102 results on '"Kayagaki, Nobuhiko"'
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2. Cell death
3. Highly multiplexed, image-based pooled screens in primary cells and tissues with PerturbView
4. Inhibiting membrane rupture with NINJ1 antibodies limits tissue injury
5. Dying cells fan the flames of inflammation
6. Shigella ubiquitin ligase IpaH7.8 targets gasdermin D for degradation to prevent pyroptosis and enable infection
7. Evolutionary loss of inflammasomes in the Carnivora and implications for the carriage of zoonotic infections
8. Selective activation of PFKL suppresses the phagocytic oxidative burst
9. Discovery of a caspase cleavage motif antibody reveals insights into noncanonical inflammasome function
10. NINJ1 mediates plasma membrane rupture during lytic cell death
11. Evolutionary Loss of Inflammasomes in Carnivores to Facilitate Carriage of Zoonotic Infections
12. NINJ1 mediates plasma membrane rupture during lytic cell death
13. Rescue from a fiery death: A therapeutic endeavor
14. Correction: MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition
15. MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition
16. IRF2 transcriptionally induces GSDMD expression for pyroptosis
17. MCC950/CRID3 potently targets the NACHT domain of wildtype NLRP3 but not disease-associated mutants for inflammasome inhibition
18. Pathogen blockade of TAK1 triggers caspase-8–dependent cleavage of gasdermin D and cell death
19. Caspase-11 auto-proteolysis is crucial for noncanonical inflammasome activation
20. ASC- and caspase-8-dependent apoptotic pathway diverges from the NLRC4 inflammasome in macrophages
21. Faculty Opinions recommendation of Nlrp6- and ASC-Dependent Inflammasomes Do Not Shape the Commensal Gut Microbiota Composition.
22. Faculty Opinions recommendation of Depleting dietary valine permits nonmyeloablative mouse hematopoietic stem cell transplantation.
23. Structure-Based Design of Tricyclic NF-κB Inducing Kinase (NIK) Inhibitors That Have High Selectivity over Phosphoinositide-3-kinase (PI3K)
24. The Yersinia pestis Effector YopM Inhibits Pyrin Inflammasome Activation
25. GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes
26. Does caspase-12 suppress inflammasome activation?
27. Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
28. Caspase-11: arming the guards against bacterial infection
29. Interleukin-22 Induces Interleukin-18 Expression from Epithelial Cells during Intestinal Infection
30. Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells
31. Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases
32. Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4
33. Faculty Opinions recommendation of Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota.
34. Faculty Opinions recommendation of Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA.
35. Faculty Opinions recommendation of ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation.
36. Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1
37. Phosphorylation of NLRC4 is critical for inflammasome activation
38. Faculty Opinions recommendation of Promotion of hepatocellular carcinoma by the intestinal microbiota and TLR4.
39. Phosphorylation-dependent activity of the deubiquitinase DUBA
40. Faculty Opinions recommendation of STING is a direct innate immune sensor of cyclic di-GMP.
41. Non-canonical inflammasome activation targets caspase-11
42. Faculty Opinions recommendation of Cutting edge: reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome.
43. Faculty Opinions recommendation of Linear ubiquitination prevents inflammation and regulates immune signalling.
44. Faculty Opinions recommendation of Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria.
45. Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis
46. A Deubiquitinase That Regulates Type I Interferon Production
47. IAP Antagonists Induce Autoubiquitination of c-IAPs, NF-κB Activation, and TNFα-Dependent Apoptosis
48. Interferons elicete anti-tumor effects through induction of TRAIL on human peripheral T cells
49. Yersinia virulence factor YopJ acts as a deubiquitinase to inhibit NF-κB activation
50. TNF‐related apoptosis‐inducing ligand (TRAIL)/Apo2L suppresses experimental autoimmune encephalomyelitis in mice
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