80 results on '"Young, Joseph"'
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2. Total Synthesis of Aflastatin A.
- Author
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Evans, David A., Beiger, Jason J., Burch, Jason D., Fuller, Peter H., Glorius, Frank, Kattnig, Egmont, Thaisrivongs, David A., Trenkle, William C., Young, Joseph M., and Zhang, Jing
- Published
- 2022
- Full Text
- View/download PDF
3. Total Synthesis of Aflastatin A
- Author
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Evans, David A., Beiger, Jason J., Burch, Jason D., Fuller, Peter H., Glorius, Frank, Kattnig, Egmont, Thaisrivongs, David A., Trenkle, William C., Young, Joseph M., and Zhang, Jing
- Abstract
The total syntheses of aflastatin A and its C3–C48 degradation fragment (6a, R = H) have been accomplished. The syntheses feature several complex diastereoselective fragment couplings, including a Felkin-selective trityl-catalyzed Mukaiyama aldol reaction, a chelate-controlled aldol reaction involving soft enolization with magnesium, and an anti-Felkin-selective boron-mediated oxygenated aldol reaction. Careful comparison of the spectroscopic data for the synthetic C3–C48 degradation fragment to that reported by the isolation group revealed a structural misassignment in the lactol region of the naturally derived degradation product. Ultimately, the data reported for the naturally derived aflastatin A C3–C48 degradation lactol (6a, R = H) were attributed to its derivative lactol trideuteriomethyl ether (6c, R = CD3). Additionally, the revised absolute configurations of six stereogenic centers (C8, C9, and C28–C31) were confirmed.
- Published
- 2022
- Full Text
- View/download PDF
4. Dreams and Dust
- Author
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Young, Joseph Rex
- Abstract
An emerging body of opinion cites the Daenerys subplot in George R. R. Martin’s A Song of Ice and Fire(1996–) as a white savior narrative. This article argues against this. Martin presents his emblematic medievalist Occident as equally barbaric as his Orient, disabling the Manichean colonialist allegory some scholars perceive in his work. Although Daenerys certainly thinks like a colonialist savior, such discourse makes most sense as Bakhtinian image of a language, exhibited by Martin in concert with depictions of the intractable problems her actions cause, to mount a polemic authorial critique of colonialist literature. Support for this reading can be found elsewhere in Martin’s work, in which he frequently critiques uncritical espousals of literary tropes, and in his careful moral variegation of the peoples Daenerys conquers.
- Published
- 2022
- Full Text
- View/download PDF
5. STERNER STUF F ; SANSA STARK AND THE SYSTEM OF GOTHIC FANTASY.
- Author
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YOUNG, JOSEPH REX
- Subjects
- GAME of Thrones (TV program), MARTIN, George R. R., 1948-
- Published
- 2022
6. Outcomes of a Total Joint Arthroplasty Enhanced Recovery Program in a Community Hospital Setting.
- Author
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Adams, Curtis T., O'Connor, Casey M., Young, Joseph R., Anoushiravani, Afshin A., Doherty, Brian S., and Congiusta, Frank
- Abstract
Background: Same-day discharge (SDD) total joint arthroplasty (TJA) is increasingly popular, yet there remain concerns regarding patient safety, complication rates, and unforeseen overnight admission (failure to launch; FTL). The aim of this study is to retrospectively examine the outcomes of a large consecutive SDD-TJA series in the community hospital setting.Methods: We retrospectively reviewed 1200 consecutive SDD-TJA candidates between March 2017 and December 2019 by 5 surgeons at a community hospital. Patient demographics, perioperative data including anesthesia type, and 30-day complications were evaluated, including FTL, infection, intraoperative fracture, postoperative periprosthetic fracture or dislocation, return to operating room, and unplanned postoperative care.Results: We included 1200 SDD patients (582/618 total hip arthroplasty/total knee arthroplasty, mean age 62.1 years, 595 females, 605 males). Spinal anesthesia was more common than general anesthesia (1087 vs 113 patients). There were 85 FTLs (7.1%), of this cohort 58.8% were female, with a mean age of 62.4 years. General anesthesia increased the risk of FTL (odds ratio 2.93). Complications resulting in FTL included block-induced neuropraxia (32.1%), orthostatic hypotension (26.1%), urinary retention (19.0%), and nausea (13.1%). Sixteen patients were readmitted within 30 days (1.3%). Six patients returned to the operating room for periprosthetic fracture (4), wound dehiscence (1), and superficial surgical site infection (1).Conclusion: SDD-TJA can be safely performed at community hospitals, but general anesthesia should be avoided to decrease risk of FTL. Inpatient programs may allow young surgeons to gain experience with SDD-TJA while retaining overnight admission as a safety net for their patients.Level Of Evidence: Level III (Prognostic). [ABSTRACT FROM AUTHOR]- Published
- 2021
- Full Text
- View/download PDF
7. Impact of Experimental Protocols on the Flexural Strength Testing of Lithium Disilicate-Based Dental Glass-Ceramics
- Author
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Xu, Xinyi, Young, Joseph, and Goel, Ashutosh
- Abstract
The transition of dental ceramics and glass-ceramics (for fixed all-ceramics and metal-ceramics restorations and prostheses) from laboratory to clinic requires the materials to pass through a series of tests following the protocols and requirements discussed in the standard ISO 6872:2015. However, the literature reveals that the researchers in the dental ceramics community usually do not adhere to the ISO standard’s specifications when measuring their materials’ flexural strength, assuming that these deviations from the protocols exhibit minimal or no impact on the materials’ strength. Therefore, the present study aims to fill that gap by elucidating the impact of the following experimental protocols – (i) polishing, (ii) edge chamfering and (iii) adhesive tape on the non-tensile side – on three-point flexural strength of lithium disilicate based glass-ceramics. The result reveals that polishing increases flexural strength and tends to introduce edge or corner flaws in the specimen. Though edge chamfering of specimens did not help remove the edge defects in our study, it leads to a tighter flaw distribution, increasing the reliability of the flexural strength results. The application of adhesive tape (on the compressive side) exhibits an insignificant impact on the glass-ceramic specimens’ flexural strength. Accordingly, revisions have been suggested in the ISO 6872 standard.
- Published
- 2021
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8. Assignment of Regioisomers Using Infrared Spectroscopy: A Python Coding Exercise in Data Processing and Machine Learning
- Author
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Cahill, Samuel T., Young, Joseph E. B., Howe, Max, Clark, Ryan, Worrall, Andrew F., and Stewart, Malcolm I.
- Abstract
Machine learning is a set of tools that are increasingly used in the field of chemistry. The introduction of potential uses of machine learning to undergraduate chemistry students should help to increase their comprehension of and interest in machine learning processes and can help support them in their transition into graduate research and industrial environments that use such tools. Herein we present an exercise aimed at introducing machine learning alongside improving students’ general Python coding abilities. The exercise aims to identify the regioisomerism of disubstituted benzene systems solely from infrared spectra, a simple and ubiquitous undergraduate technique. The exercise culminates in students collecting their own spectra of compounds with unknown regioisomerism and predicting the results, allowing them to take ownership of their results and creating a larger database of information to draw upon for machine learning in the future.
- Published
- 2024
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- View/download PDF
9. Useful Little Men: George R. R. Martin's Dwarfs as Grotesque Realists.
- Author
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Young, Joseph Rex
- Subjects
DWARVES (Mythological characters) in literature ,GROTESQUE in literature ,LITERARY realism ,VIOLENCE in literature ,HEALING in literature ,POWER (Social sciences) in literature - Abstract
The article explores dwarfs as representation of the elements of grotesque realism in George R.R. Martin's "A Song of Ice and Fire." Topics discussed are aspects of violence or degradation as preconditions for recovery and healing, apex of Targaryen power and artificiality of hierarchies, instances of Clutean thinning such as Rhaenyra's capture of the King's Landing, and pattern of death and rebirth implied by Bakhtinian grotesquery.
- Published
- 2020
10. Initiation of the ABCD3-I algorithm for expediated evaluation of transient ischemic attack patients in an emergency department.
- Author
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Dahlquist, Robert T, Young, Joseph M, Reyner, Karina, Farzad, Ali, Moleno, Richard B, Gandham, Gautami, Ho, Amy F, and Wang, Hao
- Abstract
Background: The use of ABCD3-I score for Transient ischemic attack (TIA) evaluation has not been widely investigated in the ED. We aim to determine the performance and cost-effectiveness of an ABCD3-I based pathway for expedited evaluation of TIA patients in the ED.Methods: We conducted a single-center, pre- and post-intervention study among ED patients with possible TIA. Accrual occurred for seven months before (Oct. 2016-April 2017) and after (Oct. 2017-April 2018) implementing the ABCD3-I algorithm with a five-month wash-in period (May-Sept. 2017). Total ED length of stay (LOS), admissions to the hospital, healthcare cost, and 90-day ED returns with subsequent stroke were analyzed and compared.Results: Pre-implementation and post-implementation cohorts included 143 and 118 patients respectively. A total of 132 (92%) patients were admitted to the hospital in the pre-implementation cohort in comparison to 28 (24%) patients admitted in the post-implementation cohort (p < 0.001) with similar 90-day post-discharge stroke occurrence (2 in pre-implementation versus 1 in post-implementation groups, p > 0.05). The mean ABCD2 scores were 4.5 (1.4) in pre- and 4.1 (1.3) in post-implementation cohorts (p = 0.01). The mean ABCD3-I scores were 4.5 (1.8) in post-implementation cohorts. Total ED LOS was 310 min (201, 420) in pre- and 275 min (222, 342) in post-implementation cohorts (p > 0.05). Utilization of the ABCD3-I algorithm saved an average of over 40% of total healthcare cost per patient in the post-implementation cohort.Conclusions: The initiation of an ABCD3-I based pathway for TIA evaluation in the ED significantly decreased hospital admissions and cost with similar 90-day neurological outcomes. [ABSTRACT FROM AUTHOR]- Published
- 2020
- Full Text
- View/download PDF
11. Soil carbon sequestration in bermudagrass golf course fairways in Lubbock, Texas.
- Author
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Gautam, Prativa, Young, Joseph R., Sapkota, Manish, Longing, Scott, and Weindorf, David C.
- Abstract
Turfgrasses benefit the environment through conversion of CO2 into stable C stored in soils. Limited research on the sequestration potential of bermudagrass (Cynodon spp.) has been conducted in semiarid climates. The objective of this study was to evaluate soil physiochemical properties of golf courses in Lubbock, TX, to determine C sequestration potential and longevity. Soil was obtained from fairways of five golf courses ranging in age from 13 to 93 yr. Shallow (0–7.5 cm) and deeper (7.5–15 cm) soil depths were tested for soil pH, electrical conductivity, soil organic matter, soil organic C (SOC), inorganic C, total N, inorganic N, and texture. After ANOVA and mean separation, principal component analysis (PCA) was used to group golf courses by soil depth or age. Soil organic matter and SOC decreased with depth, but the rate of SOC accumulation (0.22 Mg C ha−1 yr−1) was lower when compared with previous studies. Maximal C (35.1 and 23.7 Mg C ha−1 in the upper and lower depths) was consistent with previous studies, indicating that C accumulated for a longer period of time. The PCA explained 52.7% of variability in soil physiochemical properties on two axes, but PCA more effectively differentiated soil sampling depth than golf course age. High variability in data among fairways at a single golf course likely resulted in limited grouping capabilities. Including a broader regional representation of golf courses or sampling golf courses between 40 and 70 yr to quantify soils near maximal accumulation would strengthen future studies. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
12. Oral health implications in total hip and knee arthroplasty patients: A review
- Author
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Young, Joseph R., Bannon, Annika L., Anoushiravani, Afshin A., Posner, Andrew D., Adams, Curtis T., and DiCaprio, Matthew R.
- Abstract
Over the past two decades, oral health has emerged as a health care priority. Historically, patients greater than 65 years of age, the economically disadvantaged, members of racial or ethnic minority groups, or the disabled or home bound have experienced significant barriers to routine dental care. The connection between oral health care and periprosthetic joint infections (PJI) continues to be of importance to the orthopedic surgeon, as such infections are significantly morbid and costly. This review aims to introduce the importance of oral health as a small but crucial portion of an arthroplasty patient's overall perioperative management.
- Published
- 2021
- Full Text
- View/download PDF
13. The Fragmentation and Recovery of Zdzisław Beksiński
- Author
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Young, Joseph Rex
- Abstract
Abstract:This article uses literary theory to propose an explanation for the range of responses to the art of Zdzisław Beksiński, whose work tends to provoke either hyperbolic disgust or intense awe. Beksiński's decision never to title his paintings necessitates ekphrasis, the translation of visual images into prose, which in the case of Beksiński's images breaks down due to the impossibility of describing his figures in plain speech. An ekphrasis of these images thus pushes the viewer into the second stage of Thomas Weiskel's three-stage model of Romantic transcendence—deprived of the ability to speak and searching for a way to recover it. Neither of Weiskel's codified approaches to this crisis—the metaphorical or the metonymical—are effective solutions to this problem, marooning viewers in Weiskel's second stage with no chance of reaching the third stage, where they would be reconciled with the contents of their world.The viewer of a Beksiński painting must therefore contend with what David Sandner calls an "open" response to the sublime, accepting the sublime as an ongoing feature of their world. One of Sandner's codified open responses, fragmentation, precisely describes the response of those who regard Beksiński's art as fearsome or disgusting, forcing the viewer into an encounter with something they dislike. The other, dispossession, closely describes the sense of transcendent power other viewers ascribe to these images. The process of Sandnerian dispossession with regard to Beksiński's paintings is elucidated by comparing it to a similar process in neo-Romantic theory, J. R. R. Tolkien's concept of Recovery, the highlighting of the natural and human via their contrast with purpose-built manifestations of the supernatural and inhuman. Various of Beksiński's paintings yield to such analysis, as studies of humanitas celebrated in contrast to preternatural inhumanity. The key to the power of these images is their ability to show the viewer something of themselves.
- Published
- 2020
14. Soil carbon sequestration in bermudagrass golf course fairways in Lubbock, Texas
- Author
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Gautam, Prativa, Young, Joseph R., Sapkota, Manish, Longing, Scott, and Weindorf, David C.
- Abstract
Turfgrasses benefit the environment through conversion of CO2into stable C stored in soils. Limited research on the sequestration potential of bermudagrass (Cynodonspp.) has been conducted in semiarid climates. The objective of this study was to evaluate soil physiochemical properties of golf courses in Lubbock, TX, to determine C sequestration potential and longevity. Soil was obtained from fairways of five golf courses ranging in age from 13 to 93 yr. Shallow (0–7.5 cm) and deeper (7.5–15 cm) soil depths were tested for soil pH, electrical conductivity, soil organic matter, soil organic C (SOC), inorganic C, total N, inorganic N, and texture. After ANOVA and mean separation, principal component analysis (PCA) was used to group golf courses by soil depth or age. Soil organic matter and SOC decreased with depth, but the rate of SOC accumulation (0.22 Mg C ha−1yr−1) was lower when compared with previous studies. Maximal C (35.1 and 23.7 Mg C ha−1in the upper and lower depths) was consistent with previous studies, indicating that C accumulated for a longer period of time. The PCA explained 52.7% of variability in soil physiochemical properties on two axes, but PCA more effectively differentiated soil sampling depth than golf course age. High variability in data among fairways at a single golf course likely resulted in limited grouping capabilities. Including a broader regional representation of golf courses or sampling golf courses between 40 and 70 yr to quantify soils near maximal accumulation would strengthen future studies.
- Published
- 2020
- Full Text
- View/download PDF
15. Effects of Cultivation Practices and Products on Bermudagrass Fairways in a Semiarid Region
- Author
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Li, Li, Young, Joseph, and Deb, Sanjit
- Abstract
High evapotranspirational demand combined with poor quality irrigation water increases salinity concerns in semiarid regions. Accumulated salts in the root zone may negatively affect bermudagrass (Cynodonspp.) growth and quality. The objective of this study was to examine the effectiveness of cultivation practices combined with products to enhance fairway conditions without applying leaching water levels. Two golf courses in Lubbock, TX, were selected for this research. Cultivation practices, including noncultivated control, core aerification, and slicing, were conducted in mid‐June of 2015 and 2016. Nine products recommended to enhance water movement or to disassociate sodium were applied within each cultivation treatment at label rates. Soil pH and electrical conductivity (EC) were determined from samples obtained in June, August, and October each year. Volumetric water content, visual turf quality, digital image analysis, normalized difference vegetation index, and ratio vegetation index were assessed from June to October in 2015 and 2016. Soil EC fluctuated with rainfall events. However, no treatment reduced soil EC. Gypsum‐based products increased soil EC but reduced pH at the conclusion of the research. Core aerification reduced aboveground parameters at Golf Course A because aerified holes remained visible throughout summer, whereas slicing and core aerification improved turf quality and ratio vegetation index at Golf Course B. These results emphasize the need to test irrigation water for the salinity hazard before implementing management strategies and the importance of leaching by rainfall or additional irrigation. Lastly, high surface disruption cultivation practices may inhibit bermudagrass recovery on higher clay content soils. Core IdeasRainfall and high ET fluctuated soil EC of bermudagrass golf fairways.Gypsum products increased soil EC and reduced soil pH after 2 yr of applications.Bermudagrass recovery from core aerification was slowed with higher clay content.Cultivation practices improved parameters on high sand content soil after recovery. Rainfall and high ET fluctuated soil EC of bermudagrass golf fairways. Gypsum products increased soil EC and reduced soil pH after 2 yr of applications. Bermudagrass recovery from core aerification was slowed with higher clay content. Cultivation practices improved parameters on high sand content soil after recovery.
- Published
- 2019
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16. HARRY POTTER AND THE OTHER: RACE, JUSTICE, AND DIFFERENCE IN THE WIZARDING WORLD/OPEN AT THE CLOSE: LITERARY ESSAYS ON HARRY POTTER.
- Author
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Young, Joseph Rex
- Subjects
NONFICTION - Published
- 2022
17. Spiropiperidine Sultam and Lactam Templates: Diastereoselective Overman Rearrangement and Metathesis followed by NH Arylation.
- Author
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Martinez-Alsina, Luis A., Murray, John C., Buzon, Leanne M., Bundesmann, Mark W., Young, Joseph M., and O'Neill, Brian T.
- Published
- 2017
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18. The Discovery of a Novel Phosphodiesterase (PDE) 4B-Preferring Radioligand for Positron Emission Tomography (PET) Imaging.
- Author
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Lei Zhang, Laigao Chen, Beck, Elizabeth M., Chappie, Thomas A., Coelho, Richard V., Doran, Shawn D., Kuo-Hsien Fan, Helal, Christopher J., Humphrey, John M., Hughes, Zoe, Kuszpit, Kyle, Lachapelle, Erik A., Lazzaro, John T., Chewah Lee, Mather, Robert J., Patel, Nandini C., Skaddan, Marc B., Sciabola, Simone, Verhoest, Patrick R., and Young, Joseph M.
- Published
- 2017
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- View/download PDF
19. ENDOSCOPIC ULTRASOUND GUIDED-GASTROENTEROSTOMY, SELF-EXPANDING METAL STENT PLACEMENT, AND SURGICAL GASTROJEJUNOSTOMY FOR THE TREATMENT OF MALIGNANT GASTRIC OUTLET OBSTRUCTION.
- Author
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Hussain, Maryam R., Ali, Faisal S., Soin, Sarthak, Aziz, Muhammad, Reymunde Duran, Diego A., Glombicki, Stephen E., Young, Joseph, Khan, Zubair, Rashtak, Shahrooz, Wadhwa, Vaibhav, Ramireddy, Srinivas, Guha, Sushovan, DaVee, Tomas, and Thosani, Nirav
- Published
- 2022
- Full Text
- View/download PDF
20. Golf Ball Mark Severity and Recovery as Affected by Mowing Height, Rolling Frequency, Foot Traffic, and Moisture.
- Author
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Young, Joseph, Richardson, Mike, and Karcher, Douglas
- Abstract
Putting greens experience stress from golf balls striking the surface, maintenance equipment, and foot traffic. Improved creeping bentgrass (Agrostis stolonifera L.) cultivars, sand-based root zones, and skilled superintendents maintain plant health while providing firmer conditions. Many researchers have studied effects of compaction and wear on putting greens, but few have determined the effect of these stresses on ball marks. The objective of this research was to evaluate ball mark severity and recovery of creeping bentgrass under different mowing heights (2.5, 3.2, and 4.0 mm), rolling frequencies (0, 3, or 6 d wk
-1 ), and foot traffic using digital image analysis. Digital images of golf balls placed in the depression were used to calculate ball mark depth, and a cover analysis was conducted to model ball mark injury area using a one phase decay model to determine theoretical maximum injury, slope, and days to 50% recovery. Soil moisture content was positively correlated with ball mark depth, but common stresses rarely altered ball mark depth. The mean theoretical maximum ball mark injury was 377 mm2 greater for daily rolled treatments in 2010 compared to non-rolled treatments. The slope of recovery rarely changed among treatments suggesting that theoretical maximum ball mark injury area has a greater effect on recovery. Lastly, combining the lowest mowing height or daily rolling and foot traffic slowed the time ball marks took to reach 50% recovery. This research demonstrates the effects common management practices and soil moisture have on the severity and recovery of ball marks during environmental stress. [ABSTRACT FROM AUTHOR]- Published
- 2017
- Full Text
- View/download PDF
21. "ENOUGH ABOUT WHORES": SEXUAL CHARACTERIZATION IN A SONG OF ICE AND FIRE.
- Author
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YOUNG, JOSEPH
- Subjects
LITERARY theory ,MEDIEVAL & modern Latin literature - Abstract
The article analyzes sexual characterization in George R.R. Martin's A Song of Ice and Fire series. It also describes literary theory to demonstrate the extent and purpose of the theme poet Isaac Rosenberg identifies in the behavior of any character in Martin's world of gritty medievaliam beyond reproach.
- Published
- 2017
22. Layout Optimization of a Repair Facility Using Discrete Event Simulation.
- Author
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Prajapat, Neha, Waller, Tony, Young, Joseph, and Tiwari, Ashutosh
- Abstract
Technological advancements in the field of simulation have enabled production managers to model and simulate their facilities under various scenarios, in order to optimize system performance. In particular the reconfiguration of factory layouts can be time consuming and expensive; Discrete Event Simulation (DES) can be used to model and assess various scenarios to assist production managers with layout planning. Significant benefits can be achieved through the use of DES for factory layout optimization including: decreased lead times, reduced manufacturing costs, efficient materials handling and increased profit. This paper presents the development of a DES model in WITNESS for the analysis and factory layout optimization of a repair facility. The aim of the model is to allow decision makers to assess various layouts and configurations with a view to optimize production. The model has been built with a link to an Excel spreadsheet to enable data input and the visualization of Key Performance Indicators (KPIs). Specific functions have been built into the simulation model to set and save new layouts within Excel to facilitate layout optimization. The model will be used to optimize the factory configuration. [ABSTRACT FROM AUTHOR]
- Published
- 2016
- Full Text
- View/download PDF
23. Spray retention on whole plants: modelling, simulations and experiments.
- Author
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Dorr, Gary J., Forster, W. Alison, Mayo, Lisa C., McCue, Scott W., Kempthorne, Daryl M., Hanan, Jim, Turner, Ian W., Belward, John A., Young, Joseph, and Zabkiewicz, Jerzy A.
- Subjects
AGRICULTURAL chemistry ,COTTON ,PLANT species ,COMPUTER simulation ,PREDICTION models ,SPRAY nozzles - Abstract
Retention of sprays on plants is a critical component influencing the effectiveness of agrichemical applications. Previous simulations of s pray retention by plants gave poor agreement for hard-to-wet species when compared with actual measured retention. A new model is developed here that accounts for: species wettability, impaction angle, droplet bounce, partial retention on shatter, a variable time to shatter, and the number of daughter droplets produced. The aim of this study was to compare predictions from the new model with data obtained by spraying five mixtures via five nozzles onto easy-to-wet cotton ( Gossypium hirsutum L.), and hard-to-wet wheat ( Triticum aestivum L.) and fat hen ( Chenopodium album L.). The new model correctly predicts retention to be highest on cotton and lowest on wheat. The trend in both measured data and the model predictions is for retention to decrease with increasing droplet size, on all three plant species. Formulation is correctly predicted to have little influence on retention by easy-to-wet cotton plants and to enhance retention by the harder-to-wet wheat and fat hen plants. The parameters that describe partial retention on shatter and variable time to shatter have a substantial influence on retention, as they affect primary or secondary droplet capture. A better understanding of the kinetic energy effects and the interactions between the formulation and the leaf surface are needed to refine their input values. [ABSTRACT FROM AUTHOR]
- Published
- 2016
- Full Text
- View/download PDF
24. Potato Peels and Their Bioactive Glycoalkaloids and Phenolic Compounds Inhibit the Growth of Pathogenic Trichomonads
- Author
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Friedman, Mendel, Huang, Vincent, Quiambao, Quincel, Noritake, Sabrina, Liu, Jenny, Kwon, Ohkun, Chintalapati, Sirisha, Young, Joseph, Levin, Carol E., Tam, Christina, Cheng, Luisa W., and Land, Kirkwood M.
- Abstract
Potato peel, a waste product of the potato processing industry, is high in bioactive compounds. We investigated the in vitro antitrichomonad activity of potato peel powders prepared from commercial Russet, red, purple, and fingerling varieties as well as several known potato components, alkaloids and phenolic compounds, against three pathogenic strains of trichomonads. Trichomonas vaginalisis a sexually transmitted protozoan parasite that causes the human disease trichomoniasis. Two distinct strains of the related Tritrichomonas fetusinfect cattle and cats. The glycoalkaloids α-chaconine and α-solanine were highly active against all parasite lines, while their common aglycone solanidine was only mildly inhibitory. α-Solanine was several times more active than α-chaconine. The phenolic compounds caffeic and chlorogenic acids and quercetin were mildly active against the parasites. Most of the potato peel samples were at least somewhat active against all three trichomonad species, but their activities were wide-ranging and did not correspond to their glycoalkaloid and phenolic content determined by HPLC. The two Russet samples were the most active against all three parasites. The purple potato peel sample was highly active against bovine and mostly inactive against feline trichomonads. None of the test substances were inhibitory toward several normal microflora species, suggesting the potential use of the peels for targeted therapeutic treatments against trichomonads.
- Published
- 2018
- Full Text
- View/download PDF
25. Selective Access to Heterocyclic Sulfonamides and Sulfonyl Fluorides via a Parallel Medicinal Chemistry Enabled Method.
- Author
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Tucker, Joseph W., Chenard, Lois, and Young, Joseph M.
- Published
- 2015
- Full Text
- View/download PDF
26. Creeping Bentgrass Putting Green Response to Combined Mowing, Rolling, and Foot Traffic under Environmental Stress.
- Author
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Young, Joseph, Richardson, Mike, and Karcher, Doug
- Abstract
Creeping bentgrass (Agrostis stolonifera L.) putting greens in the transition zone experience high levels of environmental stress during summer months. The interaction of common management practices combined with foot traffic can exacerbate environmental stress. The objective of this study was to determine the effect of management practices combined with foot traffic during high environmental stress in the transition zone. Creeping bentgrass cultivars, SR 1020 and Penn G2, were managed with various mowing heights (2.5, 3.2, or 4.0 mm), rolling frequencies (0, 3, or 6 d per week), and foot traffic. As environmental stress became prominent during summer months, bentgrass maintained at the lowest mowing heights exhibited poorer turf quality, coverage, and wear tolerance compared to the highest mowing height. SR 1020 quality was reduced below acceptable levels in July when mowed at the lowest mowing height in 2011 and 2012. Penn G2 maintained acceptable quality at all mowing heights in 2011, but severe heat and drought stress reduced turf quality regardless of mowing height in 2012. Daily rolling significantly increased wear on both cultivars during high environmental stress that resulted in decreased turf quality and coverage compared to the nonrolled treatments. The combination of wear from mechanical stress and foot traffic increased wear injury on both cultivars. Under reduced daylengths and optimal air temperatures in September of each year, all response variables improved to similar levels. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
27. Golf Ball Mark Severity and Recovery as Affected by Mowing Height, Rolling Frequency, Foot Traffic, and Moisture
- Author
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Young, Joseph, Richardson, Mike, and Karcher, Douglas
- Abstract
Digital image analysis methods to evaluate putting green ball mark severity and recovery.Firmer surfaces from dry conditions or lightweight rolling increased maximum ball mark injury area.Rate of recovery was similar for all treatments, but increased wear increased time to 50% recovery.Demonstrates positive attributes of dispersing foot and equipment traffic throughout the green. Putting greens experience stress from golf balls striking the surface, maintenance equipment, and foot traffic. Improved creeping bentgrass (Agrostis stoloniferaL.) cultivars, sand‐based root zones, and skilled superintendents maintain plant health while providing firmer conditions. Many researchers have studied effects of compaction and wear on putting greens, but few have determined the effect of these stresses on ball marks. The objective of this research was to evaluate ball mark severity and recovery of creeping bentgrass under different mowing heights (2.5, 3.2, and 4.0 mm), rolling frequencies (0, 3, or 6 d wk−1), and foot traffic using digital image analysis. Digital images of golf balls placed in the depression were used to calculate ball mark depth, and a cover analysis was conducted to model ball mark injury area using a one phase decay model to determine theoretical maximum injury, slope, and days to 50% recovery. Soil moisture content was positively correlated with ball mark depth, but common stresses rarely altered ball mark depth. The mean theoretical maximum ball mark injury was 377 mm2greater for daily rolled treatments in 2010 compared to non‐rolled treatments. The slope of recovery rarely changed among treatments suggesting that theoretical maximum ball mark injury area has a greater effect on recovery. Lastly, combining the lowest mowing height or daily rolling and foot traffic slowed the time ball marks took to reach 50% recovery. This research demonstrates the effects common management practices and soil moisture have on the severity and recovery of ball marks during environmental stress.
- Published
- 2017
- Full Text
- View/download PDF
28. The Synthesis of Alkyl and (Hetero)aryl Sulfonamides From Sulfamoyl Inner Salts.
- Author
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Young, Joseph M., Lee, Aisha G., Chandrasekaran, Ramalakshmi Y., and Tucker, Joseph W.
- Published
- 2015
- Full Text
- View/download PDF
29. Discovery of a Series of Efficient,Centrally EfficaciousBACE1 Inhibitors through Structure-Based Drug Design.
- Author
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Butler, Christopher R., Brodney, Michael A., Beck, Elizabeth M., Barreiro, Gabriela, Nolan, Charles E., Feng Pan, Vajdos, Felix, Parris, Kevin, Varghese, Alison H., Helal, Christopher J., Lira, Ricardo, Doran, Shawn D., Riddell, David R., Buzon, Leanne M., Dutra, Jason K., Martinez-Alsina, Luis A., Ogilvie, Kevin, Murray, John C., Young, Joseph M., and Atchison, Kevin
- Published
- 2015
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30. Recent Intensification (2004–2020) of Permafrost Mass‐Wasting in the Central Mackenzie Valley Foothills Is a Legacy of Past Forest Fire Disturbances
- Author
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Young, Joseph M., Alvarez, Alejandro, Sluijs, Jurjen, Kokelj, Steven V., Rudy, Ashley, McPhee, Alex, Stoker, Benjamin J., Margold, Martin, and Froese, Duane
- Abstract
The effects of recent climate change are accelerating permafrost thaw, including ice‐rich landscapes of the western Canadian Arctic. However, regional drivers of permafrost slope failure in hillslopes with warm, thin permafrost remain poorly understood. Repeat satellite imagery (1984–2020) indicates rapid increases in retrogressive thaw slumps (RTSs) and deep‐seated permafrost landslides (DSPLs) since 2004, indicating a change in slope stability thresholds in an area that otherwise appeared thaw stable. The widespread occurrence of DSPL represents a contrasting geomorphic response to the RTS‐dominated ice‐rich permafrost landscapes. In this study area, RTS and DSPL occur predominantly in areas that were burned by forest fires in the 1990s, indicating a legacy thermal disturbance that preconditioned permafrost hillslopes for failure. The relations between historic fires and the later development of widespread permafrost slope failures represent an outstanding example of the complex interactions between inherited landscape sensitivity in ice‐rich terrain and ongoing climate change. We characterize the type and nature of permafrost slope failures in the central Mackenzie Valley, NWT and find hillslope failures have increased rapidly over the past ∼15 years. This growth occurred in conjunction with increasing air temperatures and summer precipitation but the distribution of permafrost slope failures in this area is largely constrained by forest fire extents that affected the area in the 1990s. These fires have led to increased landscape sensitivity of this ice‐rich terrain through their impacts on ground temperatures. Recent increases in permafrost mass‐wasting frequency (278%) and magnitude (602%) reveal a permafrost landscape in geomorphic transitionMore than 80% of failures occur in areas burned in the 1990sCompounding effects of legacy thermal disturbance and climate drivers of thaw likely to increase slope instability of warm permafrost Recent increases in permafrost mass‐wasting frequency (278%) and magnitude (602%) reveal a permafrost landscape in geomorphic transition More than 80% of failures occur in areas burned in the 1990s Compounding effects of legacy thermal disturbance and climate drivers of thaw likely to increase slope instability of warm permafrost
- Published
- 2022
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31. Dual-Energy Head CT Enables Accurate Distinction of Intraparenchymal Hemorrhage from Calcification in Emergency Department Patients
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Hu, Ranliang, Besheli, Laleh Daftari, Young, Joseph, Wu, Markus, Pomerantz, Stuart, Lev, Michael H., and Gupta, Rajiv
- Abstract
Dual-energy CT can distinguish intraparenchymal hemorrhage from calcification rapidly and with very high accuracy in emergency department patients and can be especially useful in problem-solving complex cases that are difficult to interpret based on conventional CT findings.
- Published
- 2016
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32. Creeping Bentgrass Putting Green Response to Combined Mowing, Rolling, and Foot Traffic Under Environmental Stress
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Young, Joseph, Richardson, Mike, and Karcher, Doug
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Creeping bentgrass (Agrostis stoloniferaL.) putting greens in the transition zone experience high levels of environmental stress during summer months. The interaction of common management practices combined with foot traffic can exacerbate environmental stress. The objective of this study was to determine the effect of management practices combined with foot traffic during high environmental stress in the transition zone. Creeping bentgrass cultivars, SR 1020 and Penn G2, were managed with various mowing heights (2.5, 3.2, or 4.0 mm), rolling frequencies (0, 3, or 6 d per week), and foot traffic. As environmental stress became prominent during summer months, bentgrass maintained at the lowest mowing heights exhibited poorer turf quality, coverage, and wear tolerance compared to the highest mowing height. SR 1020 quality was reduced below acceptable levels in July when mowed at the lowest mowing height in 2011 and 2012. Penn G2 maintained acceptable quality at all mowing heights in 2011, but severe heat and drought stress reduced turf quality regardless of mowing height in 2012. Daily rolling significantly increased wear on both cultivars during high environmental stress that resulted in decreased turf quality and coverage compared to the non‐rolled treatments. The combination of wear from mechanical stress and foot traffic increased wear injury on both cultivars. Under reduced daylengths and optimal air temperatures in September of each year, all response variables improved to similar levels.
- Published
- 2015
- Full Text
- View/download PDF
33. Survival of the Fittest: Why Terrorist Groups Endure.
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Young, Joseph K. and Dugan, Laura
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TERRORIST organizations ,TERRORISM ,POLITICAL violence ,TERRORISTS ,TRANSNATIONAL crime - Abstract
Why do terrorist groups endure? This question is relevant to scholars and policy makers alike. In the past, this issue has not been addressed in a systematic fashion. Recent work investigates this question using data on transnational groups and finds that factors associated with the home country can influence the group's endurance. Applying the theory of outbidding to terrorist group survival, we argue that strategic competition among groups predicts group duration. Using the Global Terrorism Database, we develop a dataset using the terrorist group as the unit of analysis to model the duration of group activity and thus include the largest sample of groups yet. Controlling for previous explanations of both group duration and terrorism, we find a robust effect for the impact that group competition has on terrorist group survival. [ABSTRACT FROM AUTHOR]
- Published
- 2014
34. ARTEMIS AT RAGNAROK: E.R. EDDISON'S QUEEN ANTIOPE.
- Author
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YOUNG, JOSEPH
- Subjects
MYTHOLOGY in literature ,TRILOGIES (Literature) ,ETHICS in literature - Abstract
A literary criticism of the Zimiamvian Trilogy by E. R. Eddison is presented. Particular focus is given to the deep philosophical and spiritual foundation at the base of the trilogy. It outlines the characters, with an emphasis on the main character Queen Antiope from "Mistress of Mistresses," the first volume of the series. It examines Eddison's web of mythological and literary allusions. An overview of the story is provided.
- Published
- 2014
35. Conjugated Polymer Assemblies on Carbon Nanotubes.
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Liu, Jianhua, Moo-Young, Joseph, McInnis, Matthew, Pasquinelli, Melissa A., and Zhai, Lei
- Published
- 2014
- Full Text
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36. Vitamin D Therapy in Individuals With Prehypertension or Hypertension
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Arora, Pankaj, Song, Yanna, Dusek, Jeffery, Plotnikoff, Gregory, Sabatine, Marc S., Cheng, Susan, Valcour, Andre, Swales, Heather, Taylor, Beth, Carney, Erin, Guanaga, Derek, Young, Joseph R., Karol, Courtney, Torre, Michael, Azzahir, Atum, Strachan, Semerit M., O’Neill, Dillon C., Wolf, Myles, Harrell, Frank, Newton-Cheh, Christopher, and Wang, Thomas J.
- Abstract
Supplemental Digital Content is available in the text.
- Published
- 2015
- Full Text
- View/download PDF
37. Stereoselective Synthesis of Spiropiperidines as BACE-1 Aspartyl Protease Inhibitors via Late Stage N-Arylation of a 1,8-Diazaspiro[4.5]dec-3-en-2-one Pharmacophore.
- Author
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Che-Wah Lee, Lira, Ricardo, Dutra, Jason, Ogilvie, Kevin, O'Neill, Brian T., Brodney, Michael, Helal, Christopher, Young, Joseph, Lachapelle, Erik, Sakya, Subas, and Murray, John C.
- Published
- 2013
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- View/download PDF
38. Telescoped Flow Processfor the Syntheses of N-Aryl Pyrazoles.
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Li, Bryan, Widlicka, Daniel, Boucher, Steven, Hayward, Cheryl, Lucas, John, Murray, John C., O’Neil, Brian T., Pfisterer, David, Samp, Lacey, VanAlsten, John, Xiang, Yanqiao, and Young, Joseph
- Published
- 2012
- Full Text
- View/download PDF
39. Radiation Dose Limits and Liver Toxicities Resulting from Multiple Yttrium-90 Radioembolization Treatments for Hepatocellular Carcinoma.
- Author
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Young, Joseph Y., Rhee, Thomas K., Atassi, Bassel, Gates, Vanessa L., Kulik, Laura, Mulcahy, Mary F., Larson, Andrew C., Ryu, Robert K., Sato, Kent T., Lewandowski, Robert J., Omary, Reed A., and Salem, Riad
- Subjects
RADIOTHERAPY ,RADIATION doses ,LIVER diseases ,CANCER - Abstract
Purpose: To assess the relationship between cumulative hepatic lobar radiation dose and liver toxicities in patients with hepatocellular carcinoma (HCC) treated with multiple sessions of yttrium-90 radioembolization. Materials and Methods: Forty-one patients with HCC (age range, 46–82 years) underwent radioembolization with
90 Y. Patients were classified according to the Okuda scoring system. All patients received single liver lobar treatments on two or more occasions according to standard clinical90 Y embolization protocol. Cumulative radiation dose to each liver lobe was measured and patients were followed to assess liver toxicities. Statistical analysis was performed with the Student t test and Kaplan-Meier analysis. Results: Patients with Okuda stage I disease received more treatments than those with Okuda stage II disease (mean, 2.65 vs 2.24; P < .05). For average cumulative radiation dose, patients with Okuda stage I disease received 247 Gy (range, 88–482 Gy) and those with Okuda stage II disease received 198 Gy (range, 51–361 Gy; P < .05). A total of 13 toxicities occurred in seven patients (16%). Patients with Okuda stage I disease were given a greater cumulative dose than patients with Okuda stage II disease before worsening of liver function: 390 Gy versus 196 Gy (P < .005). For patients with Okuda stage I disease, a higher cumulative radiation dose was associated with occurrence of one or more toxicities: 222 Gy (no toxicities) versus 390 Gy (≥1 toxicity; P < .005). No correlation between cumulative radiation dose and liver toxicities existed in patients with Okuda stage II disease. The maximum tolerated dose was between 222 and 390 Gy. Median survival times were 660 and 431 days for patients with Okuda stage I and stage II disease, respectively. Conclusions: Patients with HCC can tolerate high cumulative radiation doses with90 Y therapy. Compared with patients with Okuda stage II disease, patients with Okuda stage I disease tolerate a higher cumulative radiation dose without liver toxicity, but liver toxicities increase with increasing cumulative radiation doses. [Copyright &y& Elsevier]- Published
- 2007
- Full Text
- View/download PDF
40. Effect of Transcatheter Arterial Embolization on Levels of Hypoxia-inducible Factor-1α in Rabbit VX2 Liver Tumors.
- Author
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Rhee, Thomas K., Young, Joseph Y., Larson, Andrew C., Haines, G. Kenneth, Sato, Kent T., Salem, Riad, Mulcahy, Mary F., Kulik, Laura M., Paunesku, Tatjana, Woloschak, Gayle E., and Omary, Reed A.
- Subjects
LIVER tumors ,LABORATORY animals ,MAGNETIC resonance imaging ,CROSS-sectional imaging - Abstract
Purpose: To test the hypothesis that transcatheter arterial embolization (TAE) of VX2 rabbit liver tumors increases the expression of hypoxia-inducible factor-1α (HIF-1α), a transcription factor that regulates the expression of pro-angiogenic genes. Materials and Methods: VX2 tumors were implanted in the livers of eight New Zealand white rabbits. Once tumor growth was seen at T2-weighted turbo spin-echo magnetic resonance (MR) imaging, four of the eight rabbits underwent TAE with 45–150-μm polyvinyl alcohol particles. The remaining four rabbits served as non-TAE controls. The TAE end point was stasis of antegrade blood flow. All rabbits were sacrificed for tumor harvest 2 hours after TAE. Tumor tissue and corresponding normal liver tissue in each rabbit liver were stained with anti-human HIF-1α monoclonal antibody and reviewed with light microscopy. Percentages of stained viable tumor and normal liver cells were compared by using the Mann-Whitney U test (α = 0.05). Results: In eight rabbits with 24 discrete liver tumors, the mean percentage (±standard deviation) of positive HIF-1α–stained cells in the TAE group was greater than that in the control group (19% ± 7.0 vs 12% ± 8.0, respectively) (P = .05). Normal liver tissue in both the TAE and control groups showed no HIF-1α staining. Conclusion: Although HIF-1α is not expressed in normal rabbit liver parenchyma—even after TAE—HIF-1α expression is present in implanted VX2 rabbit liver tumors and significantly increased in lesions that have undergone embolization. [Copyright &y& Elsevier]
- Published
- 2007
- Full Text
- View/download PDF
41. Interactions of Liposome Carriers with Infectious Fungal Hyphae Reveals the Role of β-Glucans
- Author
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Chavan, Neelam L., Young, Joseph K., Drezek, Rebekah A., Lewis, Russell, and Bikram, Malavosklish
- Abstract
Relatively little is known about how liposomal formulations modulate drug delivery to fungal pathogens. We compared patterns of hyphal cell wall binding for empty rhodmine-labeled liposomes and the clinically available amphotericin B-containing liposomal formulation (AmBisome) in Aspergillus fumigatusand Candida albicans.Following 0.5 h of coincubation with A. fumigatus, empty liposomes concentrated primarily in fungal septae along at the surface of the cell wall, suggesting that liposome uptake is concentrated in areas of the cell wall where linear glucan is exposed on the cell surface, which was confirmed by aniline blue staining. Consistent with this hypothesis, pretreatment of liposomes with soluble linear glucan (laminarin) decreased liposome binding in both Aspergillusand Candidafungal hyphae, while growth of Aspergillushyphae in the presence of an agent that increases fungal cell wall surface exposure of linear β-glucans without cell death (caspofungin) increased liposome uptake throughout the Aspergillusfungal cell wall. Increasing the polyethylene glycol (PEG) concentration in liposomes from 0 to 30% significantly increased fungal uptake of liposomes that was only modestly attenuated when fungal cells were incubated in serum concentrations ranging from 10 to 100%. The presence of β-glucans on the fungal hyphae cell walls of Aspergillus fumigatusis one of the factors responsible for mediating the binding of liposome carriers to the hyphae and could explain possible synergy reported between liposomal amphotericin B and echinocanins.
- Published
- 2012
- Full Text
- View/download PDF
42. Abdominal Computed Tomography and the Placement of Inferior Vena Caval Filters
- Author
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Vesco, Paul A., Falimirski, Mark E., Williams, H Kenneth, Rodriguez, Aurelio, and Young, Joseph
- Abstract
Standard cavography is performed with iodinated contrast material with plain film or digital subtraction technique. However, preplacement imaging may change final inferior vena cava filter (IVC) placement in 11 to 26% of patients. This study will examine the use and reliability of incidental spiral computed abdominal tomography (CAT) scans for the placement of IVC filters.
- Published
- 2006
- Full Text
- View/download PDF
43. Short-Term Predictors and Long-Term Outcome after Ruptured Abdominal Aortic Aneurysm Repair
- Author
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Piper, Greta, Patel, Nilesh A., Chandela, Sweeta, Benckart, Daniel H., Young, Joseph C., Collela, Joseph J., and Healy, Dean A.
- Abstract
Few data exist in regard to long-term and functional outcome after ruptured abdominal aortic aneurysm (rAAA) repair. The present study provides such follow-up and defines the impact of variables used to grade resuscitation efforts [base deficit (BD) and core temperature (cT)]. One hundred forty-seven patients presenting with rAAA were retrospectively reviewed. Overall perioperative mortality was 35 per cent (51/147) and mean age was 72 years. Survival data were available for 99 per cent of patients with a mean and median follow-up of 45 months. Life table analysis revealed one-, 2-, and 5-year survival to be 81, 75, and 58 per cent, respectively. Eighty-three per cent of patients reported a quality of life equal to that of their preoperative status. Both initial cT (P= 0.02) and BD (P= 0.03) were significantly associated with perioperative mortality. Using a logistic regression model cT remained a significant factor (P= 0.006) associated with survival. Smoking, hypertension, diabetes, chronic obstructive pulmonary disease, mode of transportation, and surgeon's training were not significant. Despite the advanced age of the present cohort, acceptable perioperative mortality and long-term survival rates were attained. The majority of patients resumed a lifestyle comparable to that of their preoperative state; therefore, long-term longitudinal follow-up suggests that aggressive management with rapid correction of BD and cT results in excellent functional outcome.
- Published
- 2003
- Full Text
- View/download PDF
44. Soil physiochemical properties and carbon sequestration of Urban landscapes in Lubbock, TX, USA.
- Author
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Sapkota, Manish, Young, Joseph, Coldren, Cade, Slaughter, Lindsey, and Longing, Scott
- Subjects
CARBON sequestration ,LANDSCAPES ,HUMUS ,URBAN soils ,CARBON in soils - Abstract
Soil organic matter (SOM) accumulation and carbon (C) sequestration are ecosystem services (ESs) provided by urban landscapes that are dominated by continuous grass cover, such as residential lawns. Organic matter and C sequestration are expected to increase over time, but few studies have determined potential soil organic carbon (SOC) accumulation from residential lawns in semiarid climates. The objectives were to evaluate physiochemical attributes of urban soils established under turfgrass landscapes of different ages and determine soil factors that differentiate urban soils in semiarid climate of Lubbock, TX. Soil samples (0−10 cm) were obtained from 10 residential lawns of homes built: pre-1970 (oldest), 1971−1990 (middle), 1991−2010 (newer), and after 2011 (newest). Soil texture, bulk density, extractable nutrients [phosphorus (P), potassium (K), calcium (Ca), magnesium (Mg), and iron (Fe)], pH, SOM, SOC, and total nitrogen (TN) were determined. Bulk density and pH were highest in newest homes and lowest in oldest homes. Increasing years of lawn establishment increased SOM, SOC, and TN content. Linear regression determined 0.036 % annual increase in SOM for residential lawns, but SOC accumulated at 0.021 kg C m
−2 yr-1 for 53.6 yr. In principal component (PC) analysis, SOM, SOC, and TN contributed most to PC1 (36.2 %) reflecting components separating residential lawns by years of establishment, and primarily soil texture components for PC2 (22.5 %). The results of this study show that home age is a strong determinant of soil carbon content in semiarid urban turfgrass systems, with the greatest accumulation threshold in oldest homes over 50 years of age. [ABSTRACT FROM AUTHOR]- Published
- 2020
- Full Text
- View/download PDF
45. Celiac Steal Resulting in Chronic Intestinal Ischemia
- Author
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Kupferschmid, John P., Dickson, Christopher S., and Young, Joseph C.
- Abstract
There is considerable controversy regarding the existence of celiac axis compression syndrome. Despite this, there is clearly a subset of patients with extrinsic compression of the celiac axis who have symptoms and who benefit from operative therapy. Clinical features that may help to identify those patients who are most likely to respond to surgical therapy have been studied; however, the authors present a patient who had a favorable surgical outcome despite lacking many of these clinical features. The patient had significant celiac steal. They suspect that the presence of celiac steal may be an important determinant of a successful surgical outcome.
- Published
- 1992
- Full Text
- View/download PDF
46. Methods school Administrators Can Use To Help Teachers Manage Stress
- Author
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Frey, Diane and Young, Joseph A.
- Abstract
These writers suggest a number of ways principals can help teachers to reduce stress, and thus avoid burnout. The same tech niques, of course, will work for ad ministrators them selves.
- Published
- 1983
- Full Text
- View/download PDF
47. Self-Concept Continuum for Understanding Student Behavior
- Author
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Frey, Diane and Young, Joseph A.
- Abstract
The educator who deals effectively with student misbehavior is probably focusing on the causes of that behavior, these authors believe. A process designed to promote understanding of student motivation, andto help in dealing effectively with misbehavior, is outlined in this article.
- Published
- 1979
- Full Text
- View/download PDF
48. Managing Conflict in Educational Settings
- Author
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Frey, Diane and Young, Joseph A.
- Abstract
Outlined here is a management process designed for use by educators in resolving conflict situations. The process has been utilized successfully in a wide range of problem situations.
- Published
- 1978
- Full Text
- View/download PDF
49. PC sound and video compression boards for information infrastructure
- Author
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Kim, Yongmin, Young, Joseph, and Gove, Robert J.
- Published
- 1994
- Full Text
- View/download PDF
50. DELAYED RUPTURE OF THE SPLEEN—MYTHS FACTS AND THEIR IMPORTANCE
- Author
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Kluger, Yoram, Paul, Douglas B., Raves, John J., Fonda, Michele, Young, Joseph C., Townsend, Ricard N., and Diamond, Daniel L.
- Abstract
Over a 1-year period, three patients were seen in our trauma service with delayed bleeding (≥7 days) from an initially inapparent splenic injury. This entity was defined as a late occurrence of signs and symptoms attributed to splenic injury not detected by diagnostic computed tomographic (CT) scanning during the initial examination. We believe that this represents an “Injury in evolution” minor enough to go undetected on initial CT scans of the abdomen. A high index of suspicion and liberal utilization of imaging techniques are essential for the identification of delayed splenic rupture. Further multicenter studies are required to delineate the true incidence of its occurrence and its clinical significance. We conclude that “delayed rupture” of the spleen is a true clinical entity. The occurrence of a delayed rupture may prove hazardous to patients discharged early from the hospital after blunt abdominal injury. A classification system to assess this type of injury is suggested.
- Published
- 1994
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