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1. Epigenetic and proteomic signatures associate with clonal hematopoiesis expansion rate

2. Determinants of mosaic chromosomal alteration fitness

3. Large language models facilitate the generation of electronic health record phenotyping algorithms

5. Interoperability of phenome-wide multimorbidity patterns: a comparative study of two large-scale EHR systems

7. Recurrence After Atrial Fibrillation Ablation and Investigational Biomarkers of Cardiac Remodeling

9. Multifocal Ectopic Purkinje Premature Contractions due to neutralization of an SCN5A negative charge: structural insights into the gating pore hypothesis

10. Unbiased characterization of atrial fibrillation phenotypic architecture provides insight to genetic liability and clinically relevant outcomes

11. Prognostic Value of Multiplexed Assays of Variant Effect and Automated Patch-clamping forKCNH2-LQTS Risk Stratification

12. Antipsychotics and the QTc Interval During Delirium in the Intensive Care Unit

13. The impact of damaging epilepsy and cardiac genetic variant burden in sudden death in the young

14. Multi-site validation of a functional assay to adjudicate SCN5A Brugada Syndrome-associated variants

15. Genomic medicine year in review: 2023

18. Abstract 15689: Ablation for Atrial Fibrillation in Patients With Rare Pathogenic Variants in Cardiomyopathy and Arrhythmia Genes

20. Next-generation phenotyping: introducing phecodeX for enhanced discovery research in medical phenomics

22. Determinants of mosaic chromosomal alteration fitness

23. Proteomic and genetic analyses of influenza A viruses identify pan-viral host targets

25. Demonstrating paths for unlocking the value of cloud genomics through cross cohort analysis

26. Clinical consequences of a polygenic predisposition to benign lower white blood cell counts

27. The All of Us Data and Research Center: Creating a Secure, Scalable, and Sustainable Ecosystem for Biomedical Research

28. PheMIME: An Interactive Web App and Knowledge Base for Phenome-Wide, Multi-Institutional Multimorbidity Analysis

29. Leveraging Generative AI to Prioritize Drug Repurposing Candidates: Validating Identified Candidates for Alzheimer’s Disease in Real-World Clinical Datasets

30. Pulmonary Vein Myocardial Sleeve Length and its Association With Sex and 4q25/PITX2 Genotype

31. Laboratory and demographic predictors of functional assay positive status in suspected heparin-induced thrombocytopenia: A multicenter retrospective cohort study

33. EN-452414-5 VENTRICULAR CONDUCTION IS A MARKER FOR ARRHYTHMIC RISK IN OVERLAP SODIUM CHANNEL DISEASE

36. Multicenter Clinical and Functional Evidence Reclassifies a Recurrent Non-canonical Filamin C Splice-altering Variant

37. PO-04-195 NOT JUST FOR THE YOUNG: GENETIC TESTING IN OLDER PATIENTS WITH NONISCHEMIC CARDIOMYOPATHY AND VENTRICULAR TACHYCARDIA

40. High-throughput functional mapping of variants in an arrhythmia gene,KCNE1, reveals novel biology

41. Detection of distant familial relatedness in biobanks for identification of undiagnosed carriers of a Mendelian disease variant: application to Long QT Syndrome

42. Author Correction: Association of step counts over time with the risk of chronic disease in the All of Us Research Program

43. Returning integrated genomic risk and clinical recommendations: The eMERGE study

46. Contributors

47. List of Contributors

48. The impact of damaging epilepsy and cardiac genetic variant burden in sudden death in the young

50. Transcriptional Dysregulation Underlies Both Monogenic Arrhythmia Syndrome and Common Modifiers of Cardiac Repolarization

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