143 results on '"Brierley, Stuart M"'
Search Results
2. Comparative localization of colorectal sensory afferent central projections in the mouse spinal cord dorsal horn and caudal medulla dorsal vagal complex
3. Gastrointestinal Sensation; General Principles
4. Peripheral and central neuroplasticity in a mouse model of endometriosis
5. Gut enterochromaffin cells drive visceral pain and anxiety
6. The voltage‐gated sodium channelNa V 1.7 underlies endometriosis‐associated chronic pelvic pain
7. Extrinsic Sensory Afferent Nerves Innervating the Gastrointestinal Tract in Health and Disease
8. Contributors
9. The T-type calcium channel CaV3.2 regulates bladder afferent responses to mechanical stimuli
10. The voltage-gated sodium channel NaV1.7 underlies endometriosis-associated chronic pelvic pain
11. Targeting the endocannabinoid system for the treatment of abdominal pain in irritable bowel syndrome
12. Disengaging spinal afferent nerve communication with the brain in live mice
13. TGR5 agonists induce peripheral and central hypersensitivity to bladder distension
14. Gut Enterochromaffin Cells are Critical Drivers of Visceral Pain and Anxiety
15. Guanylate cyclase-C agonists as peripherally acting treatments of chronic visceral pain
16. Clodronate Treatment Prevents Vaginal Hypersensitivity in a Mouse Model of Vestibulodynia
17. Orai1‐ and Orai2‐, but not Orai3‐mediated I CRAC is regulated by intracellular pH
18. A syngeneic inoculation mouse model of endometriosis that develops multiple comorbid visceral and cutaneous pain like behaviours
19. Design of a Stable Cyclic Peptide Analgesic Derived from Sunflower Seeds that Targets the κ-Opioid Receptor for the Treatment of Chronic Abdominal Pain
20. Pharmacological Inhibition of the Voltage-Gated Sodium Channel NaV1.7 Alleviates Chronic Visceral Pain in a Rodent Model of Irritable Bowel Syndrome
21. Pruritogenic mechanisms and gut sensation: putting the “irritant” into irritable bowel syndrome
22. Olorinab (APD371), a peripherally acting, highly selective, full agonist of the cannabinoid receptor 2, reduces colitis-induced acute and chronic visceral hypersensitivity in rodents
23. A mouse model of endometriosis that displays vaginal, colon, cutaneous, and bladder sensory comorbidities
24. Activation of MrgprA3 and MrgprC11 on Bladder-Innervating Afferents Induces Peripheral and Central Hypersensitivity to Bladder Distension
25. Food for thought about the immune drivers of gut pain
26. Activation of MrgprA3 and MrgprC11 on bladder-innervating afferents induces peripheral and central hypersensitivity to bladder distension
27. Orai1- and Orai2-, but not Orai3-mediated ICRAC is regulated by intracellular pH
28. Identification of a Quorum Sensing-Dependent Communication Pathway Mediating Bacteria-Gut-Brain Cross Talk
29. Experimentally Induced Bladder Permeability Evokes Bladder Afferent Hypersensitivity in the Absence of Inflammation
30. Pain in Endometriosis
31. Experimental Colitis Models
32. Contributors
33. Innervation of the Gastrointestinal Tract by Spinal and Vagal Afferent Nerves
34. Pharmacological modulation of voltage-gated sodium (NaV) channels alters nociception arising from the female reproductive tract
35. A spider-venom peptide with multitarget activity on sodium and calcium channels alleviates chronic visceral pain in a model of irritable bowel syndrome
36. Structure, Function, and Therapeutic Potential of the Trefoil Factor Family in the Gastrointestinal Tract
37. Effects and sites of action of a M1 receptor positive allosteric modulator on colonic motility in rats and dogs compared with 5‐HT 4 agonism and cholinesterase inhibition
38. Histamine induces peripheral and central hypersensitivity to bladder distension via the histamine H1 receptor and TRPV1
39. Gut nociceptors: sentinels promoting host defense
40. Purinergic receptor mediated calcium signalling in urothelial cells
41. Activation of pruritogenic TGR5, MrgprA3, and MrgprC11 on colon-innervating afferents induces visceral hypersensitivity
42. Colonic afferent input and dorsal horn neuron activation differs between the thoracolumbar and lumbosacral spinal cord
43. Innate immune response to bacterial urinary tract infection sensitises high-threshold bladder afferents and recruits silent nociceptors
44. Linaclotide treatment reduces endometriosis-associated vaginal hyperalgesia and mechanical allodynia through viscerovisceral cross-talk
45. Na V 1.6 regulates excitability of mechanosensitive sensory neurons
46. Trefoil Factor Family: Unresolved Questions and Clinical Perspectives
47. Visceral Pain
48. P139 OLORINAB, A PERIPHERALLY RESTRICTED, HIGHLY SELECTIVE AGONIST OF THE CANNABINOID RECEPTOR TYPE 2 FOR THE MANAGEMENT OF VISCERAL PAIN IN INFLAMMATORY BOWEL DISEASE (IBD) – PRECLINICAL AND EARLY CLINICAL DEVELOPMENT
49. P139 OLORINAB, A PERIPHERALLY RESTRICTED, HIGHLY SELECTIVE AGONIST OF THE CANNABINOID RECEPTOR TYPE 2 FOR THE MANAGEMENT OF VISCERAL PAIN IN INFLAMMATORY BOWEL DISEASE (IBD) – PRECLINICAL AND EARLY CLINICAL DEVELOPMENT
50. Mechanisms Underlying Overactive Bladder and Interstitial Cystitis/Painful Bladder Syndrome
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