70 results on '"Mende, Ulrike"'
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2. Mitochondrial Ca2+uniporter (MCU) variants form plasma-membrane channels
3. Action potential metrics and automated data analysis pipeline for cardiotoxicity testing using optically mapped hiPSC-derived 3D cardiac microtissues
4. Tyrosine phosphorylation of mitofusin 2 regulates endoplasmic reticulum-mitochondria tethering
5. Cardioprotective effects of early intervention with sacubitril/valsartan on pressure overloaded rat hearts
6. α7 Nicotinic acetylcholine receptor mediates right ventricular fibrosis and diastolic dysfunction in pulmonary hypertension
7. A predictive in vitro risk assessment platform for pro-arrhythmic toxicity using human 3D cardiac microtissues
8. A Predictive in Vitro Risk Assessment Platform for Pro-Arrhythmic Toxicity Using Human 3D Cardiac Microtissues
9. Protein phosphorylation in isolated trabeculae from nonfailing and failing human hearts
10. Abstract 186: Superiority of Sacubitril/Valsartan Over Valsartan Alone in Attenuating Pressure Overload-induced Cardiac Fibrosis and Oxidative Stress
11. Directed fusion of cardiac spheroids into larger heterocellular microtissues enables investigation of cardiac action potential propagation via cardiac fibroblasts
12. Proline‐rich Tyrosine Kinase 2 Phosphorylates Mitochondrial Calcium Uniporter and Regulates Mitochondrial Calcium Uptake
13. Cardiac Action Potential Propagation through Compact Fibroblasts in 3D Cardiac Microtissues Engineered from Self-Assembled Spheroids as Building Blocks
14. Protein kinase D activation induces mitochondrial fragmentation and dysfunction in cardiomyocytes
15. In vitromodels of the cardiac microenvironment to study myocyte and non-myocyte crosstalk: bioinspired approaches beyond the polystyrene dish
16. Narrow time window of metabolic changes associated with transition to overt heart failure in Tgaq*44 mice
17. PKD Translocation to the Outer Mitochondrial Membrane Induces Mitochondrial Fragmentation and Cell Death via DLP1 Phosphorylation in Cardiomyocytes
18. Heterotrimeric G protein-mediated signaling and its non-canonical regulation in the heart
19. PKC δ and βII regulate angiotensin II-mediated fibrosis through p38: a mechanism of RV fibrosis in pulmonary hypertension
20. PKD Regulates Mitochondrial Morphology and Function via Phosphorylation of DLP1 in Cardiac Myocytes.
21. Abstract 16606: Cardiac Fibroblast-Restricted Enhancement of G q Signaling Prolongs Calcium Transients and Increases Spontaneous Activity in Biomimetic Cardiac Microtissues
22. Cardiac Overexpression of Constitutively Active Galpha q Causes Angiotensin II Type1 Receptor Activation, Leading to Progressive Heart Failure and Ventricular Arrhythmias in Transgenic Mice
23. Functional role, mechanisms of regulation, and therapeutic potential of regulator of G protein signaling 2 in the heart
24. Abstract 037: Transient Cardiac Expression Of Constitutively Active G alpha Q Activates Renin-angiotensin System, Leading To Progressive Heart Failure And Ventricular Arrhythmias In Transgenic Mice
25. Nicorandil Prevents Gαq-Induced Progressive Heart Failure and Ventricular Arrhythmias in Transgenic Mice
26. Abstract 349: Functional Scaffold-Free 3D Cardiac Microtissues: A Novel Model for the Investigation of Heart Cells
27. Gq/11-Mediated Signaling and Hypertrophy in Mice with Cardiac-Specific Transgenic Expression of Regulator of G-Protein Signaling 2
28. Preserved cardiomyocyte function and altered desmin pattern in transgenic mouse model of dilated cardiomyopathy
29. Abstract P170: Nicorandil Inhibits Gáq-Induced Chronic Heart Failure in Transgenic Mice
30. Regulators of G-Protein Signaling in the Heart and Their Potential as Therapeutic Targets
31. Regulator of G protein signaling 2 is a functionally important negative regulator of angiotensin II-induced cardiac fibroblast responses
32. RGS2 is a primary terminator of β2-adrenergic receptor-mediated Gi signaling
33. Protein Kinase C Isoform Expression Is Altered In Isolated Right Ventricular Cardiomyocytes And Fibroblasts In Pulmonary Arterial Hypertension Secondary To Hypoxia
34. An Improved Isolation Procedure for Adult Mouse Cardiomyocytes
35. Diacylglycerol Kinase ζ Inhibits Ventricular Tachyarrhythmias in a Mouse Model of Heart Failure
36. Effects of Continous Electrical Field Stimulation and Hypertrophic Stimulation on Micropatterned Cardiac Myocytes
37. Generation and characterization of a novel, cardiac‐specific, inducible RGS2 transgenic mouse model to modulate Gq‐mediated cardiac hypertrophy
38. Diacylglycerol kinase ζ inhibits Gαq-induced atrial remodeling in transgenic mice
39. NO and PGI2 in coronary endothelial dysfunction in transgenic mice with dilated cardiomyopathy
40. RGS2 is a negative regulator of Gq/11‐mediated signaling and cell proliferation in adult rat ventricular fibroblasts
41. Enhanced calcium cycling and contractile function in transgenic hearts expressing constitutively active Gαo* protein
42. Diacylglycerol Kinase .ZETA.Rescues G.ALPHA.q-Induced Heart Failure in Transgenic Mice
43. RGS Protein Specificity Towards Gq- and Gi/o-Mediated ERK 1/2 and Akt Activation, in vitro
44. Abstract 559: Diacylglycerol Kinase-ζ Rescues Gαq-induced Heart Failure
45. Kruppel-like factor 15 is a regulator of cardiomyocyte hypertrophy
46. Cardiac myosin missense mutations cause dilated cardiomyopathy in mouse models and depress molecular motor function
47. Regulation of cardiomyocyte signaling by RGS proteins: Differential selectivity towards G proteins and susceptibility to regulation
48. Selective Loss of Fine Tuning of Gq/11 Signaling by RGS2 Protein Exacerbates Cardiomyocyte Hypertrophy
49. Chronic Cardiac-Specific Thyrotoxicosis Increases Myocardial β-Adrenergic Responsiveness
50. Differential Contribution of GTPase Activation and Effector Antagonism to the Inhibitory Effect of RGS Proteins on Gq-mediated Signaling in Vivo
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