35 results on '"Belema Makonen"'
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2. Potent Long-Acting Inhibitors Targeting the HIV-1 Capsid Based on a Versatile Quinazolin-4-one Scaffold
3. Scaffold modifications to the 4-(4,4-dimethylpiperidinyl) 2,6-dimethylpyridinyl class of HIV-1 allosteric integrase inhibitors
4. Discovery and Preclinical Profiling of GSK3839919, a Potent HIV-1 Allosteric Integrase Inhibitor
5. Case History: The Discovery of the First Hepatitis C Virus NS5A Replication Complex Inhibitor Daclatasvir (Daklinza™)
6. Daclatasvir (Daklinza): The First-in-Class HCV NS5A Replication Complex Inhibitor
7. Discovery and Clinical Validation of HCV Inhibitors Targeting the NS5A Protein
8. Hepatitis C Virus—Progress Toward Inhibiting the Nonenzymatic Viral Proteins
9. Facile Access to 1,4-Disubstituted Pyrrolo[1,2-a]pyrazines from α-Aminoacetonitriles
10. Development of the Large-Scale Synthesis of Tetrahydropyran Glycine, a Precursor to the HCV NS5A Inhibitor BMS-986097
11. Synergistic Activity of Combined NS5A Inhibitors
12. Resensitizing daclatasvir-resistant hepatitis C variants by allosteric modulation of NS5A
13. Discovery of Daclatasvir, a Pan-Genotypic Hepatitis C Virus NS5A Replication Complex Inhibitor with Potent Clinical Effect
14. Hepatitis C Virus NS5A Replication Complex Inhibitors: The Discovery of Daclatasvir
15. Discovery and Development of Hepatitis C Virus NS5A Replication Complex Inhibitors
16. Hepatitis C Virus NS5A Replication Complex Inhibitors. Part 6: Discovery of a Novel and Highly Potent Biarylimidazole Chemotype with Inhibitory Activity Toward Genotypes 1a and 1b Replicons
17. A scalable synthesis of (1R,3S,5R)-2-(tert-butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic acid
18. Characterizations of HCV NS5A replication complex inhibitors
19. HCV NS5A replication complex inhibitors. Part 5: Discovery of potent and pan-genotypic glycinamide cap derivatives
20. HCV NS5A Replication Complex Inhibitors. Part 4.1 Optimization for Genotype 1a Replicon Inhibitory Activity
21. Antiviral Drug Discovery
22. HCV NS5A replication complex inhibitors. Part 3: discovery of potent analogs with distinct core topologies
23. HCV NS5A replication complex inhibitors. Part 2: Investigation of stilbene prolinamides
24. The effects of NS5A inhibitors on NS5A phosphorylation, polyprotein processing and localization
25. Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect
26. Synthesis and structure–activity relationship of imidazo(1,2-a)thieno(3,2-e)pyrazines as IKK-β inhibitors
27. Synthesis and biological evaluation of 4-amino derivatives of benzimidazoquinoxaline, benzimidazoquinoline, and benzopyrazoloquinazoline as potent IKK inhibitors
28. Developments in Antiviral Drug Design, Discovery and Development in 2004
29. Synthesis of 1,1-Diarylethylenes from an α-Stannyl β-Silylstyrene.
30. Synthesis of 1,1-diarylethylenes from an α-stannyl β-silylstyrene
31. Synthesis of carbon-14 labeled (R)-3-fluoro-4-(2?-(5??, 6??, 7??, 8??-tetrahydro-5??, 5??, 8??, 8??-tetramethyl-2??-naphthyl)-[2?-hydroxy-14C])[carbonyl-14C]acetamidobenzoic acid
32. Triethyl Orthoacetate
33. Enantiomer discrimination illustrated by high-resolution crystal structures of the human nuclear receptor hRARγ
34. Chiral Aziridinyl Radicals: An Application to the Synthesis of the Core Nucleus of FR-900482
35. Cyclization of Chiral Carbon-Centered Aziridinyl Radicals: A New Route to Azirino[2',3':3,4]pyrrolo[1,2-a]indoles
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