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The Vilsmeier cyclization of 2′-aminochalcones provides a mild one pot synthesis of 2-aryl-4-chloro-N-formyl-1,2-dihydroquinolines. The scope of the reaction has been extended for the synthesis of quinolines themselves, by replacing 2′-aminochalcones with 2′-azidochalcones as the starting material. The yields are reasonably good and a plausible mechanism for the formation of the products in each case has been discussed.

AbstractA facile one pot conversion of alkyl diacylacetates to 2,6-dichloro-3-formyl benzoates using Vilsmeier reagent in a two pronged strategy - conventional heating and microwave irradiation method is reported. The reaction time has been brought down from hours to seconds in microwave irradiation method.

Attempted synthesis of uracil derivatives (2) from acyl ureas (1) resulted in the formation of vinamidinium salts (3) which can be hydrolysed to give dialdehydes. © 1997 Published by Elsevier Science Ltd.

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.