome due to a novel SHANK3 splicing site mutation
34. Factor VIII-Fc Activates Natural Killer Cells via Fc-Mediated Interactions With CD16
35. TBC1D24 and Its Related Epileptic Encephalopathy
36. HLA Variants and Inhibitor Development in Hemophilia A: A Retrospective Case-Controlled Study Using the ATHNdataset
37. Factor VIII-Fc activates natural killer cells via Fc-mediated interactions with CD16
38. MECP2-Related Disorders and Epilepsy Phenotypes
39. Higher-Order Structure and Protein Aggregate Characterization of Protein Therapeutics: Perspectives from Good Manufacturing Practices and Regulatory Guidance
40. Mathematical Model of a Personalized Neoantigen Cancer Vaccine and the Human Immune System: Evaluation of Efficacy
41. Silent (Synonymous) SNPs: Should We Care About Them?
42. Editorial: Immunogenicity of Proteins Used as Therapeutics
43. Modified aptamers as reagents to characterize recombinant human erythropoietin products
44. Efficient Propagation of Circulating Tumor Cells: A First Step for Probing Tumor Metastasis
45. A Foundational Study for Normal F8-Containing Mouse Models for the miRNA Regulation of Hemophilia A: Identification and Analysis of Mouse miRNAs that Downregulate the Murine F8 Gene
46. Further Evidence That MicroRNAs Can Play a Role in Hemophilia A Disease Manifestation: F8 Gene Downregulation by miR-19b-3p and miR-186-5p
47. Role of microRNAs in Hemophilia and Thrombosis in Humans
48. Ageing and cognition in men with fragile X syndrome
49. Quantitative HLA‐class‐II/factor VIII (FVIII) peptidomic variation in dendritic cells correlates with the immunogenic potential of therapeutic FVIII proteins in hemophilia A
50. SampPick: Selection of a Cohort of Subjects Matching a Population HLA Distribution
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