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126 results on '"Jacobs, Heinz"'

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1. Targeting DOT1L and EZH2 synergizes in breaking the germinal center identity of Diffuse Large B Cell Lymphoma

2. CD4+ T cells produce IFN-I to license cDC1s for induction of cytotoxic T-cell activity in human tumors

3. Broad Brush Surveys: a rapid qualitative assessment approach for water and sanitation infrastructure in urban sub-Saharan cities

4. Molecular dependencies and genomic consequences of a global DNA damage tolerance defect

7. DRAG in situ barcoding reveals an increased number of HSPCs contributing to myelopoiesis with age

8. Investigating the characteristics of residential end uses of water: A worldwide review

9. Mammalian life depends on two distinct pathways of DNA damage tolerance

10. Huwe1 supports B-cell development, B-cell-dependent immunity, somatic hypermutation and class switch recombination by regulating proliferation

13. DRAGin situbarcoding reveals an increased number of HSPCs contributing to myelopoiesis with age

15. DOT1L regulates lipid biosynthesis and inflammatory responses in macrophages and promotes atherosclerotic plaque stability

16. Division of labor within the DNA damage tolerance system reveals non-epistatic and clinically actionable targets for precision cancer medicine

17. Tumor-educated Tregs drive organ-specific metastasis in breast cancer by impairing NK cells in the lymph node niche

18. Multiple 9-1-1 complexes promote homolog synapsis, DSB repair, and ATR signaling during mammalian meiosis

19. Author response: Multiple 9-1-1 complexes promote homolog synapsis, DSB repair, and ATR signaling during mammalian meiosis

20. Tandem Substitutions in Somatic Hypermutation

22. Tandem Substitutions in Somatic Hypermutation

25. Multiple 9-1-1 complexes promote homolog synapsis, DSB repair, and ATR signaling during mammalian meiosis

27. The Widely Used Antihelmintic Drug Albendazole is a Potent Inducer of Loss of Heterozygosity

28. Histone methyltransferase DOT1L controls state‐specific identity during B cell differentiation

30. USP15 Deubiquitinase Safeguards Hematopoiesis and Genome Integrity in Hematopoietic Stem Cells and Leukemia Cells

31. The Ig heavy chain protein but not its message controls early B cell development

32. The histone methyltransferase DOT1L prevents antigen-independent differentiation and safeguards epigenetic identity of CD8 + T cells

34. Drinking Water Temperature around the Globe: Understanding, Policies, Challenges and Opportunities

35. Strategy for Development of Site-Specific Ubiquitin Antibodies

37. USP15 deubiquitinase safeguards hematopoiesis and genome integrity in hematopoietic stem cells and leukemia cells

38. USP15 Deubiquitinase Safeguards Hematopoiesis and Genome Integrity in Hematopoietic Stem Cells and Leukemia Cells

39. The histone methyltransferase DOT1L prevents antigen-independent differentiation and safeguards epigenetic identity of CD8+ T cells

40. Histone methyltransferase DOT1L controls state-specific identity during B cell differentiation

41. Repertoire Sequencing of B Cells Elucidates the Role of UNG and Mismatch Repair Proteins in Somatic Hypermutation in Humans

44. Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L‐dose dependency in HDAC1‐deficient thymic lymphoma

47. AKT inhibition impairs PCNA ubiquitylation and triggers synthetic lethality in homologous recombination-deficient cells submitted to replication stress

48. Evolutionarily-conserved chromatin crosstalk generates a DOT1L-dose dependency in thymic lymphoma caused by loss of HDAC1

49. Towards an understanding of C9orf82 protein/CAAP1 function

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