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Introduction: Malignant tumors of the head and neck are heterogeneous group of tumors. Determining the degree of invasion and the extent of the disease is necessary for further treatment. The spread of metastases beyond the metastatic lymph nodes represents a significant prognostic factor. Invasion of an altered lymph node in the wall of an artery is rare. The radiological methods for assessing tumor invasion of artery walls are CT and MRI. Ultrasound assessment of invasion of the artery wall was used previously, but the method was abandoned. CT assessment is insufficiently reliable. Vessel wall invasion is considered if the tumor has invaded more than 50 % of the artery circumference or when they are in near contact within more than 30 mm. Other parameters are reduction of fatty tissue between the artery and the metastatic lymph node or compression of the artery. Ultrasound monitoring of wall mobility has not been investigated yet. Aims of this study is to determine the mobility of the artery wall close to metastatic lymph node using ultrasound and to determine the correlation of CT and US in the assessment of artery invasion. Materials and methods: The study included 16 patients with malignant disease of head and neck who underwent a CT scan on which metastatic lymph nodes and infiltration of the artery wall were described. Metastatic lymph nodes were confirmed cytologically and also using ultrasound which monitored the mobility of the wall of the infiltrated artery. Results: The infiltrated part of the artery wall described by CT has shown decreased mobility using US compared to the non-infiltrated part of the wall. Comparison of CT and US assessment of vessel wall invasion showed strong correlation. Conclusion: US assessment of motility is as valuable in the assessment of vessel wall invasion as CT standardized parameters. [ABSTRACT FROM AUTHOR]