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65 results on '"Fernandez-Barrena, Maite G."'

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1. FRI-466-YI Implications and therapeutic potential of neddylation for pediatric liver cancer: hepatoblastoma

2. FRI-464 Caspases compromise SLU7 and UPF1 stability and nonsensemediated RNA decay activity during hepatocarcinogenesis

3. FRI-555 New insights into the regulation of bile acids synthesis during the early stages of liver regeneration: a human and experimental study

4. Impact of G9a and DNMT1 expression in pancreatic cancer survival: new potential epigenetic therapeutic strategy

5. Therapeutic potential of targeting protein hyper-SUMOylation in cholangiocarcinoma

6. Pediatric liver cancer: Hepatoblastoma and Neddylation post-translational modification

7. Biomarkers of endothelial dysfunction in patients with non-alcoholic fatty liver disease (NAFLD)

8. Identification and experimental validation of druggable epigenetic targets in hepatoblastoma

9. Single-cell RNA sequencing in DIAMOND mice reveals differentially regulated pathways specifically associated with the transition from simple steatosis towards NASH

10. KLF5 upregulation is a common event in cholangiocarcinoma, acting as an oncogene and constituting a bad prognostic factor

11. Antitumoral activity of the G9a inhibitor EZM8266 in hepatocellular carcinoma: potential for combination with immune checkpoint inhibitors

21. DNA methylation regulates lncRNAs compromising hepatic identity during hepatocarcinogenesis

22. Targeting NAE1-mediated protein hyper-NEDDylation halts cholangiocarcinogenesis and impacts on tumor-stroma crosstalk in experimental models

23. Proteomic analysis of bile in the rat thioacetamide model reveals new mechanisms in human cholangiocarcinogenesis

24. The inhibition of the epigenetic efectors DNMT1 and G9a as a potential therapeutic strategy against the non-alcoholic fatty liver development

25. Plasma cell-free DNA methylation as biomarker for hepatocellular carcinoma

26. Targeting NAE1-mediated protein hyper-NEDDylation halts cholangiocarcinogenesis and impacts on tumour-stroma crosstalk in experimental models

27. New molecular mechanisms in cholangiocarcinoma: signals triggering interleukin-6 production in tumor cells and KRAS co-opted epigenetic mediators driving metabolic reprogramming

28. Epigenetic remodelling in human hepatocellular carcinoma

29. List of Contributors

30. FOSL1 promotes cholangiocarcinoma via transcriptional effectors that could be therapeutically targeted

31. Dual Targeting of G9a and DNA Methyltransferase‐1 for the Treatment of Experimental Cholangiocarcinoma

32. Fragile X mental retardation protein in intrahepatic cholangiocarcinoma: regulating the cancer cell behavior plasticity at the leading edge

33. Dual Pharmacological Targeting of HDACs and PDE5 Inhibits Liver Disease Progression in a Mouse Model of Biliary Inflammation and Fibrosis

35. GLI1/GLI2 functional interplay is required to control Hedgehog/GLI targets gene expression

36. Proteostasis improvement in cystic cholangiocytes alleviates endoplasmic reticulum stress and halts polycystic liver disease

37. SLU7 downregulation potentiates liver damage through hepatic de-differentiation

38. Epigenetic mechanism and metabolic reprogramming in fibrogenesis: dual targeting of G9a and DNA methyltransferase 1 for the inhibition of liver fibrosis

39. Dual inhibition of DNA methyltransferase 1 and the histone methyltransferase G9a as a new therapeutic strategy in hepatoblastoma

40. The splicing regulator SLU7 is required for DNMT1 protein stability and DNA methylation maintenance

42. THU-064-Identification of new epigenetic targets in hepatic fibrosis

43. PS-043-Dual targeting of G9a and DNM-methyltransferase-1 for the treatment of experimental cholangiocarcinoma

44. THU-468-SLU7 controls genome integrity: New role of truncated SRSF3 proteins

45. Bile acids, FGF15/19 and liver regeneration: From mechanisms to clinical applications

46. MicroRNA‐506 promotes primary biliary cholangitis–like features in cholangiocytes and immune activation

47. Engineered fibroblast growth factor 19 protects from acetaminophen-induced liver injury and stimulates aged liver regeneration in mice

48. Fibroblast growth factor 15/19 (FGF15/19) protects from diet-induced hepatic steatosis: development of an FGF19-based chimeric molecule to promote fatty liver regeneration

50. Regulation of GLI Underlies a Role for BET Bromodomains in Pancreatic Cancer Growth and the Tumor Microenvironment

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