1. Epidemiology of chronic kidney disease in older indigenous peoples of Brazil: findings from a cross-sectional survey.
- Author
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Gomes, Orlando Vieira, de Souza, Carlos Dornels Freire, Nicacio, Jandir Mendonça, do Carmo, Rodrigo Feliciano, Pereira, Vanessa Cardoso, Barral-Netto, Manoel, and da Costa Armstrong, Anderson
- Abstract
Background: Chronic kidney disease (CKD) is a prevalent disease worldwide, with increasing incidence particularly in low- and middle-income countries. Indigenous communities have poorer CKD outcomes due to limited access to healthcare. They are also experiencing a shift toward a sedentary lifestyle and urbanization-related dietary changes, increasing the risk of CKD-related risk factors. Aim: To determine the prevalence of CKD in older Brazilian indigenous and identify the main associated risk factors. Methods: This cross-sectional study analyzed demographic and clinical data of 229 older indigenous individuals aged 60 years and above in 2022–2023. CKD was defined as an estimated glomerular filtration rate < 60 mL/min/1.73 m
2 or a urinary albumin–creatinine ratio > 30 mg/g. Data were presented categorically and analyzed using the Chi-square test or Fisher's exact test. Results: The prevalence of CKD in the population was 26.6%, with higher prevalence in women and increasing with age. The prevalence of hypertension and diabetes was 67.7% and 24.0%, respectively, and these comorbidities were associated with CKD: hypertension (OR = 5.12; 95% CI 2.2–11.9) and diabetes (OR = 5.5; 95% CI 3.7–8.2). No association was found between the prevalence of CKD and obesity, dyslipidemia, cardiovascular disease, or smoking. Discussion: The study found a higher prevalence of CKD among older indigenous populations in Brazil compared to non-indigenous populations, which is exacerbated by risk factors, such as aging, hypertension, diabetes, and lifestyle changes, emphasizing the importance of early detection and intervention in these communities. Conclusion: Older persons' indigenous individuals have a high prevalence of CKD, which is correlated with factors, such as sex, age, diabetes mellitus, and hypertension. [ABSTRACT FROM AUTHOR]- Published
- 2023
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