99 results on '"Balaram, Hemalatha"'
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2. Enantioselectivity in the enzymatic dehydration of malate and tartrate: Mirror image specificities of structurally similar dehydratases
3. GMP Synthetase: Allostery, Structure, and Function
4. Enantioselectivity in the Enzymatic Dehydration of Malate and Tartrate: Mirror Image Specificities of Structurally Similar Dehydratases
5. Revisiting the Burden Borne by Fumarase: Enzymatic Hydration of an Olefin
6. Revisiting the burden borne by fumarase: enzymatic hydration of an olefin
7. Mechanistic Insights into the Functioning of a Two-Subunit GMP Synthetase, an Allosterically Regulated, Ammonia Channeling Enzyme
8. Tertiary and Quaternary Structure Organization in GMP Synthetases: Implications for Catalysis
9. Mechanistic insights into the functioning of GMP synthetase: a two-subunit, allosterically regulated, ammonia tunnelling enzyme
10. Structural basis for the hyperthermostability of an archaeal enzyme induced by succinimide formation
11. Structural basis for the hyperthermostability of an archaeal glutaminase induced by post-translational succinimide formation
12. Leptospira interrogans triosephosphate isomerase: exploring the structural determinants of stability, high reaction rate and specificity.
13. Toward Developing Intuitive Rules for Protein Variant Effect Prediction Using Deep Mutational Scanning Data
14. Structure and catalytic regulation of Plasmodium falciparum IMP specific nucleotidase
15. Helices on Interdomain Interface Couple Catalysis in the ATPPase Domain with Allostery in Plasmodium falciparum GMP Synthetase
16. Correction: Phosphoglycolate phosphatase is a metabolic proofreading enzyme essential for cellular function in Plasmodium berghei.
17. Helices on interdomain interface couple catalysis in the ATPPase domain with allostery inPlasmodium falciparumGMP synthetase
18. How a purine salvage enzyme singles out the right base
19. Biochemical and physiological investigations on adenosine 5ʹ monophosphate deaminase fromPlasmodium spp.
20. Phosphoglycolate phosphatase is a metabolic proofreading enzyme essential for cellular function in Plasmodium berghei
21. Metabolic proof-reading in Plasmodium berghei: essentiality of phosphoglycolate phosphatase
22. Biochemical and physiological investigations on adenosine 5’ monophosphate deaminase from Plasmodium spp.
23. Visualizing Deep Mutational Scan Data
24. Biochemical characterization and essentiality of fumarate hydratase
25. Mechanism of allostery and catalysis in P. falciparum GMP Synthetase
26. Biochemical characterization and essentiality ofPlasmodiumfumarate hydratase
27. Probing the influence of non-covalent contact networks identified by charge density analysis on the oxidoreductase BacC
28. Unexpected functional implication of a stable succinimide in the structural stability of Methanocaldococcus jannaschii glutaminase
29. Role of W181 in modulating kinetic properties ofPlasmodium falciparumhypoxanthine guanine xanthine phosphoribosyltransferase
30. Product Release Pathways in Human and Plasmodium falciparum Phosphoribosyltransferase
31. Structural and dynamical correlations in PfHGXPRT oligomers: A molecular dynamics simulation study
32. Exquisite Modulation of the Active Site of Methanocaldococcus jannaschii Adenylosuccinate Synthetase in Forward Reaction Complexes
33. Connecting Active-Site Loop Conformations and Catalysis in Triosephosphate Isomerase: Insights from a Rare Variation at Residue 96 in the Plasmodial Enzyme
34. Kinetic mechanism of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase
35. Active site coupling in Plasmodium falciparum GMP synthetase is triggered by domain rotation
36. Probing the role of highly conserved residues in triosephosphate isomerase - analysis of site specific mutants at positions 64 and 75 in thePlasmodialenzyme
37. Differential Distortion of Purine Substrates by Human andPlasmodium falciparumHypoxanthine-Guanine Phosphoribosyltransferase to Catalyse the Formation of Mononucleotides
38. Prediction of substrate specificity and preliminary kinetic characterization of the hypothetical protein PVX_123945 from Plasmodium vivax
39. Deciphering Differential Distortion of Purine Substrates by Human and Plasmodium falciparum HGPRT
40. Slow ligand-induced conformational switch increases the catalytic rate in Plasmodium falciparum hypoxanthine guanine xanthine phosphoribosyltransferase
41. A Histidine Aspartate Ionic Lock Gates the Iron Passage in Miniferritins from Mycobacterium smegmatis
42. Structural and kinetic studies on adenylosuccinate lyase fromMycobacterium smegmatisandMycobacterium tuberculosisprovide new insights on the catalytic residues of the enzyme
43. Allosteric regulation and substrate activation in cytosolic nucleotidase II fromLegionella pneumophila
44. Solution Nuclear Magnetic Resonance Structure of the GATase Subunit and Structural Basis of the Interaction between GATase and ATPPase Subunits in a two-subunit-type GMPS from Methanocaldococcus jannaschii
45. Mutational analysis of cysteine 328 and cysteine 368 at the interface of Plasmodium falciparum adenylosuccinate synthetase
46. 1H, 13C, 15N assignment and secondary structure determination of glutamine amido transferase subunit of gaunosine monophosphate synthetase from Methanocaldococcus jannaschii
47. Substrate-induced conformational changes in Plasmodium falciparum guanosine monophosphate synthetase
48. Mass spectrometric identification of an intramolecular disulfide bond in thermally inactivated triosephosphate isomerase from a thermophilic organism Methanocaldococcus jannaschii
49. Revisiting the Mechanism of the Triosephosphate Isomerase Reaction: The Role of the Fully Conserved Glutamic Acid 97 Residue
50. Mechanism of growth inhibition of intraerythrocytic stages of Plasmodium falciparum by 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR)
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