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1. Cooccurrence of Predominant Panton-Valentine Leukocidin-Positive Sequence Type (ST) 152 and Multidrug-Resistant ST 241 Staphylococcus aureusClones in Nigerian Hospitals

Author

Okon, Kenneth O., Basset, Patrick, Uba, Auwalu, Lin, Johnson, Oyawoye, Bukola, Shittu, Adebayo O., and Blanc, Dominique S.

Abstract

ABSTRACTNinety-six clinical isolates of Staphylococcus aureusfrom Nigeria were characterized phenotypically and genetically. Twelve multidrug-resistant methicillin (meticillin)-resistant S. aureus(MRSA) isolates carrying a new staphylococcal cassette chromosome mecelement and a high proportion of Panton-Valentine leukocidin (PVL)-positive methicillin-susceptible S. aureus(MSSA) isolates were observed. The cooccurrence of multidrug-resistant MRSA and PVL-positive MSSA isolates entails the risk of emergence of a multidrug-resistant PVL-positive MRSA clone.

Published
2009
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