Search

Your search keyword '"Wichert-Ana L"' showing total 3 results
Start Over Author "Wichert-Ana L" Database Supplemental Index
3 results on '"Wichert-Ana L"'

1. Cortical malformations are associated with a rare polymorphism of cellular prion protein

Author

Walz, R, Castro, R M.R.P.S., Landemberger, M C., Velasco, T R., Terra-Bustamante, V C., Bastos, A C., Bianchin, M, Wichert-Ana, L, Araújo, D, Alexandre, V, Santos, A C., Machado, H R., Carlotti, C G., Brentani, R R., Martins, V R., and Sakamoto, A C.

Abstract

Studies in animals lacking the cellular prion protein (PrPc) gene (Prnp) showed higher neuronal excitability in vitro and increased sensitivity to seizures in vivo. The authors previously reported a rare polymorphism at codon 171 (Asn→Ser) of human Prnpto be associated with mesial temporal lobe epilepsy related to hippocampal sclerosis. They demonstrated that the same variant allele is also associated with symptomatic epilepsies related to different forms of malformations of cortical development.

Published
2004
Full Text
View/download PDF

2. Surgical outcome in mesial temporal sclerosis correlates with prion protein gene variant

Author

Walz, R., Castro, R. M.R.P.S., Velasco, T. R., Alexandre, V., Lopes, M. H., Leite, J. P., Santos, A. C., Assirati, J. A., Wichert-Ana, L., Terra-Bustamante, V. C., Bianchin, M. M., Maciag, P. C., Ribeiro, K. B., Guarnieri, R., Araújo, D., Cabalero, O., Moura, R., Salim, A. C.M., Kindlmann, K., Landemberger, M. C., Marques, W., Fernandes, R. M.F., Serafini, L. N., Machado, H. R., Carlotti, C. G., Brentani, R. R., Sakamoto, A. C., and Martins, V. R.

Abstract

Mesial temporal lobe epilepsy related to hippocampal sclerosis (MTLE-HS) is the most common surgically remediable epileptic syndrome. Ablation of the cellular prion protein (PrPc) gene (PRNP) enhances neuronal excitability of the hippocampus in vitro and sensitivity to seizure in vivo, indicating that PrPcmight be related to epilepsy.

Published
2003
Full Text
View/download PDF

3. Accuracy of ictal SPECT in mesial temporal lobe epilepsy with bilateral interictal spikes

Author

Velasco, T. R., Wichert–Ana, L., Leite, J. P., Araújo, D., Terra-Bustamante, V. C., Alexandre, V., Kato, M., Assirati, J. A., Machado, H. R., Carlotti, C. G., and Sakamoto, A. C.

Abstract

In mesial temporal lobe epilepsy (MTLE), the rate of correct seizure lateralization of ictal semiology and ictal EEG is better for patients with unilateral interictal spikes (UIS) than for patients with bilateral interictal spikes (BIS), possibly due to rapid seizure propagation patterns associated with bilateral epileptogenesis. In this study, the authors investigated if ictal SPECT is a reliable diagnostic test for both UIS and BIS patients.

Published
2002

Catalog

Books, media, physical & digital resources
See catalog results