98 results on '"Castilla, Joaquín"'
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2. A Protein Misfolding Shaking Amplification-based method for the spontaneous generation of hundreds of bona fide prions
3. Laboratory Identification of Prion Infections
4. A tetracationic porphyrin with dual anti-prion activity
5. Understanding the key features of the spontaneous formation of bona fide prions through a novel methodology that enables their swift and consistent generation
6. A tetracationic porphyrin with dual anti-prion activity
7. Bona fide atypical scrapie faithfully reproduced for the first time in a rodent model
8. Glycans are not necessary to maintain the pathobiological features of bovine spongiform encephalopathy
9. A Quick Method to Evaluate the Effect of the Amino Acid Sequence in the Misfolding Proneness of the Prion Protein
10. Description of the first Spanish case of Gerstmann–Sträussler–Scheinker disease with A117V variant: clinical, histopathological and biochemical characterization
11. Biosemiotics comprehension of PrP code and prion disease
12. Homozygous R136S mutation in PRNP gene causes inherited early onset prion disease
13. Solid state NMR reveals a parallel in register architecture for an infectious recombinant prion
14. Sporadic Creutzfeldt–Jakob disease with extremely long 14‐year survival period
15. Cerebrospinal Fluid and Plasma Small Extracellular Vesicles and miRNAs as Biomarkers for Prion Diseases
16. Improving the Pharmacological Properties of Ciclopirox for Its Use in Congenital Erythropoietic Porphyria
17. Homozygous R136S mutation in PRNP gene causes recessive inherited early onset prion disease
18. Detection of chronic wasting disease in mule and white-tailed deer by RT-QuIC analysis of outer ear
19. Prion-Associated Neurodegeneration Causes Both Endoplasmic Reticulum Stress and Proteasome Impairment in a Murine Model of Spontaneous Disease
20. A Novel, Reliable and Highly Versatile Method to Evaluate Different Prion Decontamination Procedures
21. Evaluation of the Influence of Astrocytes on In Vitro Blood–Brain Barrier Models
22. Structural features of an infectious recombinant PrPSc prion using solid state NMR
23. Detection of Pathognomonic Biomarker PrPSc and the Contribution of Cell Free-Amplification Techniques to the Diagnosis of Prion Diseases
24. Dogs are resistant to prion infection, due to the presence of aspartic or glutamic acid at position 163 of their prion protein
25. Protein Misfolding Cyclic Amplification for Diagnosis and Prion Propagation Studies
26. Interference of Coronavirus Infection by Expression of IgG or IgA Virus Neutralizing Antibodies
27. Development of Protection against Coronavirus Induced Diseases
28. Development of a new largely scalable in vitro prion propagation method for the production of infectious recombinant prions for high resolution structural studies
29. The amino acid residue in position 163 of canine PrPC is critical to the exceptional resistance of dogs to prion infections: evidence from transgenic mouse models
30. Autoantibodies against the prion protein in individuals with PRNP mutations
31. A Single Amino Acid Substitution, Found in Mammals with Low Susceptibility to Prion Diseases, Delays Propagation of Two Prion Strains in Highly Susceptible Transgenic Mouse Models
32. Análisis cualitativo del impacto social y familiar de las encefalopatías espongiformes transmisibles humanas
33. Insights into the Bidirectional Properties of the Sheep–Deer Prion Transmission Barrier
34. Repurposing ciclopirox as a pharmacological chaperone in a model of congenital erythropoietic porphyria
35. Detection of amyloid fibrils in Parkinson’s disease using plasmonic chirality
36. Behind the potential evolution towards prion resistant species
37. Recombinant PrPSc shares structural features with brain-derived PrPSc: Insights from limited proteolysis
38. An Amino Acid Substitution Found in Animals with Low Susceptibility to Prion Diseases Confers a Protective Dominant-Negative Effect in Prion-Infected Transgenic Mice
39. In Vitro Approach To Identify Key Amino Acids in Low Susceptibility of Rabbit Prion Protein to Misfolding
40. Recombinant PrP and Its Contribution to Research on Transmissible Spongiform Encephalopathies
41. Unraveling the key to the resistance of canids to prion diseases
42. Cofactors influence the biological properties of infectious recombinant prions
43. Soluble polymorphic bank vole prion proteins induced by co-expression of quiescin sulfhydryl oxidase in E. coli and their aggregation behaviors
44. Generation of a new infectious recombinant prion: a model to understand Gerstmann–Sträussler–Scheinker syndrome
45. An antipsychotic drug exerts anti-prion effects by altering the localization of the cellular prion protein
46. iPS Cell Cultures from a Gerstmann-Sträussler-Scheinker Patient with the Y218N PRNP Mutation Recapitulate tau Pathology
47. Protein misfolding cyclic amplification corroborates the absence of PrP Sc accumulation in placenta from foetuses with the ARR/ARQ genotype in natural scrapie
48. Prion-like disorders and Transmissible Spongiform Encephalopathies: An overview of the mechanistic features that are shared by the various disease-related misfolded proteins
49. Prion replication without host adaptation during interspecies transmissions
50. A cationic tetrapyrrole inhibits toxic activities of the cellular prion protein
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