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8 results on '"Rojas-Castro, Daniela"'

1. Daily and on-demand HIV pre-exposure prophylaxis with emtricitabine and tenofovir disoproxil (ANRS PREVENIR): a prospective observational cohort study

Author

Molina, Jean-Michel, Ghosn, Jade, Assoumou, Lambert, Delaugerre, Constance, Algarte-Genin, Michèle, Pialoux, Gilles, Katlama, Christine, Slama, Laurence, Liegeon, Geoffroy, Beniguel, Lydie, Ohayon, Michel, Mouhim, Hanane, Goldwirt, Lauriane, Spire, Bruno, Loze, Bénédicte, Surgers, Laure, Pavie, Juliette, Lourenco, Jérémy, Ben-Mechlia, Mohamed, Le Mestre, Soizic, Rojas-Castro, Daniela, and Costagliola, Dominique

Abstract

There are few data available regarding the use of on-demand pre-exposure prophylaxis (PrEP) for HIV prevention. We aimed to assess PrEP effectiveness, adherence, and safety in adults using daily or on-demand PrEP.

Published
2022
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2. HIV pre-exposure prophylaxis for men who have sex with men in west Africa: a multicountry demonstration study

Author

Laurent, Christian, Dembélé Keita, Bintou, Yaya, Issifou, Le Guicher, Gwenvael, Sagaon-Teyssier, Luis, Agboyibor, Mawuényégan K, Coulibaly, Alou, Traoré, Issa, Malan, Jean-Baptiste, De Baetselier, Irith, Eubanks, August, Riegel, Lucas, Rojas Castro, Daniela, Fayé-Ketté, Hortense, Koné, Amadou, Diandé, Souba, Dagnra, Claver A, Serrano, Laetitia, Diallo, Fodié, Mensah, Ephrem, Dah, Ter Tiero E, Anoma, Camille, Vuylsteke, Bea, Spire, Bruno, Laurent, Christian, Yaya, Issifou, Ouedraogo, Sayouba, Granouillac, Bruno, Le Guicher, Gwenvael, Serrano, Laetitia, Peeters, Martine, Couderc, Clotilde, Spire, Bruno, Sagaon-Teyssier, Luis, Mora, Marion, Maradan, Gwenaëlle, Bourrelly, Michel, Mimi, Mohamed, Berenger, Cyril, Boyer, Sylvie, Rojas Castro, Daniela, Riegel, Lucas, Palvadeau, Paméla, Vuylsteke, Bea, De Baetselier, Irith, Reyniers, Thijs, Dembélé Keita, Bintou, Diallo, Fodié, Coulibaly, Alou, Maïga, Alassane Kader, Camara, Drissa, Diarra, Mahamadou, Ouologuem, Aly, Sangaré, Naboh, Keita, Abdoul Aziz, Cissé, Oumar, Traoré, Fodé, Ouary, Bréhima Abdrahamane, Kanta, Ibrahima, Anoma, Camille, Malan, Jean-Baptiste, Kotchi, Rachelle, Aka, Niamkey Thomas, Lokrou, Kpassou Julien, Coulibaly, Noufo Hamed, Koffi, Ekissi Jean Armel, N'guessan, Dibi Frédéric, Babo Yoro, Stéphane-Alain, Cissé, Adama, Dah, Ter Tiero Elias, Traoré, Issa, Rajaonarivelo, Camille, Ouedraogo, Fayçal Rodrique, Ouedraogo, Joseph, Coulibaly, Christian, Ouedraogo, Mamadou, Ilboudo, Ousseni, Traoré, Abdoulazziz, Comsiambo, Honoré, Mensah, Ephrem, Agboyibor, Mawuényégan Kouamivi, Attisso, Anani, Kokouba, Anouwarsadat, Badjassim, Aléda Mawuli, Agbomadji, Kouakou Kokouvi Selom, Attiogbe, Messan, Yaka, Kossi Jeff, Ekon, Agbégnigan Lorette, Bimba, Julien, Dagnra, Claver Anoumou, and Tegueni, Kokou Dominique

Abstract

HIV pre-exposure prophylaxis (PrEP) data in men who have sex with men (MSM) in west Africa are essential to guide its large-scale implementation. We assessed the uptake of event-driven and daily PrEP, HIV incidence, and changes over time in sexual behaviours and prevalence of bacterial sexually transmitted infections (STIs) in MSM in Burkina Faso, Côte d'Ivoire, Mali, and Togo.

Published
2021
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3. Impact of the early 2020 COVID-19 crisis and lockdown on PrEP use among men who have sex with men (MSM) in France

Author

Di Ciaccio, Marion, Villes, Virginie, Michels, David, Morel, Stéphane, Delabre, Rosemary M, Rojas Castro, Daniela, and Velter, Annie

Abstract

ObjectiveTo describe changes in pre-exposure prophylaxis (PrEP) use during and following the COVID-19 lockdown in France (March–May 2020) and identify the factors associated with PrEP discontinuation among men who have sex with men (MSM) after the lockdown.MethodsData from the, an anonymous, cross-sectional internet survey among MSM in July 2020, were analysed. Among respondents who were using PrEP prior to the lockdown, a binary logistic regression model was used to compare participants who were still taking PrEP (current PrEP users) with those who were not taking PrEP at the time of the survey (former PrEP users).ResultsAmong 8345 respondents, 946 were PrEP users before the lockdown, of whom 58.8% (n=556) reported stopping PrEP during the lockdown and 15.4% (n=146) were not using PrEP at the time of the survey. Among the 556 who stopped PrEP during lockdown, 86.5% (n=481) reported no sexual activity; 76.8% (n=427) restarted PrEP after lockdown. Former PrEP users were more likely to be younger, not living with a stable male sexual partner, report moderate anxiety, report increased psychoactive drug use during the lockdown, and report not having tested for HIV or STI since the end of the lockdown because they did not know where to go, preferred to wait or for another reason. Reporting fewer male sexual partners in the last 6 months was also significantly associated with being a former PrEP user.ConclusionsMSM adapted PrEP use to their sexual activity during and after the French lockdown. After the lockdown, discontinued PrEP occurred more often among MSM who had fewer sexual partners and had mental health vulnerabilities. These factors could also be predictive of PrEP discontinuation in a more general context. PrEP users should be informed on how to safely stop/start PrEP and on the use of other prevention tools to reduce potential risk exposure during PrEP discontinuation.

Published
2022
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4. On-demand pre-exposure prophylaxis with tenofovir disoproxil fumarate plus emtricitabine among men who have sex with men with less frequent sexual intercourse: a post-hoc analysis of the ANRS IPERGAY trial

Author

Antoni, Guillemette, Tremblay, Cécile, Delaugerre, Constance, Charreau, Isabelle, Cua, Eric, Rojas Castro, Daniela, Raffi, François, Chas, Julie, Huleux, Thomas, Spire, Bruno, Capitant, Catherine, Cotte, Laurent, Meyer, Laurence, Molina, Jean-Michel, Aboulker, Jean-Pierre, Bajos, Nathalie, Baril, Jean-Guy, Besnier, Michel, Binesse, Johan, Carette, Diane, Cattin, Grégoire, Chéret, Antoine, Chidiac, Christian, Choucair, Elias, Delfraissy, Jean-François, Demoulin, Baptiste, Diallo, Alpha, Durant-Zaleski, Isabelle, Doré, Véronique, Etien, Nicolas, Euphrasie, Françoise, Fonsart, Julien, Foubert, Valérie, Gibowski, Séverine, Girard, Gabriel, Guillon, Brigitte, Le Mestre, Soizic, Lert, France, Leturque, Nicolas, Lorente, Nicolas, Mennecier, Anaïs, Morin, Michel, Netzer, Emmanuelle, Otis, Joanne, Pasquet, Armelle, Peytavin, Gilles, Pialoux, Gilles, Préau, Marie, Rabian, Cécile, Rozenbaum, Willy, Sagaon-Teyssier, Luis, Saïdi, Yacine, Saouzanet, Marine, Simon, Marie-Christine, Suzan-Monti, Marie, Thompson, David, Timsit, Julie, Trottier, Benoît, and Wainberg, Mark

Abstract

ANRS IPERGAY found that on-demand pre-exposure prophylaxis (PrEP) with oral tenofovir disoproxil fumarate plus emtricitabine was associated with an 86% relative reduction of HIV-1 incidence compared with placebo among men who have sex with men at high risk of HIV. We aimed to investigate whether on-demand PrEP was similarly effective among individuals with lower exposure to HIV risk.

Published
2020
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5. Changes in risky sexual behaviours among West African MSM enrolled in a quarterly HIV testing and counselling prevention programme (CohMSM ANRS 12324 – Expertise France)

Author

Coulaud, Pierre-Julien, Sagaon-Teyssier, Luis, Mimi, Mohamed, Maradan, Gwenae¨lle, Mora, Marion, Bourrelly, Michel, Dembélé Keita, Bintou, Keita, Abdoul Aziz, Anoma, Camille, Yoro, Stéphane-Alain Babo, Dah, Elias Ter Tiero, Coulibaly, Christian, Mensah, Ephrem, Agbomadji, Selom, Palvadeau, Pamela, Bernier, Adeline, Rojas Castro, Daniela, Couderc, Clotilde, Laurent, Christian, and Spire, Bruno

Abstract

ObjectivesWhether regular HIV testing and counselling reduce risky sexual behaviours in African men who have sex with men (MSM) is still a matter for debate. We aimed to identify behavioural trajectories based on HIV risk exposure (HRE) and factors affecting their evolution.MethodsData were collected from 621 HIV-negative West African MSM (Mali, Cote d'Ivoire, Burkina Faso and Togo) included in a community-based cohort providing quarterly HIV testing and counselling. Sociobehavioural data were collected every 6 months. HRE was defined as reporting inconsistent condom use during receptive anal sex with male partners of unknown HIV status in the previous 6 months. Using 18-month follow-up data, group-based trajectory modelling helped identify behavioural trajectories and determine the factors associated with their evolution. HIV seroconversions (n=67) were specified in each group trajectory.ResultsTwo distinct group trajectories were identified: medium-risk exposure MSM (ME-MSM) (61%, 6.4% of whom having seroconverted) and high-risk exposure MSM (HE-MSM) (39%, 17.5% of whom having seroconverted). A significant declining trend in the probability of reporting HRE over time ((95% CI)) was observed for HE-MSM (from 0.59 (0.48 to 0.70) at M0 to 0.31 (0.22 to 0.41) at M18), while it remained constant for ME-MSM (0.034 (0.0 to 0.079)). This can be explained by a progressive use of risk reduction strategies (less receptive anal sex, better knowledge of their partners’ status and increasing condom use). Being younger, living in Burkina Faso, self-considering both a man and a woman and reporting a higher level of depression were all associated with HE membership. Among HE-MSM, HRE was higher in those practising transactional or group sex and those experiencing psychological harassment.ConclusionsQuarterly HIV testing and counselling seem to reduce risky sexual behaviours in HIV-negative MSM at greatest risk of infection. Specific support for young MSM, focusing on identity and mental health, is needed to strengthen HIV prevention in West African MSM.

Published
2020
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6. Resilience outcomes and associated factors among workers in community-based HIV care centres during the Covid-19 pandemic: A multi-country analysis from the EPIC program

Author

Di Ciaccio, Marion, Lorente, Nicolas, Villes, Virginie, Maxence, Axel Akpaka, Vargas Pelaez, Claudia Marcela, Guillen, José Rafael, Castillo, Ingrid, Folch, Cinta, Diagne, Rokhaya, Riegel, Lucas, Delabre, Rosemary M., and Rojas Castro, Daniela

Abstract

•Little is known regarding mental health and resilience outcomes among Community Health Workers (CHW).•CHW showed a normal or high level of resiliency during the COVID-19 crisis.•Self-efficacy, through training of COVID −19 prevention, was associated with the resilience.•Greater support should be provided for CHW in the future health crises.

Published
2023
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7. Efficacy, safety, and effect on sexual behaviour of on-demand pre-exposure prophylaxis for HIV in men who have sex with men: an observational cohort study

Author

Molina, Jean-Michel, Charreau, Isabelle, Spire, Bruno, Cotte, Laurent, Chas, Julie, Capitant, Catherine, Tremblay, Cecile, Rojas-Castro, Daniela, Cua, Eric, Pasquet, Armelle, Bernaud, Camille, Pintado, Claire, Delaugerre, Constance, Sagaon-Teyssier, Luis, Mestre, Soizic Le, Chidiac, Christian, Pialoux, Gilles, Ponscarme, Diane, Fonsart, Julien, Thompson, David, Wainberg, Mark A, Doré, Veronique, Meyer, Laurence, Meyer, L, Capitant, C, Charreau, I, Netzer, E, Leturque, N, Binesse, J, Foubert, V, Saouzanet, M, Euphrasie, F, Carette, D, Guillon, B, Saïdi, Y, Aboulker, J P, Spire, B, Suzan, M, Cattin, G, Demoulin, B, Sagaon-Teyssier, L, Lorente, N, Doré, V, Choucair, E, Le Mestre, S, Mennecier, A, Etien, N, Simon, M C, Diallo, A, Gibowski, S, Delfraissy, J F, Thompson, D, Sas, J, Pankovitch, J, Klein, M, Anis, A, Molina, Jean-Michel, Wainberg, Mark A, Trottier, Benoit, Tremblay, Cécile, Baril, Jean-Guy, Pialoux, Gilles, Cotte, Laurent, Chéret, Antoine, Pasquet, Armelle, Cua, Eric, Besnier, Michel, Rozenbaum, Willy, Chidiac, Christian, Delaugerre, Constance, Bajos, Nathalie, Timsit, Julie, Peytavin, Gilles, Fonsart, Julien, Durand-Zaleski, Isabelle, Meyer, Laurence, Aboulker, Jean-Pierre, Spire, Bruno, Suzan-Monti, Marie, Girard, Gabriel, Castro, Daniela Rojas, Préau, Marie, Morin, Michel, Thompson, David, Capitant, Catherine, Mennecier, Anaïs, Choucair, Elias, Doré, Véronique, Simon, Marie-Christine, Charreau, Isabelle, Otis, Joanne, Lert, France, Diallo, Alpha, Gibowski, Séverine, and Rabian, Cecile

Abstract

Data for on-demand pre-exposure prophylaxis (PrEP) are scarce. We implemented a cohort study to assess its efficacy, safety, and effect on sexual behaviour.

Published
2017
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8. Assessment of mental health outcomes and associated factors among workers in community-based HIV care centers in the early stage of the COVID-19 outbreak in Mali

Author

Sagaon-Teyssier, Luis, Kamissoko, Aliou, Yattassaye, Adam, Diallo, Fodié, Rojas Castro, Daniela, Delabre, Rosemary, Pouradier, Fabrice, Maradan, Gwenaëlle, Bourrelly, Michel, Cissé, Mamadou, Vidal, Laurent, Keïta, Bintou Dembélé, and Spire, Bruno

Abstract

•Malian healthcare workers presented mental disorders in the early stage of COVID-19.•Nurses were at lower risk of mental health disorders than other worker categories.•Women were at greater risk of mental health disorders than men.•A lack of protection equipment and nurses was associated with mental disorders.

Published
2020
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