1,043 results on '"Serban, A."'
Search Results
2. Biomarkers to predict improvement of left ventricular ejection fraction after atrial fibrillation ablation.
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Serban, Teodor, Hennings, Elisa, Strebel, Ivo, Knecht, Sven, du Fay de Lavallaz, Jeanne, Krisai, Philipp, Arnet, Rebecca, Völlmin, Gian, Osswald, Stefan, Sticherling, Christian, Kühne, Michael, and Badertscher, Patrick
- Abstract
Atrial fibrillation (AF) and heart failure frequently coexist. Prediction of left ventricular ejection fraction (LVEF) recovery after catheter ablation (CA) for AF remains difficult. The purpose of this study was to evaluate the value of biomarkers, alone and in combination with the Antwerp score, to predict LVEF recovery after CA for AF. Patients undergoing CA for AF with depressed LVEF (<50%) were included. Plasma levels of 13 biomarkers were measured immediately before CA. Patients were categorized into "responders" and "nonresponders" in a similar fashion to the Antwerp score performance derivation and validation cohorts. The predictive power of the biomarkers alone and combined in outcome prediction was evaluated. A total of 208 patients with depressed LVEF were included (median age 63 years; 39–19% female; median indexed left atrial volume 42 (33–52) mL/m
2 ; median LVEF 43 (38–46)%). At a median follow-up time of 30 (20–34) months, 161 (77%) were responders and 47 (23%) were nonresponders. Of 13 biomarkers, –4—angiopoietin 2 (ANG2), growth differentiation factor 15 (GDF15), fibroblast growth factor 23, and myosin binding protein C3—were significantly different between responders and nonresponders (P ≤.001) and their combination could predict the end point with an area under the curve of 0.72 (95% confidence interval [CI] 0.64–0.81) overall, 0.69 (95% CI 0.59–0.78) in heart failure with mildly reduced ejection fraction, and 0.88 (95% CI 0.77–0.98) in heart failure with reduced ejection fraction. Only ANG2 and GDF15 remained significantly associated with LVEF recovery after adjustment for age, sex, and Antwerp score and significantly improved the accuracy of the Antwerp score predictions (P <.001). The area under the curve of the Antwerp score in the outcome prediction improved from 0.75 (95% CI 0.67–0.83) to 0.78 (95% CI 0.70–0.86). A biomarker panel (ANG2 and GDF15) significantly improved the accuracy of the Antwerp score. [Display omitted] [ABSTRACT FROM AUTHOR]- Published
- 2024
- Full Text
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3. Shear-Wave Elastography of the Achilles tendon: reliability analysis and impact of parameters modulating elasticity values.
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Pelea, Michael-Andrei, Serban, Oana, Badarinza, Maria, Gutiu, Roxana, and Fodor, Daniela
- Abstract
Purpose: Shear wave elastography (SWE) has seen many advancements in Achilles tendon evaluation in recent years, yet standardization of this technique is still problematic due to the lack of knowledge regarding the optimal way to perform the examination. The purpose of this study was to evaluate the effects of ankle position, probe frequency and physical effort on the shear modulus of the Achilles tendon, but also to determine the intra and inter-observer reliability of the technique. Methods: 37 healthy volunteers were included; SWE protocol was performed by two examiners. We analyzed the shear modulus of the tendon with the ankle in neutral, maximum dorsiflexion and maximum plantar flexion using two different high frequency probes. Afterwards, the subjects performed a brief physical exercise and SWE measurements were repeated. Results: The L18-5 probe showed the highest ICC values (ICC = 0.798, 95% CI 0.660–0.880, p < 0.001) when positioned at 2 cm from the calcaneal insertion with the ankle in a neutral state. Conversely, utilizing the same L18-5 probe at 1 cm from the insertion during maximum plantar flexion of the ankle resulted in the lowest ICC (ICC = 0.422, 95% CI 0.032–0.655, p = 0.019). Significant variations in elasticity values were noted among different ankle positions and probe types, while no significant changes in elasticity were observed post-physical exercise. Conclusion: Ankle position and probe frequency are factors that influence elasticity values of the Achilles tendon. An ankle position between 10 and 20 degrees of plantar flexion is the most suitable for SWE evaluation. However, more research focusing on Achilles tendon SWE is essential due to the challenges encountered in standardizing this region. [ABSTRACT FROM AUTHOR]
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- 2024
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4. "It's not just teaching for the sake of teaching anymore": a quality improvement project for online instruction in a hospital library.
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Anderson, Melanie, Nault, Caleb, and Serban, Raluca
- Abstract
Medical libraries had to swiftly change how instruction services were provided in response to the COVID-19 pandemic. This article describes a Quality Improvement (QI) project to assess one hospital library's move to virtual instructional services. Information was gathered via a survey to Canadian hospital library workers and a focus group with internal staff with instructional responsibilities. Moving to online instruction increased audience attendance and garnered positive feedback, however library instructors report experiencing uncertainty about quality and effectiveness of online instruction. The article concludes with a description of planned actions to improve online instructional services in an urban research and teaching hospital library environment. [ABSTRACT FROM AUTHOR]
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- 2024
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5. Metal Affinity Fusion Enzyme Immobilization: Batch Process Showcase for Cascading Alcohol Oxidation and Bayer–Villiger Oxidation in Microaqueous Media.
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Vernet, Guillem, Ma, Yu, Serban, Simona, Basso, Alessandra, Zhang, Ningning, and Kara, Selin
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- 2024
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6. Pilot, open-label, randomized controlled clinical trial evaluating 4 oral hygiene regimens using a manual toothbrush, toothpaste, and mouthwash.
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Rosu, Serban, Benatti, Paola, Bianco, Salvatore, Franco Barattini, Dionisio, Nobile, Vincenzo, Mellai, Marta, and Cattaneo, Dario
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DATA analysis ,PATIENT safety ,RESEARCH funding ,STATISTICAL sampling ,PILOT projects ,PREBIOTICS ,ORAL hygiene ,RANDOMIZED controlled trials ,HUMAN microbiota ,DESCRIPTIVE statistics ,TREATMENT effectiveness ,LONGITUDINAL method ,TOOTHBRUSHES ,DENTIFRICES ,LACTOBACILLUS ,STATISTICS ,DENTAL plaque ,PATIENT satisfaction ,GINGIVAL hyperplasia ,MOUTHWASHES - Abstract
In this prospective pilot study, 84 patients with a history of poor oral hygiene were enrolled in an open-label, interventional, randomized controlled clinical trial. The aim was to provide preliminary clinical data on a new line of oral hygiene products containing a prebiotic and a paraprobiotic based on Lactobacillus plantarum. The recruitment rate and patient satisfaction were analyzed to estimate resources for the future primary study, and descriptive data on rebalancing of the oral microbiota were collected. The population was divided into 5 groups based on the products assigned to the patients: 1, delicate mint toothpaste (n = 20); 2, mint toothpaste (n = 12); 3, mint mouthwash (n = 20); 4, delicate mint toothpaste, mint mouthwash, and an antimicrobial toothbrush (n = 20): and 5, continued use of their usual oral care products and routine (control group; n = 12). The study duration was 28 days. All patients tolerated the products well, and there were no adverse events. The recruitment capability and procedures allowed for a realistic estimation for the future main trial. The products did not cause any changes in tooth color. The participants in group 4, who completed the treatment consisting of delicate mint toothpaste, mint mouthwash, and an antimicrobial toothbrush, reported the greatest reduction in gingival sensitivity (P ≤ 0.000; Wilcoxon signed rank test). Analysis with the Wilcoxon signed rank test revealed that all products induced a statistically significant decrease in plague (P ≤ 0.002) and a reduction in gingival sensitivity (delicate mint toothpaste, P ≤ 0.005; mint toothpaste, P ≤ 0.015; and mint mouthwash, P 5 0.015). All products were effective in stabilizing the oral microbiota. The tested products showed an optimal safety profile and a statistically significant efficacy in reducing gingival sensitivity and plague. They also stabilized the biodiversity of the oral microbiota, making it less susceptible to microbial fluctuations than the control group. Trial registration: ClinicalTrials.gov (NCT05999175). [ABSTRACT FROM AUTHOR]
- Published
- 2024
7. A Synopsis of Biomarkers in Glioblastoma: Past and Present.
- Author
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Tataranu, Ligia Gabriela, Turliuc, Serban, Rizea, Radu Eugen, Dricu, Anica, Alexandru, Oana, Staicu, Georgiana-Adeline, and Kamel, Amira
- Published
- 2024
- Full Text
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8. Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021
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Schumacher, Austin E, Kyu, Hmwe Hmwe, Aali, Amirali, Abbafati, Cristiana, Abbas, Jaffar, Abbasgholizadeh, Rouzbeh, Abbasi, Madineh Akram, Abbasian, Mohammadreza, Abd ElHafeez, Samar, Abdelmasseh, Michael, Abd-Elsalam, Sherief, Abdelwahab, Ahmed, Abdollahi, Mohammad, Abdoun, Meriem, Abdullahi, Auwal, Abdurehman, Ame Mehadi, Abebe, Mesfin, Abedi, Aidin, Abedi, Armita, Abegaz, Tadesse M, Abeldaño Zuñiga, Roberto Ariel, Abhilash, E S, Abiodun, Olugbenga Olusola, Aboagye, Richard Gyan, Abolhassani, Hassan, Abouzid, Mohamed, Abreu, Lucas Guimarães, Abrha, Woldu Aberhe, Abrigo, Michael R M, Abtahi, Dariush, Abu Rumeileh, Samir, Abu-Rmeileh, Niveen ME, Aburuz, Salahdein, Abu-Zaid, Ahmed, Acuna, Juan Manuel, Adair, Tim, Addo, Isaac Yeboah, Adebayo, Oladimeji M, Adegboye, Oyelola A, Adekanmbi, Victor, Aden, Bashir, Adepoju, Abiola Victor, Adetunji, Charles Oluwaseun, Adeyeoluwa, Temitayo Esther, Adeyomoye, Olorunsola Israel, Adha, Rishan, Adibi, Amin, Adikusuma, Wirawan, Adnani, Qorinah Estiningtyas Sakilah, Adra, Saryia, Afework, Abel, Afolabi, Aanuoluwapo Adeyimika, Afraz, Ali, Afyouni, Shadi, Afzal, Saira, Agasthi, Pradyumna, Aghamiri, Shahin, Agodi, Antonella, Agyemang-Duah, Williams, Ahinkorah, Bright Opoku, Ahmad, Aqeel, Ahmad, Danish, Ahmad, Firdos, Ahmad, Muayyad M, Ahmad, Tauseef, Ahmadi, Keivan, Ahmadzade, Amir Mahmoud, Ahmadzade, Mohadese, Ahmed, Ayman, Ahmed, Haroon, Ahmed, Luai A, Ahmed, Muktar Beshir, Ahmed, Syed Anees, Ajami, Marjan, Aji, Budi, Ajumobi, Olufemi, Akalu, Gizachew Taddesse, Akara, Essona Matatom, Akinosoglou, Karolina, Akkala, Sreelatha, Akyirem, Samuel, Al Hamad, Hanadi, Al Hasan, Syed Mahfuz, Al Homsi, Ammar, Al Qadire, Mohammad, Ala, Moein, Aladelusi, Timothy Olukunle, AL-Ahdal, Tareq Mohammed Ali, Alalalmeh, Samer O, Al-Aly, Ziyad, Alam, Khurshid, Alam, Manjurul, Alam, Zufishan, Al-amer, Rasmieh Mustafa, Alanezi, Fahad Mashhour, Alanzi, Turki M, Albashtawy, Mohammed, AlBataineh, Mohammad T, Aldridge, Robert W, Alemi, Sharifullah, Al-Eyadhy, Ayman, Al-Gheethi, Adel Ali Saeed, Alhabib, Khalid F, Alhalaiqa, Fadwa Alhalaiqa Naji, Al-Hanawi, Mohammed Khaled, Ali, Abid, Ali, Akhtar, Ali, Beriwan Abdulqadir, Ali, Hassam, Ali, Mohammed Usman, Ali, Rafat, Ali, Syed Shujait Shujait, Ali, Zahid, Alian Samakkhah, Shohreh, Alicandro, Gianfranco, Alif, Sheikh Mohammad, Aligol, Mohammad, Alimi, Rasoul, Aliyi, Ahmednur Adem, Al-Jumaily, Adel, Aljunid, Syed Mohamed, Almahmeed, Wael, Al-Marwani, Sabah, Al-Maweri, Sadeq Ali Ali, Almazan, Joseph Uy, Al-Mekhlafi, Hesham M, Almidani, Omar, Alomari, Mahmoud A, Alonso, Nivaldo, Alqahtani, Jaber S, Alqutaibi, Ahmed Yaseen, Al-Sabah, Salman Khalifah, Altaf, Awais, Al-Tawfiq, Jaffar A, Altirkawi, Khalid A, Alvi, Farrukh Jawad, Alwafi, Hassan, Al-Worafi, Yaser Mohammed, Aly, Hany, Alzoubi, Karem H, Amare, Azmeraw T, Ameyaw, Edward Kwabena, Amhare, Abebe Feyissa, Amin, Tarek Tawfik, Amindarolzarbi, Alireza, Aminian Dehkordi, Javad, Amiri, Sohrab, Amu, Hubert, Amugsi, Dickson A, Amzat, Jimoh, Ancuceanu, Robert, Anderlini, Deanna, Andrade, Pedro Prata, Andrei, Catalina Liliana, Andrei, Tudorel, Angappan, Dhanalakshmi, Anil, Abhishek, Anjum, Afifa, Antony, Catherine M, Antriyandarti, Ernoiz, Anuoluwa, Iyadunni Adesola, Anwar, Sumadi Lukman, Anyasodor, Anayochukwu Edward, Appiah, Seth Christopher Yaw, Aqeel, Muhammad, Arabloo, Jalal, Arabzadeh Bahri, Razman, Arab-Zozani, Morteza, Arafat, Mosab, Araújo, Ana Margarida, Aravkin, Aleksandr Y, Aremu, Abdulfatai, Ariffin, Hany, Aripov, Timur, Armocida, Benedetta, Arooj, Mahwish, Artamonov, Anton A, Artanti, Kurnia Dwi, Arulappan, Judie, Aruleba, Idowu Thomas, Aruleba, Raphael Taiwo, Arumugam, Ashokan, Asaad, Malke, Asgary, Saeed, Ashemo, Mubarek Yesse, Ashraf, Muhammad, Asika, Marvellous O, Athari, Seyyed Shamsadin, Atout, Maha Moh'd Wahbi, Atreya, Alok, Attia, Sameh, Aujayeb, Avinash, Avan, Abolfazl, Awotidebe, Adedapo Wasiu, Ayala Quintanilla, Beatriz Paulina, Ayanore, Martin Amogre, Ayele, Getnet Melaku, Ayuso-Mateos, Jose L, Ayyoubzadeh, Seyed Mohammad, Azadnajafabad, Sina, Azhar, Gulrez Shah, Aziz, Shahkaar, Azzam, Ahmed Y, Babashahi, Mina, Babu, Abraham Samuel, Badar, Muhammad, Badawi, Alaa, Badiye, Ashish D, Baghdadi, Soroush, Bagheri, Nasser, Bagherieh, Sara, Bah, Sulaiman, Bahadorikhalili, Saeed, Bai, Jianjun, Bai, Ruhai, Baker, Jennifer L, Bakkannavar, Shankar M, Bako, Abdulaziz T, Balakrishnan, Senthilkumar, Balogun, Saliu A, Baltatu, Ovidiu Constantin, Bam, Kiran, Banach, Maciej, Bandyopadhyay, Soham, Banik, Biswajit, Banik, Palash Chandra, Bansal, Hansi, Barati, Shirin, Barchitta, Martina, Bardhan, Mainak, Barker-Collo, Suzanne Lyn, Barone-Adesi, Francesco, Barqawi, Hiba Jawdat, Barr, Ronald D, Barrero, Lope H, Basharat, Zarrin, Bashir, Asma'u I J, Bashiru, Hameed Akande, Baskaran, Pritish, Basnyat, Buddha, Bassat, Quique, Basso, João Diogo, Basu, Saurav, Batra, Kavita, Batra, Ravi, Baune, Bernhard T, Bayati, Mohsen, Bayileyegn, Nebiyou Simegnew, Beaney, Thomas, Bedi, Neeraj, Begum, Tahmina, Behboudi, Emad, Behnoush, Amir Hossein, Beiranvand, Maryam, Bejarano Ramirez, Diana Fernanda, Belgaumi, Uzma Iqbal, Bell, Michelle L, Bello, Aminu K, Bello, Muhammad Bashir, Bello, Olorunjuwon Omolaja, Belo, Luis, Beloukas, Apostolos, Bendak, Salaheddine, Bennett, Derrick A, Bensenor, Isabela M, Benzian, Habib, Berezvai, Zombor, Berman, Adam E, Bermudez, Amiel Nazer C, Bettencourt, Paulo J G, Beyene, Habtamu B, Beyene, Kebede A, Bhagat, Devidas S, Bhagavathula, Akshaya Srikanth, Bhala, Neeraj, Bhalla, Ashish, Bhandari, Dinesh, Bhardwaj, Nikha, Bhardwaj, Pankaj, Bhardwaj, Prarthna V, Bhargava, Ashish, Bhaskar, Sonu, Bhat, Vivek, Bhatti, Gurjit Kaur, Bhatti, Jasvinder Singh, Bhatti, Manpreet S, Bhatti, Rajbir, Bhutta, Zulfiqar A, Bikbov, Boris, Binmadi, Nada, Bintoro, Bagas Suryo, Biondi, Antonio, Bisignano, Catherine, Bisulli, Francesca, Biswas, Atanu, Biswas, Raaj Kishore, Bitaraf, Saeid, Bjørge, Tone, Bleyer, Archie, Boampong, Mary Sefa, Bodolica, Virginia, Bodunrin, Aadam Olalekan, Bolarinwa, Obasanjo Afolabi, Bonakdar Hashemi, Milad, Bonny, Aime, Bora, Kaustubh, Bora Basara, Berrak, Borodo, Safiya Bala, Borschmann, Rohan, Botero Carvajal, Alejandro, Bouaoud, Souad, Boudalia, Sofiane, Boyko, Edward J, Bragazzi, Nicola Luigi, Braithwaite, Dejana, Brenner, Hermann, Britton, Gabrielle, Browne, Annie J, Brunoni, Andre R, Bulamu, Norma B, Bulto, Lemma N, Buonsenso, Danilo, Burkart, Katrin, Burns, Richard A, Burugina Nagaraja, Sharath, Busse, Reinhard, Bustanji, Yasser, Butt, Zahid A, Caetano dos Santos, Florentino Luciano, Cai, Tianji, Calina, Daniela, Cámera, Luis Alberto, Campos, Luciana Aparecida, Campos-Nonato, Ismael R, Cao, Chao, Cardenas, Carlos Alberto, Cárdenas, Rosario, Carr, Sinclair, Carreras, Giulia, Carrero, Juan J, Carugno, Andrea, Carvalho, Felix, Carvalho, Márcia, Castaldelli-Maia, Joao Mauricio, Castañeda-Orjuela, Carlos A, Castelpietra, Giulio, Catalá-López, Ferrán, Catapano, Alberico L, Cattaruzza, Maria Sofia, Caye, Arthur, Cederroth, Christopher R, Cembranel, Francieli, Cenderadewi, Muthia, Cercy, Kelly M, Cerin, Ester, Cevik, Muge, Chacón-Uscamaita, Pamela R Uscamaita, Chahine, Yaacoub, Chakraborty, Chiranjib, Chan, Jeffrey Shi Kai, Chang, Chin-Kuo, Charalampous, Periklis, Charan, Jaykaran, Chattu, Vijay Kumar, Chatzimavridou-Grigoriadou, Victoria, Chavula, Malizgani Paul, Cheema, Huzaifa Ahmad, Chen, An-Tian, Chen, Haowei, Chen, Lingxiao, Chen, Meng Xuan, Chen, Simiao, Cherbuin, Nicolas, Chew, Derek S, Chi, Gerald, Chirinos-Caceres, Jesus Lorenzo, Chitheer, Abdulaal, Cho, So Mi Jemma, Cho, William C S, Chong, Bryan, Chopra, Hitesh, Choudhary, Rahul, Chowdhury, Rajiv, Chu, Dinh-Toi, Chukwu, Isaac Sunday, Chung, Eric, Chung, Eunice, Chung, Sheng-Chia, Cini, Karly I, Clark, Cain C T, Coberly, Kaleb, Columbus, Alyssa, Comfort, Haley, Conde, Joao, Conti, Sara, Cortesi, Paolo Angelo, Costa, Vera Marisa, Cousin, Ewerton, Cowden, Richard G, Criqui, Michael H, Cruz-Martins, Natália, Culbreth, Garland T, Cullen, Patricia, Cunningham, Matthew, da Silva e Silva, Daniel, Dadana, Sriharsha, Dadras, Omid, Dai, Zhaoli, Dalal, Koustuv, Dalli, Lachlan L, Damiani, Giovanni, D'Amico, Emanuele, Daneshvar, Sara, Darwesh, Aso Mohammad, Das, Jai K, Das, Saswati, Dash, Nihar Ranjan, Dashti, Mohsen, Dávila-Cervantes, Claudio Alberto, Davis Weaver, Nicole, Davletov, Kairat, De Leo, Diego, Debele, Aklilu Tamire, Degenhardt, Louisa, Dehbandi, Reza, Deitesfeld, Lee, Delgado-Enciso, Ivan, Delgado-Ortiz, Laura, Demant, Daniel, Demessa, Berecha Hundessa, Demetriades, Andreas K, Deng, Xinlei, Denova-Gutiérrez, Edgar, Deribe, Kebede, Dervenis, Nikolaos, Des Jarlais, Don C, Desai, Hardik Dineshbhai, Desai, Rupak, Deuba, Keshab, Devanbu, Vinoth Gnana Chellaiyan, Dey, Sourav, Dhali, Arkadeep, Dhama, Kuldeep, Dhimal, Mandira Lamichhane, Dhimal, Meghnath, Dhingra, Sameer, Dias da Silva, Diana, Diaz, Daniel, Dima, Adriana, Ding, Delaney D, Dirac, M Ashworth, Dixit, Abhinav, Dixit, Shilpi Gupta, Do, Thanh Chi, Do, Thao Huynh Phuong, do Prado, Camila Bruneli, Dodangeh, Masoud, Dokova, Klara Georgieva, Dolecek, Christiane, Dorsey, E Ray, dos Santos, Wendel Mombaque, Doshi, Rajkumar, Doshmangir, Leila, Douiri, Abdel, Dowou, Robert Kokou, Driscoll, Tim Robert, Dsouza, Haneil Larson, Dube, John, Dumith, Samuel C, Dunachie, Susanna J, Duncan, Bruce B, Duraes, Andre Rodrigues, Duraisamy, Senbagam, Durojaiye, Oyewole Christopher, Dutta, Sulagna, Dzianach, Paulina Agnieszka, Dziedzic, Arkadiusz Marian, Ebenezer, Oluwakemi, Eboreime, Ejemai, Ebrahimi, Alireza, Echieh, Chidiebere Peter, Ed-Dra, Abdelaziz, Edinur, Hisham Atan, Edvardsson, David, Edvardsson, Kristina, Efendi, Defi, Efendi, Ferry, Eghdami, Shayan, Eikemo, Terje Andreas, Eini, Ebrahim, Ekholuenetale, Michael, Ekpor, Emmanuel, Ekundayo, Temitope Cyrus, El Arab, Rabie Adel, El Morsi, Doaa Abdel Wahab, El Sayed Zaki, Maysaa, El Tantawi, Maha, Elbarazi, Iffat, Elemam, Noha Mousaad, Elgar, Frank J, Elgendy, Islam Y, ElGohary, Ghada Metwally Tawfik, Elhabashy, Hala Rashad, Elhadi, Muhammed, Elmeligy, Omar Abdelsadek Abdou, Elshaer, Mohammed, Elsohaby, Ibrahim, Emami Zeydi, Amir, Emamverdi, Mehdi, Emeto, Theophilus I, Engelbert Bain, Luchuo, Erkhembayar, Ryenchindorj, Eshetie, Tesfahun C, Eskandarieh, Sharareh, Espinosa-Montero, Juan, Estep, Kara, Etaee, Farshid, Eze, Ugochukwu Anthony, Fabin, Natalia, Fadaka, Adewale Oluwaseun, Fagbamigbe, Adeniyi Francis, Fahimi, Saman, Falzone, Luca, Farinha, Carla Sofia e Sá, Faris, MoezAlIslam Ezzat Mahmoud, Farjoud Kouhanjani, Mohsen, Faro, Andre, Farrokhpour, Hossein, Fatehizadeh, Ali, Fattahi, Hamed, Fauk, Nelsensius Klau, Fazeli, Pooria, Feigin, Valery L, Fekadu, Ginenus, Fereshtehnejad, Seyed-Mohammad, Feroze, Abdullah Hamid, Ferrante, Daniela, Ferrara, Pietro, Ferreira, Nuno, Fetensa, Getahun, Filip, Irina, Fischer, Florian, Flavel, Joanne, Flaxman, Abraham D, Flor, Luisa S, Florin, Bobirca Teodor, Folayan, Morenike Oluwatoyin, Foley, Kristen Marie, Fomenkov, Artem Alekseevich, Force, Lisa M, Fornari, Carla, Foroutan, Behzad, Foschi, Matteo, Francis, Kate Louise, Franklin, Richard Charles, Freitas, Alberto, Friedman, Joseph, Friedman, Sara D, Fukumoto, Takeshi, Fuller, John E, Gaal, Peter Andras, Gadanya, Muktar A, Gaihre, Santosh, Gaipov, Abduzhappar, Gakidou, Emmanuela, Galali, Yaseen, Galehdar, Nasrin, Gallus, Silvano, Gan, Quan, Gandhi, Aravind P, Ganesan, Balasankar, Garg, Jalaj, Gau, Shuo-Yan, Gautam, Prem, Gautam, Rupesh K, Gazzelloni, Federica, Gebregergis, Miglas W, Gebrehiwot, Mesfin, Gebremariam, Tesfay Brhane, Gerema, Urge, Getachew, Motuma Erena, Getachew, Tamirat, Gething, Peter W, Ghafourifard, Mansour, Ghahramani, Sulmaz, Ghailan, Khalid Yaser, Ghajar, Alireza, Ghanbarnia, Mohammad Javad, Ghasemi, MohammadReza, Ghasemzadeh, Afsaneh, Ghassemi, Fariba, Ghazy, Ramy Mohamed, Ghimire, Sailaja, Gholamian, Asadollah, Gholamrezanezhad, Ali, Ghorbani Vajargah, Pooyan, Ghozali, Ghozali, Ghozy, Sherief, Ghuge, Arun Digambarrao, Gialluisi, Alessandro, Gibson, Ruth Margaret, Gil, Artyom Urievich, Gill, Paramjit Singh, Gill, Tiffany K, Gillum, Richard F, Ginindza, Themba G, Girmay, Alem, Glasbey, James C, Gnedovskaya, Elena V, Göbölös, Laszlo, Goel, Amit, Goldust, Mohamad, Golechha, Mahaveer, Goleij, Pouya, Golestanfar, Arefeh, Golinelli, Davide, Gona, Philimon N, Goudarzi, Houman, Goudarzian, Amir Hossein, Goyal, Anmol, Greenhalgh, Scott, Grivna, Michal, Guarducci, Giovanni, Gubari, Mohammed Ibrahim Mohialdeen, Gudeta, Mesay Dechasa, Guha, Avirup, Guicciardi, Stefano, Gunawardane, Damitha Asanga, Gunturu, Sasidhar, Guo, Cui, Gupta, Anish Kumar, Gupta, Bhawna, Gupta, Indarchand Ratanlal, Gupta, Rajat Das, Gupta, Sapna, Gupta, Veer Bala, Gupta, Vijai Kumar, Gupta, Vivek Kumar, Gutiérrez, Reyna Alma, Habibzadeh, Farrokh, Habibzadeh, Parham, Hachinski, Vladimir, Haddadi, Mohammad, Haddadi, Rasool, Haep, Nils, Hajj Ali, Adel, Halboub, Esam S, Halim, Sobia Ahsan, Hall, Brian J, Haller, Sebastian, Halwani, Rabih, Hamadeh, Randah R, Hamagharib Abdullah, Kanaan, Hamidi, Samer, Hamiduzzaman, Mohammad, Hammoud, Ahmad, Hanifi, Nasrin, Hankey, Graeme J, Hannan, Md Abdul, Haque, Md Nuruzzaman, Harapan, Harapan, Haro, Josep Maria, Hasaballah, Ahmed I, Hasan, Faizul, Hasan, Ikramul, Hasan, M Tasdik, Hasani, Hamidreza, Hasanian, Mohammad, Hasanpour- Dehkordi, Ali, Hassan, Abbas M, Hassan, Amr, Hassanian-Moghaddam, Hossein, Hassanipour, Soheil, Haubold, Johannes, Havmoeller, Rasmus J, Hay, Simon I, Hbid, Youssef, Hebert, Jeffrey J, Hegazi, Omar E, Heidari, Golnaz, Heidari, Mohammad, Heidari-Foroozan, Mahsa, Heidari-Soureshjani, Reza, Helfer, Bartosz, Herteliu, Claudiu, Hesami, Hamed, Hettiarachchi, Dineshani, Heyi, Demisu Zenbaba, Hezam, Kamal, Hiraike, Yuta, Hoffman, Howard J, Holla, Ramesh, Horita, Nobuyuki, Hossain, Md Belal, Hossain, Md Mahbub, Hossain, Sahadat, Hosseini, Mohammad-Salar, Hosseinzadeh, Hassan, Hosseinzadeh, Mehdi, Hostiuc, Mihaela, Hostiuc, Sorin, Hsairi, Mohamed, Hsieh, Vivian Chia-rong, Hu, Chengxi, Huang, Junjie, Huda, Md Nazmul, Hugo, Fernando 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- Abstract
Estimates of demographic metrics are crucial to assess levels and trends of population health outcomes. The profound impact of the COVID-19 pandemic on populations worldwide has underscored the need for timely estimates to understand this unprecedented event within the context of long-term population health trends. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 provides new demographic estimates for 204 countries and territories and 811 additional subnational locations from 1950 to 2021, with a particular emphasis on changes in mortality and life expectancy that occurred during the 2020–21 COVID-19 pandemic period.
- Published
- 2024
- Full Text
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9. Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
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Shams-Beyranvand, Mehran, Shamshad, Hina, Shamsi, Mohammad Anas, Shanawaz, Mohd, Shankar, Abhishek, Sharfaei, Sadaf, Sharifan, Amin, Sharifi-Rad, Javad, Sharma, Rajesh, Sharma, Saurab, Sharma, Ujjawal, Sharma, Vishal, Shastry, Rajesh P, Shavandi, Amin, Shayan, Maryam, Shehabeldine, Amr Mohamed Elsayed, Sheikh, Aziz, Sheikhi, Rahim Ali, Shen, Jiabin, Shetty, Adithi, Shetty, B Suresh Kumar, Shetty, Pavanchand H, Shi, Peilin, Shibuya, Kenji, Shiferaw, Desalegn, Shigematsu, Mika, Shin, Min-Jeong, Shin, Youn Ho, Shiri, Rahman, Shirkoohi, Reza, Shitaye, Nebiyu Aniley, Shittu, Aminu, Shiue, Ivy, Shivakumar, K M, Shivarov, Velizar, Shokraneh, Farhad, Shokri, Azad, Shool, Sina, Shorofi, Seyed Afshin, Shrestha, Sunil, Shuval, Kerem, Siddig, Emmanuel Edwar, Silva, João Pedro, Silva, Luís Manuel Lopes Rodrigues, Silva, Soraia, Simpson, Colin R, Singal, Anjali, Singh, Abhinav, Singh, Balbir Bagicha, Singh, Garima, Singh, Jasbir, Singh, Narinder Pal, Singh, Paramdeep, Singh, Surjit, Sinha, Dhirendra 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Mindy D, Szócska, Miklós, Tabaee Damavandi, Payam, Tabarés-Seisdedos, Rafael, Tabatabaei, Seyyed Mohammad, Tabatabaei Malazy, Ozra, Tabatabaeizadeh, Seyed-Amir, Tabatabai, Shima, Tabish, Mohammad, TADAKAMADLA, JYOTHI, Tadakamadla, Santosh Kumar, Taheri Abkenar, Yasaman, Taheri Soodejani, Moslem, Taiba, Jabeen, Takahashi, Ken, Talaat, Iman M, Talukder, Ashis, Tampa, Mircea, Tamuzi, Jacques Lukenze, Tan, Ker-Kan, Tandukar, Sarmila, Tang, Haosu, Tang, Hong K, Tarigan, Ingan Ukur, Tariku, Mengistie Kassahun, Tariqujjaman, Md, Tarkang, Elvis Enowbeyang, Tavakoli Oliaee, Razieh, Tavangar, Seyed Mohammad, Taveira, Nuno, Tefera, Yibekal Manaye, Temsah, Mohamad-Hani, Temsah, Reem Mohamad Hani, Teramoto, Masayuki, Tesler, Riki, Teye-Kwadjo, Enoch, Thakur, Rishu, Thangaraju, Pugazhenthan, Thankappan, Kavumpurathu Raman, Tharwat, Samar, Thayakaran, Rasiah, Thomas, Nihal, Thomas, Nikhil Kenny, Thomson, Azalea M, Thrift, Amanda G, Thum, Chern Choong Chern, Thygesen, Lau Caspar, Tian, Jing, Tichopad, 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Zhi-Jiang, Zhao, Hanqing, Zhong, Chenwen, Zhou, Juexiao, Zhu, Bin, Zhu, Lei, Ziafati, Makan, Zielińska, Magdalena, Zitoun, Osama A, Zoladl, Mohammad, Zou, Zhiyong, Zuhlke, Liesl J, Zumla, Alimuddin, Zweck, Elric, Zyoud, Samer H, Wool, Eve E, and Murray, Christopher J L
- Abstract
Regular, detailed reporting on population health by underlying cause of death is fundamental for public health decision making. Cause-specific estimates of mortality and the subsequent effects on life expectancy worldwide are valuable metrics to gauge progress in reducing mortality rates. These estimates are particularly important following large-scale mortality spikes, such as the COVID-19 pandemic. When systematically analysed, mortality rates and life expectancy allow comparisons of the consequences of causes of death globally and over time, providing a nuanced understanding of the effect of these causes on global populations.
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- 2024
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10. The Association of Intra-Abdominal Adhesions with Peritoneal Dialysis Catheter-Related Complications
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Qureshi, Mohammad Azfar, Maierean, Serban, Crabtree, John H., Clarke, Alix, Armstrong, Sean, Fissell, Rachel, Jain, Arsh K., Jassal, Sarbjit V., Hu, Susie L., Kennealey, Peter, Liebman, Scott, McCormick, Brendan, Momciu, Bogdan, Pauly, Robert P., Pellegrino, Beth, Perl, Jeffrey, Pirkle, James L., Plumb, Troy J., Seshasai, Rebecca, Shah, Ankur, Shah, Nikhil, Shen, Jenny, Singh, Gurmukteshwar, Tennankore, Karthik, Uribarri, Jaime, Vasilevsky, Murray, Yang, Robert, Quinn, Robert R., Nadler, Ashlie, Oliver, Matthew J., Maierean, Serban, Crabtree, John H., Clarke, Alix, Armstrong, Sean, Fissell, Rachel, Jain, Arsh K., Jassal, Sarbjit V., Hu, Susie L., Kennealey, Peter, Liebman, Scott, McCormick, Brendan, Momciu, Bogdan, Pauly, Robert P., Pellegrino, Beth, Perl, Jeffrey, Pirkle, James L., Plumb, Troy J., Seshasai, Rebecca, Shah, Ankur, Shah, Nikhil, Shen, Jenny, Singh, Gurmukteshwar, Tennankore, Karthik, Uribarri, Jaime, Vasilevsky, Murray, Yang, Robert, Quinn, Robert R., and Oliver, Matthew J.
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- 2024
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11. Status of the ELT phasing and diagnostic station project
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Egner, Sébastien E., Roberts, Scott, Pettazzi, Lorenzo, Pfrommer, Thomas, Lewis, Steffan, Abad, Jose Antonio, Araujo Hauck, Constanza, Bedigan, Helen, Bonnet, Henri, Bourget, Pierre, Brinkmann, Martin, Calmette, Elsa, Cortes, Angela, Engler, Byron, Frank, Christoph, Gago, Fernando, Grudzien, Thomas, Guidolin, Ivan Maria, Haimerl, Andreas, Hammersley, Peter, Haug, Marcus, Hinterschuster, Renate, Huber, Stefan, Jolley, Paul, Kellerer, Aglae, Kiekebusch, Mario, Kirchbauer, Jean-Paul, Kolmeder, Johannes, Kosmalski, Johan, Lampater, Ulrich, La Penna, Paolo, Leveratto, Serban, Lucuix, Christian, Lopez Gil, Ignacio, Mandla, Christopher, Marchetti, Enrico, Moins, Christophe, Paufique, Jerome, Pfuhl, Oliver, Popovic, Dan, Sedghi, Babak, Tordo, Sebastien, Verinaud, Christophe, and Zuluaga, Pablo
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- 2024
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12. Toward real-time reporting of cancer incidence: methodology, pilot study, and SEER Program implementation
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Chen, Huann-Sheng, Negoita, Serban, Schwartz, Steve, Hsu, Elizabeth, Hafterson, Jennifer, Coyle, Linda, Stevens, Jennifer, Fernandez, Anna, Potts, Mary, and Feuer, Eric J
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- 2024
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13. History of the Surveillance, Epidemiology, and End Results (SEER) Program
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Friedman, Steve and Negoita, Serban
- Abstract
The Surveillance, Epidemiology, and End Results (SEER) Program established in 1973 was the first laboratory for experimenting with new methods for cancer data collection and translating the data into population-based cancer statistics. The SEER Program staff have been instrumental in the development of the International Classification of Disease-Oncologyand successfully implemented the routine collection of anatomic and prognostic cancer stage at diagnosis. Currently the program consists of 21 central registries that generate cancer statistics covering more than 48% of the US population and an additional 10 research support registries contributing to certain research projects, such as the National Childhood Cancer Registry.In parallel with the geographical expansion, the program built an architecture of methods and tools for population-based cancer statistics, with SEER*Explorer as the most recent online tool for descriptive statistics. In addition, SEER releases annual updates for a comprehensive data product line, which includes SEER*Stat databases with an annual caseload of more than 800 000 incident cases. Furthermore, the program developed a full suite of analytical applications for population-based cancer statistics that include Joinpoint (regression-based trend analysis), DevCan (risk of diagnosis and death), CanSurv (survival models), and ComPrev and PrejPrev (cancer prevalence), among others.The future of the SEER Program is closely aligned to the overall goals of the “war on cancer.” The program aims to release longitudinal treatment data coupled with a comprehensive genomic characterization of cancers with a declared goal of decreasing the cancer burden and disparities across a wide spectrum of diseases and communities.
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- 2024
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14. Reporting tumor genomic test results to SEER registries via linkages
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Petkov, Valentina I, Byun, Jung S, Ward, Kevin C, Schussler, Nicola C, Archer, Natalie P, Bentler, Suzanne, Doherty, Jennifer A, Durbin, Eric B, Gershman, Susan T, Cheng, Iona, Insaf, Tabassum, Gonsalves, Lou, Hernandez, Brenda Y, Koch, Lori, Liu, Lihua, Monnereau, Alain, Morawski, Bozena M, Schwartz, Stephen M, Stroup, Antoinette, Wiggins, Charles, Wu, Xiao-Cheng, Bonds, Sarah, Negoita, Serban, and Penberthy, Lynne
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- 2024
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15. The Molecular Detection of Germline Mutations in the BRCA1 and BRCA2 Genes Associated with Breast and Ovarian Cancer in a Romanian Cohort of 616 Patients.
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Grigore, Liliana-Georgiana, Radoi, Viorica-Elena, Serban, Alexandra, Mihai, Adina Daniela, and Stoica, Ileana
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- 2024
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16. Characterizing phenotypic data of Peromyscus leucopuscompared to C57BL/6J Mus musculusand diversity outbred (DO) Mus musculus
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Wimer, Lauren A., Davis-Castillo, Asia, Galkina, Sofiya, Ciotlos, Serban, Patterson, Cavan, Prado, Leandro, Munoz, Maria Castro, Martin, Nicolas, Epstein, Sharon, Schaum, Nicholas, and Melov, Simon
- Abstract
Translational research is commonly performed in the C57B6/J mouse strain, chosen for its genetic homogeneity and phenotypic uniformity. Here, we evaluate the suitability of the white-footed deer mouse (Peromyscus leucopus) as a model organism for aging research, offering a comparative analysis against C57B6/J and diversity outbred (DO) Mus musculusstrains. Our study includes comparisons of body composition, skeletal muscle function, and cardiovascular parameters, shedding light on potential applications and limitations of P. leucopusin aging studies. Notably, P. leucopusexhibits distinct body composition characteristics, emphasizing reduced muscle force exertion and a unique metabolism, particularly in fat mass. Cardiovascular assessments showed changes in arterial stiffness, challenging conventional assumptions and highlighting the need for a nuanced interpretation of aging-related phenotypes. Our study also highlights inherent challenges associated with maintaining and phenotyping P. leucopuscohorts. Behavioral considerations, including anxiety-induced responses during handling and phenotyping assessment, pose obstacles in acquiring meaningful data. Moreover, the unique anatomy of P. leucopusnecessitates careful adaptation of protocols designed for Mus musculus. While showcasing potential benefits, further extensive analyses across broader age ranges and larger cohorts are necessary to establish the reliability of P. leucopusas a robust and translatable model for aging studies.
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- 2024
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17. Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
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Brauer, Michael, Roth, Gregory A, Aravkin, Aleksandr Y, Zheng, Peng, Abate, Kalkidan Hassen, Abate, Yohannes Habtegiorgis, Abbafati, Cristiana, Abbasgholizadeh, Rouzbeh, Abbasi, Madineh Akram, Abbasian, Mohammadreza, Abbasifard, Mitra, Abbasi-Kangevari, Mohsen, Abd ElHafeez, Samar, Abd-Elsalam, Sherief, Abdi, Parsa, Abdollahi, Mohammad, Abdoun, Meriem, Abdulah, Deldar Morad, Abdullahi, Auwal, Abebe, Mesfin, Abedi, Aidin, Abedi, Armita, Abegaz, Tadesse M, Abeldaño Zuñiga, Roberto Ariel, Abiodun, Olumide, Abiso, Temesgen Lera, Aboagye, Richard Gyan, Abolhassani, Hassan, Abouzid, Mohamed, Aboye, Girma Beressa, Abreu, Lucas Guimarães, Abualruz, Hasan, Abubakar, Bilyaminu, Abu-Gharbieh, Eman, Abukhadijah, Hana Jihad Jihad, Aburuz, Salahdein, Abu-Zaid, Ahmed, Adane, Mesafint Molla, Addo, Isaac Yeboah, Addolorato, Giovanni, Adedoyin, Rufus Adesoji, Adekanmbi, Victor, Aden, Bashir, Adetunji, Juliana Bunmi, Adeyeoluwa, Temitayo Esther, Adha, Rishan, Adibi, Amin, Adnani, Qorinah Estiningtyas Sakilah, Adzigbli, Leticia Akua, Afolabi, Aanuoluwapo Adeyimika, Afolabi, Rotimi Felix, Afshin, Ashkan, Afyouni, Shadi, Afzal, Muhammad Sohail, Afzal, Saira, Agampodi, Suneth Buddhika, Agbozo, Faith, Aghamiri, Shahin, Agodi, Antonella, Agrawal, Anurag, Agyemang-Duah, Williams, Ahinkorah, Bright Opoku, Ahmad, Aqeel, Ahmad, Danish, Ahmad, Firdos, Ahmad, Noah, Ahmad, Shahzaib, Ahmad, Tauseef, Ahmed, Ali, Ahmed, Anisuddin, Ahmed, Ayman, Ahmed, Luai A, Ahmed, Muktar Beshir, Ahmed, Safoora, Ahmed, Syed Anees, Ajami, Marjan, Akalu, Gizachew Taddesse, Akara, Essona Matatom, Akbarialiabad, Hossein, Akhlaghi, Shiva, Akinosoglou, Karolina, Akinyemiju, Tomi, Akkaif, Mohammed Ahmed, Akkala, Sreelatha, Akombi-Inyang, Blessing, Al Awaidy, Salah, Al Hasan, Syed Mahfuz, Alahdab, Fares, AL-Ahdal, Tareq Mohammed Ali, Alalalmeh, Samer O, Alalwan, Tariq A, Al-Aly, Ziyad, Alam, Khurshid, Alam, Nazmul, Alanezi, Fahad Mashhour, Alanzi, Turki M, Albakri, Almaza, AlBataineh, Mohammad T, Aldhaleei, Wafa A, Aldridge, Robert W, Alemayohu, Mulubirhan Assefa, Alemu, Yihun Mulugeta, Al-Fatly, Bassam, Al-Gheethi, Adel Ali Saeed, Al-Habbal, Khairat, Alhabib, Khalid F, Alhassan, Robert Kaba, Ali, Abid, Ali, Amjad, Ali, Beriwan Abdulqadir, Ali, Iman, Ali, Liaqat, Ali, Mohammed Usman, Ali, Rafat, Ali, Syed Shujait Shujait, Ali, Waad, Alicandro, Gianfranco, Alif, Sheikh Mohammad, Aljunid, Syed Mohamed, Alla, François, Al-Marwani, Sabah, Al-Mekhlafi, Hesham M, Almustanyir, Sami, Alomari, Mahmoud A, Alonso, Jordi, Alqahtani, Jaber S, Alqutaibi, Ahmed Yaseen, Al-Raddadi, Rajaa M, Alrawashdeh, Ahmad, Al-Rifai, Rami Hani, Alrousan, Sahel Majed, Al-Sabah, Salman Khalifah, Alshahrani, Najim Z, Altaany, Zaid, Altaf, Awais, Al-Tawfiq, Jaffar A, Altirkawi, Khalid A, Aluh, Deborah Oyine, Alvis-Guzman, Nelson, Alvis-Zakzuk, Nelson J, Alwafi, Hassan, Al-Wardat, Mohammad Sami, Al-Worafi, Yaser Mohammed, Aly, Hany, Aly, Safwat, Alzoubi, Karem H, Al-Zyoud, Walid, Amaechi, Uchenna Anderson, Aman Mohammadi, Masous, Amani, Reza, Amiri, Sohrab, Amirzade-Iranaq, Mohammad Hosein, Ammirati, Enrico, Amu, Hubert, Amugsi, Dickson A, Amusa, Ganiyu Adeniyi, Ancuceanu, Robert, Anderlini, Deanna, Anderson, Jason A, Andrade, Pedro Prata, Andrei, Catalina Liliana, Andrei, Tudorel, Anenberg, Susan C, Angappan, Dhanalakshmi, Angus, Colin, Anil, Abhishek, Anil, Sneha, Anjum, Afifa, Anoushiravani, Amir, Antonazzo, Ippazio Cosimo, Antony, Catherine M, Antriyandarti, Ernoiz, Anuoluwa, Boluwatife Stephen, Anvari, Davood, Anvari, Saeid, Anwar, Saleha, Anwar, Sumadi Lukman, Anwer, Razique, Anyabolo, Ekenedilichukwu Emmanuel, Anyasodor, Anayochukwu Edward, Apostol, Geminn Louis Carace, Arabloo, Jalal, Arabzadeh Bahri, Razman, Arafat, Mosab, Areda, Demelash, Aregawi, Brhane Berhe, Aremu, Abdulfatai, Armocida, Benedetta, Arndt, Michael Benjamin, Ärnlöv, Johan, Arooj, Mahwish, Artamonov, Anton A, Artanti, Kurnia Dwi, Aruleba, Idowu Thomas, Arumugam, Ashokan, Asbeutah, Akram M, Asgary, Saeed, Asgedom, Akeza Awealom, 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- Abstract
Understanding the health consequences associated with exposure to risk factors is necessary to inform public health policy and practice. To systematically quantify the contributions of risk factor exposures to specific health outcomes, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 aims to provide comprehensive estimates of exposure levels, relative health risks, and attributable burden of disease for 88 risk factors in 204 countries and territories and 811 subnational locations, from 1990 to 2021.
- Published
- 2024
- Full Text
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18. Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021
- Author
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Vollset, Stein Emil, Ababneh, Hazim S, Abate, Yohannes Habtegiorgis, Abbafati, Cristiana, Abbasgholizadeh, Rouzbeh, Abbasian, Mohammadreza, Abbastabar, Hedayat, Abd Al Magied, Abdallah H A, Abd ElHafeez, Samar, Abdelkader, Atef, Abdelmasseh, Michael, Abd-Elsalam, Sherief, Abdi, Parsa, Abdollahi, Mohammad, Abdoun, Meriem, Abdullahi, Auwal, Abebe, Mesfin, Abiodun, Olumide, Aboagye, Richard Gyan, Abolhassani, Hassan, Abouzid, Mohamed, Aboye, Girma Beressa, Abreu, Lucas Guimarães, Absalan, Abdorrahim, Abualruz, Hasan, Abubakar, Bilyaminu, Abukhadijah, Hana Jihad Jihad, Addolorato, Giovanni, Adekanmbi, Victor, Adetunji, Charles Oluwaseun, Adetunji, Juliana Bunmi, Adeyeoluwa, Temitayo Esther, Adha, Rishan, Adhikary, Ripon Kumar, Adnani, Qorinah Estiningtyas Sakilah, Adzigbli, Leticia Akua, Afrashteh, Fatemeh, Afzal, Muhammad Sohail, Afzal, Saira, Agbozo, Faith, Agodi, Antonella, Agrawal, Anurag, Agyemang-Duah, Williams, Ahinkorah, Bright Opoku, Ahlstrom, Austin J, Ahmad, Aqeel, Ahmad, Firdos, Ahmad, Muayyad M, Ahmad, Sajjad, Ahmad, Shahzaib, Ahmed, Anisuddin, Ahmed, Ayman, Ahmed, Haroon, Ahmed, Safoora, Ahmed, Syed Anees, Akinosoglou, Karolina, Akkaif, Mohammed Ahmed, Akrami, Ashley E, Akter, Ema, Al Awaidy, Salah, Al Hasan, Syed Mahfuz, Al Mosa, Amjad S, Al Ta'ani, Omar, Al Zaabi, Omar Ali Mohammed, Alahdab, Fares, Alajlani, Muaaz M, Al-Ajlouni, Yazan, Alalalmeh, Samer O, Al-Aly, Ziyad, Alam, Khurshid, Alam, Noore, Alam, Tahiya, Alam, Zufishan, Al-amer, Rasmieh Mustafa, Alanezi, Fahad Mashhour, Alanzi, Turki M, Albakri, Almaza, Aldhaleei, Wafa A, Aldridge, Robert W, Alemohammad, Seyedeh Yasaman, Alemu, Yihun Mulugeta, Al-Gheethi, Adel Ali Saeed, Al-Hanawi, Mohammed Khaled, Ali, Abid, Ali, Amjad, Ali, Iman, Ali, Mohammed Usman, Ali, Rafat, Ali, Syed Shujait Shujait, Ali, Victor Ekoche, Ali, Waad, Al-Ibraheem, Akram, Alicandro, Gianfranco, Alif, Sheikh Mohammad, Aljunid, Syed Mohamed, Alla, François, Almazan, Joseph Uy, Al-Mekhlafi, Hesham M, Alqutaibi, Ahmed Yaseen, 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- Abstract
Future trends in disease burden and drivers of health are of great interest to policy makers and the public at large. This information can be used for policy and long-term health investment, planning, and prioritisation. We have expanded and improved upon previous forecasts produced as part of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) and provide a reference forecast (the most likely future), and alternative scenarios assessing disease burden trajectories if selected sets of risk factors were eliminated from current levels by 2050.
- Published
- 2024
- Full Text
- View/download PDF
19. Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021
- Author
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Sergeevich, Zhang, Haijun, Zhang, Meixin, Zhang, Yunquan, Zhong, Chenwen, Zhou, Juexiao, Zhu, Bin, Zhu, Lei, Zielińska, Magdalena, Zou, Zhiyong, Zyoud, Samer H, Murray, Christopher J L, Smith, Amanda E, and Vollset, Stein Emil
- Abstract
Accurate assessments of current and future fertility—including overall trends and changing population age structures across countries and regions—are essential to help plan for the profound social, economic, environmental, and geopolitical challenges that these changes will bring. Estimates and projections of fertility are necessary to inform policies involving resource and health-care needs, labour supply, education, gender equality, and family planning and support. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 produced up-to-date and comprehensive demographic assessments of key fertility indicators at global, regional, and national levels from 1950 to 2021 and forecast fertility metrics to 2100 based on a reference scenario and key policy-dependent alternative scenarios.
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- 2024
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20. Labidostomma motasirediscovered: a witness of the Messinian crisis?(Acari: Labidostommatidae)
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Bertrand, Michel, Manu, Minodora, Sarbu, Serban M., and Stefan, Andrei
- Abstract
SummaryLabidostomma motasiIavorschi, 1992 was discovered and described from a single female in the newly discovered hypoxic sulfidic, ancient and isolated Movile Cave (Romania). Male and female specimens collected recently brought new data for the description of this species. The morphology shows affinities and close relation with the species allied to L. integrumBerlese, 1911 which is distributed all around the Mediterranean Basin and Asia. As representatives of the family are also known from Baltic Amber (more than 40 My), this blind species in Movile Cave first attests of a probable adaptation of an epigean species to the cave environment: a model of two congeneric and sympatric species, one living in a cave and the second (L. integrum) living in soils in a region where the labidostommatid fauna is well referenced. This species may have migrated in caves, a winning option which allowed it to survive during past climatic variation since Miocene. Genetic data obtained from three specimens of this species were compared with the data published in Genbank showing a clear distinction between the subgenera LabidostommaKramer, 1879 and NicoletiellaCanestrini, 1882. Overall, this species completes the long list of endemic invertebrates found in the sulfidic groundwater ecosystem of Movile Cave. Knowledge of the history of this cave system allowed us to estimate the isolation of this species in the Movile labyrinth during the ancient geological episodes following the Messinian Crisis.
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- 2024
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21. Annealing Effects on the Charging–Discharging Mechanism in Trilayer Al2O3/Ge/Al2O3 Memory Structures.
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Stavarache, Ionel, Palade, Catalin, Maraloiu, Valentin Adrian, Teodorescu, Valentin Serban, Stoica, Toma, and Ciurea, Magdalena Lidia
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- 2024
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22. Acute mitral isthmus block during catheter ablation with vein of Marshall ethanol infusion: Angiographic considerations.
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Andronache, Marius, Pastorcici, Anda, Amet, Denis, Blendea, Dan, Boudias, Antoine, Mazieres, Guillaume, Rosu, Radu, Cismaru, Gabriel, Puiu, Mihai, Mot, Stefan, Serban, Adela, Mottref, Pascal, Dauphin, Claire, Moini, Cyrus, Lellouche, Nicolas, and Massoulié, Grégoire
- Abstract
[Display omitted] • 149 consecutive patients with long-standing AF or peri-mitral flutter ablation. • EIVOM was feasible in 82% of cases. • Systematic EIVOM achieved complete MIB in 94% of feasible cases. • Systematic EIVOM achieved complete MIB in 77% of the total population. • No major complications during the procedure or postprocedural monitoring. • Failure to obtain MIB linked with increased MI length and high left atrial volume. Achieving bidirectional mitral isthmus block is still challenging. Conventional ablation methods involve radiofrequency applications on the endocardial aspect of the lateral mitral isthmus, and often epicardial applications inside the coronary sinus. To evaluate the impact of the systematic use of ethanol infusion in the vein of Marshall on the achievement of acute mitral isthmus block of additional epicardial component lesion. We evaluated patients referred to two centres for long-standing persistent atrial fibrillation ablation or recurrent peri-mitral flutter. All patients had pulmonary vein isolation and mitral isthmus line using ethanol infusion in the vein of Marshall for the first procedure and additional radiofrequency ablation lesion if necessary. For redo procedures, additional ablations (atrial lines and complex fractionated atrial electrogram ablations, if needed) were also performed. We included 149 patients, and ethanol infusion in the vein of Marshall was not performed in 27 patients (18%). Among 122 patients, 115 had long-standing persistent atrial fibrillation (94.2%) and seven had peri-mitral flutter (5.8%). The mean duration of continuous atrial fibrillation was 53 months before ablation. Acute bidirectional mitral isthmus block was obtained in 115 (94.2%) of the 122 patients who received ethanol infusion in the vein of Marshall (77% when considering the total population). The mean radiofrequency delivery time to obtain mitral isthmus block was 2.6 minutes for the endocardial mitral isthmus radiofrequency ablation and 2.6 minutes for the epicardial mitral isthmus radiofrequency ablation. Failure to obtain mitral isthmus block was associated with increased mitral isthmus length and left atrial dilation. No major complications related to ethanol infusion in the vein of Marshall were observed. Ethanol infusion in the vein of Marshall, when feasible (82%), was a safe approach to obtaining a high success rate (94%) of acute bidirectional endocardial and epicardial mitral isthmus block. [ABSTRACT FROM AUTHOR]
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- 2024
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23. LGYSB:NdHigh-Performance Lasing in the Near-Infrared Region.
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Broasca, Alin, Greculeasa, Madalin, Voicu, Flavius, Hau, Stefania, Gheorghe, Cristina, Croitoru, Gabriela, Pavel, Nicolaie, Stanciu, George, Petris, Adrian, Gheorghe, Petronela, Albota, Florin, Serban, Andreea, and Gheorghe, Lucian
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- 2024
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24. An Empirical Investigation into the Utility of Descriptions of Inclusive Vocational Excellence Practices.
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MIRONOV, Cosmina, CIOLAN, Lucian, ILIESCU, Dragos, NEDELCU, Anca, ZANFIRESCU, Șerban, SERBAN, Madlen, and AVARVARE, Daniela
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VOCATIONAL education ,STATISTICS ,EXCELLENCE ,RESPECT - Abstract
The present paper investigated how inclusive vocational excellence (IVE) practices specific to vocational education and training (VET) can be described in an effective and transparent manner. A framework for the description of such practices was proposed, and then 44 descriptions of practices were collected with this framework from an international sample of providers of such practices from four countries. Expert raters have rated the quality of these descriptions, in terms of how much they respect the proposed structure, provide relevant information about the proposed practice, provide relevant information about the manner in which the practice was implemented and offers a clear and explicit description, further usable by other interested VET institutions. Statistical analyses have then revealed that the framework generates more consistent descriptions for some domains then for others. Implications for practice are discussed. [ABSTRACT FROM AUTHOR]
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- 2024
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25. Intensive Care Fundamentals in Romania. A Critical Step in Romanian Intensive Care Education
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Balan, Cosmin, Bubenek-Turconi, Serban-Ion, and Al-Haddad, Mo
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- 2024
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26. Colorimetric Properties of Bombyx moriSilk Fibroin
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Sandau, Kolton C., Arrigali, Elizabeth M., Serban, Bogdan A., and Serban, Monica A.
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Recent reports highlighted several novel applications for the Bombyx morisilk fibroin (SF), as edible coatings for the preservation of food freshness, smart labels, or packaging materials. This study complements these reports and additionally describes the colorimetric sensing properties of the natural protein that could be explored to enhance the practical value of such applications. Our data show that in response to pH changes, reconstituted SF is able to undergo visible color changes that correlate with the intensity of the stimuli, regardless of its physical format or physical cross-linking state. The intensity of the developed color was proportional to the extent of the protein’s hydrolytic degradation. We also found that these pH-driven color changes were reversible and interchangeable, with colorless samples at neutral pH, purple in acidic environments, and yellow under basic conditions. Our mechanistic studies identified tryptophan as being responsible for these colorimetric responses, which could be further intensified by the presence of ionized tyrosine functionalities. In addition, we determined that SF’s sensing properties also applied to ultraviolet light exposure. Finally, we showed that the innate sensing capabilities of activated SF can be enhanced via the covalent incorporation of additional tryptophan into the protein. Overall, our results further support the utility of SF for sensing applications.
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- 2023
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27. LGYSB:Nd─High-Performance Lasing in the Near-Infrared Region
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Broasca, Alin, Greculeasa, Madalin, Voicu, Flavius, Hau, Stefania, Gheorghe, Cristina, Croitoru, Gabriela, Pavel, Nicolaie, Stanciu, George, Petris, Adrian, Gheorghe, Petronela, Albota, Florin, Serban, Andreea, and Gheorghe, Lucian
- Abstract
Three incongruent melting LawNdxGdyYzSc4–w–x–y–z(BO3)4(LGYSB:Nd) crystals with different Yconcentrations (z= 0.15, 0.05, and 0.025) have been grown by the Czochralski method for the first time. The LGYSB:Nd-type crystals exhibit an acentric structure similar to that of the natural mineral huntite CaMg3(CO3)4, with space group R32. The composition of the LGYSB:Nd_3 (z= 0.025) crystal grown from the starting melt composition La0.628Gd0.547Y0.025Nd0.05Sc2.75(BO3)4was measured by inductively coupled plasma mass spectrometry method, and it was found to be La0.6794Gd0.4105Y0.0178Nd0.0381Sc2.8542(BO3)4. The transversal spatial distribution of the refractive index in the LGYSB:Nd_3 crystal was investigated. Third-order nonlinear optical susceptibility χ(3)of the LGYSB:Nd_3 crystal was determined from third-harmonic generation experiments with ultrashort (fs) laser pulses. The optical transmission spectrum was measured in the range of 200–2000 nm. The absorption cross-section at 808 nm in σ-polarization was determined to be 1.18 × 10–19cm2for the LGYSB:Nd_3 crystal. The 10K absorption spectra revealed that the Nd3+ions occupy only La3+cationic sites in the LGYSB host matrix. The emission cross-section at 1064 nm in σ-polarization was determined to be σem(σ) = 1.74 × 10–19cm2for the LGYSB:Nd_3 crystal. The fluorescence lifetime was found to be τ = 115 μs for all of the LGYSB:Nd crystals. The LGYSB:Nd_3 laser was operated at an emission wavelength of 1062 nm with very high slope efficiencies of ηsa= 0.74 and ηsa= 0.64 in quasi-cw and cw regimes, respectively.
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- 2024
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28. Determinants of outcome of transsphenoidal surgery for Cushing disease in a single-centre series
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Serban, A. L., Del Sindaco, G., Sala, E., Carosi, G., Indirli, R., Rodari, G., Giavoli, C., Locatelli, M., Carrabba, G., Bertani, G., Marfia, G., Mantovani, G., Arosio, M., and Ferrante, E.
- Abstract
Background: First-line therapy of Cushing disease (CD) is transsphenoidal surgery (TSS) aimed to obtain a complete removal of the pituitary adenoma and remission of disease. Purpose: To analyse the surgical outcome of patients with CD who underwent TSS in our Centre. Methods: Retrospective analysis on patients with CD who underwent TSS between 1990 and 2016. Results: We analysed 102 TSS that included: 84 first TSS and 18 second and third TSS. The overall remission rate after surgery was 76.5%, with a significant higher percentage of remitted patients after the first TSS compared to the subsequent TSS (82% vs 50%, p= 0.014). The remission after the first TSS was significantly higher when performed by a dedicated surgical team (DST) (89.8% vs 71% p= 0.04) and when the immunohistochemical examination confirmed the adrenocorticotropic adenoma (87% vs 55%, p= 0.04). Neuroradiological findings influenced the surgical outcome in a non-significant manner. Post-TSS complications were reported in 32 patients, with no significant variation when TSS was performed by DST. In case of reintervention, remission of disease was obtained in 72.7% of microadenoma, while no remitted patients were observed in case of macroadenomas. The DST did not significantly improve the outcome. Conclusion: Cushing disease is characterized by a broad spectrum of neuroradiological presentation. Despite the availability of a DST make the TSS a safe and effective first-line treatment among all these patients, a precise pre-treatment evaluation is needed in order to define the aim of neurosurgery and to schedule the management of recurrent disease.
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- 2024
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29. COVID-19 case management in primary dental care settings in Yorkshire and the Humber
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Granger, Clare, Twigg, Joshua A., Whiston, Sandra, Grant, Siobhan M. B., and Serban, Stefan
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IntroductionEmerging guidance during the COVID-19 pandemic aimed to minimise transmission risk within dental settings. This service evaluation provides an overview of reported cases of COVID-19 among primary dental care staff within Yorkshire and the Humber.
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- 2024
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30. Ventricular hypertrophy in a young weightlifter
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Dadarlat-Pop, Alexandra, Tomoaia, Raluca, and Serban, Adela Mihaela
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- 2024
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31. Improving the fit of filtering facepiece respirators
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Shah, Kamini, Serban, Stefan, and Douglas, Gail V. A.
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AimsTo assess the effectiveness and acceptability of smartphone customised frame technology to improve the fit of disposable filtering facepiece class 3 (FFP3) respirators for dental staff who previously failed fit testing.
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- 2024
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32. The Next Generationfor Manufacturing Competitiveness?: Investigating the Influence of Industry-Driven Outreach on Children Career Perceptions
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Strimel, Greg J., Krause, Liesl, Bosman, Lisa, Serban, Sydney, and Harrell, Sascha
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Manufacturing is considered one of the major economic drivers in the United States. However, a challenge for manufacturing competitiveness can be the negative perception of the industry held by children, and society as a whole, which may make them reluctant to pursue manufacturing careers and fulfill the projected workforce demands. Accordingly, there have been a number of talent pipeline initiatives to address the issues related to (1) the availability of a skilled workforce, (2) the preparation of students for the jobs of tomorrow, and (3) teacher access to the tools necessary to inspire children to pursue high-demand career pathways. While these industry-driven outreach initiatives are often developed with the best intentions, research attempts focused on better understanding the influences of these initiatives on children’s perceptions of manufacturing-related careers are necessary. Therefore, this study focused on investigating the career perceptions of children (Grades K-8) and the influence of an industry-led summer camp focused on robotics in manufacturing. To do so, data were collected from career-perception surveys and a “Draw-A-Manufacturer” test, which were administered before and after the camp experience. The influences of the summer camp on the participants’ career perceptions and interests are presented and used as a foundation for discussions and recommendations for developing outreach initiatives and preparing children for the future of work.
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- 2024
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33. Strategic and tactical management of warehousing in distribution logistics
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Raicu, Serban, Costescu, Dorinela, Popa, Mihaela, and Bujor, Cosmin-Robert
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The temporal, structural and spatial variations of demand in urban distribution logistics systems leads to specific requirements on management at all levels. Especially strategic management, which involves long-term decisions and significant investments, is marked by multiple uncertainties. The analysis of an operator's own warehouse in a urban logistic system demonstrates the difficulty of deciding the storage capacity as an initial phase of warehouse design. Uncertainties cannot be eliminated in warehouse design even if other causes of the storage demand variations are excluded and only seasonal variations, for which information is available, are considered. Temporary excesses and/or shortages of storage capacity are inevitable. In this regard, this paper demonstrates how tactical management decisions can provide solutions with minimum consumption of resources in various operating circumstances that are impossible to consider in strategic decisions and cause storage capacity deficit.
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- 2024
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34. A GPU-accelerated simulator for the DEM analysis of granular systems composed of clump-shaped elements
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Zhang, Ruochun, Vanden Heuvel, Colin, Schepelmann, Alexander, Rogg, Arno, Apostolopoulos, Dimitrios, Chandler, Samuel, Serban, Radu, and Negrut, Dan
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This paper discusses the use of the discrete element method (DEM) to simulate the dynamics of granular systems made up of elements with nontrivial geometries. The DEM simulator is GPU accelerated and can handle elements whose shape is defined as the union with overlap of diverse sets of spheres with user-specified radii. The simulator can also handle complex materials since each sphere in an element can have its own Young’s modulus E, Poisson ratio ν, friction coefficient μ, and coefficient of restitution CoR. To demonstrate the simulator, this paper introduces a “digital simulant” (DS), a replica of the GRC-1 lunar simulant. The DS follows an element size distribution similar but not identical to that of GRC-1. The predictive attributes of the simulator are validated via several numerical experiments: repose angle, cone penetration, drawbar pull, and rover incline-climbing tests. Subsequently, a sensitivity analysis is carried out to gauge how the slope vs. slip curves change when the element shape, element size, and friction coefficient change. The paper concludes with a VIPER rover simulation that confirms a recently proposed granular scaling law. The simulation involves more than 11 million elements composed of more than 34 million spheres of different radii. The simulator works in the Chrono framework and can utilize two GPUs concurrently. The GPU code for the simulator and all numerical experiments discussed are open-source and available on GitHub for reproducibility studies and unfettered use and distribution. The DEM simulator introduced here: can handle complex particle geometry; can capture material breakage; can handle user-defined contact forces; allows for one DEM element to have different material properties in different regions of the element; is fast and runs on commodity hardware; can leverage two GPU cards simultaneously; it has a Python interface; and, it works in co-simulation mode with and augments Chrono, an established multi-body dynamics platform that supports the physics-based simulation of complex mechanical systems.
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- 2024
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35. Anion Exchange Ionomers Enable Sustained Pure-Water Electrolysis Using Platinum-Group-Metal-Free Electrocatalysts.
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Zheng, Yiwei, Serban, Ariana, Zhang, Haoyue, Chen, Nanjun, Song, Fang, and Hu, Xile
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- 2023
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36. Clinical Features and Natural History of Paediatric Patients with Ulcerative Proctitis: A Multicentre Study from the Paediatric IBD Porto Group of ESPGHAN.
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Tal, Noa, Tzivinikos, Christos, Gasparetto, Marco, Serban, Daniela E, Zifman, Eyal, Hojsak, Iva, Ledder, Oren, Feler, Anat Yerushalmy, Rolandsdotter, Helena, Aloi, Marina, Bramuzzo, Matteo, Buderus, Stephan, Lionetti, Paolo, Norsa, Lorenzo, Norden, Christoph, Urlep, Darja, Romano, Claudio, Shaoul, Ron, Martinez-Vinson, Christine, and Karoliny, Anna
- Abstract
Background and Aims Ulcerative proctitis [UP] is an uncommon presentation in paediatric patients with ulcerative colitis. We aimed to characterize the clinical features and natural history of UP in children, and to identify predictors of poor outcomes. Methods This was a retrospective study involving 37 sites affiliated with the IBD Porto Group of ESPGHAN. Data were collected from patients aged <18 years diagnosed with UP between January 1, 2016 and December 31, 2020. Results We identified 196 patients with UP (median age at diagnosis 14.6 years [interquartile range, IQR 12.5–16.0]), with a median follow-up of 2.7 years [IQR 1.7–3.8]. The most common presenting symptoms were bloody stools [95%], abdominal pain [61%] and diarrhoea [47%]. At diagnosis, the median paediatric ulcerative colitis activity index [PUCAI] score was 25 [IQR 20–35], but most patients exhibited moderate–severe endoscopic inflammation. By the end of induction, 5-aminosalicylic acid administration orally, topically or both resulted in clinical remission rates of 48%, 48%, and 73%, respectively. The rates of treatment escalation to biologics at 1, 3, and 5 years were 10%, 22%, and 43%, respectively. In multivariate analysis, the PUCAI score at diagnosis was significantly associated with initiation of systemic steroids, or biologics, and subsequent acute severe colitis events and inflammatory bowel disease-associated admission, with a score ≥35 providing an increased risk for poor outcomes. By the end of follow-up, 3.1% of patients underwent colectomy. Patients with UP that experienced proximal disease progression during follow-up [48%] had significantly higher rates of a caecal patch at diagnosis and higher PUCAI score by the end of induction, compared to those without progression. Conclusion Paediatric patients with UP exhibit high rates of treatment escalation and proximal disease extension. [ABSTRACT FROM AUTHOR]
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- 2023
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37. Prevention is better than cure: identifying and dealing with the key features involved in the prevention of gestational diabetes - A bird's eye view.
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CHELU, S., KUNDNANI, N. R., CHIRIAC, V., NEAGU, M. N., SERBAN, D., IANCU, M. A., NISTOR, D., and BORZA, C.
- Abstract
Gestational diabetes (GDM) is considered to be the most common metabolic problem of pregnancy, which, if not recognized and treated on time, can lead to devastating effects on both the mother's health and the health of the fetus and the newborns. Many studies have revealed that the children born of GDM mothers or grandmothers have higher chances of developing diabetes type I or type II later in their life. Early identification of risk factors can help prevent the appearance of severe GDM and its complications witnessed both in the child and the mother. Obesity is one of the major risk factors that should not be ignored, and obese females should first undergo weight reduction plans in case of planned pregnancies. Other risk factors include a family history of DM arterial hypertension, significant weight gain during pregnancy, short sleep duration, women's exposure to stressful environments, changes in alpha and beta microbiota, and air pollution. Proper care should be provided to females of reproductive age both before and during pregnancy to avoid complications. Awareness programs for healthy lifestyles and diets, oral hygiene maintenance guides, and regular health check-ups can all be considered as a key to a healthy society. Expanding the analysis of gut microbiota in individuals at a heightened risk of GDM can hold particular value, especially during the preconception phase. The alterations in gut microbiota can serve as crucial factors in enhancing lifestyle modifications prior to conception. Further studies are required in this direction to decrease the prevalence of GDM, and efficient measures should be implemented before the consequences appear. [ABSTRACT FROM AUTHOR]
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- 2023
38. Impact on the Volume of Pathology Reports Before and During the COVID-19 Pandemic in SEER Cancer Registries.
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Chtourou, Amina, Sanchez, Pamela V., Golden, Todd, Huann-Sheng Chen, Schwartz, Stephen M., Xiao-Cheng Wu, Hernandez, Brenda Y., Harrison, Jovanka N., Penberthy, Lynne, and Negoita, Serban
- Abstract
Introduction: Health care procedures including cancer screening and diagnosis were interrupted due to the COVID-19 pandemic. The extent of this impact on cancer care in the United States is not fully understood. We investigated pathology report volume as a reflection of trends in oncology services pre-pandemic and during the pandemic. Methods: Electronic pathology reports were obtained from 11 U.S. central cancer registries from NCI's SEER Program. The reports were sorted by cancer site and document type using a validated algorithm. Joinpoint regression was used to model temporal trends from January 2018 to February 2020, project expected counts from March 2020 to February 2021 and calculate observed-to-expected ratios. Results were stratified by sex, age, cancer site, and report type. Results: During the first 3 months of the pandemic, pathology report volume decreased by 25.5% and 17.4% for biopsy and surgery reports, respectively. The 12-month O/E ratio (March 2020-February 2021) was lowest for women (O/E 0.90) and patients 65 years and older (O/E 0.91) and lower for cancers with screening (melanoma skin, O/E 0.86; breast, O/E 0.88; lung O/E 0.89, prostate, O/E 0.90; colorectal, O/E 0.91) when compared with all other cancers combined. Conclusions: These findings indicate a decrease in cancer diagnosis, likely due to the COVID-19 pandemic. This decrease in the number of pathology reports may result in a stage shift causing a subsequent longer-term impact on survival patterns. Impact: Investigation on the longer-term impact of the pandemic on pathology services is vital to understand if cancer care delivery levels continue to be affected. [ABSTRACT FROM AUTHOR]
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- 2023
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39. CONSIDERATION ABOUT SINTERED DEFORMED MATERIALS THROUGH MECHANICAL TESTING IN CRYOGENIC.
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Ionici, Cristina and Serban, Crinela
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DEFORMATIONS (Mechanics) ,LOW temperatures ,POROSITY ,CONFORMANCE testing - Abstract
In presents analyzes show that an intensification of the material densification in the case of low temperatures that leads to an increased resistance in the case of mechanic requests, large deformation tensions being accepted. For the materials sintered by the chosen composition for the type of test pieces submitted to the trial at environmental temperature, the corresponding breakage the obtained porosity may be a ductile breakage. [ABSTRACT FROM AUTHOR]
- Published
- 2023
40. Minimally invasive approach for synchronous resection of small bowel endocrine tumour with bilobar LIVER metastases (WITH VIDEO).
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Suciu, Serban, Del Basso, Céleste, and Tranchart, Hadrien
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SMALL intestine ,TUMORS ,MINIMALLY invasive procedures - Published
- 2024
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41. Best practice models for dental care delivery for people experiencing homelessness
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Serban, Stefan, Bradley, Natalie, Atkins, Ben, Whiston, Sandra, and Witton, Robert
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People experiencing homelessness have been encountering significant barriers in accessing healthcare services, including dental care services. There are several definitions for homelessness: it includes people sleeping rough but also people living in temporary accommodation. These categories are dynamic and individuals often find themselves on a continuum oscillating between sleeping rough and living in temporary accommodation. Their health-seeking behaviours are shaped by their living arrangements; therefore, one single model of dental care service delivery might not capture the needs of all those experiencing homelessness within an area. The service models presented in this paper are based on primary care delivery, mobile dental units and community clinics. Each of these models presents advantages and disadvantages and consideration should be given to delivering these on a complementary basis to maximise access to dental care, regardless of where patients are on the continuum between sleeping rough and living in temporary accommodation.
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- 2023
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42. Distributed Control of Descriptor Networks: A Convex Procedure for Augmented Sparsity
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Sperila, Andrei, Oara, Cristian, Ciubotaru, Bogdan D., and Sabau, Serban
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For networks of systems, with possibly improper transfer function matrices, we present a design framework that enables
control, while imposing sparsity constraints on the coprime factors of the controller. We propose a convex and iterative optimization procedure with guaranteed convergence to obtain distributed controllers. By exploiting the robustness-oriented nature of our proposed approach, we provide the means to obtain sparse representations of our control laws that may not be directly supported by the nominal model of the network.$\mathcal {H}_\infty$ - Published
- 2023
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43. Network Realization Functions for Optimal Distributed Control
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Sabau, Serban, Sperila, Andrei, Oara, Cristian, and Jadbabaie, Ali
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In this article, we discuss a distributed control architecture, aimed at networks with linear and time-invariant dynamics, which is amenable to convex formulations for controller design. The proposed approach is well suited for large-scale systems, since the resulting feedback schemes completely avoid the exchange of internal states, i.e., plant or controller states, among subcontrollers. In addition, we provide state-space formulas for these subcontrollers, able to be implemented in a distributed manner.
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- 2023
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44. Implementation of digital health technology in clinical trials: the 6R framework
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Durán, Cristina Ortega, Bonam, Matthew, Björk, Elisabeth, Hughes, Rod, Ghiorghiu, Serban, Massacesi, Cristian, Campbell, Alicyn, Hutchison, Emmette, Pangalos, Menelas N., and Galbraith, Susan
- Abstract
AstraZeneca has introduced digital health solutions into clinical trials, demonstrating improved patient experience, accelerated timelines and reduced costs.
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- 2023
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45. The Global, Regional, and National Burden of Adult Lip, Oral, and Pharyngeal Cancer in 204 Countries and Territories: A Systematic Analysis for the Global Burden of Disease Study 2019
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Cunha, Amanda Ramos da, Compton, Kelly, Xu, Rixing, Mishra, Rashmi, Drangsholt, Mark Thomas, Antunes, Jose Leopoldo Ferreira, Kerr, Alexander R., Acheson, Alistair R., Lu, Dan, Wallace, Lindsey E., Kocarnik, Jonathan M., Fu, Weijia, Dean, Frances E., Pennini, Alyssa, Henrikson, Hannah Jacqueline, Alam, Tahiya, Ababneh, Emad, Abd-Elsalam, Sherief, Abdoun, Meriem, Abidi, Hassan, Abubaker Ali, Hiwa, Abu-Gharbieh, Eman, Adane, Tigist Demssew, Addo, Isaac Yeboah, Ahmad, Aqeel, Ahmad, Sajjad, Ahmed Rashid, Tarik, Akonde, Maxwell, Al Hamad, Hanadi, Alahdab, Fares, Alimohamadi, Yousef, Alipour, Vahid, Al-Maweri, Sadeq Ali, Alsharif, Ubai, Ansari-Moghaddam, Alireza, Anwar, Sumadi Lukman, Anyasodor, Anayochukwu Edward, Arabloo, Jalal, Aravkin, Aleksandr Y., Aruleba, Raphael Taiwo, Asaad, Malke, Ashraf, Tahira, Athari, Seyyed Shamsadin, Attia, Sameh, Azadnajafabad, Sina, Azangou-Khyavy, Mohammadreza, Badar, Muhammad, Baghcheghi, Nayereh, Banach, Maciej, Bardhan, Mainak, Barqawi, Hiba Jawdat, Bashir, Nasir Z., Bashiri, Azadeh, Benzian, Habib, Bernabe, Eduardo, Bhagat, Devidas S., Bhojaraja, Vijayalakshmi S., Bjørge, Tone, Bouaoud, Souad, Braithwaite, Dejana, Briko, Nikolay Ivanovich, Calina, Daniela, Carreras, Giulia, Chakraborty, Promit Ananyo, Chattu, Vijay Kumar, Chaurasia, Akhilanand, Chen, Meng Xuan, Cho, William C. S., Chu, Dinh-Toi, Chukwu, Isaac Sunday, Chung, Eunice, Cruz-Martins, Natália, Dadras, Omid, Dai, Xiaochen, Dandona, Lalit, Dandona, Rakhi, Daneshpajouhnejad, Parnaz, Darvishi Cheshmeh Soltani, Reza, Darwesh, Aso Mohammad, Debela, Sisay Abebe, Derbew Molla, Meseret, Dessalegn, Fikadu Nugusu, Dianati-Nasab, Mostafa, Digesa, Lankamo Ena, Dixit, Shilpi Gupta, Dixit, Abhinav, Djalalinia, Shirin, El Sayed, Iman, El Tantawi, Maha, Enyew, Daniel Berhanie, Erku, Daniel Asfaw, Ezzeddini, Rana, Fagbamigbe, Adeniyi Francis, Falzone, Luca, Fetensa, Getahun, Fukumoto, Takeshi, Gaewkhiew, Piyada, Gallus, Silvano, Gebrehiwot, Mesfin, Ghashghaee, Ahmad, Gill, Paramjit Singh, Golechha, Mahaveer, Goleij, Pouya, Gomez, Ricardo Santiago, Gorini, Giuseppe, Guimaraes, Andre Luiz Sena, Gupta, Bhawna, Gupta, Sapna, Gupta, Veer Bala, Gupta, Vivek Kumar, Haj-Mirzaian, Arvin, Halboub, Esam S., Halwani, Rabih, Hanif, Asif, Hariyani, Ninuk, Harorani, Mehdi, Hasani, Hamidreza, Hassan, Abbas M., Hassanipour, Soheil, Hassen, Mohammed Bheser, Hay, Simon I., Hayat, Khezar, Herrera-Serna, Brenda Yuliana, Holla, Ramesh, Horita, Nobuyuki, Hosseinzadeh, Mehdi, Hussain, Salman, Ilesanmi, Olayinka Stephen, Ilic, Irena M., Ilic, Milena D., Isola, Gaetano, Jaiswal, Abhishek, Jani, Chinmay T., Javaheri, Tahereh, Jayarajah, Umesh, Jayaram, Shubha, Joseph, Nitin, Kadashetti, Vidya, Kandaswamy, Eswar, Karanth, Shama D., Karaye, Ibraheem M., Kauppila, Joonas H., Kaur, Harkiran, Keykhaei, Mohammad, Khader, Yousef Saleh, Khajuria, Himanshu, Khanali, Javad, Khatib, Mahalaqua Nazli, Khayat Kashani, Hamid Reza, Khazeei Tabari, Mohammad Amin, Kim, Min Seo, Kompani, Farzad, Koohestani, Hamid Reza, Kumar, G. Anil, Kurmi, Om P., La Vecchia, Carlo, Lal, Dharmesh Kumar, Landires, Iván, Lasrado, Savita, Ledda, Caterina, Lee, Yo Han, Libra, Massimo, Lim, Stephen S., Listl, Stefan, Lopukhov, Platon D., Mafi, Ahmad R., Mahumud, Rashidul Alam, Malik, Ahmad Azam, Mathur, Manu Raj, Maulud, Sazan Qadir, Meena, Jitendra Kumar, Mehrabi Nasab, Entezar, Mestrovic, Tomislav, Mirfakhraie, Reza, Misganaw, Awoke, Misra, Sanjeev, Mithra, Prasanna, Mohammad, Yousef, Mohammadi, Mokhtar, Mohammadi, Esmaeil, Mokdad, Ali H., Moni, Mohammad Ali, Moraga, Paula, Morrison, Shane Douglas, Mozaffari, Hamid Reza, Mubarik, Sumaira, Murray, Christopher J. L., Nair, Tapas Sadasivan, Narasimha Swamy, Sreenivas, Narayana, Aparna Ichalangod, Nassereldine, Hasan, Natto, Zuhair S., Nayak, Biswa Prakash, Negru, Serban Mircea, Nggada, Haruna Asura, Nouraei, Hasti, Nuñez-Samudio, Virginia, Oancea, Bogdan, Olagunju, Andrew T., Omar Bali, Ahmed, Padron-Monedero, Alicia, Padubidri, Jagadish Rao, Pandey, Anamika, Pardhan, Shahina, Patel, Jay, Pezzani, Raffaele, Piracha, Zahra Zahid, Rabiee, Navid, Radhakrishnan, Venkatraman, Radhakrishnan, Raghu Anekal, Rahmani, Amir Masoud, Rahmanian, Vahid, Rao, Chythra R., Rao, Sowmya J., Rath, Goura Kishor, Rawaf, David Laith, Rawaf, Salman, Rawassizadeh, Reza, Razeghinia, Mohammad Sadegh, Rezaei, Nazila, Rezaei, Negar, Rezaei, Nima, Rezapour, Aziz, Riad, Abanoub, Roberts, Thomas J., Romero-Rodríguez, Esperanza, Roshandel, Gholamreza, S., Manjula, S. N., Chandan, Saddik, Basema, Saeb, Mohammad Reza, Saeed, Umar, Safaei, Mohsen, Sahebazzamani, Maryam, Sahebkar, Amirhossein, Salek Farrokhi, Amir, Samy, Abdallah M., Santric-Milicevic, Milena M., Sathian, Brijesh, Satpathy, Maheswar, Šekerija, Mario, Senthilkumaran, Subramanian, Seylani, Allen, Shafaat, Omid, Shahsavari, Hamid R., Shamsoddin, Erfan, Sharew, Mequannent Melaku, Sharifi-Rad, Javad, Shetty, Jeevan K., Shivakumar, K. M., Shobeiri, Parnian, Shorofi, Seyed Afshin, Shrestha, Sunil, Siddappa Malleshappa, Sudeep K., Singh, Paramdeep, Singh, Jasvinder A., Singh, Garima, Sinha, Dhirendra Narain, Solomon, Yonatan, Suleman, Muhammad, Suliankatchi Abdulkader, Rizwan, Taheri Abkenar, Yasaman, Talaat, Iman M., Tan, Ker-Kan, Tbakhi, Abdelghani, Thiyagarajan, Arulmani, Tiyuri, Amir, Tovani-Palone, Marcos Roberto, Unnikrishnan, Bhaskaran, Vo, Bay, Volovat, Simona Ruxandra, Wang, Cong, Westerman, Ronny, Wickramasinghe, Nuwan Darshana, Xiao, Hong, Yu, Chuanhua, Yuce, Deniz, Yunusa, Ismaeel, Zadnik, Vesna, Zare, Iman, Zhang, Zhi-Jiang, Zoladl, Mohammad, Force, Lisa M., and Hugo, Fernando N.
- Abstract
IMPORTANCE: Lip, oral, and pharyngeal cancers are important contributors to cancer burden worldwide, and a comprehensive evaluation of their burden globally, regionally, and nationally is crucial for effective policy planning. OBJECTIVE: To analyze the total and risk-attributable burden of lip and oral cavity cancer (LOC) and other pharyngeal cancer (OPC) for 204 countries and territories and by Socio-demographic Index (SDI) using 2019 Global Burden of Diseases, Injuries, and Risk Factors (GBD) Study estimates. EVIDENCE REVIEW: The incidence, mortality, and disability-adjusted life years (DALYs) due to LOC and OPC from 1990 to 2019 were estimated using GBD 2019 methods. The GBD 2019 comparative risk assessment framework was used to estimate the proportion of deaths and DALYs for LOC and OPC attributable to smoking, tobacco, and alcohol consumption in 2019. FINDINGS: In 2019, 370 000 (95% uncertainty interval [UI], 338 000-401 000) cases and 199 000 (95% UI, 181 000-217 000) deaths for LOC and 167 000 (95% UI, 153 000-180 000) cases and 114 000 (95% UI, 103 000-126 000) deaths for OPC were estimated to occur globally, contributing 5.5 million (95% UI, 5.0-6.0 million) and 3.2 million (95% UI, 2.9-3.6 million) DALYs, respectively. From 1990 to 2019, low-middle and low SDI regions consistently showed the highest age-standardized mortality rates due to LOC and OPC, while the high SDI strata exhibited age-standardized incidence rates decreasing for LOC and increasing for OPC. Globally in 2019, smoking had the greatest contribution to risk-attributable OPC deaths for both sexes (55.8% [95% UI, 49.2%-62.0%] of all OPC deaths in male individuals and 17.4% [95% UI, 13.8%-21.2%] of all OPC deaths in female individuals). Smoking and alcohol both contributed to substantial LOC deaths globally among male individuals (42.3% [95% UI, 35.2%-48.6%] and 40.2% [95% UI, 33.3%-46.8%] of all risk-attributable cancer deaths, respectively), while chewing tobacco contributed to the greatest attributable LOC deaths among female individuals (27.6% [95% UI, 21.5%-33.8%]), driven by high risk-attributable burden in South and Southeast Asia. CONCLUSIONS AND RELEVANCE: In this systematic analysis, disparities in LOC and OPC burden existed across the SDI spectrum, and a considerable percentage of burden was attributable to tobacco and alcohol use. These estimates can contribute to an understanding of the distribution and disparities in LOC and OPC burden globally and support cancer control planning efforts.
- Published
- 2023
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46. An overview of energy intensity of drinking water production and wastewater treatment
- Author
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Paraschiv, Spiru, Paraschiv, Lizica Simona, and Serban, Alexandru
- Abstract
Drinking water has long been a free resource, but its cost is rising due to increased pollution of both surface and aquifer water sources. Drinking water requires special treatment to be potable and usable by the general public, treatments that consume a certain amount of energy. In addition, the treatment process of wastewater before it is discharged into the environment consumes energy. According to the study, the energy required for wastewater treatment is significantly greater than the energy required for preparing drinking water. Water treatment is a significant source of GHG emissions due to the use of energy and chemicals, and reducing energy consumption would significantly reduce our overall carbon footprint. Furthermore, the UN’s Sustainable Development Goals encourage access to safe drinking water and sanitation while also calling for greater resource efficiency. This research aims to provide an overview of the energy used in water treatment. This study attempts to depict the energy used in water treatment. Electricity consumption for water supply and wastewater treatment is substantial and has a significant environmental impact, particularly in countries where electricity is generated using fossil fuels.
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- 2023
- Full Text
- View/download PDF
47. Validation of a novel score to predict which patients with atrial fibrillation and depressed left ventricular ejection fraction will respond to catheter ablation.
- Author
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Serban, Teodor, du fay du Lavallaz, Jeanne, Barker, David Charles, Sticherling, Christian, Kühne, Michael, and Badertscher, Patrick
- Published
- 2023
- Full Text
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48. Phage-Assisted Continuous Evolution (PACE): A Guide Focused on Evolving Protein–DNA Interactions.
- Author
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Popa, Serban C., Inamoto, Ichiro, Thuronyi, B W., and Shin, Jumi A.
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- 2023
- Full Text
- View/download PDF
49. Development and Application of ETCalc, a Unique Online Tool for Estimation of Daily Evapotranspiration.
- Author
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Danielescu, Serban
- Abstract
Copyright of Atmosphere -- Ocean (Taylor & Francis Ltd) is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2023
- Full Text
- View/download PDF
50. Spatially Addressable Multiplex Biodetection by Calibrated Micro/Nanostructured Surfaces.
- Author
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Dobroiu, Serban, van Delft, Falco C.M.J.M., Sudalaiyadum Perumal, Ayyappasamy, Dash, Shantoshini, Aveyard, Jenny, van Zijl, Jeroen, Snijder, Jaap, van den Heuvel, Eric, van Berkum, Jurgen, Blanchard, Marie Pierre, Favard, Cyril, and Nicolau, Dan V.
- Published
- 2023
- Full Text
- View/download PDF
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