106 results on '"Gallagher, J.A."'
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2. Alkaptonuria ☆
3. Temporal adaptations in the phenylalanine/tyrosine pathway and related factors during nitisinone-induced tyrosinaemia in alkaptonuria
4. Characterization of changes in the tyrosine pathway by 24-h profiling during nitisinone treatment in alkaptonuria
5. Treatment of osteoporotic fractures in alkaptonuria by teriparatide stimulates bone formation and decreases fracture rate – A report of two cases
6. Alkaptonuria
7. What Rare Diseases Can Tell Us About OA
8. A comparison between high density mineralised protrusions identified in the knees of cadavers and in patients of the osteoarthritis initiative
9. Approaches for associating molecular polymorphisms with phenotypic traits based on linkage disequilibrium in natural populations of Lolium perenne
10. Interference of hydroxyphenylpyruvic acid, hydroxyphenyllactic acid and tyrosine on routine serum and urine clinical chemistry assays; implications for biochemical monitoring of patients with alkaptonuria treated with nitisinone
11. Raman Spectroscopy identifies differences in ochronotic and non-ochronotic cartilage; a potential novel technique for monitoring ochronosis
12. Extracellular chemical profiling by LC-QTOF-MS identifies novel bone resorption markers for monitoring progression of osteoarthropathy in the rare disease alkaptonuria
13. Osteoarthritic subchondral bone marrow histology. Lessons from changes in alkaptonuria
14. Data on items of AKUSSI in Alkaptonuria collected over three years from the United Kingdom National Alkaptonuria Centre and the impact of nitisinone
15. Nitisinone arrests ochronosis and decreases rate of progression of Alkaptonuria: Evaluation of the effect of nitisinone in the United Kingdom National Alkaptonuria Centre
16. Clinical and biochemical assessment of depressive symptoms in patients with Alkaptonuria before and after two years of treatment with nitisinone
17. Inflammatory and oxidative stress biomarkers in alkaptonuria: data from the DevelopAKUre project
18. Raman spectroscopy can non-invasively distinguish between ochronotic and non-ochronotic cartilage
19. Disruption of collagen triple helix hydrogen bonding in ochronotic human cartilage in alkaptonuria observed by dynamic nuclear polarisation-enhanced solid-state nuclear magnetic resonance spectroscopy
20. Combined LC-QTOF-MS urine metabolomics and 18F-NaF PET imaging indicates novel compounds associated with spine osteoarthropathy in the rare disease alkaptonuria
21. Generation and phenotyping of a targeted mouse model of alkaptonuria
22. Laser ablation machined sections permit correlative studies of hdmps by X-ray microtomography, optical and scanning electron microscopy
23. Longitudinal survey for high density mineralised protrusions identified by 3D dess MRI in patients of the osteoarthritis initiative
24. An Investigation of High Density Mineralised Protrusions in Human Cadaveric Knees by MRI and Microtomography
25. Anatomical distribution of 18F PET signal in patients with osteoarthropathy of alkaptonuria
26. The effect of elevated CO{sub 2} under field conditions on starch metabolism in white clover stolons
27. Identification of high density mineralised protrusions in human knees ex-vivo and in-situ by clinical scanning techniques
28. High density mineralised protrusions from the tidemark into hyaline cartilage in human joints
29. Analysis of cartilage biomarkers of aging and turnover in the osteoarthropathy of alkaptonuria
30. Urine homogentisic acid and tyrosine: Simultaneous analysis by liquid chromatography tandem mass spectrometry
31. Identification of concentric lamellae in the articular calcified cartilage of osteoarthritic mice
32. Rare syndromes: what they teach us about osteoarthritis disease mechanisms
33. Initiation and progression of ochronotic osteoarthropathy in alkaptonuric mice
34. Identification of subchondral protrusions by magnetic resonance imaging: a novel biomarker of joint degeneration
35. ATP-Stimulated ATP release and metabolic acid production:-regulating life and death decisions in articular chondrocytes
36. Ochronosis in a murine model of alkaptonuria is synonymous to that in the human condition
37. Seasonal variation in Laminaria digitata and its impact on biochemical conversion routes to biofuels
38. 159 ANALYSIS OF CARTILAGE BIOMARKERS OF TURNOVER AND AGING IN THE OSTEOARTHROPATHY OF ALKAPTONURIA
39. Advanced ochronosis of articular cartilage in aku provides an extreme model of focal unloading of bone due to stress shielding
40. Adiponectin receptors in multinucleated osteoclast-like cells
41. Seasonal variation in the chemical composition of the bioenergy feedstock Laminaria digitata for thermochemical conversion
42. 257 ELUCIDATING THE MECHANISM OF OSTEOARTHROPATHY IN ALKAPTONURIA: LESSONS FOR OSTEOARTHRITIS
43. 106 IDENTIFICATION OF JOINT OCHRONOSIS IN A MOUSE MODEL OF ALKAPTONURIA
44. Lipopolysaccharide (LPS) alters expression of incretin receptors in monocytic and hepatocytic cell lines
45. Type VI collagen plays a major role in adhesion of osteoblastic cells
46. Time course and mechanisms of the synergistic activation of osteoblastic cells by extracelluar ATP and PTH
47. Deposition of ochronotic pigment in articular cartilage in alkaptonuria is initiated near the tidemark and progresses to the articular surface
48. Absence of paramyxovirus RNA in cultures of pagetic bone cells and in pagetic bon
49. Application of reflected light microscopy to identify and quantitate resorption by isolated osteoclasts
50. 457 ULTRASTRUCTURAL ANALYSIS OF COLLAGEN IN THE ARTHROPATHY OF ALKAPTONURIA IN VIVO AND IN VITRO
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