174 results on '"Bowden, Jack"'
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2. Exploring and accounting for genetically driven effect heterogeneity in Mendelian Randomization
3. SLCO1B1 Exome Sequencing and Statin Treatment Response in 64,000 UK Biobank Patients
4. Polygenic scores for cardiovascular risk factors improve estimation of clinical outcomes in CCB treatment compared to pharmacogenetic variants alone
5. Robust use of phenotypic heterogeneity at drug target genes for mechanistic insights: Application of cis‐multivariable Mendelian randomization to GLP1R gene region
6. Effects of physical activity and sedentary time on depression, anxiety and well-being: a bidirectional Mendelian randomisation study
7. Body mass index and inflammation in depression and treatment-resistant depression: a Mendelian randomisation study
8. Association between circadian physical activity patterns and mortality in the UK Biobank
9. Smoking during pregnancy and its effect on placental weight: A Mendelian randomization study
10. Phenotype-based targeted treatment of SGLT2 inhibitors and GLP-1 receptor agonists in type 2 diabetes
11. Mid‐life leukocyte telomere length and dementia risk: An observational and mendelian randomization study of 435,046 UK Biobank participants
12. Sparse dimensionality reduction approaches in Mendelian randomization with highly correlated exposures
13. Estimating and visualising multivariable Mendelian randomization analyses within a radial framework
14. Using clustering of genetic variants in Mendelian randomization to interrogate the causal pathways underlying multimorbidity
15. Combining pharmacogenetics and patient characteristic polygenic scores to improve outcome prediction for Calcium Channel Blocker treatment
16. Weak and pleiotropy robust sex‐stratified Mendelian randomization in the one sample and two sample settings
17. Incorporating discovery and replication GWAS into summary data Mendelian randomization studies: A review of current methods and a simple, general and powerful alternative
18. Association between circadian physical activity patterns and mortality in the UK Biobank
19. The causal role of accelerometer-derived sleep traits on glycated haemoglobin: a Mendelian randomization study
20. Calcium‐channel blockers: Clinical outcome associations with reported pharmacogenetics variants in 32 000 patients
21. Investigating a possible causal relationship between maternal serum urate concentrations and offspring birthweight: a Mendelian randomization study
22. Body Mass Index And Inflammation In Depression And Treatment-Resistant Depression: A Mendelian Randomization Study
23. Islet Autoantibody Level Distribution in Type 1 Diabetes and Their Association With Genetic and Clinical Characteristics
24. Interaction-based Mendelian randomization with measured and unmeasured gene-by-covariate interactions
25. Should RECOVERY have used response adaptive randomisation? Evidence from a simulation study
26. Dirichlet process mixture models to estimate outcomes for individuals with missing predictor data: application to predict optimal type 2 diabetes therapy in electronic health record data
27. Sample-constrained partial identification with application to selection bias
28. Mid-life leukocyte telomere length and dementia risk: a prospective cohort study of 435,046 UK Biobank participants
29. Sparse Dimensionality Reduction Approaches in Mendelian Randomization with highly correlated exposures
30. Assessing the Causal Role of Sleep Traits on Glycated Hemoglobin: A Mendelian Randomization Study
31. Assessing the Causal Role of Sleep Traits on Glycated Hemoglobin: A Mendelian Randomization Study
32. Assessing the Causal Role of Sleep Traits on Glycated Hemoglobin: A Mendelian Randomization Study
33. Calcium Channel Blockers: clinical outcome associations with reported pharmacogenetics variants in 32,000 patients
34. Investigating a possible causal relationship between maternal serum urate concentrations and offspring birthweight: A Mendelian randomization study
35. Statin treatment effectiveness and the SLCO1B1 *5 reduced function genotype: Long‐term outcomes in women and men
36. Sensitivity to missing not at random dropout in clinical trials: Use and interpretation of the trimmed means estimator
37. Profile‐likelihood Bayesian model averaging for two‐sample summary data Mendelian randomization in the presence of horizontal pleiotropy
38. Analysis ofCYP2C19genetic variants with ischaemic events in UK patients prescribed clopidogrel in primary care: a retrospective cohort study
39. Should RECOVERY have used Response Adaptive Randomization? Evidence from a simulation study
40. Statin treatment effectiveness and the SLCO1B1*5 reduced function genotype: long-term outcomes in women and men
41. W59. PHYSICAL ACTIVITY AND MENTAL HEALTH: A MENDELIAN RANDOMIZATION STUDY
42. TU35. INFLAMMATION AND OVERWEIGHT AS PUTATIVE RISK FACTORS FOR DEPRESSION: A MULTIVARIABLE MENDELIAN RANDOMIZATION STUDY
43. TH31. HIGHER BMI CAUSES LOWER ODDS OF DEPRESSION IN INDIVIDUALS OF EAST ASIAN ANCESTRY
44. The Triangulation WIthin a STudy (TWIST) framework for causal inference within pharmacogenetic research
45. Should RECOVERY have used Response Adaptive Randomization? Evidence from a simulation study
46. Exploiting collider bias to apply two-sample summary data Mendelian randomization methods to one-sample individual level data
47. Islet autoantibody level distributions in type 1 diabetes and their association with genetic and clinical characteristics
48. The Confidence Interval Method for Selecting Valid Instrumental Variables
49. Testing and correcting for weak and pleiotropic instruments in two‐sample multivariable Mendelian randomization
50. Connecting Instrumental Variable methods for causal inference to the Estimand Framework
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