1. Immediate Recurrence of Genetic Focal Segmental Glomerulosclerosis PostKidney Transplant.
- Author
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Subramani, Vignesh, Venkatasubramanian, Vaishnavi, Sethi, Jasmine, Sekar, Aravind, Patil, Shivakumar S. S., Kenwar, Deepesh B., Singh, Sarbpreet, Sharma, Ashish, and Nada, Ritambhra
- Subjects
KIDNEY transplantation ,BIOPSY ,FOCAL segmental glomerulosclerosis ,HOMOGRAFTS ,NEPHRECTOMY ,HEMODIALYSIS ,FLUORESCENT antibody technique ,SURGICAL complications ,PERMEABILITY ,GENETIC variation ,DISEASE relapse ,ANURIA ,GENETIC mutation ,BLOOD transfusion ,GENETICS ,GENETIC testing ,IMMUNOSUPPRESSION - Abstract
Recurrent focal segmental glomerulosclerosis (FSGS) after kidney transplantation is a serious concern with poor allograft outcomes. Possible circulating permeability factors are postulated as pathogenetic factors leading to recurrence. Genetic FSGS is said to have a negligible risk of posttransplant recurrence. Here, we describe an unfortunate patient of genetic FSGS (pathogenic genetic variant) who had a recurrence within hours after transplant and presented with a sudden onset of anuria. The patient did not respond to plasma exchange and subsequently underwent allograft nephrectomy. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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