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The pandemic caused by COVID-19 hinders everything on earth, including physical and mental health, daily life and the global economy. Currently, there are no defined drugs and few vaccines available on the market to combat SARS-CoV-2. A number of organic compounds have been designed and tested against the virus, but they have not shown promising activities. N -heterocycles, which are abundant in nature, is a significant source of pharmacologically active compounds. N -heterocycles have the potential to exert Anti- SARS-CoV-2 activity via various antiviral mechanisms, and some of them, have already used in clinics or under clinical evaluations for the processing of COVID-19. Therefore, N -heterocycles occupies an important position in the discovery of novel anti-SARS-CoV-2 agents. The current study is an effort to collect information's covering the articles published from 2019 to the beginning of this year 2022, regarding the recent development of N -heterocycles derivatives; indazole, triazolopyrimidine, pyrazolopyrimidine, quinoxaline, benzimidazole, benzodiazepine, indole, and quinoline, as potential anti-SARS-CoV-2 agents, their structure-activity relationship and mechanisms of action. [Display omitted] • The articles published from 2019 to 2022 about the anti-SARS-CoV-2 activity of some N-heterocyclic compounds. • The potential anti-SARS-CoV-2 of N-heterocycles derivatives. • N-heterocycles derivatives have demonstrated significant potential for drug development due to their high compatibility and versatility. • N-heterocyclic compounds have shown promising results in inhibiting the growth of SARS-CoV-2 cells. [ABSTRACT FROM AUTHOR]

In the world, the pollution of our environment is a global phenomenon, caused by the increase of industrial effluents discharged into the atmosphere. Moreover, the textile industry, containing a lot of dye, produces troubles, most of which are toxic and non-degradable substances. Therefore, low-cost processes are used to remove these substances, such as adsorption processes. The aim of this research is to study the adsorption of methylene blue dye on powdered activated carbon prepared from spent coffee grounds, in an attempt to prove its potential as a lower cost adsorbent in the treatment of dyed water. Adsorption experiments suggested that the time to equilibrium was influenced by the initial concentration of the dye. Therefore, equilibrium is reached after 10, 20 and 30 min respectively, for methylene blue solutions at 15, 30 and 50 mg/L at pH 5.8. The whole results of the adsorption of methylene blue dye on activated carbon powder are described pseudo-second-order kinetics. The adsorption data were modeled by Langmuir, Freundlich, Temkin and Dubinin–Radushkevich adsorption isotherms. The thermodynamic parameters of the adsorbent/adsorbate system under study reveal that the adsorption process is spontaneous and endothermic in character. [ABSTRACT FROM AUTHOR]

Olive growing occupies a key position in the Moroccan economy. Generally, 65% of olive production is destined for crushing. This operation was accompanied by the generation of two by-products: Olive mill wastewater (OMW) and olive pomace (OP), the quantities of which depend on the crushing process. The composition of these by-products in organic and mineral elements helps to valorize them as compost. Some physical-chemical parameters such as pH, temperature, organic carbon and nitrogen are monitored during the composting process until stabilization after three months. The maturity of the products obtained was evaluated by the phytotoxicity test (germination index) on the germination of cress, the E4/E6 ratio, and the respirometric test. The final substance is mature and stable from the 11th week, rich in fertilizing elements (N, P, K), non-toxic and conforms to the French standard for organic amendments NF 44-51. [ABSTRACT FROM AUTHOR]

• Imidazolium ionic liquids [Imid-3PE] Br and [Imid-4PE] br were showing a good performance as corrosion inhibitors for mild steel. • A stable passive layer was formed on the mild steel surface. • [Imid-3PE] Br and [Imid-4PE] Br showed a good inhibition performance during the immersing time. • Molecular dynamics simulations were performed involving the experimental conditions. • The theoretical part was confirmed by the experimental findings. The present paper was designed to investigate an original synthesized ionic liquid (ILs) named 1-phenethyl-3-(3-phenoxypropyl)-1H-imidazol-3-ium bromide [Imid-3PE] Br, and 1-phenethyl-3-(4-phenoxybutyl)-1H-imidazol-3-ium bromide [Imid-4PE] Br as corrosion inhibitors. These inhibitors were evaluated against mild steel corrosion in 1 M hydrochloric acid medium using electrochemical techniques. PDP experiments revealed that the [Imid-3PE] Br and [Imid-4PE] Br behaved as mixte type inhibitors. Electrochemical impedance spectroscopy (EIS) results indicated that the both compounds showed a good inhibition of the steel surface with an inhibition efficiency of 95.8% for [Imid-3PE] Br and 96.7% for [Imid-4PE] Br at the optimum concentration. According to Langmuir isotherm model and the activation parameters, these ILs can be adsorbed onto the mild steel surface through physical and chemical bonds. The theoretical approach confirms the adsorption behavior of the studied ILs based on DFT calculation and molecular dynamic simulation. [Display omitted] [ABSTRACT FROM AUTHOR]

• Xanthene derivatives act as efficient and nontoxic corrosion inhibitors for mild steel. • Quantum chemical parameters and Monte Carlo simulation results are in good correlation with experimental results. • NAR2 molecules shows a high effective corrosion inhibition compared to NAR3. The synthesis, characterization, and evaluation of inhibiting performance of two xanthene derivatives, namely 3-oxo-3H-spiro[ isobenzofuran -1,9′- xanthene ]-3′,6′-diyl (3-dibenzoate) (NAR2) and 3-oxo-3H-spiro[ isobenzofuran -1,9′- xanthene ]-3′,6′-diyl (3-diacetate) (NAR3) on mild steel immersed in 1 M HCl solution are performed. The in vivo tests were carried out to confirm the non-toxicity of NAR2 and NAR3. The solutions corrosive was analyzed using UV visible Spectroscopy. The recorded spectra confirm the adsorption capacity of these molecules on the surface of iron and thereby a formation of Fe–inhibitor complex film. A combination of Scanning Electron Microscopy (SEM), and Energy Dispersive X-ray (EDX) Spectroscopy were performed to characterize the surface of mild steel, with and without the NAR2 or NAR3 inhibitors; and Electrochemical techniques were evaluated (EIS) to determine the corresponding corrosion inhibition efficiencies of NAR2 and NAR3. The Density Functional Theory (DFT)- based total energy calculations and Monte Carlo simulations were also performed to get further theoretical insights into the inhibition mechanism. The obtained results confirmed that both organic inhibitors exhibit non-toxicity, with an inhibition efficiency of 93% and 89% for NAR2 and NAR3 at 10−4 M concentrations, respectively. Also, the both inhibitor function as mixed (cathodic and anodic) type inhibitors, displace water molecules from mild steel, and form an heterogeneous films on the mild steel surface to protect against corrosion. [Display omitted] [ABSTRACT FROM AUTHOR]

This study aimed to examine the impact of operational factors on the adsorption capacity of methylene blue (MB) using a natural and cost-effective adsorbent, activated carbon from coffee grounds (CAP). The three-factor Box-Behnken design of the response surface methodology (RSM) was employed to optimize this economically viable process with maximum efficiency. Through extensive experiments, the factors influencing the adsorption process were identified, their interactions were measured, and a mathematical model was developed. The experiment evaluated the quantity of MB adsorbed by CAP based on pH (2.5–10), initial MB concentration (10–100 mg/L), and CAP adsorbent amount (0.05–0.1 g/L). The results revealed that both concentration and mass significantly influenced the decoloration enhancement. Optimal conditions for achieving a 91 % degradation efficiency were determined as 0.05 g/L adsorbent weight, 100 mg/L dye concentration, and pH 2.5, with a desirability score of approximately 0.986, aligning closely with the predictions of the BBD model. In conclusion, this research addresses a research gap by demonstrating the high effectiveness of the CAP adsorbent in removing dyes from textiles. [ABSTRACT FROM AUTHOR]

Heavy-metals water pollution is without doubt a significant environmental problem in the global context. These non-degradable chemical pollutants may be the cause of serious ecological and health issues, due to their ability of penetration and accumulation throughout the food chain exposing humans to slow but certain poisoning. In order to alleviate water stress, several technological solutions for the removal of toxic heavy metals from industrial wastewater have been implemented. The removal efficiency was often limited by the cost-effectiveness, the sludge production and the metal selectivity of the most common physico-chemical processes. Alternatively, adsorption using natural wastes from agricultural and industrial activities is a promising technic that has received great deal of attention recently. It was considered as an economic, efficient, sustainable and green process. Among the used materials, sawdust gained particular interest over other commonly used and was hence extensively reported as a low-cost potent remedial tool. On this basis, the scope of this chapter is to extend the base of knowledge on this natural adsorbent, its properties and its application fields. This chapter focuses mainly on the potential utilization of sawdust in the treatment of heavy metals-contaminated wastewater. This would contribute to the development of an entirely commercially viable process of depollution. This chapter compiles the literature on the potential utilization of sawdust as an adsorbent in order to explore its efficiency in removal of toxic metals, offers a discussion of the used surface characterization and pretreatment techniques to improve the sawdust adsorption ability and suggests future research directions for the development of efficient wastewater adsorption processes using this material. [ABSTRACT FROM AUTHOR]

Corrosion prevention of metals like Steel, Aluminum, and Copper is an interesting problem in industries, to solve this problem corrosion inhibitors are one of the most effective applications for metal protection against corrosion in aggressive media. The effect of (2 E)-3-(6-phenylimidazo[2,1- b ][1,3]thiazol-5-yl)-1-(2,4,6-trimethylphenyl)prop-2-en- 1-one (KO38) on the protection of steel, aluminum, and copper in 1 M HCl medium was examined using electrochemical polarization tests to assess inhibition efficiency, also scanning electron microscopy (SEM) to analyze the surface of metals. The maximum protection capacity of KO38 by the method of polarization is between 96% and 97% for the three metals exposed in an acid solution containing 10−4 M. The organic inhibitors can be classified as mixed-type inhibitors since they inhibited both anodic corrosion and cathodic corrosion. The study of the dynamic simulation (DM) helped to visualize the energies of adsorption of the molecule (KO38) on the interfaces of Iron (110), Aluminum (111), and Copper (111), the calculations of quantum chemistry were analyzed by (DFT) at B-3LYP /6–311 G (d, p). The experimental results are in good agreement with the theoretical studies. • One novel organic benzimidazole derivative has been investigated for its anti-corrosive activities. • KO38 show between 96% and 97% corrosion inhibition efficiency at 10−4 M concentrations. • The morphological studies suggest its extraordinary surface adsorption abilities. • The theoretical investigations also support the experimental outcomes. [ABSTRACT FROM AUTHOR]

Heavy-metals water pollution is without doubt a significant environmental problem in the global context. These non-degradable chemical pollutants may be the cause of serious ecological and health issues, due to their ability of penetration and accumulation throughout the food chain exposing humans to slow but certain poisoning. In order to alleviate water stress, several technological solutions for the removal of toxic heavy metals from industrial wastewater have been implemented. The removal efficiency was often limited by the cost-effectiveness, the sludge production and the metal selectivity of the most common physico-chemical processes. Alternatively, adsorption using natural wastes from agricultural and industrial activities is a promising technic that has received great deal of attention recently. It was considered as an economic, efficient, sustainable and green process. Among the used materials, sawdust gained particular interest over other commonly used and was hence extensively reported as a low-cost potent remedial tool. On this basis, the scope of this chapter is to extend the base of knowledge on this natural adsorbent, its properties and its application fields. This chapter focuses mainly on the potential utilization of sawdust in the treatment of heavy metals-contaminated wastewater. This would contribute to the development of an entirely commercially viable process of depollution. This chapter compiles the literature on the potential utilization of sawdust as an adsorbent in order to explore its efficiency in removal of toxic metals, offers a discussion of the used surface characterization and pretreatment techniques to improve the sawdust adsorption ability and suggests future research directions for the development of efficient wastewater adsorption processes using this material. [ABSTRACT FROM AUTHOR]