Search

Surgical repair of sinus venosus defects with partial anomalous pulmonary venous connection (PAPVC) to the superior vena cava (SVC) has been associated with venous return obstructions, and sinus node dysfunction. We aimed to evaluate the safety of four different surgical procedures, for repair of sinus venosus defects with PAPVC, in 23 adult patients, adapted to each patient's specific anatomy assessed by 3D computed tomography. Between March 2010 and May 2019, we performed anatomic repair of sinus venosus defects with a single patch (n = 6; 26.1%), 2-patch (n = 9; 39.1%), Warden (n = 3; 13%), or modified Warden procedure with reconstruction of the divided SVC using a PTFE conduit (n = 5; 21.7%) (Fig. 1). Median age was 40 years [range, 15 to 73 years]. Main associated procedures were: creation of atrial septal defect (n = 1), tricuspid valvuloplasty (n = 2), tricuspid valve replacement (n = 1), pulmonary valve replacement (n = 1), monoblock "cut and sew" of pulmonary veins and superior vena cava (n = 1). Follow-up was 3.26 years [range, 2 months to 10 years]. There were no mortality and no obstruction of SVC and pulmonary veins at the time of discharge and during follow-up. Aortic clamping was shorter (60 ± 39 min) with the single patch technique and longer (112 ± 31 min) with the modified Warden procedure. Nineteen patients (82.6%) had regained sinus rhythm at discharge; a patient with paroxysmal atrial fibrillation had regained a sinus rhythm after the "cut and sew" isolation technique of the superior vena cava and pulmonary veins. All patients were NYHA 1. PAPVC can safely be performed with an appropriate technique, and low morbidity. The single patch technique, when anatomically possible, offers good results but now competes with transcatheter correction. When PAPVC is far from the SVC-right atrium junction, the modified Warden procedure offers an effective and obligatory surgical repair, without any increase in complications. [ABSTRACT FROM AUTHOR]

The difference between extreme Tetralogy of Fallot (T4F) and pulmonary atresia with ventricle septal defect (PA/VSD) is the anterograde pulmonary blood flow. It is speculated that the association of modified Blalock-Taussig shunt (mBTs) and additional pulmonary blood flow favours shunt thrombosis but promotes better pulmonary arterial (PA) growth. This study sought to compare (PA) growth after mBTs shunt between T4F and AP/VSD. From 1995 to 2018, 79 mBTs were performed in infants (< 1 years), 45 for T4F and 34 for AP/VSD. Using a 1:1 propensity score match analysis, 38 patients were included (n = 19 in each group). The primary outcome was operative mortality, mBTs thrombosis, and PA growth. After matching, the preoperative Nakata was similar (101 ± 8 mm2/m2in T4F; 106 ± 8 in AP/VSD P = 0.75). The age and weight were similar (24,3 ± 5 days, 3.3 ± 0.5 kg in T4F; 24,15 ± 4, 3.3 ± 0.9 in AP/VSD P = 0.84 and P = 0.77 respectively). The mBTs size was similar (4.15 ± 0.5 mm in T4F; 4.3 ± 0.5 in PA/VSD P = 0.35). There was no difference in in-hospital mortality (n = 0, in T4F; n = 2, 11% in AP/VSD, P = 0.14) and mBTs thrombosis (3,16% in T4F; 2,11% in AP/VSD, P = 0.18). The time to extubation tended to be longer in T4F (5 ± 1days vs. 2 ± 1 P = 0.06). The left and right PA diameter at time of biventricular repair were similar (7.5 ± 0.5 mm, 7 ± 0.2 in T4F; 8.1 ± 0.7 mm, 7 ± 1 in AP/VSD P = 0.43 and P = 0.78, Fig. 1) and the Nakata delta (112 ± 23 mm2/m2in T4F; 110 ± 17 in AP/VSD P = 0.78). Median time to complete repair was the same in the PA/VSD (12.26 [3.9-25] months) compared with T4F (9.7 [6.2–41.1] months) P = 0.87). The interstage reintervention were similar (3.16% in T4F; 4.22% in AP/VSD , P = 0.9). Anterograde blood flow with mBTs did not increase the risk of mBTs thrombosis. We could not show benefit of anterograde blood flow with mBTS versus mBTS for pulmonary arteries growth. Anterograde blood flow did increase the time to extubation, probably by increasing total pulmonary blood flow. [ABSTRACT FROM AUTHOR]