70 results on '"Rahmani, Roger"'
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2. The Anti-Cancer Drug Dabrafenib Is a Potent Activator of the Human Pregnane X Receptor
3. An adverse outcome pathway-based approach to assess steatotic mixture effects of hepatotoxic pesticides in vitro
4. Adverse Outcome Pathway-Driven Analysis of Liver Steatosis in Vitro: A Case Study with Cyproconazole
5. An accurate and robust LC-MS/MS method for the quantification of chlorfenvinphos, ethion and linuron in liver samples
6. Evidence of in vitro metabolic interaction effects of a chlorfenvinphos, ethion and linuron mixture on human hepatic detoxification rates
7. Antioxidant properties of tea blunt ROS-dependent lipogenesis: beneficial effect on hepatic steatosis in a high fat-high sucrose diet NAFLD obese rat model
8. Trans-nonachlor decreases miR-141-3p levels in human melanocytes in vitro promoting melanoma cell characteristics and shows a multigenerational impact on miR-8 levels in Drosophila
9. 0149 : Antioxidant molecules of tea (Camellia sinensis) decrease hepatic lipogenesis and steatosis in a high fat-sucrose diet NAFLD rat model
10. Prediction of the metabolic clearance of benzophenone-2, and its interaction with isoeugenol and coumarin using cryopreserved human hepatocytes in primary culture
11. High-content screening imaging and real-time cellular impedance monitoring for the assessment of chemical’s bio-activation with regards hepatotoxicity
12. Synergistic activation of human pregnane X receptor by binary cocktails of pharmaceutical and environmental compounds
13. Effect of Brewing Duration on the Antioxidant and Hepatoprotective Abilities of Tea Phenolic and Alkaloid Compounds in a t-BHP Oxidative Stress-Induced Rat Hepatocyte Model
14. 0217 : Antioxidant and protective effects of a pu-erh tea extract (camellia sinensis) on primary cultured rat cells
15. Potential involvement of chemicals in liver cancer progression: An alternative toxicological approach combining biomarkers and innovative technologies
16. Is bisphenol S a safe substitute for bisphenol A in terms of metabolic function? An in vitro study
17. A Concentration Addition Model to Assess Activation of the Pregnane X Receptor (PXR) by Pesticide Mixtures Found in the French Diet
18. In vitro metabolism of permethrin and two metabolites by human primary hepatocytes
19. Comparative study of bisphenol A and its analogue bisphenol S on human hepatic cells: A focus on their potential involvement in nonalcoholic fatty liver disease
20. 0261 Hao Ling pu-erh tea attenuates lipid accumulation in primary culture rat hepatocytes
21. Atrazine represses S100A4 gene expression and TPA-induced motility in HepG2 cells
22. Cellular impact of combinations of endosulfan, atrazine, and chlorpyrifos on human primary hepatocytes and HepaRG cells after short and chronic exposures
23. Crosstalk between Beta-Catenin and Snail in the Induction of Epithelial to Mesenchymal Transition in Hepatocarcinoma: Role of the ERK1/2 Pathway
24. Organochlorine pesticides induce epithelial to mesenchymal transition of human primary cultured hepatocytes
25. Effects of endosulfan on hepatoma cell adhesion: Epithelial–mesenchymal transition and anoikis resistance
26. Impacts of low doses of pesticide mixtures on liver cell defence systems
27. Development of a liquid chromatography/atmospheric pressure photo-ionization high-resolution mass spectrometry analytical method for the simultaneous determination of polybrominated diphenyl ethers and their metabolites: application to BDE-47 metabolism i
28. Molecular investigation of the effects of lindane in rat hepatocytes: Microarray and mechanistic studies
29. Anti-Apoptotic Pro-Survival Effect of Clotrimazole in a Normothermic Ischemia Reperfusion Injury Animal Model
30. Bis(hydroxyphenyl)methane—bisphenol F—metabolism by the HepG2 human hepatoma cell line and cryopreserved human hepatocytes
31. Pregnane X receptor activation protects rat hepatocytes against deoxycholic acid-induced apoptosis
32. Lindane and cell death: At the crossroads between apoptosis, necrosis and autophagy
33. Comparison of genistein metabolism in rats and humans using liver microsomes and hepatocytes
34. Endosulfan decreases cell growth and apoptosis in human HaCaT keratinocytes: Partial ROS-dependent ERK1/2 mechanism
35. Activation of α- and β-estrogen receptors by persistent pesticides in reporter cell lines
36. Regulation of Bcl-2 and Bcl-xL anti-apoptotic protein expression by nuclear receptor PXR in primary cultures of human and rat hepatocytes
37. Effects of Organochlorine Insecticides on MAP Kinase Pathways in Human HaCaT Keratinocytes: Key Role of Reactive Oxygen Species
38. Activation of retinoic acid receptor-dependent transcription by organochlorine pesticides
39. A PXR reporter gene assay in a stable cell culture system: CYP3A4 and CYP2B6 induction by pesticides
40. In vivo distribution and metabolisation of14C-imidacloprid in different compartments ofApis mellifera L
41. Effect of organochlorine pesticides on human androgen receptor activation in vitro
42. Microcystin-LR causes the collapse of actin filaments in primary human hepatocytes
43. Spot 14 protein interacts and co-operates with chicken ovalbumin upstream promoter-transcription factor 1 in the transcription of the L-type pyruvate kinase gene through a specificity protein 1 (Sp1) binding site
44. Spot 14 protein interacts and co-operates with chicken ovalbumin upstream promoter-transcription factor 1 in the transcription of the L-type pyruvate kinase gene through a specificity protein 1 (Sp1) binding site
45. Induction of cytochrome P450 1A1 gene expression, oxidative stress, and genotoxicity by carbaryl and thiabendazole in transfected human HepG2 and lymphoblastoid cells22Abbreviations: AhR, aryl hydrocarbon receptor; CAT, chloramphenicol acetyl transferase; CYP1A1, cytochrome P450 1A1; FBS, fetal bovine serum; GADD, growth arrest and DNA damage; GRP78, 78-kD glucose-regulated protein; GST, glutathione S-transferase; HMTII, human metallothionein II; HSP, heat shock protein; 3-MC, 3-methylcholanthrene; NF-κBRE, nuclear factor of κ enhancer responsive element; RARE, retinoid acid responsive element; TCDD, 2,3,7,8-tetrachlorodibenzo-p-dioxin; TCDF, 2,3,7,8-tetrachlorodibenzofuran; UDS, unscheduled DNA synthesis; and XRE, xenobiotic responsive element.
46. Effects of heavy metals and 3‐methylcholanthrene on expression and induction of CYP1A1 and metallothionein levels in trout (Oncorhynchus mykiss) hepatocyte cultures
47. EFFECTS OF HEAVY METALS AND 3-METHYLCHOLANTHRENE ON EXPRESSION AND INDUCTION OF CYP1A1 AND METALLOTHIONEIN LEVELS IN TROUT (ONCORHYNCHUS MYKISS) HEPATOCYTE CULTURES
48. Present status of the application of cryopreserved hepatocytes in the evaluation of xenobiotics: consensus of an international expert panel
49. Comparative effects of rifabutin and rifampicin on cytochromes P450 and UDP-glucuronosyl-transferases expression in fresh and cryopreserved human hepatocytes
50. A multi-laboratory evaluation of cryopreserved monkey hepatocyte functions for use in pharmaco–toxicology
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