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Remembering the outcomes of past experiences allows us to generate future expectations and shape selection in the long-term. A growing number of studies has shown that learned positive reward values impact spatial memory-based attentional biases on perception. However, whether memory-driven attentional biases extend to punishment-related values has received comparatively less attention. Here, we manipulated whether recent spatial contextual memories became associated with successful avoidance of punishment (potential monetary loss). Behavioral and electrophysiological measures were collected from 27 participants during a subsequent memory-based attention task, in which we tested for the effect of punishment avoidance associations. Punishment avoidance significantly amplified effects of spatial contextual memories on visual search processes within natural scenes. Compared to non-associated scenes, contextual memories paired with punishment avoidance lead to faster responses to targets presented at remembered locations. Event-related potentials elicited by target stimuli revealed that acquired motivational value of specific spatial locations, by virtue of their association with past avoidance of punishment, dynamically affected neural signatures of early visual processing (indexed by larger P1 and earlier N1 potentials) and target selection (as indicated by reduced N2pc potentials). The present results extend our understanding of how memory, attention, and punishment-related mechanisms interact to optimize perceptual decision in real world environments.

The main objective of this study is to evaluate the effect of heavy drinking on alcohol-related injuries.

Abstract: Objective: To determine the prevalence of medicine consumption among Spanish university students and its association with alcohol, tobacco and cannabis consumption. Method: We carried out a cohort study among Spanish university students (n = 2,700). Consumption of medicines during the previous 15 days, risky alcohol use, and tobacco and cannabis consumption were measured using questionnaire. Logistic regression models were generated using consumption of medicines as dependent variables at the beginning of the study and for a 2-year follow-up. Results: A multivariate logistic regression model showed at the beginning of the study that being female (OR = 1.71), living away from home (OR = 1.35) and being a smoker (OR = 1.40) are associated with consumption of medicines. Furthermore, the model shows a significant interaction between risky alcohol use and cannabis consumption (OR = 2.00). The 2-year follow-up shows that only being female (OR = 1.44) and risky alcohol use (OR = 1.36) are associated with the considered dependent variable. Conclusions: Our results reveal a very high intake of medicines among university students; most of them are without a medical prescription. Probably, this consumption of medicines is another form of poly-consumption of drugs.