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Introduction: Hugo Robot-Assisted Surgery (RAS) System has been conceived with enhanced modularity but its role for nephron-sparing surgery setting still remains poorly explored. We aimed to describe our experience in robot-assisted partial nephrectomy (RAPN) with a three-arms setting for the first off-clamp series using the new Hugo RAS System.Methods: Patients were placed on an extended flank position at the margin of the surgical bed with a slightly flexion (45°). The first 11 mm robotic trocar (camera port) was placed along the pararectal line 14 ± 2 cm far from the umbilicus. The pneumoperitoneum was then induced through the AirSeal system (SurgiQuest, Milford, Connecticut, USA©). Two more 8 mm operative robotic ports were placed under direct vision, either 8 ± 1 cm far from optic’s port. Two 12 mm laparoscopic ports for bed-assistant were placed between robotic ports. Monopolar curved shears, fenestrated grasper, and large needle driver were used in a three-instruments configuration.Results: Off-clamp RAPN was successfully performed in seven patients with cT1 renal masses using a trans-peritoneal route. Median port placement and docking time was 6 min (IQR, 4–8 min). Hemostasis was achieved through renorraphy using a single transfix stitch with sliding clips technique. There was no need for additional ports placement. No intraoperative complications occurred, no clashing of robotic instruments or between the robotic arms was observed. No technical failures of the system occurred. Median console time was 83 min (IQR, 68–115 min). Median estimated blood loss were 200 ml (IQR, 50–400 ml). All patients were discharged between post-operative day 2 and 3, without the need of hospital readmission. No complications were recorded within the first 30 post-operative days.Conclusions: We performed the first series of off-clamp RAPN using the novel HUGO RAS System. This novel robotic platform showed an easy-friendly docking system, providing excellent perioperative outcomes with a simple three-arms configuration.

Screening for mutations in the entire Cystic Fibrosis gene (CFTR)of Brazilian infertile men with congenital absence of vas deferens, in order to prevent transmission of CFTRmutations to offspring with the use of assisted reproductive technologies.

To assess efficacy and safety of a treatment regimen based on rectal administration of Boswellia resin extract and propolis derived polyphenols in patients with type IIIa/IIIb chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS).

Currently, there has been a growing demand for restorations of anterior teeth in the routine of doctors in dental offices. With advances in adhesive technology and good properties of the available ceramics, the use of ceramic veneers has been offered as a treatment option for cases where teeth have minor color changes and shape and position changes. Through careful treatment planning, it is possible to conservatively use ceramic veneers in the treatments, applying techniques with minimal wear of the teeth and obtaining excellent aesthetic results with mechanical stability and biocompatibility with the periodontal tissues and clinical longevity. This clinical case report was used to design the digital smile, which guided the production of the diagnostic waxing of the superior model. Silicone guides were then made to create the mock-up, orienting enamel/dentin wear and assisting the preparation of the crowns with bis-acryl resin. When the wear was finished, the gingival separation was performed using the double-thread technique. In the molding process, the second wire was withdrawn and the molding material flowed into the gingival groove, copying the terminal region. After analysis of the quality of the impression, the temporary crowns were made with bis-acryl resin, using the guide. The color of the cementing agent was chosen using a glycerin-based compound which simulates the final color of the cement. After two hours of drying, two different layers of silane were applied for 60 seconds. After the preparation of the piece, gingival isolation and separation were done. The dental substrate was degreased with detergent solution and conditioned with 37% phosphoric acid for 15 seconds and then washed for 45 seconds for subsequent drying, leaving the substrate moistened. The adhesive system was applied for 30 seconds, waiting for the adhesive to penetrate into the conditioned dentinal tubules. A light air jet was applied, and then each tooth was photopolymerized for 30 seconds. The resin cement was placed inside the pieces and placed in position and photopolymerized. The excess cement was removed; after a layer of glycerin in the cervical region, aiming to block the entry of oxygen and polishing was performed. The purpose of this case report was to describe a sequence of clinical steps, from planning to cementation, in a case of aesthetic correction using feldspathic ceramic veneers.

The possibility to sinter β‐spodumene to near‐theoretical density is studied as well as the influence of compositional changes such as variations of the Li2O, Al2O3, and SiO2contents and additions of other oxides (e.g.