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The treatment of patients with immune nephropathies is discussed: rapidly progressive nephritis, lupus nephropathy, Wegener granulomatosis, Goodpasture syndrome, Schonlein-Henoch nephritis. A combined treatment of plasmapheresis and imminosuppressants is applied. A definite result, specially with the cases of Wegener granulomatosis, is registered for certain number of the patients. Together with the usual tests: CIC, immunoglobulins, complement, etc. a method for controlling of the detoxic efficiency of the treatment is suggested. This is a biologic method-the level of paramecium caudatum in media from patients' plasma is registered in relation to time. After plasmapheresia the life of paramecium caudatum is considerably prolonged.

The influence of the caprolactam quality on the characteristics of polycaproamide thereof was elucidated.

Well-known mineral baths in Bulgaria, ‘Hissarya’, are described. Their existence dates back more than 25 centuries. ‘Hissarya’ is an Arabic word meaning ‘siege of a castle’. Remains of castle walls are the symbol of ‘Hissarya’ today. Every year more than 100,000 patients from Bulgaria and other countries visit ‘Hissarya’. From the time of the Thracians and the Roman Empire until now renal stones have been successfully treated by drinking the mineral water and by taking baths. The Roman Emperor Septimius Severus (193–211) visited ‘Hissarya’ every spring to treat his renal disease.