30 results on '"Wang, Xiaochao"'
Search Results
2. Dielectric Ceramics Database Automatically Constructed by Data Mining in the Literature.
- Author
-
Wang, Xiaochao, Zhang, Wanli, and Zhang, Wenxu
- Published
- 2024
- Full Text
- View/download PDF
3. Enhanced hydrothermal liquefaction of tires using zinc and MoS2
- Author
-
Li, Mingzhou, Wang, Likun, Wang, Wei, Wang, Xiaochao, and Yu, Jie
- Abstract
This study introduces a novel approach for tire liquefaction employing zinc and unsupported catalyst MoS2to mitigate oxygen, nitrogen, and sulfur content, while inhibiting poly-aromatic formation. Autoclave experiments were conducted under subcritical water conditions at 360 and 410 °C. Comprehensive characterization of char and oil was performed, encompassing elemental analysis, functional-group assessment, and composition analysis using gas chromatography-mass spectrometry (GC-MS) and Fourier-transform ion cyclotron resonance mass spectrometry (FT-ICR MS). During the liquefaction, zinc metal pellets react with water to form ZnO and hydrogen, aiding hydrogenation, and MoS2preserves its catalytic stability. ZnO shows a catalytic effect on deoxygenation, desulfurization, and denitrification reactions. However, the reaction between ZnO and H2S is not favorable under hydrothermal conditions. Zinc and MoS2synergistically promote cracking of heavier compounds into lighter ones, particularly evident at higher temperatures, without diminishing the overall oil yield. Incorporating zinc pellets and MoS2slightly facilitates sulfur and oxygen migration from liquid to solid and gas phases. FT-ICR MS analysis reveals oxygen, sulfur, and nitrogen-containing compounds in heavy fraction of oils. The oxygen-containing compounds, predominantly comprised of stearic acid and its derivatives, are identified. Concurrently, the nitrogen-containing compounds manifest primarily as basic nitrogen compounds. MoS2possesses the capability of forming more N-containing compounds, leading to the generation of a broader spectrum of N-containing compounds. This work elucidates the synergistic role of zinc-assisted catalysis and MoS2, offering insights into tire liquefaction mechanisms and product composition, vital for sustainable waste management and resource recovery.
- Published
- 2024
- Full Text
- View/download PDF
4. A Practical Data Audit Scheme With Retrievability and Indistinguishable Privacy-Preserving for Vehicular Cloud Computing
- Author
-
Zhou, Zequan, Luo, Xiling, Wang, Yupeng, Mao, Jian, Luo, Feixiang, Bai, Yi, Wang, Xiaochao, Liu, Gang, Wang, Junjun, and Zeng, Feng
- Abstract
In vehicular cloud computing (VCC), cloud servers provide enormous storage and powerful computing capacity to Vehicular Ad-hoc Networks (VANETs). Resource-constrained vehicles outsource data to vehicular cloud platforms for timely traffic safety services, e.g., navigation, accident alarms, etc. Auditing the authenticity of data has become a critical issue in outsourcing data to untrusted servers. Existing data audit methods encode all data with error correction codes (ECC) techniques that retrieve corrupted data by downloading all data. The communication overhead of such methods is
($O(n)$ is the number of data blocks) which is unbearable for vehicles with limited resources. In addition, these schemes employ an inaccurate privacy-preserving model. This will lead to data leakage in the third-party audit process. Although they use randomness to confuse parts of the proof that is used to prove the data state, a small amount of information is still distinguishable. For such, in this paper, we propose a practical data audit scheme with retrievability and indistinguishable privacy-preserving to efficiently audit the state of outsourced data. We improve the Invertible Bloom Filter (IBF) to compress redundancy locally, which can retrieve corrupted data without prior context. Furthermore, we define an indistinguishable privacy-preserving model to capture the complete semantics of repeated audit attacks and achieve indistinguishability in the audit. We prove that our scheme is secure against adaptive chosen message attacks and is indistinguishable privacy-preserving against repeated audit attacks. The experiment results demonstrate that for 1.9 GB data when$n$ blocks are corrupted, auditors complete a check in 3.31 seconds with 99% confidence, and vehicles retrieve corrupted data in 3.16 seconds with 16.67 MB communication overhead.$\sqrt[]{n}$ - Published
- 2023
- Full Text
- View/download PDF
5. Theoretical analysis of frequency modulation-to-amplitude modulation on the final optics and target of the SG II-Up laser facility
- Author
-
Zhang, Yujia, Fan, Wei, Wang, Jiangfeng, Wang, Xiaochao, Lu, Xinghua, Huang, Dajie, Xu, Shouying, Zhang, Yanli, Sun, Mingying, Jiao, Zhaoyang, Zhou, Shenlei, and Jiang, Xiuqing
- Abstract
AbstractFrequency modulation (FM)-to-amplitude modulation (AM) conversion is an important factor that affects the time–power curve of inertial confinement fusion (ICF) high-power laser facilities. This conversion can impact uniform compression and increase the risk of damage to optics. However, the dispersive grating used in the smoothing by spectral dispersion technology will introduce a temporal delay and can spatially smooth the target. The combined effect of the dispersive grating and the focusing lens is equivalent to a Gaussian low-pass filter, which is equivalent to 8 GHz bandwidth and can reduce the intensity modulation on the target to below 5% with 0.3 nm @ 3 GHz + 20 GHz spectrum phase modulation. The results play an important role in the testing and evaluating of the FM-to-AM on the final optics and the target, which is beneficial for comprehensively evaluating the load capacity of the facility and isentropic compression experiment for ICF.
- Published
- 2024
- Full Text
- View/download PDF
6. Optimization of metro wheel reprofiling based on cluster analysis
- Author
-
Lin, Zonghui, Lu, Zhenggang, Yong, Xinjian, Wei, Juyao, and Wang, Xiaochao
- Abstract
According to the characteristics of the metro vehicles running on the same track leading to a similar wheel wear, a clustering method based on k-means is proposed. The weighted wheel flange height of Sh and qR, and wheel flange thickness of Sd are used as clustering parameters. This paper classifies the treads of the wheels to be repaired and obtains a typical worn wheel profile to reprofile the wheels. Under the premise of ensuring the operation safety of vehicles, the wheel profile optimization model is established for a typical worn wheel profile based on the minimum repair volume. The optimized profile is used as the reprofiling template for all wheels in the same classification. Finally, based on the reprofiling standard for the wheel diameter difference between the left and right wheels, the optimization reprofiling of the wheel profile is achieved. The research results show that the proposed optimization strategy base on cluster analysis can significantly reduce the material removal.
- Published
- 2022
- Full Text
- View/download PDF
7. Microstructure and mechanical characteristics of Cu-12.5Ni-5Sn-xFe sintered alloys
- Author
-
Wang, Xiaochao, Li, Zhen, Du, Sanming, Wang, Jingbo, and Zhang, Yongzhen
- Abstract
The Cu-12.5Ni-5Sn-xFe alloys were prepared using powder metallurgy. The effect of the amount of Fe addition on the microstructure and mechanical characteristics of Cu-12.5Ni-5Sn-xFe alloys was investigated. The microstructure and morphology of alloys were examined by means of X-ray diffraction, scanning electron microscopy and cold field emission scanning electron microscope. Results indicate that the hardness and yield strength of the Cu-12.5Ni-5Sn alloy are improved by addition of trace amounts of Fe. The lamellar precipitates of Cu-12.5Ni-5Sn-xFe alloys are more and finer compared to those of Cu-12.5Ni-5Sn alloy. Fe can facilitate the aging process and strengthen the effect of aging-hardening.
- Published
- 2021
- Full Text
- View/download PDF
8. Dielectric Ceramics Database Automatically Constructed by Data Mining in the Literature
- Author
-
Wang, Xiaochao, Zhang, Wanli, and Zhang, Wenxu
- Abstract
Vast published dielectric ceramics literature is a natural database for big-data analysis, discovering structure–property relationships, and property prediction. We constructed a data-mining pipeline based on natural language processing (NLP) to extract property information from about 12,900 published dielectric ceramics articles and normalized more than 20 properties. The micro-F1 scores for sentence classification, named entities recognition, relation extraction (related), and relation extraction (same), are 91.6, 82.4, 91.4, and 88.3%, respectively. We demonstrated the distribution of some essential properties according to the publication years to reveal the tendency. In order to test the reliability of the data extraction, we trained an XGBoost model to predict the dielectric constant and used the SHAP module to interpret the contribution of each feature in order to identify some of the factors that determine the dielectric properties. The result shows that including Q× fin the model can increase the dielectric constant prediction accuracy. Our work can give some hints to experimentalists on their way to improve the performances of cutting-edge materials.
- Published
- 2024
- Full Text
- View/download PDF
9. Increased α-HB links colorectal cancer and diabetes by potentiating NF-κB signaling.
- Author
-
Lv, Xinyue, Ding, Peipei, Li, Luying, Li, Ling, Zhou, Danlei, Wang, Xiaochao, Chen, Jianfeng, Zhang, Wei, Wang, Qi, Liao, Tian, Wen, Wenyu, Zhou, Dawang, Ji, Qing-Hai, He, Xianghuo, Lei, Qun-Ying, and Hu, Weiguo
- Abstract
Sufficient evidence has linked many different types of cancers and T2D through shared risk factors; however, the underlying mechanisms are not fully understood. α-Hydroxybutyrate (α-HB), a byproduct metabolite increased in diabetes and cancer, including colorectal cancer (CRC), triggers lactate dehydrogenase A (LDHA) nuclear translocation. Nuclear LDHA markedly extends NF-κB nuclear retention by interacting with phosphorylated p65, leading to an increase in TNF-α production, impaired insulin secretion and the exacerbation of azoxymethane (AOM)/dextran sodium sulfate (DSS)-induced CRC and high-fat diet (HFD)-induced type 2 diabetes. Furthermore, metformin interrupted this process by inhibiting the transcription of FOXM1 and c-MYC, the resultant downregulation of LDHA expression and α-HB-induced LDHA nuclear translocation. Thus, the results reveal the elevated α-HB level could be a novel shared risk factor of linking CRC, diabetes and the use of metformin treatment, as well as highlight the importance of preventing NF-κB activation for protecting against cancer and diabetes. • α-HB accelerates the development of colorectal cancer and type 2 diabetes. • α-HB prolongs the nuclear retention of NF-κB via LDHA. • Metformin inhibits nuclear LDHA-induced NF-κB nuclear retention. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
10. All-optical arbitrary temporal shaping technology of broadband low-coherence light based on saturable absorption effect
- Author
-
Li, Ruxin, Singh, Upendra N., Jiang, Shibin, Sui, Daipeng, Li, Rao, Sun, Mingying, and Wang, Xiaochao
- Published
- 2019
- Full Text
- View/download PDF
11. Detection and analysis of the signal-to-noise ratio in the injection laser system of the Shenguang-II facility
- Author
-
Xia, Gang, Fan, Wei, Wang, Xiaochao, Wang, Jiangfeng, Huang, Dajie, Guo, Jiangtao, and Wang, Xiaoqin
- Abstract
The temporal contrast levels of laser pulses in the injection laser system of the Shenguang-II facility are accurately measured and analyzed in detail. These signal-to-noise ratio levels are determined by the extinction ratios of an acousto-optic modulator, an electro-optic intensity modulator, and a combination of a Pockels cell and thin film polarizers. In addition, a drifting direct current bias voltage of an electro-optic intensity modulator and phase modulation are also demonstrated to affect the signal-to-noise ratio of the injection laser system. With a precise control of these factors, the injection laser system can output a nanosecond laser pulse with a signal-to-noise ratio of 47.37 dB. Moreover, a nanosecond laser pulse signal-to-noise ratio measuring device with a dynamic range and accuracy of 50 and 1 dB, respectively, is developed to detect the signal-to-noise ratio of a nanosecond laser pulse, which is 47.06 dB within an accuracy range of 1 dB. The signal-to-noise ratio measuring device can detect the high contrast laser pulse for the seed source unit in the high power laser facility accurately and conveniently.
- Published
- 2018
12. High-energy master oscillator power amplifier with near-diffraction-limited output based on ytterbium-doped PCF fiber
- Author
-
Jiang, Shibin, Wang, Lijun, Jiang, Lan, Zhang, Long, Li, Rao, Qiao, Zhi, Wang, Xiaochao, Fan, Wei, and Lin, Zunqi
- Published
- 2017
- Full Text
- View/download PDF
13. Characterization of ultrashort pulses by time–frequency conversion and temporal magnification based on four-wave mixing at 1 μm
- Author
-
Qiao, Zhi, Pan, Xue, Wang, Xiaochao, Huang, Tingrui, Zhang, Peng, Fan, Wei, Li, Xuechun, and Lin, Zunqi
- Abstract
In order to characterize ultrashort pulses in real time at 1 μm wavelength, a temporal imaging structure based on the four-wave mixing effect in highly nonlinear fibers is implemented and analyzed both theoretically and experimentally. It is found that both time–frequency transfer and the temporal magnification process can be realized approximately in one structure. The pulse widths of the signal laser measured by the time–frequency transfer and the temporal magnification process are 3.2 ps and 3.1 ps, respectively, which are nearly the same and are in agreement with the result of the autocorrelator. The temporal magnification factor is 33, and the temporal resolution is 380 fs. The method based on the temporal magnification process is inherently real time and single shot, which makes it suitable for applications in the measurement of high-power ultrashort pulses. The four-wave mixing time lens promises future applications in the characterization of the single-shot high-power short laser.
- Published
- 2017
14. Real-time characterization of FM-AM modulation in a high-power laser facility using an RF-photonics system and a denoising algorithm
- Author
-
Huang, Canhong, Lu, Xinghua, Jiang, Youen, Wang, Xiaochao, Qiao, Zhi, and Fan, Wei
- Abstract
FM-AM modulation of high-power lasers significantly affects laser performance. Therefore, precise measurement of the FM-AM modulation depth is necessary. The subsequent FM-AM modulation generated by group velocity dispersion when the laser pulse propagates through a fiber affects the measurement accuracy. In order to eliminate this effect, a waveform-acquisition module is proposed that converts a broad-spectrum pulse of 1053 nm to a narrow-spectrum pulse of 1550 nm, without affecting the waveform. In addition, a signal-processing algorithm based on the orthogonal matching pursuit method is implemented to remove the sampling noise from the waveform. In this way, the signal-to-noise ratio of the measurement can be readily improved. Both theoretical and experimental results indicate that the proposed FM-AM modulation detection system is effective and economical. It can measure the FM-AM modulation depth precisely, and therefore shows considerable promise for future applications in high-power lasers.
- Published
- 2017
15. High precision long-term stable fiber-based optical synchronization system
- Author
-
Zhang, Xuping, Li, Baojun, Yu, Changyuan, Li, Yurong, Wang, Xiaochao, Jiang, Youen, Qiao, Zhi, Li, Rao, and Fan, Wei
- Published
- 2016
- Full Text
- View/download PDF
16. Suppression of FM-to-AM modulation by polarizing fiber front end for high-power lasers
- Author
-
Qiao, Zhi, Wang, Xiaochao, Fan, Wei, Li, Xuechun, Jiang, Youen, Li, Rao, Huang, Canhong, and Lin, Zunqi
- Abstract
FM-to-AM modulation is an important effect in the front end of high-power lasers that influences the temporal profile. Various methods have been implemented in standard-fiber and polarization-maintaining (PM)-fiber front ends to suppress the FM-to-AM modulation. To analyze the modulation in the front end, a theoretical model is established and detailed simulations carried out that show that the polarizing (PZ) fiber, whose fast axis has a large loss, can successfully suppress the modulation. Moreover, the stability of the FM-to-AM modulation can be improved, which is important for the front end to obtain a stable output. To verify the model, a PZ fiber front end is constructed experimentally. The FM-to-AM modulation, without any compensation, is less than 4%, whereas that of the PM fiber front end with the same structure is nearly 20%. The stability of the FM-to-AM modulation depth is analyzed experimentally and the peak-to-peak and standard deviation (SD) are 2% and 0.38%, respectively, over 3 h. The experimental results agree with the simulation results and both prove that the PZ fiber front end can successfully suppress the FM-to-AM conversion. The PZ fiber front end is a promising alternative for improving the performance of the front end in high-power laser facilities.
- Published
- 2016
17. On the Root and Primitive Significance of Greek eimi.
- Author
-
Wang Xiaochao
- Abstract
Language is the basic element of the development of culture, and is also the basic component of the theoretical philosophy. The Greek word eimi (zljxi) is such a gene of Western philosophy. It attracted great attentions of the Chinese philosophical scholars in the long-lasting discussions about "Being," because a serial of philosophical and metaphysical problems in the later Western history, and even some fundamental problems of modern Chinese philosophy, originated from this word. Greek language emerged before 13th century B. C. In the 17th -late 18th centuries, linguists assumed that Indian and European languages originated from a common primitive language, the Proto-Indo-European language, and thus Greek could be traced back to this primitive language. Different from Chinese language or other non-Indo-European languages, Greek is an inflected language, whose grammar is a specific assembly of forms of thinking, structures, inflections and suffixes. In the earlier discussions of the academic circles, some scholars confused the root and the stem of eimi, and some even advocated re-inventing Chinese translations for eimi according to its inflections as a copula. In fact, root is a concept of etymology but stem is that of morphology. Words belonging to Indo-European language are assumed to have common sources which are rooted in proto-Indo-European. If we can clarify the root of eimi, then we can also apprehend the primitive significance of eimi. It is generally recognized that eimi has two closely related roots, es- and bhu-, which are ancient and independent notional verbs, including the meaning of to exist in somewhere. C. H. Kahn holds that only es- is the only root of eimi, while bhur is the root of verbs of "to become," or "to grow." Despite the arguments on how many roots are involved, it is clear that eimi has more than one significance of to be (as a copula). One of the oldest significances of the root es- is to signify location, meaning to occupy a position in some place, from which other general significances were derived. Many linguists believe that the independent and existential usage of es- is more primitive than its copula usage which is later and derivative. This dichotomy also influences the understanding of "Being" in the English-speaking world. It is doubtable of C. H. Khan's attempt to determine the primitiveness of eimi as a copula by the statistical frequency of it in Homer's works. To settle this problem, the genealogical method is more reliable. The emergence of copula is a later fact (than that of notional verb) in all sorts of national languages, and it is also a symbol of human's mind stepping into the logical stage from pre-logical stage. [ABSTRACT FROM AUTHOR]
- Published
- 2014
- Full Text
- View/download PDF
18. Demonstration of a high-energy, narrow-bandwidth, and temporally shaped fiber regenerative amplifier
- Author
-
Qiao, Zhi, Wang, Xiaochao, Fan, Wei, and Lin, Zunqi
- Abstract
We report a high-energy and high-gain fiber regenerative amplifier for narrow-bandwidth nanosecond laser pulses that uses a Yb-doped photonic crystal fiber. The input pulse energy is 270 pJ for a 3.5 ns laser pulse with 0.3 nm (FWHM) bandwidth. At a pump laser power of 8.6 W at 974 nm, pulse energies up to 746 μJ with 1.2% (rms) energy stability are generated. To the best of our knowledge, this is the highest energy obtained in a fiber-based regenerative amplifier. A high-energy, nearly diffraction-limited, single-mode beam with a high gain of 64 dB shows promise for future application in the front ends of high-power laser facilities.
- Published
- 2015
19. Colorful Athena: On the Problem of Philosophy's Hellenism.
- Author
-
Wang Xiaochao and Chen Yuehua
- Subjects
ANCIENT philosophy ,INTERGROUP communication ,CROSS-cultural communication ,CULTURAL pluralism ,HELLENISM - Abstract
Philosophy has always resembled a cultural gene, residing in the spiritual homeland of nations; weaving through cultures and revealing the essential spirit of the times and nation. However, once the seed of philosophy has left its native country and settled on the soil of different cultures, it would either be met with praise or with criticism. The study of " philosophy's Hellenism" by Chinese scholars will provide us with a new perspective for a deeper understanding of the origin and development of Western philosophy. In this way, we may further understand the general rules for cross-cultural transmission of philosophy. This may also lead to new ways of thinking about the Sinization of Marxist philosophy and the legitimacy of Chinese philosophy. Heidegger and Derrida confirmed that the history of philosophy started from Greece, and Hellenism is its essential character. Philosophy is the product of human thinking transitioning from the non-rational into the threshold of Nationality. Emerging first in ancient Greece, it has managed to carry this "Hellenism" throughout its developmental history. "Hellenism" is thus the feature or characteristic of the Greek way of life(including its way of thinking). In researching later periods of Greek philosophy, scholars need to expand their scope, so as to focus not only on the Aegean Sea, but also on the entire Mediterranean World. As such, we must use a cultural perspective and a cross-cultural research methodology to investigate the origin and development of philosophy. By studying the spread of Greek philosophy in the Mediterranean cultural world, we discover that Greek philosophy crossed cultural borders without losing its Hellenist character but diversified its content and forms. The so-called "orthodox Greek philosophy" did not actually exist. Having such a grasp of Greek philosophy, we must adopt a relatively broader definition of philosophy that stretches back to its original meaning of "wisdom" or "thought." In this manner, we can avoid reducing philosophy to a skeleton of only constructed concepts and categories that neglects its profound contents. In a global context, the issue of "philosophy's Hellenism" is also an issue of philosophy's nationality. In comparing Eastern and Western cultures, Hegel and Husserl expressed similar ideas, namely that philosophy emerged in the West and not in the East. Philosophy is "a critical theoretical thinking and an ultimate concern with the world (including society and the human person)." On the horizon of the Aegean Sea, the Greeks, by absorbing other nations' cultural elements, had enhanced their own ability for rational thinking, and became the first to cross the threshold of rationality, thus creating philosophy. It is under this context of a comparative study of the history of culture that we claim that philosophy, as a way of rational thinking, has its origin in ancient Greece. However, in the present world context and from a global perspective, philosophy is universal while Greek philosophy is specific. When another nation's ability of rational thinking reaches a certain level, its culture will inevitably encounter Greek philosophy and will eventually create a new philosophy expressed in its own national language. [ABSTRACT FROM AUTHOR]
- Published
- 2012
- Full Text
- View/download PDF
20. Improved, feature-centric EMD for 3D surface modeling and processing.
- Author
-
Hu, Jianping, Wang, Xiaochao, and Qin, Hong
- Subjects
HILBERT-Huang transform ,GEOMETRIC modeling ,GEOMETRIC surfaces ,COORDINATES ,LAPLACIAN matrices ,SMOOTHNESS of functions - Abstract
Abstract: Since late 1990s, Empirical Mode Decomposition (EMD) starts to emerge as a powerful tool for processing non-linear and non-stationary signals. Nonetheless, the research on exploring EMD-relevant techniques in the domain of geometric modeling and processing is extremely rare. Directly applying EMD to coordinate functions of 3D shape geometry will not take advantage of the attractive EMD properties. To ameliorate, in this paper we articulate a novel 3D surface modeling and processing framework founded upon improved, feature-centric EMD, with a goal of realizing the full potential of EMD. Our strategy starts with a measure of mean curvature as a surface signal for EMD. Our newly-formulated measure of mean curvature is computed via the inner product of Laplacian vector and vertex normal. Such measure is both rotation-invariant and translation-invariant, facilitates the computation of different scale features for original surfaces, and avoids boundary shrinkage when processing open surfaces. Moreover, we modify the original EMD formulation by devising a feature-preserving multiscale decomposition algorithm for surface analysis and synthesis. The key idea is to explicitly formulate details as oscillation between local minima and maxima. Within our novel framework, we could accommodate many modeling and processing operations, such as filter design, detail transfer, and feature-preserving smoothing and denoising. Comprehensive experiments and quantitative evaluations/comparisons on popular models have demonstrated that our new surface processing methodology and algorithm based on the improved, feature-centric EMD are of great value in digital geometry processing, analysis, and synthesis. [Copyright &y& Elsevier]
- Published
- 2014
- Full Text
- View/download PDF
21. Intracellular complement C5a/C5aR1 stabilizes β-catenin to promote colorectal tumorigenesis
- Author
-
Ding, Peipei, Xu, Yanqing, Li, Luying, Lv, Xinyue, Li, Ling, Chen, Jianfeng, Zhou, Danlei, Wang, Xiaochao, Wang, Qi, Zhang, Wei, Liao, Tian, Ji, Qing-Hai, Lei, Qun-Ying, and Hu, Weiguo
- Abstract
Complement is operative in not only the extracellular but also the intracellular milieu. However, little is known about the role of complement activation inside tumor cells. Here, we report that intracellular C5 is cleaved by cathepsin D (CTSD) to produce C5a in lysosomes and endosomes of colonic cancer cells. After stimulation by C5a, intracellular C5aR1 assembles a complex with KCTD5/cullin3/Roc-1 and β-catenin to promote the switch of polyubiquitination of β-catenin from K48 to K63, which enhances β-catenin stability. Genetic loss or pharmacological blockade of C5aR1 dramatically impedes colorectal tumorigenesis at least by destabilizing β-catenin. In human colorectal cancer specimens, high levels of C5aR1, C5a, and CTSD are closely correlated with elevated β-catenin levels and a poor prognosis. Importantly, intracellular C5a/C5aR1-mediated β-catenin stabilization is also observed ubiquitously in other cell types. Collectively, we identify a machinery for β-catenin activation and provide a potential target for tumor prevention and treatment.
- Published
- 2022
- Full Text
- View/download PDF
22. Pulse multi-pass stretcher using linear chirped fiber Bragg grating
- Author
-
Tünnermann, Andreas, Liu, Zejin, Wang, Pu, Tang, Chun, Zhang, Chengtao, Wang, Xiaochao, Fan, Wei, Rao, Daxing, and Lin, Zunqi
- Published
- 2013
- Full Text
- View/download PDF
23. Research for ultra-short pulse ablation of dielectric film mirror
- Author
-
Xiong, Zhimin, Zhang, Panzheng, Jiang, Youen, Wang, Xiaochao, Huang, Dajie, Fan, Wei, and Li, Xuechun
- Abstract
In high-power laser system, in order to extend the components' service life and reduce the operation costs, more attentions should be pay at the research for damages ablation at multi-layer optical components and other high load optical components. 240ps, 35ps, 6ps 1053nm laser pulses has been used to investigate damage ablation and damage resistant experiments at 0° high reflection films. By comparing the damage morphology and damage resistant threshold of the ablation pits at different pulses width, it was superior to use ultra-short pulse to repair multi-layers optical components. It was found that the shorter pulse width has been used, the higher the damage resistant threshold and the lower the laser modulation. Furthermore, the finite-difference time-domain method was used to simulate the electric-field intensification within the large size damage region of multilayer films.
- Published
- 2011
- Full Text
- View/download PDF
24. On the study of foreign philosophy in Chinese cultural construction and its future
- Author
-
Wang, Xiaochao
- Abstract
Abstract: Since the “Conference on Foreign Philosophy” held in Wuhu in October 1978, the study of foreign philosophy in China has undergone a prosperous stage. This article discusses the significance of the study of foreign philosophy in the context of renovation, transformation and remolding of Chinese contemporary culture, explores the role of the discipline in the context of Chinese cultural construction, and anticipates the future of this discipline. A cross-cultural perspective is needed for a proper understanding of the significance of the learning and study of foreign philosophy in Chinese cultural construction; otherwise we might fall into cultural conservationism. Secondly, to make philosophy and social sciences prosperous is also a task for foreign philosophy studies, and whether or not foreign philosophy can be well studied should be a mark of the prosperousness of the construction of Chinese culture. Finally, philosophy is a product of human beings and should eventually serve human beings. Chinese culture should open itself up to the world and so should foreign philosophy studies in China.
- Published
- 2006
- Full Text
- View/download PDF
25. Smooth pulse recovery based on hybrid wavelet threshold denoising and first derivative adaptive smoothing filter
- Author
-
Qian, Xinlei, Fan, Wei, Lu, Xinghua, and Wang, Xiaochao
- Abstract
AbstractBased on the pulse-shaping unit in the front end of high-power laser facilities, we propose a new hybrid scheme in a closed-loop control system including wavelet threshold denoising for pretreatment and a first derivative adaptive smoothing filter for smooth pulse recovery, so as to effectively restrain the influence of electrical noise and FM-to-AM modulation in the time–power curve, and enhance the calibration accuracy of the pulse shape in the feedback control system. The related simulation and experiment results show that the proposed scheme can obtain a better shaping effect on the high-contrast temporal shape in comparison with the cumulative average algorithm and orthogonal matching pursuit algorithm combined with a traditional smoothing filter. The implementation of the hybrid scheme mechanism increased the signal-to-noise ratio of the laser pulse from about 11 dB to 30 dB, and the filtered pulse is smooth without modulation, with smoothness of about 98.8%.
- Published
- 2021
- Full Text
- View/download PDF
26. Spectral control of the joule level broadband laser amplifier system based on ASE source
- Author
-
Zhu, Jianqiang, Chen, Weibiao, Zhang, Zhenxi, Zhong, Minlin, Wang, Pu, Qiu, Jianrong, Guo, Jiangtao, Wang, Jiangfeng, Wang, Xiaochao, Sun, Mingying, and Zhou, Qiong
- Published
- 2020
- Full Text
- View/download PDF
27. Generation of 8.5-nJ pulse from all-fiber dispersion compensation-free Yb-doped laser
- Author
-
Zhang, Panzheng, Fan, Wei, Wang, Xiaochao, and Lin, Zunqi
- Abstract
We report the generation of an 8.5-nJ chirped pulse from a mode-locked all-fiber Yb-doped laser. Mode-locking is achieved through nonlinear polarization evolution (NPE) along with spectral filtering. The laser delivers 135 mW of average output power with positively chirped 10.9-ps pulses. The pulse repetition rate is 15.9 MHz, which results in an energy of 8.5 nJ per pulse. The externally dechirped pulse duration is 223 fs, and the pulse energy is 6 nJ, which corresponds to the peak power of ~27 kW.
- Published
- 2010
28. High-energy square pulses and burst-mode pulses in an all-normal dispersion double-clad mode-locked fiber laser
- Author
-
Qiao, Zhi, Wang, Xiaochao, Wang, Chao, Jing, Yuanyuan, Fan, Wei, and Lin, Zunqi
- Abstract
A double-clad Yb-doped mode-locked fiber laser that can operate in burst-mode and square-pulse states is experimentally investigated. In the burst-mode state, a burst train with 55 pulses of 500 ps duration is obtained. In the square-pulse state, which is similar to noiselike pulses, the maximum pulse energy is 820 nJ and the duration can be tuned from 15.8 to 546 ns. The square pulses have a narrow and multipeak spectrum, which is quite different from that of normal noiselike pulses. The fiber laser promises an alternative formation mechanism for burst-mode and square-pulse mode-locked fiber lasers.
- Published
- 2016
- Full Text
- View/download PDF
29. 1053-nm all-fiber multi-pulse phase modulator for chirped pulse amplification
- Author
-
Bao, Weimin, Lv, Yueguang, Jing, Yuanyuan, Wang, Xiaochao, Fan, Wei, Qiao, Zhi, and Chen, Xin
- Published
- 2016
- Full Text
- View/download PDF
30. 1 053-nm all-fiber pulse multi-pass stretcher using a linear chirped fiber Bragg grating
- Author
-
Zhang, Chengtao, Wang, Xiaochao, Fan, Wei, Rao, Daxing, and Lin, Zunqi
- Abstract
An all-fiber optical laser pulse multi-pass stretcher using a chirped fiber Bragg grating (CFBG) is demonstrated. Pulses from a 1 053-nm mode-locked fiber seed oscillator are stretched by multiple passing through a chirped fiber grating set in a fiber regenerative amplifier structure. We stretch the pulse from 16 ps to 1.855 ns after it transmits seven loops in the stretcher. The main factors that affect the stretching results are discussed.
- Published
- 2013
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.