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56 results on '"Diolaiti, Morgan E"'

1. De novodesign of drug-binding proteins with predictable binding energy and specificity

Author

Lu, Lei, primary, Gou, Xuxu, additional, Tan, Sophia K, additional, Mann, Samuel I., additional, Yang, Hyunjun, additional, Zhong, Xiaofang, additional, Gazgalis, Dimitrios, additional, Valdiviezo, Jesús, additional, Jo, Hyunil, additional, Wu, Yibing, additional, Diolaiti, Morgan E., additional, Ashworth, Alan, additional, Polizzi, Nicholas F., additional, and DeGrado, William F., additional

Published
2023
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2. A single inactivating amino acid change in the SARS-CoV-2 NSP3 Mac1 domain attenuates viral replication in vivo

Author

Taha, Taha Y., primary, Suryawanshi, Rahul K., additional, Chen, Irene P., additional, Correy, Galen J., additional, McCavitt-Malvido, Maria, additional, O’Leary, Patrick C., additional, Jogalekar, Manasi P., additional, Diolaiti, Morgan E., additional, Kimmerly, Gabriella R., additional, Tsou, Chia-Lin, additional, Gascon, Ronnie, additional, Montano, Mauricio, additional, Martinez-Sobrido, Luis, additional, Krogan, Nevan J., additional, Ashworth, Alan, additional, Fraser, James S., additional, and Ott, Melanie, additional

Published
2023
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3. Data from PLX038: A Long-Acting Topoisomerase I Inhibitor With Robust Antitumor Activity in ATM-Deficient Tumors and Potent Synergy With PARP Inhibitors

Author

Thomas, Anish, primary, Fontaine, Shaun D., primary, Diolaiti, Morgan E., primary, Desai, Parth, primary, Kumar, Rajesh, primary, Takahashi, Nobuyuki, primary, Sciuto, Linda, primary, Nichols, Samantha, primary, Ashworth, Alan, primary, Feng, Felix Y., primary, Ashley, Gary W., primary, Nguyen, Minh, primary, Pommier, Yves, primary, and Santi, Daniel V., primary

Published
2023
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6. Data from PLX038: A Long-Acting Topoisomerase I Inhibitor With Robust Antitumor Activity in ATM-Deficient Tumors and Potent Synergy With PARP Inhibitors

Author

Thomas, Anish, primary, Fontaine, Shaun D., primary, Diolaiti, Morgan E., primary, Desai, Parth, primary, Kumar, Rajesh, primary, Takahashi, Nobuyuki, primary, Sciuto, Linda, primary, Nichols, Samantha, primary, Ashworth, Alan, primary, Feng, Felix Y., primary, Ashley, Gary W., primary, Nguyen, Minh, primary, Pommier, Yves, primary, and Santi, Daniel V., primary

Published
2023
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9. Supplementary Data from PLX038: A Long-Acting Topoisomerase I Inhibitor With Robust Antitumor Activity in ATM-Deficient Tumors and Potent Synergy With PARP Inhibitors

Author

Thomas, Anish, primary, Fontaine, Shaun D., primary, Diolaiti, Morgan E., primary, Desai, Parth, primary, Kumar, Rajesh, primary, Takahashi, Nobuyuki, primary, Sciuto, Linda, primary, Nichols, Samantha, primary, Ashworth, Alan, primary, Feng, Felix Y., primary, Ashley, Gary W., primary, Nguyen, Minh, primary, Pommier, Yves, primary, and Santi, Daniel V., primary

Published
2023
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20. Supplementary Data from PLX038: A Long-Acting Topoisomerase I Inhibitor With Robust Antitumor Activity in ATM-Deficient Tumors and Potent Synergy With PARP Inhibitors

Author

Thomas, Anish, primary, Fontaine, Shaun D., primary, Diolaiti, Morgan E., primary, Desai, Parth, primary, Kumar, Rajesh, primary, Takahashi, Nobuyuki, primary, Sciuto, Linda, primary, Nichols, Samantha, primary, Ashworth, Alan, primary, Feng, Felix Y., primary, Ashley, Gary W., primary, Nguyen, Minh, primary, Pommier, Yves, primary, and Santi, Daniel V., primary

Published
2023
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37. Supplementary Data from Resistance to ATR Inhibitors Is Mediated by Loss of the Nonsense-Mediated Decay Factor UPF2

Author

O'Leary, Patrick C., primary, Chen, Huadong, primary, Doruk, Yagmur U., primary, Williamson, Tess, primary, Polacco, Benjamin, primary, McNeal, Andrew S., primary, Shenoy, Tanushree, primary, Kale, Nupura, primary, Carnevale, Julia, primary, Stevenson, Erica, primary, Quigley, David A., primary, Chou, Jonathan, primary, Feng, Felix Y., primary, Swaney, Danielle L., primary, Krogan, Nevan J., primary, Kim, Minkyu, primary, Diolaiti, Morgan E., primary, and Ashworth, Alan, primary

Published
2023
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38. Supplementary Figure from Resistance to ATR Inhibitors Is Mediated by Loss of the Nonsense-Mediated Decay Factor UPF2

Author

O'Leary, Patrick C., primary, Chen, Huadong, primary, Doruk, Yagmur U., primary, Williamson, Tess, primary, Polacco, Benjamin, primary, McNeal, Andrew S., primary, Shenoy, Tanushree, primary, Kale, Nupura, primary, Carnevale, Julia, primary, Stevenson, Erica, primary, Quigley, David A., primary, Chou, Jonathan, primary, Feng, Felix Y., primary, Swaney, Danielle L., primary, Krogan, Nevan J., primary, Kim, Minkyu, primary, Diolaiti, Morgan E., primary, and Ashworth, Alan, primary

Published
2023
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39. Supplementary Data from Resistance to ATR Inhibitors Is Mediated by Loss of the Nonsense-Mediated Decay Factor UPF2

Author

O'Leary, Patrick C., primary, Chen, Huadong, primary, Doruk, Yagmur U., primary, Williamson, Tess, primary, Polacco, Benjamin, primary, McNeal, Andrew S., primary, Shenoy, Tanushree, primary, Kale, Nupura, primary, Carnevale, Julia, primary, Stevenson, Erica, primary, Quigley, David A., primary, Chou, Jonathan, primary, Feng, Felix Y., primary, Swaney, Danielle L., primary, Krogan, Nevan J., primary, Kim, Minkyu, primary, Diolaiti, Morgan E., primary, and Ashworth, Alan, primary

Published
2023
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40. Supplementary Data from Resistance to ATR Inhibitors Is Mediated by Loss of the Nonsense-Mediated Decay Factor UPF2

Author

O'Leary, Patrick C., primary, Chen, Huadong, primary, Doruk, Yagmur U., primary, Williamson, Tess, primary, Polacco, Benjamin, primary, McNeal, Andrew S., primary, Shenoy, Tanushree, primary, Kale, Nupura, primary, Carnevale, Julia, primary, Stevenson, Erica, primary, Quigley, David A., primary, Chou, Jonathan, primary, Feng, Felix Y., primary, Swaney, Danielle L., primary, Krogan, Nevan J., primary, Kim, Minkyu, primary, Diolaiti, Morgan E., primary, and Ashworth, Alan, primary

Published
2023
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41. Supplementary Figure from Resistance to ATR Inhibitors Is Mediated by Loss of the Nonsense-Mediated Decay Factor UPF2

Author

O'Leary, Patrick C., primary, Chen, Huadong, primary, Doruk, Yagmur U., primary, Williamson, Tess, primary, Polacco, Benjamin, primary, McNeal, Andrew S., primary, Shenoy, Tanushree, primary, Kale, Nupura, primary, Carnevale, Julia, primary, Stevenson, Erica, primary, Quigley, David A., primary, Chou, Jonathan, primary, Feng, Felix Y., primary, Swaney, Danielle L., primary, Krogan, Nevan J., primary, Kim, Minkyu, primary, Diolaiti, Morgan E., primary, and Ashworth, Alan, primary

Published
2023
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42. Supplementary Data from Resistance to ATR Inhibitors Is Mediated by Loss of the Nonsense-Mediated Decay Factor UPF2

Author

O'Leary, Patrick C., primary, Chen, Huadong, primary, Doruk, Yagmur U., primary, Williamson, Tess, primary, Polacco, Benjamin, primary, McNeal, Andrew S., primary, Shenoy, Tanushree, primary, Kale, Nupura, primary, Carnevale, Julia, primary, Stevenson, Erica, primary, Quigley, David A., primary, Chou, Jonathan, primary, Feng, Felix Y., primary, Swaney, Danielle L., primary, Krogan, Nevan J., primary, Kim, Minkyu, primary, Diolaiti, Morgan E., primary, and Ashworth, Alan, primary

Published
2023
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44. Resistance to ATR Inhibitors Is Mediated by Loss of the Nonsense-Mediated Decay Factor UPF2

Author

O'Leary, Patrick C., primary, Chen, Huadong, additional, Doruk, Yagmur U., additional, Williamson, Tess, additional, Polacco, Benjamin, additional, McNeal, Andrew S., additional, Shenoy, Tanushree, additional, Kale, Nupura, additional, Carnevale, Julia, additional, Stevenson, Erica, additional, Quigley, David A., additional, Chou, Jonathan, additional, Feng, Felix Y., additional, Swaney, Danielle L., additional, Krogan, Nevan J., additional, Kim, Minkyu, additional, Diolaiti, Morgan E., additional, and Ashworth, Alan, additional

Published
2022
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45. RASA2 ablation in T cells boosts antigen sensitivity and long-term function

Author

Carnevale, Julia, primary, Shifrut, Eric, additional, Kale, Nupura, additional, Nyberg, William A., additional, Blaeschke, Franziska, additional, Chen, Yan Yi, additional, Li, Zhongmei, additional, Bapat, Sagar P., additional, Diolaiti, Morgan E., additional, O’Leary, Patrick, additional, Vedova, Shane, additional, Belk, Julia, additional, Daniel, Bence, additional, Roth, Theodore L., additional, Bachl, Stefanie, additional, Anido, Alejandro Allo, additional, Prinzing, Brooke, additional, Ibañez-Vega, Jorge, additional, Lange, Shannon, additional, Haydar, Dalia, additional, Luetke-Eversloh, Marie, additional, Born-Bony, Maelys, additional, Hegde, Bindu, additional, Kogan, Scott, additional, Feuchtinger, Tobias, additional, Okada, Hideho, additional, Satpathy, Ansuman T., additional, Shannon, Kevin, additional, Gottschalk, Stephen, additional, Eyquem, Justin, additional, Krenciute, Giedre, additional, Ashworth, Alan, additional, and Marson, Alexander, additional

Published
2022
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46. PLX038: A Long-Acting Topoisomerase I Inhibitor With Robust Antitumor Activity in ATM-Deficient Tumors and Potent Synergy With PARP Inhibitors

Author

Thomas, Anish, primary, Fontaine, Shaun D., additional, Diolaiti, Morgan E., additional, Desai, Parth, additional, Kumar, Rajesh, additional, Takahashi, Nobuyuki, additional, Sciuto, Linda, additional, Nichols, Samantha, additional, Ashworth, Alan, additional, Feng, Felix Y., additional, Ashley, Gary W., additional, Nguyen, Minh, additional, Pommier, Yves, additional, and Santi, Daniel V., additional

Published
2022
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48. A protein interaction landscape of breast cancer

Author

Kim, Minkyu, primary, Park, Jisoo, additional, Bouhaddou, Mehdi, additional, Kim, Kyumin, additional, Rojc, Ajda, additional, Modak, Maya, additional, Soucheray, Margaret, additional, McGregor, Michael J., additional, O’Leary, Patrick, additional, Wolf, Denise, additional, Stevenson, Erica, additional, Foo, Tzeh Keong, additional, Mitchell, Dominique, additional, Herrington, Kari A., additional, Muñoz, Denise P., additional, Tutuncuoglu, Beril, additional, Chen, Kuei-Ho, additional, Zheng, Fan, additional, Kreisberg, Jason F., additional, Diolaiti, Morgan E., additional, Gordan, John D., additional, Coppé, Jean-Philippe, additional, Swaney, Danielle L., additional, Xia, Bing, additional, van ’t Veer, Laura, additional, Ashworth, Alan, additional, Ideker, Trey, additional, and Krogan, Nevan J., additional

Published
2021
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50. Design and Synthesis of Poly(ADP-ribose) Polymerase Inhibitors: Impact of Adenosine Pocket-Binding Motif Appendage to the 3-Oxo-2,3-dihydrobenzofuran-7-carboxamide on Potency and Selectivity

Author

Velagapudi, Uday Kiran, primary, Langelier, Marie-France, additional, Delgado-Martin, Cristina, additional, Diolaiti, Morgan E., additional, Bakker, Sietske, additional, Ashworth, Alan, additional, Patel, Bhargav A., additional, Shao, Xuwei, additional, Pascal, John M., additional, and Talele, Tanaji T., additional

Published
2019
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