105 results on '"Micoli, Francesca"'
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2. Development of a visual Adhesion/Invasion Inhibition Assay to assess the functionality of Shigella-specific antibodies
3. Development and Application of a High-Throughput Method for the Purification and Analysis of Surface Carbohydrates from Klebsiella pneumoniae
4. Putative correlates of protection against shigellosis assessing immunomarkers across responses to S. sonnei investigational vaccine
5. Vaccine value profile for Klebsiella pneumoniae
6. Methods for Assessment of OMV/GMMA Quality and Stability
7. O-Antigen decorations in Salmonella enterica play a key role in eliciting functional immune responses against heterologous serovars in animal models
8. Age-dependent acquisition of IgG antibodies to Shigella serotypes—a retrospective analysis of seroprevalence in Kenyan children with implications for infant vaccination
9. Molecular Signature of Monocytes Shaped by the Shigella sonnei 1790-Generalized Modules for Membrane Antigens Vaccine
10. Testing a Recombinant Form of Tetanus Toxoid as a Carrier Protein for Glycoconjugate Vaccines
11. Comparison of Shigella GMMA and glycoconjugate four-component formulations in animals
12. Towards establishing correlates of protection against shigellosis: assessing immunological endpoints across immune responses to the Shigella sonnei Generalized Modules for Membrane Antigens (GMMA) candidate vaccine (1790GAHB).
13. A next-generation GMMA-based vaccine candidate to fight shigellosis
14. O-Antigen Extraction, Purification, and Chemical Conjugation to a Carrier Protein
15. Contributors
16. Glycoconjugate vaccines, production and characterization
17. From an in vivo to an in vitro relative potency (IVRP) assay to fully characterize a multicomponent O-antigen based vaccine against Shigella
18. Elucidating the role of N-acetylglucosamine in Group A Carbohydrate for the development of an effective glycoconjugate vaccine against Group A Streptococcus
19. Exploring the variables influencing the immune response of traditional and innovative glycoconjugate vaccines
20. Functional assays to evaluate antibody-mediated responses against Shigella: a review
21. Efficient Autotransporter-Mediated Extracellular Secretion of a Heterologous Recombinant Protein by Escherichia coli
22. Vi polysaccharide and conjugated vaccines afford similar early, IgM or IgG-independent control of infection but boosting with conjugated Vi vaccines sustains the efficacy of immune responses
23. Toward a Shigella Vaccine: Opportunities and Challenges to Fight an Antimicrobial-Resistant Pathogen
24. Exploring the Role of GMMA Components in the Immunogenicity of a 4-Valent Vaccine against Shigella
25. Strengths and weaknesses of pneumococcal conjugate vaccines
26. Vi polysaccharide and conjugated vaccines afford similar early, IgM or IgG-independent control of infection but boosting with conjugated Vi vaccines sustains the efficacy of immune responses
27. Generalized Modules for Membrane Antigens (GMMA), an outer membrane vesicle‐based vaccine platform, for efficient viral antigen delivery
28. Antigen presentation by Follicular Dendritic cells to cognate B cells is pivotal for Generalised Modules for Membrane Antigens (GMMA) immunogenicity
29. Impact and Control of Sugar Size in Glycoconjugate Vaccines
30. Complement-mediated serum bactericidal activity of antibodies elicited by the Shigella sonnei GMMA vaccine in adults from a shigellosis-endemic country: Exploratory analysis of a Phase 2a randomized study
31. Genetic and Structural Variation in the O-Antigen of Salmonella enterica Serovar Typhimurium Isolates Causing Bloodstream Infections in the Democratic Republic of the Congo
32. Setup and Characterization of a High-Throughput Luminescence-Based Serum Bactericidal Assay (L-SBA) to Determine Functionality of Human Sera against Shigella flexneri
33. Investigating the Role of Antigen Orientation on the Immune Response Elicited by Neisseria meningitidis Factor H Binding Protein on GMMA
34. Rapid generation of Shigella flexneri GMMA displaying natural or new and cross-reactive O-Antigens
35. GMMA as an Alternative Carrier for a Glycoconjugate Vaccine against Group A Streptococcus
36. Towards a Four-Component GMMA-Based Vaccine against Shigella
37. Efficient autotransporter-mediated extracellular secretion of a heterologous recombinant protein by Escherichia coli
38. Dissecting in Vitro the Activation of Human Immune Response Induced by Shigella sonnei GMMA
39. GMMA as a ‘plug and play’ technology to tackle infectious disease to improve global health: context and perspectives for the future
40. Impact of O-Acetylation on S. flexneri 1b and 2a O-Antigen Immunogenicity in Mice
41. Comparison and Optimization of Quantification Methods for Shigella flexneri Serotype 6 O-antigen Containing Galacturonic Acid and Methyl-Pentose
42. Rationalizing the design of a broad coverage Shigella vaccine based on evaluation of immunological cross-reactivity among S. flexneri serotypes
43. Novel Simple Conjugation Chemistries for Decoration of GMMA with Heterologous Antigens
44. Increasing the High Throughput of a Luminescence-Based Serum Bactericidal Assay (L-SBA)
45. Generalized Modules for Membrane Antigens as Carrier for Polysaccharides: Impact of Sugar Length, Density, and Attachment Site on the Immune Response Elicited in Animal Models
46. Efficacy, safety, and immunogenicity of the Shigella sonnei 1790GAHB GMMA candidate vaccine: Results from a phase 2b randomized, placebo-controlled challenge study in adults
47. GMMA-Based Vaccines: The Known and The Unknown
48. Development of a Monocyte Activation Test as an Alternative to the Rabbit Pyrogen Test for Mono- and Multi-Component Shigella GMMA-Based Vaccines
49. Neisseria meningitidis Factor H Binding Protein Surface Exposure on Salmonella Typhimurium GMMA Is Critical to Induce an Effective Immune Response against Both Diseases
50. Antibodies Elicited by the Shigella sonnei GMMA Vaccine in Adults Trigger Complement-Mediated Serum Bactericidal Activity: Results From a Phase 1 Dose Escalation Trial Followed by a Booster Extension
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