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Background: Total antioxidant capacity (TAC) reflects an individual's overall antioxidant intake. We sought to clarify whether higher TAC is associated with lower risks of pancreatic cancer incidence and mortality in the U.S. general population. Methods: A total of 96,018 American adults were identified from the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. A ferric-reducing ability of plasma score was used to reflect an individual's TAC intake from diet and/or supplements. Cox regression was used to calculate hazard ratios (HR) for pancreatic cancer incidence, and competing risk regression was used to calculate subdistribution HRs for pancreatic cancer mortality. Restricted cubic spline regression was used to test nonlinearity. Results: A total of 393 pancreatic cancer cases and 353 pancreatic cancer-related deaths were documented. Total (diet + supplements) TAC was found to be inversely associated with pancreatic cancer incidence (HRquartile 4 vs. quartile 1 = 0.53; 95% confidence interval, 0.39-0.72; Ptrend = 0.0002) and mortality (subdistribution HRquartile 4 vs. quartile 1 = 0.52; 95% confidence interval 0.38-0.72; Ptrend = 0.0003) in a nonlinear dose-response manner (all Pnonlinearity < 0.01). Similar results were observed for dietary TAC. No association of supplemental TAC with pancreatic cancer incidence and mortality was found. Conclusions: In the U.S. general population, dietary but not supplemental TAC level is inversely associated with risks of pancreatic cancer incidence and mortality in a nonlinear dose-response pattern. Impact: This is the first prospective study indicating that a diet rich in antioxidants may be beneficial in decreasing pancreatic cancer incidence and mortality. [ABSTRACT FROM AUTHOR]

In order to realize the immobilization of collagen, chitosan and sericin on the surface of polypropylene fabric, the fabric is treated by ammonia and nitrogen low temperature plasma to produce reactive groups, and then the epoxy compounds (ethylene glycol diglycidyl ether, trimethylolpropane triglycidyl ether) are used as crosslinkers for a bridging process. Single factor experiment is carried out to investigate the influence of crosslinking parameters (temperature, time and the dosage of crosslinker) on immobilization yield. Chemical composition changes on the surface of the treated samples is analyzed by infrared spectroscopy, which indicated that the ammonia plasma treatment can produce more active groups. The results showed that immobilization rate of samples crosslinked by ethylene glycol diglycidyl ether is superior to that of trimethylolpropane triglycidyl ether. It also can be found that the fabric had a better wettability and antimicrobial properties. The whiteness and comfort property of chitosan-polypropylene fabric decreased slightly. [ABSTRACT FROM AUTHOR]