81 results on '"Johnstone, R. W."'
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2. Epigenetic targeting of Notch1-driven transcription using the HDACi panobinostat is a potential therapy against T-cell acute lymphoblastic leukemia
3. A pharmacogenomic approach validates AG-221 as an effective and on-target therapy in IDH2 mutant AML
4. HDAC3 activity is required for initiation of leukemogenesis in acute promyelocytic leukemia
5. Whole exome sequencing reveals activating JAK1 and STAT3 mutations in breast implant-associated anaplastic large cell lymphoma anaplastic large cell lymphoma
6. The SMAC mimetic, LCL-161, reduces survival in aggressive MYC-driven lymphoma while promoting susceptibility to endotoxic shock
7. A genome scale RNAi screen identifies GLI1 as a novel gene regulating vorinostat sensitivity
8. Scribble acts as an oncogene in Eμ-myc-driven lymphoma
9. A functional genomics screen identifies PCAF and ADA3 as regulators of human granzyme B-mediated apoptosis and Bid cleavage
10. CDK9 inhibition by dinaciclib potently suppresses Mcl-1 to induce durable apoptotic responses in aggressive MYC-driven B-cell lymphoma in vivo
11. The role of p21waf1/cip1 and p27Kip1 in HDACi-mediated tumor cell death and cell cycle arrest in the Eμ-myc model of B-cell lymphoma
12. Preclinical screening of histone deacetylase inhibitors combined with ABT-737, rhTRAIL/MD5-1 or 5-azacytidine using syngeneic Vk*MYC multiple myeloma
13. HDAC inhibitors induce tumor-cell-selective pro-apoptotic transcriptional responses
14. Thalidomide-analogue biology: immunological, molecular and epigenetic targets in cancer therapy
15. Oncogenes in Cell Survival and Cell Death
16. Translation inhibitors induce cell death by multiple mechanisms and Mcl-1 reduction is only a minor contributor
17. Induction of autophagy does not alter the anti-tumor effects of HDAC inhibitors
18. Granzyme B triggers a prolonged pressure to die in Bcl-2 overexpressing cells, defining a window of opportunity for effective treatment with ABT-737
19. Non-uniform residual stress assembly for free-space optical systems
20. Cell death research, on an island girt by sea
21. Histone deacetylase inhibitors are unable to synergize with ABT-737 in killing primary chronic lymphocytic leukaemia cells in vitro
22. Efficacy of CHK inhibitors as single agents in MYC-driven lymphoma cells
23. A scalable and modular lab-on-a-chip genetic analysis instrument
24. Overcoming Histone Deacetylase Inhibitor Induced Thrombocytopenia Using a Thrombopoietin Mimetic.
25. High Response Rates with the Combination of Bortezomib, Dexamethasone and the Pan-Histone Deacetylase Inhibitor Romidepsin in Patients with Relapsed or Refractory Multiple Myeloma in a Phase I/II Clinical Trial
26. Deep-UV patterning of commercial grade PMMA for low-cost, large-scale microfluidics
27. Self-sacrificial surface micromachining using poly(methyl methacrylate)
28. Polydimethylglutarimide (PMGI) as a sacrificial material for SU-8 surface-micromachining
29. Buckled cantilevers for out-of-plane platforms
30. Polydimethylglutarimide (PMGI) as a structural material for surface micromachining
31. Blocking granule-mediated death by primary human NK cells requires both protection of mitochondria and inhibition of caspase activity
32. Investigating the Use of a Bayesian Network to Model the Risk ofLyngbya majusculaBloom Initiation in Deception Bay, Queensland, Australia
33. Fabrication of an inexpensive cleanroom module for microsystem testing
34. Automated assembly of hingeless 90° out-of-plane microstructures
35. Analysis of the apoptotic and therapeutic activities of histone deacetylase inhibitors by using a mouse model of B cell lymphoma
36. Polymethylglutarimide As a Structural MEMS Material
37. SU-8 surface-micromachining process utilizing PMGI as a sacrificial material
38. Advanced monitoring systems for biological applications in marine environments
39. Non-uniform residual stresses for parallel assembly of out-of-plane surface-micromachined structures
40. Mutational analysis of P-glycoprotein: suppression of caspase activation in the absence of ATP-dependent drug efflux
41. P-glycoprotein inhibits caspase-8 activation but not formation of the death inducing signal complex (disc) following Fas ligation
42. A novel repressor, par-4, modulates transcription and growth suppression functions of the Wilms' tumor suppressor WT1
43. ANTE-PARTUM HAEMORRHAGE DUE TO PLACENTA PRAEVIA, ASSOCIATED WITH ALBUMINURIA AND ECLAMPSIA
44. Adenomyoma of the Uterus with Tuberculous Infection.*
45. Contribution to the Study of the Early Human Ovum based upon the investigation of I. A very early Ovum embedded in the Uterus and II. A very early Ovum embedded in the Infundibulum of the Tube.
46. Case of Concealed Accidental Hemorrhage with Eclampsia
47. WILLIAM SMELLIE'S BICENTENARY (1697-1763)
48. The Pathway of Obstetrics
49. Plea for Abolition of the Pelvimeter
50. INTERMEZZO
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