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Although salvage external-beam radiation therapy (EBRT) is an attractive treatment option for pelvic lymph nodal recurrence (PeNR) in patients with prostate cancer (PCa), limited data are available regarding its long-term efficacy. This study examined the long-term clinical outcomes of patients who underwent salvage pelvic radiation therapy (sPRT) for oligo-recurrent pelvic lymph nodes after definitive EBRT for non-metastatic PCa. Patients who developed PeNR after definitive EBRT and were subsequently treated with sPRT at our institution between November 2007 and December 2015 were retrospectively analyzed. The prescribed dose was 45–50.4 Gy (1.8–2 Gy per fraction) to the upper pelvis, with up to 54–66 Gy (1.8–2 Gy per fraction) for recurrent nodes. Long-term hormonal therapy was used as neoadjuvant and/or adjuvant therapy. The study population consisted of 12 consecutive patients with PeNR after definitive EBRT (median age: 73 years). The median follow-up period was 58.9 months. The 5-year overall survival, PCa-specific survival, biochemical failure-free, clinical failure-free, and castration-resistant PCa-free rates were 82.5, 100.0, 62.3, 81.8, and 81.8%, respectively. No grade 2 or higher sPRT-related late toxicities occurred. In conclusion, more than half of the study patients treated with sPRT had a long-term disease-free status with acceptable morbidities. Moreover, most of the patients maintained hormonal sensitivity. Therefore, this approach may be a promising treatment method for oligo-recurrent pelvic lymph nodes.

The taxonomy of Pseudolachneaand Pseudolachnellais controversial. Some authors have regarded them as congeneric, whereas others have considered them to be distinct genera differentiated merely on the number of conidial septa. A total of 26 isolates of Pseudolachnea-like fungi were subjected to morphological examination and phylogenetic analyses of nuc rDNA internal transcribed spacers 1 and 2 and partial 28S sequences and partial sequence of the translation elongation factor 1α gene. The results indicated that our materials should be classified in four genera: Pseudolachnea, Pseudolachnella, and two new genera, Neopseudolachnellaand Pseudodinemasporium. Although the monophyly of both Pseudolachneaand Pseudolachnellawas confirmed, it was concluded that differences observed in the conidiomatal structure, such as thickness of basal stroma and the excipulum, were more reliable for their circumscription, instead of conidial septation. Neopseudolachnellawas similar to Pseudolachneaand Pseudolachnellain conidial morphology but was characterized by the conidiomata lacking an excipulum, unlike members of the latter two genera. Pseudodinemasporiumbore conidia morphologically similar to those of Dinemasporiumbut was differentiated from the latter by the conidiomata, which was composed of a well developed peridial structure. A total of 12 new species, namely three in Neopseudolachnella(N. acutispora, N. magnispora, N. uniseptata), one in Pseudodinemasporium(P. fabiforme) and eight in Pseudolachnella(P. asymmetrica, P. botulispora, P. brevicoronata, P. campylospora, P. complanata, P. falcatispora, P. fusiformisand P. pachyderma) are described and illustrated.

Electrical coherent manipulation of a quadrupolar-split nuclear spin ensemble in a GaAs quantum well (QW) with an rf electric field is demonstrated by the optical time-resolved Kerr rotation technique. Rabi oscillations and phase control between two spin-3/2 states are demonstrated by nuclear electric resonance in a gated GaAs QW device. This enables us to achieve coherent control of geometrically specified nuclear spins.

We investigated the magnetic field dependence of quadrupolar splitting and phase relaxation time of nuclear spins in an n-GaAs/AlGaAs (110) quantum well (QW) by optically detected nuclear magnetic resonance (NMR). The NMR spectra show large quadrupolar splitting induced by an internal field gradient in the QW epilayer. At lower magnetic fields, the quadrupolar splitting become much enhanced, resulting in the appearance of the second order magnetic field dependence of the quadrupole interaction in the NMR spectra. It is also shown that the intrinsic coherence time and the effective coherence time for resonant transitions become shorter as a result that the energy splitting between the two levels becomes small and incoherent transition is occurred by irradiation of an rf magnetic field.