1. A randomised study of hydro-jet vs. needle injection for lifting colorectal lesions prior to endoscopic resection.
- Author
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Cipolletta, L., Bianco, M.A., Garofano, M.L., Meucci, C., Piscopo, R., Cipolletta, F., Salerno, R., Sansone, S., and Rotondano, G.
- Subjects
ENDOSCOPIC retrograde cholangiopancreatography ,COLON injuries ,COLON surgery ,PRECANCEROUS conditions ,CAUTERY ,CONNECTIVE tissues ,ENDOSCOPIC surgery ,PATIENTS - Abstract
Abstract: Background: Submucosal lifting of lesions prior to endoscopic resection is crucial to reduce complications and improve the technical feasibility of the procedure. Aim: To compare a self-assembled hydro-jet system vs. standard needle injection for tissue elevation prior to endoscopic resection of colorectal lesions. Methods: Randomised study performed at a single tertiary care institution. Consecutive patients with colonoscopic diagnosis of sessile polyps or non-polypoid lesions >5mm or laterally spreading tumours. Outcome measures: successful elevation, time to proper elevation, completeness of excision, cautery damage, and general histological diagnostic quality (blinded pathologic assessment). Results: 79 patients were randomised to hydro-jet (40 patients, group A) and needle (39 patients, group B) elevation. Successful elevation was achieved in 97.5% and 94.8%, respectively. Time to proper elevation was 8±5s vs. 18±3s (p <0.05). In group A, histology showed selective accumulation of fluid in the submucosa with intact collagen fibres. Damage to muscularis mucosa was never noted in the specimens of group A and in 7 cases of group B (p <0.01). Artefacts from “cautery effect” were very limited. Radial margins of resection could be adequately evaluated in all cases and were negative. Conclusions: The hydro-jet system is as effective and safe as standard needle injection for tissue elevation prior to endoscopic resection of colorectal lesions, but it is significantly faster. [Copyright &y& Elsevier]
- Published
- 2010
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