1. Antibacterial activity of new flavanone glycoside isolated from Tradescantia spathaceaSw.
- Author
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Singh, Kesar, Yadava, R.N., and Yadav, Ritu
- Abstract
AbstractHere we are reporting a new bioactive flavanone glycoside. The compound having molecular formula C21H22O11, melting point 123-125°C, and ESI-MS m/z 451 was isolated from the methanolic extract of Tradescantia SpathaceaSw. Its characterization and structure elucidation was done with the help of various chemical degradation, color reactions, and spectral data like UV-Visible, FT-IR, electrospray ionization mass spectrometry technique, nuclear magnetic resonance spectroscopy, etc. It was recognized as 5,7,3’4’-tetrahydroxy flavanone 3’-O-D-mannopyranoside. This study was also designed to examine the efficacy of an isolated compound against various bacteria which are responsible for food spoilage and pathogens in humans. The organic flavanone glycoside of methanolic extract exhibited a promising antibacterial activity towards Escherichia coli(gram negative) MTCC 724, Bacillus subtilis MTCC 441, Staphylococcus aureusMTCC 737, Pseudomonas aerugenosaMTCC 424, and Salmonella typhimuriumMTCC 3224. A new flavanone glycoside possesses potent anti-bacterial activity so it can be utilized as a potent source of antibacterial agents for food and pharmaceutical interest.
- Published
- 2023
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