61 results on '"Miranda, Les P."'
Search Results
2. Development of human-machine language interfaces for the visual analysis of complex biologics and RNA modalities and associated experimental data
3. Metal-Free Polymer-Based Affinity Medium for Selective Purification of His6-Tagged Proteins
4. Discovery of Selective Pituitary Adenylate Cyclase 1 Receptor (PAC1R) Antagonist Peptides Potent in a Maxadilan/PACAP38-Induced Increase in Blood Flow Pharmacodynamic Model
5. Solid-Phase Peptide Synthesis Using Microwave Irradiation
6. Half-life extension of peptidic APJ agonists by N-terminal lipid conjugation
7. Use of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical Species
8. Cover Image, Volume 116, Number 9, September 2019
9. Structure-guided discovery of dual recognition chemibodies
10. Nanoscale integration of single cell biologics discovery processes using optofluidic manipulation and monitoring
11. Engineering NaV1.7 Inhibitory JzTx-V Peptides with a Potency and Basicity Profile Suitable for Antibody Conjugation To Enhance Pharmacokinetics
12. Peptide-Membrane Interactions Affect the Inhibitory Potency and Selectivity of Spider Toxins ProTx-II and GpTx-1
13. Discovery of Tarantula Venom-Derived NaV1.7-Inhibitory JzTx-V Peptide 5-Br-Trp24 Analogue AM-6120 with Systemic Block of Histamine-Induced Pruritis
14. Structure-guided Discovery of Dual-recognition Chemibodies
15. Pharmacological characterization of potent and selective NaV1.7 inhibitors engineered from Chilobrachys jingzhao tarantula venom peptide JzTx-V
16. Identification of Antibody and Small Molecule Antagonists of Ferroportin-Hepcidin Interaction
17. Engineering Antibody Reactivity for Efficient Derivatization to Generate NaV1.7 Inhibitory GpTx-1 Peptide–Antibody Conjugates
18. Progress and challenges in the optimization of toxin peptides for development as pain therapeutics
19. Single Residue Substitutions That Confer Voltage-Gated Sodium Ion Channel Subtype Selectivity in the NaV1.7 Inhibitory Peptide GpTx-1
20. A Potent d-Protein Antagonist of VEGF-A is Nonimmunogenic, Metabolically Stable, and Longer-Circulating in Vivo
21. Sustained inhibition of the Na V 1.7 sodium channel by engineered dimers of the domain II binding peptide GpTx-1
22. Pharmaceutical Optimization of Peptide Toxins for Ion Channel Targets: Potent, Selective, and Long-Lived Antagonists of Kv1.3
23. Engineering Potent and Selective Analogues of GpTx-1, a Tarantula Venom Peptide Antagonist of the NaV1.7 Sodium Channel
24. Synthesis of small cyclic peptides: An auxiliary approach to address the “difficult cyclization” problem
25. Epitope Discovery for a Synthetic Polymer Nanoparticle: A New Strategy for Developing a Peptide Tag
26. Peptide antagonists of the calcitonin gene-related peptide (CGRP) receptor with improved pharmacokinetics and pharmacodynamics
27. ChemInform Abstract: Solid-Phase Peptide Synthesis Using Microwave Irradiation
28. Molecular Mechanism of Hepcidin-Mediated Ferroportin Internalization Requires Ferroportin Lysines, Not Tyrosines or JAK-STAT
29. Utilization of tyrosine‐ and histidine‐containing dipeptides to enhance productivity and culture viability
30. Direct Quantitative Analysis of a 20 kDa PEGylated Human Calcitonin Gene Peptide Antagonist in Cynomolgus Monkey Serum Using In-Source CID and UPLC-MS/MS
31. Dipeptidyl-Quinolone Derivatives Inhibit Hypoxia Inducible Factor-1α Prolyl Hydroxylases-1, -2, and -3 with Altered Selectivity
32. ChemInform Abstract: Preparation of Novel O-Sulfated Amino Acid Building Blocks with Improved Acid Stability for Fmoc-Based Solid-Phase Peptide Synthesis.
33. Oxidative folding of hepcidin at acidic pH
34. Hepcidin Revisited, Disulfide Connectivity, Dynamics, and Structure
35. Development of a method for the sensitive and quantitative determination of hepcidin in human serum using LC-MS/MS
36. Identification of Potent, Selective, and Metabolically Stable Peptide Antagonists to the Calcitonin Gene-Related Peptide (CGRP) Receptor
37. Design and Synthesis of Conformationally Constrained Glucagon-Like Peptide-1 Derivatives with Increased Plasma Stability and Prolonged in Vivo Activity
38. A Chemical Approach to the Pharmaceutical Optimization of an Anti-HIV Protein
39. Fmoc-Protein Synthesis: Preparation of Peptide Thioesters Using a Side-Chain Anchoring Strategy
40. Site-Specific Polymer Attachment to a CCL-5 (RANTES) Analogue by Oxime Exchange
41. Probing the S100 protein family through genomic and functional analysis
42. A New Approach to the Chemical Synthesis of Keto-Proteins
43. Design and Chemical Synthesis of a Homogeneous Polymer-Modified Erythropoiesis Protein
44. SPOCC-194, a New High Functional Group Density PEG-Based Resin for Solid-Phase Organic Synthesis
45. Preparation of novel O-sulfated amino acid building blocks with improved acid stability for Fmoc-based solid-phase peptide synthesis
46. Cover Picture
47. Titelbild
48. Unichemo Protection: A Concept for Chemical Synthesis This work was supported by the Danish National Research Foundation.
49. Unichemo Protection: A Concept for Chemical Synthesis
50. Solid-Phase Glycosylation of Peptide Templates and On-Bead MAS-NMR Analysis: Perspectives for Glycopeptide Libraries
Catalog
Books, media, physical & digital resources
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.