37 results on '"Gutteridge, Alex"'
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2. Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases
3. Network and pathway expansion of genetic disease associations identifies successful drug targets
4. Redesigning Metal Interference Screws Can Improve Ease of Insertion While Maintaining Fixation of Soft-Tissue Anterior Cruciate Ligament Reconstruction Grafts
5. Using transfer learning from prior reference knowledge to improve the clustering of single-cell RNA-Seq data
6. Benchmarking network propagation methods for disease gene identification
7. Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases
8. Benchmarking network propagation methods for disease gene identification
9. Single-cell RNAseq reveals seven classes of colonic sensory neuron
10. GI-530159, a novel, selective, mechanosensitive two-pore-domain potassium (K2P ) channel opener, reduces rat dorsal root ganglion neuron excitability
11. Transcriptomic and epigenetic regulation of disuse atrophy and the return to activity in skeletal muscle
12. GWAS of self-reported mosquito bite size, itch intensity and attractiveness to mosquitoes implicates immune-related predisposition loci
13. Interpreting transcriptional changes using causal graphs: new methods and their practical utility on public networks
14. Directing Differentiation of Pluripotent Stem Cells Toward Retinal Pigment Epithelium Lineage
15. Targeting the cAMP and Transforming Growth Factor-β Pathway Increases Proliferation to Promote Re-Epithelialization of Human Stem Cell-Derived Retinal Pigment Epithelium
16. Pharmacological reversal of a pain phenotype in iPSC-derived sensory neurons and patients with inherited erythromelalgia
17. Subtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic Release
18. Molecular Mechanisms Mediating Retinal Reactive Gliosis Following Bone Marrow Mesenchymal Stem Cell Transplantation
19. A FOXM1 Dependent Mesenchymal-Epithelial Transition in Retinal Pigment Epithelium Cells
20. Optimizing the Leveraging of Real-World Data to Improve the Development and Use of Medicines
21. Characterizing Human Stem Cell–derived Sensory Neurons at the Single-cell Level Reveals Their Ion Channel Expression and Utility in Pain Research
22. Precompetitive activity to address the biological data needs of drug discovery
23. Molecular causes of transcriptional response: a Bayesian prior knowledge approach
24. Novel Pancreatic Endocrine Maturation Pathways Identified by Genomic Profiling and Causal Reasoning
25. Directing Differentiation of Human Embryonic Stem Cells Toward Anterior Neural Ectoderm Using Small Molecules
26. The genetic control of growth rate: a systems biology study in yeast
27. Functional Expression of Parasite Drug Targets and Their Human Orthologs in Yeast
28. Nutrient control of eukaryote cell growth: a systems biology study in yeast
29. The DBCLS BioHackathon: standardization and interoperability for bioinformatics web services and workflows
30. Prediction of drug–target interaction networks from the integration of chemical and genomic spaces
31. Regulation of metabolic networks by small molecule metabolites
32. MIMOX: a web tool for phage display based epitope mapping
33. Understanding nature's catalytic toolkit
34. Effective function annotation through catalytic residue conservation
35. Conformational Changes Observed in Enzyme Crystal Structures upon Substrate Binding
36. Conformational change in substrate binding, catalysis and product release: an open and shut case?
37. Using A Neural Network and Spatial Clustering to Predict the Location of Active Sites in Enzymes
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