57 results on '"Augustijns P"'
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2. UNGAP best practice for improving solubility data quality of orally administered drugs
3. Effect of obesity on gastrointestinal transit, pressure and pH using a wireless motility capsule
4. Fasted and fed state human duodenal fluids: Characterization, drug solubility, and comparison to simulated fluids and with human bioavailability
5. Six years of progress in the oral biopharmaceutics area – A summary from the IMI OrBiTo project
6. Introduction to the OrBiTo decision tree to select the most appropriate in vitro methodology for release testing of solid oral dosage forms during development
7. Opening the black box: Gastric motility, as assessed by the novel vipun gastric monitoring system, is a surrogate measurement for gastric emptying
8. Evaluation of real-life dosing of oral medicines with respect to fluid and food intake in a Dutch-speaking population
9. Transport-Metabolism Interplay of Atazanavir in Rat Hepatocytes
10. Effect of Age on The Hepatocellularity Number for Wistar rats
11. Verapamil hepatic clearance in four preclinical rat models: towards activity-based scaling
12. Oral biopharmaceutics tools – Time for a new initiative – An introduction to the IMI project OrBiTo
13. Solubilizing agents in nasal formulations and their effect on ciliary beat frequency
14. Potential of amorphous microporous silica for ibuprofen controlled release
15. Interaction of HIV protease inhibitors with OATP1B1, 1B3, and 2B1
16. Postprandial Evolution in Composition and Characteristics of Human Duodenal Fluids in Different Nutritional States
17. A step further in the SATE mononucleotide prodrug approach
18. Characterization of physico-chemical properties and pharmaceutical performance of sucrose co-freeze–dried solid nanoparticulate powders of the anti-HIV agent loviride prepared by media milling
19. Effect of preservatives on ciliary beat frequency in human nasal epithelial cell culture: Single versus multiple exposure
20. Multidrug resistance-associated protein 2 (MRP2) affects hepatobiliary elimination but not the intestinal disposition of tenofovir disoproxil fumarate and its metabolites
21. Human bioavailability of propranolol from a matrix-in-cylinder system with a HPMC-Gelucire® core
22. Stable ciliary activity in human nasal epithelial cells grown in a perfusion system
23. The use of human nasal in vitro cell systems during drug discovery and development
24. Chiral capillary electrophoretic method for quantification of apomorphine
25. Effect of simulated intestinal fluid on drug permeability estimation across Caco-2 monolayers
26. Screening of Tanzanian plant extracts for their potential inhibitory effect on P‐glycoprotein mediated efflux
27. Improvement of the dissolution rate of artemisinin by means of supercritical fluid technology and solid dispersions
28. Intestinal Absorption Enhancement of the Ester Prodrug Tenofovir Disoproxil Fumarate through Modulation of the Biochemical Barrier by Defined Ester Mixtures
29. Intestinal absorption characteristics of the low solubility thiocarboxanilide UC-781
30. Influence of the composition of in-vitro azo-reducing systems on the degradation kinetics of the model compound amaranth
31. Simulated intestinal fluid as transport medium in the Caco-2 cell culture model
32. Melting behavior of pure polyethylene glycol 6000 and polyethylene glycol 6000 in solid dispersions containing diazepam or temazepam: a DSC study
33. Determination of partial solubility parameters of five benzodiazepines in individual solvents
34. New bis(SATE) prodrug of AZT 5′‐monophosphate: In vitro anti‐HIV activity, stability, and potential oral absorption
35. Synthesis and characterisation of inulin-azo hydrogels designed for colon targeting
36. Characterization of glassy itraconazole: a comparative study of its molecular mobility below Tg with that of structural analogues using MTDSC
37. Thermal characterization of the antiviral drug UC-781 and stability of its glass
38. Physical stabilisation of amorphous ketoconazole in solid dispersions with polyvinylpyrrolidone K25
39. Species-dependent and site-specific intestinal metabolism of ester prodrugs
40. In vitro transport and uptake of protohypericin and hypericin in the Caco-2 model
41. Stability prediction of amorphous benzodiazepines by calculation of the mean relaxation time constant using the Williams–Watts decay function
42. Stereoselective de-ethylation of chloroquine in rat liver microsomes
43. Inulin hydrogels as carriers for colonic drug targeting. Rheological characterization of the hydrogel formation and the hydrogel network
44. Physico-chemical characterization of solid dispersions of temazepam with polyethylene glycol 6000 and PVP K30
45. Application of the thermodynamics of mobile order and disorder to explain the solubility of temazepam in aqueous solutions of polyethylene glycol 6000
46. Use of Azo Polymers for Colon-Specific Drug Delivery
47. Determination of Chloroquine and Desethylchloroquine in Biological Samples Using Perfusion Chromatography and Fluorescence Detection
48. High Speed HPLC Determination of Bis(Pivaloyloxymethyl)-PMEA and Its Degradation Products, Mono(POM)-PMEA and PMEA
49. Transport of Artemisinin and Sodium Artesunate in Caco-2 Intestinal Epithelial Cells
50. Determination of Artesunate by Capillary Electrophoresis with Low UV Detection and Possible Applications to Analogues
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