67 results on '"Jonas, Jean-Christophe"'
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2. In depth functional characterization of human induced pluripotent stem cell-derived beta cells in vitro and in vivo
3. The lack of functional nicotinamide nucleotide transhydrogenase only moderately contributes to the impairment of glucose tolerance and glucose-stimulated insulin secretion in C57BL/6J vs C57BL/6N mice
4. Transcriptome analysis of islets from diabetes‐resistant and diabetes‐prone obese mice reveals novel gene regulatory networks involved in beta‐cell compensation and failure
5. Non-canonical mitochondrial STAT3 signaling mediates exercise-induced insulin secretion down-regulation
6. Emerging Roles of Metallothioneins in Beta Cell Pathophysiology: Beyond and above Metal Homeostasis and Antioxidant Response
7. Physiological ER Stress: The Model of Insulin-Secreting Pancreatic b-Cells
8. Inhibition of aquaporin-1 prevents myocardial remodeling by blocking the transmembrane transport of hydrogen peroxide
9. Editorial Overview: “Islet Biology in Type 2 Diabetes”
10. Nutrient Metabolism, Subcellular Redox State, and Oxidative Stress in Pancreatic Islets and β-Cells
11. Aspalathin Protects Insulin‐Producing β Cells against Glucotoxicity and Oxidative Stress‐Induced Cell Death
12. Exenatide induces frataxin expression and improves mitochondrial function in Friedreich ataxia
13. Proof-of-concept for 2D/CT element analysis of entire cryofrozen islets of Langerhans using a cryoloop synchrotron X-ray fluorescence setup
14. mRNA profiling of pancreatic beta-cells: investigating mechanisms of diabetes
15. Signal Transduction
16. Metallothionein 1 negatively regulates glucose-stimulated insulin secretion and is differentially expressed in conditions of beta cell compensation and failure in mice and humans
17. Phlda3 regulates beta cell survival during stress
18. Glucose Acutely Reduces Cytosolic and Mitochondrial H2O2in Rat Pancreatic Beta Cells
19. Pancreatic β-cell tRNA hypomethylation and fragmentation link TRMT10A deficiency with diabetes
20. Somatostatin Is Only Partly Required for the Glucagonostatic Effect of Glucose but Is Necessary for the Glucagonostatic Effect of KATP Channel Blockers
21. Glucolipotoxic conditions induce β-cell iron import, cytosolic ROS formation and apoptosis
22. Mechanisms of β-cell dedifferentiation in diabetes: recent findings and future research directions
23. Biomarkers of tumour redox status in response to modulations of glutathione and thioredoxin antioxidant pathways
24. NNT reverse mode of operation mediates glucose control of mitochondrial NADPH and glutathione redox state in mouse pancreatic β-cells
25. NADPH oxidase-2 does not contribute to β-cell glucotoxicity in cultured pancreatic islets from C57BL/6J mice
26. Hypoxia reduces ER-to-Golgi protein trafficking and increases cell death by inhibiting the adaptive unfolded protein response in mouse beta cells
27. Glucokinase activation is beneficial or toxic to cultured rat pancreatic islets depending on the prevailing glucose concentration
28. Unveiling a common mechanism of apoptosis in β-cells and neurons in Friedreich's ataxia
29. Acute nutrient regulation of the mitochondrial glutathione redox state in pancreatic β-cells
30. The Islet Estrogen Receptor-α Is Induced by Hyperglycemia and Protects Against Oxidative Stress-Induced Insulin-Deficient Diabetes
31. The molecular mechanisms of pancreatic β-cell glucotoxicity: Recent findings and future research directions
32. Protective Antioxidant and Antiapoptotic Effects of ZnCl2 in Rat Pancreatic Islets Cultured in Low and High Glucose Concentrations
33. MicroRNAs contribute to compensatory β cell expansion during pregnancy and obesity
34. HDLs Protect Pancreatic β-Cells Against ER Stress by Restoring Protein Folding and Trafficking
35. Dynamic measurements of mitochondrial hydrogen peroxide concentration and glutathione redox state in rat pancreatic β-cells using ratiometric fluorescent proteins: confounding effects of pH with HyPer but not roGFP1
36. Glucose-Induced O2 Consumption Activates Hypoxia Inducible Factors 1 and 2 in Rat Insulin-Secreting Pancreatic Beta-Cells
37. Role of activating transcription factor 3 in low glucose- and thapsigargin-induced apoptosis in cultured mouse islets
38. Mechanisms of Control of the Free Ca2+ Concentration in the Endoplasmic Reticulum of Mouse Pancreatic β-Cells
39. Endoplasmic reticulum accumulation of Kir6.2 without activation of ER stress response in islet cells from adult Sur1 knockout mice
40. Effects of c-MYC activation on glucose stimulus-secretion coupling events in mouse pancreatic islets
41. Glucose-induced Cytosolic pH Changes in β-Cells and Insulin Secretion Are Not Causally Related
42. Identification and subcellular localization of the Na+/H+ exchanger and a novel related protein in the endocrine pancreas and adrenal medulla
43. Probe-Independent and Direct Quantification of Insulin mRNA and Growth Hormone mRNA in Enriched Cell Preparations
44. Glucose-induced mixed [Ca2+]coscillations in mouse β-cells are controlled by the membrane potential and the SERCA3 Ca2+-ATPase of the endoplasmic reticulum
45. Mechanisms of Pancreatic β-Cell Death in Type 1 and Type 2 Diabetes
46. Induction of Adiponectin in Skeletal Muscle by Inflammatory Cytokines:in Vivoandin VitroStudies
47. Atypical Ca2+‐induced Ca2+ release from a sarco‐endoplasmic reticulum Ca2+‐ATPase 3‐dependent Ca2+ pool in mouse pancreatic β‐cells
48. Prolonged culture in low glucose induces apoptosis of rat pancreatic β-cells through induction of c-myc
49. Corticosteroids Induce Expression of Aquaporin-1 and Increase Transcellular Water Transport in Rat Peritoneum
50. SERCA3 Ablation Does Not Impair Insulin Secretion but Suggests Distinct Roles of Different Sarcoendoplasmic Reticulum Ca2+ Pumps for Ca2+ Homeostasis in Pancreatic β-cells
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