242 results on '"Muris, P"'
Search Results
2. Hikikomori: jonge kluizenaars
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Muris, Peter
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- 2024
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3. One-piece endodontic crown fixed partial denture: Is it possible?
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Tribst, João Paulo M., Dal Piva, Amanda Maria de O., Muris, Joris, Kleverlaan, Cornelis J., and Feilzer, Albert J.
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Whether the replacement of a missing tooth with a fixed partial denture supported by an endodontically treated abutment could be improved with 1-piece endodontic crowns is unclear. The purpose of the study was to evaluate the mechanical behavior of a fixed partial denture (FPD) according to the preparation of the abutment teeth (1-piece endodontic crown or complete crown) in terms of stress magnitude in the prosthesis, cement layer, and tooth. A posterior model with 2 abutment teeth (first molar and first premolar) was modeled with a computer-aided design (CAD) software program for conducting a 3-dimensional finite element analysis (FEA). To replace the missing second premolar, the model was replicated in different possible FPDs according to the abutment preparation design (complete crown [Conventional], 2 1-piece endodontic crowns [EC]) or a 1-piece endodontic crown on one of the abutment teeth (first molar [ECM] and first premolar [ECP]) for a total of 4 designs. All FPDs were in lithium disilicate. The solids were imported to an analysis software program (ANSYS 19.2) in the standard for the exchange of product data (STEP) format. The mechanical properties were considered isotropic and the materials to show linear elastic and homogeneous behavior. An axial load (300 N) was applied at the occlusal surface of the pontic. The results were evaluated by colorimetric stress maps of von Mises and maximum principal stress in the prosthesis, maximum principal stress and shear stresses on the cement layer, and maximum principal stress in the abutment teeth. The von Mises stresses revealed that all FPD designs behaved similarly and that, considering the maximum principal stress criteria, the pontic was the most stressed region. For the cement layer, the combined designs presented an intermediate behavior, with the ECM more suitable to reducing the stress peak. The conventional preparation allowed less stress concentration in both teeth, and higher stress concentration in the premolar was observed with a 1-piece endodontic crown. The 1-piece endodontic crown decreased the risk of fracture failure. Considering the risk of debonding failure for the prosthesis, the 1-piece endodontic crown preparation was only able to decrease the failure risk when the EC design was used and when only the shear stress was considered. Performing 1-piece endodontic crown preparations to retain a 3-unit lithium disilicate FPD is an alternative to conventional complete crown preparations. [ABSTRACT FROM AUTHOR]
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- 2024
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4. Reshaping respiratory care: potential advances in inhaled pharmacotherapy in asthma
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Dierick, Boudewijn J.H., Eikholt, Amber A., van de Hei, Susanne J., Muris, Jean W.M., Kerstjens, Huib A.M., and van Boven, Job F.M.
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ABSTRACTIntroductionAsthma is a common disease with a global burden of 358 million patients. Despite improvements in pharmacological and non-pharmacological treatments, many patients still do not achieve complete asthma control. Therefore, innovative pharmacotherapy is important.Areas coveredFollowing a semi-structured search in Pubmed, an overview of advances in inhaled asthma therapy is provided, looking at innovations in digital inhalers, eco-friendly inhalers and novel inhaled biologic therapies, antibiotics and vaccines, as well as other potential novel asthma therapy targets.Expert opinionDigital inhalers, sending reminders and monitoring inhalation technique electronically, can support medication adherence and improve asthma control. To reduce the global warming potential of traditional aerosols used in pressurized metered-dose inhalers (HFA-134a, HFA-227ea), greener alternatives are under development (HFA-152a, HFO-1234ze) that are expected to be available by 2025. Current pharmacological advances in asthma therapy are mainly achieved by novel biologicals (anti-IgE, anti-IL5, anti-IL4/13, and anti-TSLP) targeting specific severe asthma phenotypes. While injection is the usual administration route for biologics and vaccines used in asthma, inhalation is an option being explored, although several (mainly formulation) challenges need to be overcome. Other potential novel future inhaled asthma therapies include anti-IL-33/ST2 biologicals and JAK inhibitors, all still requiring more clinical evidence.
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- 2024
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5. DIFFERENCES IN SHOOTING ACCURACY AND EFFICIENCY OF THE TOP WOMEN'S TEAMS AT THE 2021 TOKYO OLYMPIC GAMES.
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Sanja, Bajgorić, Muris, Đug, and Nenad, Rađević
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HANDBALL ,NATIONAL sports teams ,OLYMPIC Games ,SPORTS - Abstract
This study is established on the aim to analyse a game and determine differences in a shot efficacy in an offence the woman's handball national teams at the Olympic games in Tokyo 2021. Four national teams were analysed: France, Russia, Norway and Sweden. To analyse a game in the offence, 12 variables were used: total number of shots (sut_uk), efficient number of shots (sut_usp), total number of shots from 6 meters (sut_m6_uk), efficient number of shots from 6 meters (sut_m6_us), total number of shots from wings (sut_kril_uk), the efficient number of shots from wings (sut_kr_us), total number of shots from 9 meters (sut_m9_uk), efficient number of shots from 9 meters (sut_m9_us), total number of shots from 7 meters (sut_m7_uk), efficient number of shots from 7 meters (sut_m7_us), total number of fast centres (brzc_uk) and total number of efficient fast centres (sut_brzc_us). All national teams had the approximal number of efficient shots on a goal. The highest number of efficient shots from 6 m had the French and Norwegian national teams. From the wing position, the highest number of efficient shots had the Norwegian national team, while the lowest number of efficient goals from the wing position had the Russian national team. The Norwegian and French national teams were approximately efficient in the shot's realisation from 9 m. In a realisation of the fast centre, the Russian national team stands out with the highest number and the French national team had the lowest number of efficient shots. [ABSTRACT FROM AUTHOR]
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- 2023
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6. DIFFERENCES IN SHOOTING ACCURACY AND EFFICIENCY TRENDS OF THE BEST HANDBALL REPRESENTATIONS AT THE 2021 TOKYO OLYMPIC GAMES.
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Bajgorić, Sanja and Đug, Muris
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HANDBALL players ,OLYMPIC Games ,INFORMATION retrieval - Abstract
This study has been undertaken to perform the game analysis, to determine an efficacy difference in an offence of four first placed woman handball national teams at the Olympic games in Tokyo. One of the problems, which undergoes scientific research, is competition between teams and an efficacy in the mentioned sport. The performance of any technical element in the handball is impossible to perform without the adequate motoric ability, as well as the quality of the motoric ability is impossible to perform without the rational technique. In this study, based information were obtained from first THIRD handball national teams of France, Russia and Norway during eight matches at the Olympic games in Tokyo. The total of 12 offence's variables were obtained from 8 matches of woman's handball national teams and analysed: total number of shots (sut_uk), precise - efficient number of shots (sut_pre), total number of shots from 6 meters (sut_m6_uk), precise - efficient number of shots from 6 meters (sut_m6_pre), total number of shots from wings (sut_kril_uk), precise - efficient number of shots from wings (sut_kr_pre), total number of shots from 9 meters (sut_m9_uk), precise - efficient number of shots from 9 meters (sut_m9_pre), total number of shots from 7 meters (sut_m7_uk), precise - efficient number of shots from 7 meters (sut_m7_pre), total number of fast centres (brzc_uk) and total number of precise - accomplished fast centres (sut_brzc_pre). Based on the analysis in this study, it is evident that the game of national teams was based on shots from 9 m, shots from 6 m, and on the fast performance of the fast centre. By analysed results, could be concluded, that these variables significantly determinate the game in offence on this tournament. [ABSTRACT FROM AUTHOR]
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- 2022
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7. On Treatment of Some Physical Properties of Gas in Simulation of High-Voltage SF6Circuit Breakers
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Torlak, Muris, Čaluk, Samir, Hadžović, Belma Bosović, and Smajkić, Amer
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Simulation of unsteady flow of SF6gas in a simplified high-voltage circuit breaker model describing the nozzle, contacts and their nearest surrounding is presented. SF6is considered as viscous, compressible, real gas described by Redlich-Kwong model. Heat transfer is taken into account due to the gas compressibility. The heat source, triggered by the electric arc between the contacts, was out of the scope of the current research, thus it was not included in the simulations presented. Turbulence, caused by the gas viscosity, is described using realizable k-εmodel. In the simulation model, one of the contact sides – electrodes, is considered as moving at prescribed velocity. The part of the space ‘swept’ by the moving electrode is considered as the gas with imposed artificially increased viscosity in order to imitate the rigid body behaviour. Thus, no moving parts of the computational mesh are used in the model. The conservation equations of mass, momentum and energy, given in integral form, are solved using a finite-volume method on unstructured computational grids.
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- 2022
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8. DIFFERENCES OF SITUATIONAL AND MOTOR ABILITIES IN DEFENSE AT THE WORLD JUNIOR HANDBALL CHAMPIONSHIP.
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Bajgorić, Sanja and Đug, Muris
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MOTOR ability ,HANDBALL players ,JUMPING ,CHAMPIONSHIPS ,SPORTS events - Abstract
The research was conducted in order to determine the differences in situational-motor abilities in the defense of men's junior national teams at the 2013 World Handball Championship. Situational - motor abilities in the defense of the national team of Bosnia and Herzegovina in relation to the national teams of Croatia, France, Sweden and Spain were analyzed. The following variables were used to determine differences in defense: SKODEKUK / PR - total - average number of jumps in defense of the whole team, SKODUK / PR1 - total - average number of jumps in defense first player of defense, SKODUK / PR2 - total - average number of jumps in defense second defensive player, SKODUK / PR3 - total - average number of defensive jumps third defensive player, SKODUK / PR4 - total - average number of defensive jumps fourth defensive player, SKODUK / PR5 - total - average number of defensive jumps fifth defensive player and SKODUK / PR6 - total - average number of jumps in the sixth defense player. To determine the partial quantitative differences of variables, which measure the total and average number of attempts to perform an element in the area of situational - motor abilities in defense, we used the mean difference of mean (hereinafter MD), which calculated the average values of selected variables. The average values of variables for the assessment of situational - motor abilities in defense were also calculated. The variable SKODUK / PR4 - total - average number of jumps in the defense of the fourth player shows a statistically significant negative difference in the jumps in the defense of the fourth player between the fourth player in the defense of Bosnia and Herzegovina and the fourth player in the defense of Croatia and Sweden. In the variable SKODUK / PR6 - total - average number of jumps in the defense of the sixth defense player, a statistically significant negative difference can be seen between the sixth player in the defense of the national team of Bosnia and Herzegovina and the sixth player in the defense of Sweden. [ABSTRACT FROM AUTHOR]
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- 2021
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9. Introduction of Financial Settlement Among LFC Areas
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Bakalovic, Muris, Džizic, Merim, Erovic, Dženeta, and Šeremet, Mario
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Settlement of unintended deviation between scheduled and realized energy exchange among LFC (Load Frequency Control) areas used to be conducted through the energy compensation programs, where energy deviation from period of registration is compensated at a later stage period of compensation of unintended deviation. With the adoption of the Synchronous Area Framework Agreement (SAFA), the Regional Group for Continental Europe the methodology of accounting and financial settlement of unintended deviations FSKAR (Financial settlement k?f, ACE and ramping period) is defined. The FSKAR methodology defines necessary data for the calculation and determination of unintended deviation. The methodology defines the method of determining settlement prices. The paper describes the methodology of determining settlement prices, the method of data collection and validation, the method of calculation of deviations and other energy and financial quantities, and data exchange between entities.
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- 2022
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10. Dementia risk reduction in the general practice: a proof‐of‐concept study evaluating the use of a brain health promotion smartphone app.
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Van Asbroeck, Stephanie, Köhler, Sebastian, Muris, Jean W.M., van Boxtel, Martin P.J., and Deckers, Kay
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Background: During the last decades, evidence supporting the relevance of brain health promotion and dementia risk reduction has considerably expanded (1). Currently, this evidence is sufficient to take public health action (2, 3). However, implemented interventions are still scarce, especially at a large scale. In the Netherlands, evidence‐based cardiovascular risk management is already implemented in primary care. Since there is a large overlap between modifiable risk factors for dementia and those for cardiovascular disease, discussing dementia risk reduction next to cardiovascular health in the general practice seems a feasible, first step towards future large‐scale implementation of dementia risk reduction strategies. Method: A proof‐of‐concept study is currently being conducted in ten general practices in the Netherlands in which 180 participants between 40 and 60 years old, with room for improvement on at least one modifiable risk factor, will have a consultation with their general practitioner or practice nurse. During this consultation, they will learn about brain health promotion and how they could personally improve their risk profile. Practices have been randomly allocated (1:1) to either provide the consultation only, or to additionally provide the participants with a brain health promotion smartphone app (i.e. MijnBreincoach). Result: Feasibility will be evaluated using validated questionnaires assessing knowledge on dementia risk reduction, health behavior, motivation, usability, satisfaction, and user experience with the smartphone app. Surveys will be administered before the consultation at the general practice and three months thereafter. Further, ten participants and four healthcare professionals will be invited for a qualitative interview to get a more in‐depth view of the intervention's feasibility. Conclusion: Discussing dementia risk reduction in the general practice may constitute a feasible and effective, scalable approach towards dementia risk reduction. Results of the study are expected by July 2023. References 1. Livingston G, Huntley J, Sommerlad A, et al. Dementia prevention, intervention, and care: 2020 report of the Lancet Commission. Lancet. 2020;396(10248):413‐46. 2. World Health Organization. Risk reduction of cognitive decline and dementia: WHO guidelines. Geneva; 2019. 3. Steyaert J, Deckers K, Smits C, et al. Putting primary prevention of dementia on everybody's agenda. Aging Ment Health. 2020:1‐5. [ABSTRACT FROM AUTHOR]
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- 2023
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11. Guideline for the diagnosis and treatment of Faecal Incontinence—A UEG/ESCP/ESNM/ESPCG collaboration
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Assmann, Sadé L., Keszthelyi, Daniel, Kleijnen, Jos, Anastasiou, Foteini, Bradshaw, Elissa, Brannigan, Ann E., Carrington, Emma V., Chiarioni, Giuseppe, Ebben, Liora D. A., Gladman, Marc A., Maeda, Yasuko, Melenhorst, Jarno, Milito, Giovanni, Muris, Jean W. M., Orhalmi, Julius, Pohl, Daniel, Tillotson, Yvonne, Rydningen, Mona, Svagzdys, Saulius, Vaizey, Carolynne J., and Breukink, Stephanie O.
- Abstract
The goal of this project was to create an up‐to‐date joint European clinical practice guideline for the diagnosis and treatment of faecal incontinence (FI), using the best available evidence. These guidelines are intended to help guide all medical professionals treating adult patients with FI (e.g., general practitioners, surgeons, gastroenterologists, other healthcare workers) and any patients who are interested in information regarding the diagnosis and management of FI. These guidelines have been created in cooperation with members from the United European Gastroenterology (UEG), European Society of Coloproctology (ESCP), European Society of Neurogastroenterology and Motility (ESNM) and the European Society for Primary Care Gastroenterology (ESPCG). These members made up the guideline development group (GDG). Additionally, a patient advisory board (PAB) was created to reflect and comment on the draft guidelines from a patient perspective. Relevant review questions were established by the GDG along with a set of outcomes most important for decision making. A systematic literature search was performed using these review questions and outcomes as a framework. For each predefined review question, the study or studies with the highest level of study design were included. If evidence of a higher‐level study design was available, no lower level of evidence was sought or included. Data from the studies were extracted by two reviewers for each predefined important outcome within each review question. Where possible, forest plots were created. After summarising the results for each review question, a systematic quality assessment using the GRADE (Grading of Recommendations, Assessment, Development and Evaluations) approach was performed. For each review question, we assessed the quality of evidence for every predetermined important outcome. After evidence review and quality assessment were completed, recommendations could be formulated. The wording used for each recommendation was dependent on the level of quality of evidence. Lower levels of evidence resulted in weaker recommendations and higher levels of evidence resulted in stronger recommendations. Recommendations were discussed within the GDG to reach consensus. These guidelines contain 45 recommendations on the classification, diagnosis and management of FI in adult patients. These multidisciplinary European guidelines provide an up‐to‐date comprehensive evidence‐based framework with recommendations on the diagnosis and management of adult patients who suffer from FI.
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- 2022
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12. How does portfolio use affect self-regulated learning in clinical workplace learning: What works, for whom, and in what contexts?
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van der Gulden, Rozemarijn, Timmerman, Angelique, Muris, Jean W. M., Thoonen, Bart P. A., Heeneman, Sylvia, and Scherpbier-de Haan, Nynke D.
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Introduction: Portfolio use to support self-regulated learning (SRL) during clinical workplace learning is widespread, but much is still unknown regarding its effectiveness. This review aimed to gain insight in the extent to which portfolio use supports SRL and under what circumstances. Methods: A realist review was conducted in two phases. First, stakeholder interviews and a scoping search were used to formulate a program theory that explains how portfolio use could support SRL. Second, an in-depth literature search was conducted. The included papers were coded to extract context–mechanism–outcome configurations (CMOs). These were synthesized to answer the research question. Results: Sixteen papers were included (four fulfilled all qualitative rigor criteria). Two primary portfolio mechanisms were established: documenting as a moment of contemplation (learners analyze experiences while writing portfolio reports) and documentation as a reminder of past events (previous portfolio reports aid recall). These mechanisms may explain the positive relationship between portfolio use and self-assessment, reflection, and feedback. However, other SRL outcomes were only supported to a limited extent: formulation of learning objectives and plans, and monitoring. The partial support of the program theory can be explained by interference of contextual factors (e.g., system of assessment) and portfolio-related mechanisms (e.g., mentoring). Discussion: Portfolio research is falling short both theoretically—in defining and conceptualizing SRL—and methodologically. Nevertheless, this review indicates that portfolio use has potential to support SRL. However, the working mechanisms of portfolio use are easily disrupted. These disruptions seem to relate to tensions between different portfolio purposes, which may undermine learners’ motivation.
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- 2022
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13. A professional knowledge base for collaborative reflection education: a qualitative description of teacher goals and strategies
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van Braak, Marije, Veen, Mario, Muris, Jean, van den Berg, Pieter, and Giroldi, Esther
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Introduction: For several decades, educational experts have promoted reflection as essential to professional development. In the medical setting, collaborative reflection has gained significant importance across the curriculum. Collaborative reflection has a unique edge over individual reflection, but many medical teachers find facilitating group reflection sessions challenging and there is little documentation about the didactics of teaching in such collaborative reflection settings. To address this knowledge gap, we aim to capture the professional knowledge base for facilitating collaborative reflection by analyzing the formal and perceived goals and strategies of this practice. Methods: The professional knowledge base consists of formal curricular materials as well as individual teacher expertise. Using Template Analysis, we analyzed the goals and strategies of collaborative reflection reported in institutional training documents and video-stimulated interviews with individual teachers across all Dutch general practitioner training institutes. Results: The analysis resulted in a highly diverse overview of educational goals for residents during the sessions, teacher goals that contribute to those educational goals, and a myriad of situation-specific teacher strategies to accomplish both types of goals. Teachers reported that the main educational goal was for residents to learn and develop and that the teachers’ main goal was to facilitate learning and development by ensuring everyone’s participation in reflection. Key teacher strategies to that end were to manage participation, to ensure a safe learning environment, and to create conditions for learning. Discussion: The variety of strategies and goals that constitute the professional knowledge base for facilitating collaborative reflection in postgraduate medical education shows how diverse and situation-dependent such facilitation can be. Our analysis identifies a repertoire of tools that both novice and experienced teachers can use to develop their professional skill in facilitating collaborative reflection.
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- 2022
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14. Identifying Entrustable Professional Activities for Shared Decision Making in Postgraduate Medical Education: A National Delphi Study.
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Baghus, Anouk, Giroldi, Esther, Muris, Jean, Stiggelbout, Anne, van de Pol, Marjolein, Timmerman, Angelique, and van der Weijden, Trudy
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- 2021
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15. IDENTIFICATION OF DIFFERENCES OF PRELIMINARY GROUPS OF THE 2020 WORLD HANDBALL CHAMPIONSHIP.
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Bajgorić, Sanja and Đug, Muris
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HANDBALL competitions ,HANDBALL players ,TOURNAMENTS ,WORLD championships - Abstract
The research was conducted with the purpose to identify differences in the efficiency of shooting of the national teams of the preliminary group of the 2020 World Handball Championship. In total, twelve teams were analysed: Montenegro, Serbia, Northern Macedonia, Ucraine, Latvia, Netherlands, Bosnia and Herzegovina, France, Denmark, Russia, Switzerland and Poland, which left the tournament after the preliminary phase and played three games. The analysed variables were: Shots of the positional attack (total number of shots, total successful shots, percentage of shots), Shots with a player more (total number of shots, total successful shots, percentage of shots), Shots with a player less (total number of shots, total successful shots, percentage of shots), Shots from nine meters (total number of shots, total successful shots, percentage of shots). The aim of this research was the identification of differences in the efficiency of shooting in the national teams of the preliminary group of the 2020 World Handball Championship. [ABSTRACT FROM AUTHOR]
- Published
- 2020
16. Efficacy and Safety of Peppermint Oil in a Randomized, Double-Blind Trial of Patients With Irritable Bowel Syndrome.
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Weerts, Zsa Zsa R.M., Masclee, Ad A.M., Witteman, Ben J.M., Clemens, Cees H.M., Winkens, Bjorn, Brouwers, Jacobus R.B.J., Frijlink, Henderik W., Muris, Jean W.M., De Wit, Niek J., Essers, Brigitte A.B., Tack, Jan, Snijkers, Johanna T.W., Bours, Andrea M.H., de Ruiter-van der Ploeg, Annieke S., Jonkers, Daisy M.A.E., and Keszthelyi, Daniel
- Abstract
Peppermint oil is frequently used to treat irritable bowel syndrome (IBS), despite a lack of evidence for efficacy from high-quality controlled trials. We studied the efficacy and safety of small-intestinal–release peppermint oil in patients with IBS and explored the effects of targeted ileocolonic-release peppermint oil. We performed a double-blind trial of 190 patients with IBS (according to Rome IV criteria) at 4 hospitals in The Netherlands from August 2016 through March 2018; 189 patients were included in the intent-to-treat analysis (mean age, 34.0 years; 77.8% female; 57.7% in primary care), and 178 completed the study. Patients were randomly assigned to groups given 182 mg small-intestinal–release peppermint oil, 182 mg ileocolonic-release peppermint oil, or placebo for 8 weeks. The primary endpoint was abdominal pain response, as defined by the US Food and Drug Administration: at least a 30% decrease in the weekly average of worst daily abdominal pain compared with baseline in at least 4 weeks. The co-primary endpoint was overall relief of IBS symptoms, as defined by the European Medicines Agency. Secondary endpoints included abdominal pain, discomfort, symptom severity, and adverse events. Abdominal pain response did not differ significantly between the peppermint oil and placebo groups: 29 of 62 patients in the small-intestinal–release peppermint oil group had a response (46.8%, P =.170 vs placebo), 26 of 63 patients in the ileocolonic-release peppermint oil group had a response (41.3%, P =.385 vs placebo), and 22 of 64 patients in the placebo group had a response (34.4%). We did not find differences among the groups in overall relief (9.7%, P =.317 and 1.6%, P =.351 vs 4.7% for placebo). The small intestinal peppermint oil did, however, produce greater improvements than placebo in secondary outcomes of abdominal pain (P =.016), discomfort (P =.020), and IBS severity (P =.020). Adverse events, although mild, were more common in both peppermint oil groups (P <.005). In a randomized trial of patients with IBS, we found that neither small-intestinal–release nor ileocolonic-release peppermint oil (8 weeks) produced statistically significant reductions in abdominal pain response or overall symptom relief, when using US Food and Drug Administration/European Medicines Agency recommended endpoints. The small-intestinal–release peppermint oil did, however, significantly reduce abdominal pain, discomfort, and IBS severity. These findings do not support further development of ileocolonic-release peppermint oil for treatment of IBS. Clinicaltrials.gov , Number: NCT02716285. [ABSTRACT FROM AUTHOR]
- Published
- 2020
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17. NATIONAL TEAMS RANKING BASED ON SITUATIONAL EFFICIENCY INDICATORS OF THE OFFENCE AT THE WORLD HARDBALL CHAMPIONSHIP.
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Bajgoric, Sanja, Dug, Muris, Bijedic, Nina, and Mededovic, Samra
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HANDBALL competitions ,NATIONAL sports teams ,HANDBALL players ,CHAMPIONSHIPS ,OFFENSIVE players - Abstract
This study was based on the 45 games of the 2013 World Junior Handball Championship in Bosnia and Herzegovina. The focus was on the determination of the difference in the scope of the situational efficiency of offence between national teams: Sweden, Spain, France, Croatia and Bosnia and Herzegovina. Following variables were analysed: KPKUK - total number of the contra offences and semi counter offences, ŠPNAUK - total number of shots from positional offence, NAUKM7 - total number of the 7m in offences, BRZNAUK - total number of the rapid offences, BRZCUK - total number of the fast centres, and five variables for assessment of the situational efficiency in successful offences: KPKUS - total number of the successful contra offences and semi counter offences, ŠPNAUS - total number of the successful shots from positional offence, NAUSM7 - total number of the successful 7m in offences, BRZNAUS - total number of the successful rapid offences, BRZCUS - total number of the successful fast centres. The aim of this study was to determine differences of the situational efficiency of analysed national teams, and to rank national teams by percentile of means using analysed variables. The game quality of the analysed national teams was determined on the results of the central and dispersion parameters and same analysed national teams were ranked on the obtained values of the parameters. [ABSTRACT FROM AUTHOR]
- Published
- 2019
18. United European Gastroenterology (UEG) and European Society for Neurogastroenterology and Motility (ESNM) consensus on functional dyspepsia
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Wauters, Lucas, Dickman, Ram, Drug, Vasile, Mulak, Agata, Serra, Jordi, Enck, Paul, Tack, Jan, Accarino, Anna, Barbara, Giovanni, Bor, Serhat, Coffin, Benoit, Corsetti, Maura, De Schepper, Heiko, Dumitrascu, Dan, Farmer, Adam, Gourcerol, Guillaume, Hauser, Goran, Hausken, Trygve, Karamanolis, George, Keszthelyi, Daniel, Malagelada, Carolin, Milosavljevic, Tomislav, Muris, Jean, O’Morain, Colm, Papathanasopoulos, Athanassos, Pohl, Daniel, Rumyantseva, Diana, Sarnelli, Giovanni, Savarino, Edoardo, Schol, Jolien, Sheptulin, Arkady, Smet, Annemieke, Stengel, Andreas, Storonova, Olga, Storr, Martin, Törnblom, Hans, Vanuytsel, Tim, Velosa, Monica, Waluga, Marek, Zarate, Natalia, and Zerbib, Frank
- Abstract
Functional dyspepsia (FD) is one of the most common conditions in clinical practice. In spite of its prevalence, FD is associated with major uncertainties in terms of its definition, underlying pathophysiology, diagnosis, treatment, and prognosis. A Delphi consensus was initiated with 41 experts from 22 European countries who conducted a literature summary and voting process on 87 statements. Quality of evidence was evaluated using the grading of recommendations, assessment, development, and evaluation (GRADE) criteria. Consensus (defined as >80% agreement) was reached for 36 statements. The panel agreed with the definition in terms of its cardinal symptoms (early satiation, postprandial fullness, epigastric pain, and epigastric burning), its subdivision into epigastric pain syndrome and postprandial distress syndrome, and the presence of accessory symptoms (upper abdominal bloating, nausea, belching), and overlapping conditions. Also, well accepted are the female predominance of FD, its impact on quality of life and health costs, and acute gastrointestinal infections, and anxiety as risk factors. In terms of pathophysiological mechanisms, the consensus supports a role for impaired gastric accommodation, delayed gastric emptying, hypersensitivity to gastric distention, Helicobacter pyloriinfection, and altered central processing of signals from the gastroduodenal region. There is consensus that endoscopy is mandatory for establishing a firm diagnosis of FD, but that in primary care, patients without alarm symptoms or risk factors can be managed without endoscopy. There is consensus that H. pyloristatus should be determined in every patient with dyspeptic symptoms and H. pyloripositive patients should receive eradication therapy. Also, proton pump inhibitor therapy is considered an effective therapy for FD, but no other treatment approach reached a consensus. The long‐term prognosis and life expectancy are favorable. A multinational group of European experts summarized the current state of consensus on the definition, diagnosis and management of FD. Current knowledge Functional dyspepsia is one of the most common conditions encountered in clinical practice.There is a lack of guidance for clinicians in guiding diagnosis and treatment of this prevalent condition.No treatments are currently approved for the treatment of functional dyspepsia in Europe. Functional dyspepsia is one of the most common conditions encountered in clinical practice. There is a lack of guidance for clinicians in guiding diagnosis and treatment of this prevalent condition. No treatments are currently approved for the treatment of functional dyspepsia in Europe. What is new here A Delphi panel consisting of 41 experts from 22 European countries established the level of consensus on 87 statements regarding functional dyspepsia.The statements reaching consensus serve to guide clinicians in recognizing, diagnosing and treating FD in clinical practice.Endoscopy is mandatory for establishing a firm diagnosis of functional dyspepsia D, but in primary care patients without alarm symptoms or risk factors can be managed without endoscopy.Helicobacter pyloristatus should be determined in every patient with dyspeptic symptoms and H. Pyloripositive patients should receive eradication therapy.Proton pump inhibitor‐therapy is considered an effective therapy for FD, but no other treatment approach reached consensus support. A Delphi panel consisting of 41 experts from 22 European countries established the level of consensus on 87 statements regarding functional dyspepsia. The statements reaching consensus serve to guide clinicians in recognizing, diagnosing and treating FD in clinical practice. Endoscopy is mandatory for establishing a firm diagnosis of functional dyspepsia D, but in primary care patients without alarm symptoms or risk factors can be managed without endoscopy. Helicobacter pyloristatus should be determined in every patient with dyspeptic symptoms and H. Pyloripositive patients should receive eradication therapy. Proton pump inhibitor‐therapy is considered an effective therapy for FD, but no other treatment approach reached consensus support.
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- 2021
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19. Identifying Entrustable Professional Activities for Shared Decision Making in Postgraduate Medical Education: A National Delphi Study
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Baghus, Anouk, Giroldi, Esther, Muris, Jean, Stiggelbout, Anne, van de Pol, Marjolein, Timmerman, Angelique, and van der Weijden, Trudy
- Abstract
Supplemental Digital Content is available in the text.
- Published
- 2021
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20. Time to diagnosis of symptomatic gastric and oesophageal cancer in the Netherlands: Where is the room for improvement?
- Author
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van Erp, NF, Helsper, CW, Slottje, P, Brandenbarg, D, Büchner, FL, van Asselt, KM, Muris, JWM, Kortekaas, MF, Peeters, PHM, and de Wit, NJ
- Abstract
Background An efficient diagnostic pathway and early stage diagnosis for cancer patients is widely pursued. This study aims to chart the duration of the diagnostic pathway for patients with symptomatic oesophageal and gastric cancer, to identify factors associated with long duration and to assess the association of duration with tumour stage at diagnosis.Methods This was a retrospective cohort study, using electronic health records of six routine primary care databases covering about 640,000 patients, partly linked to the Netherlands Cancer Registry. Symptomatic patients with oesophageal and gastric cancer (2010–2015) that presented in primary care were included. Duration of four diagnostic intervals was determined: patient interval; first symptoms to primary care consultation, primary care interval; consultation to referral, secondary care interval; referral to diagnosis, and the diagnostic interval; consultation to diagnosis. Characteristics associated with ‘long duration’ (≥P75 duration) were assessed using log-binomial regression. Median durations were stratified for tumour stages.Results Among 312 symptomatic patients with upper gastrointestinal cancer, median durations were: patient interval: 29 days (interquartile interval 15–73), primary care interval: 12 days (interquartile interval 1–43), secondary care interval: 13 days (interquartile interval 6–29) and diagnostic interval: 31 days (11–74). Patient interval duration was comparable for patients with and without alarm symptoms. Absence of cancer-specific alarm symptoms was associated with ‘long duration’ of primary care interval and secondary care interval: relative risk 5.0 (95% confidence interval 2.7–9.1) and 2.1 (95% confidence interval 1.3–3.7), respectively. Median diagnostic interval duration for local stage disease was 51 days (interquartile interval 13–135) versus 27 days (interquartile interval 11–71) for advanced stage (p= 0.07).Conclusion In the diagnostic pathway of upper gastrointestinal cancers, the longest interval is the patient interval. Reducing time to diagnosis may be achieved by improving patients’ awareness of alarm symptoms and by diagnostic strategies which better identify cancer patients despite low suspicion.
- Published
- 2020
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21. Time to diagnosis of symptomatic gastric and oesophageal cancer in the Netherlands: Where is the room for improvement?
- Author
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Erp, NF, Helsper, CW, Slottje, P, Brandenbarg, D, Büchner, FL, Asselt, KM, Muris, JWM, Kortekaas, MF, Peeters, PHM, and Wit, NJ
- Abstract
An efficient diagnostic pathway and early stage diagnosis for cancer patients is widely pursued. This study aims to chart the duration of the diagnostic pathway for patients with symptomatic oesophageal and gastric cancer, to identify factors associated with long duration and to assess the association of duration with tumour stage at diagnosis. This was a retrospective cohort study, using electronic health records of six routine primary care databases covering about 640,000 patients, partly linked to the Netherlands Cancer Registry. Symptomatic patients with oesophageal and gastric cancer (2010–2015) that presented in primary care were included. Duration of four diagnostic intervals was determined: patient interval; first symptoms to primary care consultation, primary care interval; consultation to referral, secondary care interval; referral to diagnosis, and the diagnostic interval; consultation to diagnosis. Characteristics associated with ‘long duration’ (=P75 duration) were assessed using log-binomial regression. Median durations were stratified for tumour stages. Among 312 symptomatic patients with upper gastrointestinal cancer, median durations were: patient interval: 29 days (interquartile interval 15–73), primary care interval: 12 days (interquartile interval 1–43), secondary care interval: 13 days (interquartile interval 6–29) and diagnostic interval: 31 days (11–74). Patient interval duration was comparable for patients with and without alarm symptoms. Absence of cancer-specific alarm symptoms was associated with ‘long duration’ of primary care interval and secondary care interval: relative risk 5.0 (95% confidence interval 2.7–9.1) and 2.1 (95% confidence interval 1.3–3.7), respectively. Median diagnostic interval duration for local stage disease was 51 days (interquartile interval 13–135) versus 27 days (interquartile interval 11–71) for advanced stage (p?=?0.07). In the diagnostic pathway of upper gastrointestinal cancers, the longest interval is the patient interval. Reducing time to diagnosis may be achieved by improving patients’ awareness of alarm symptoms and by diagnostic strategies which better identify cancer patients despite low suspicion.
- Published
- 2020
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22. Asymmetric causality between oil price and stock returns:A sectoral analysis.
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Bahmani-Oskooee, Mohsen, Ghodsi, Seyed Hesam, and Hadzic, Muris
- Subjects
PETROLEUM sales & prices ,STOCK prices ,STOCK price indexes - Abstract
The majority of past studies assessed the impact of oil price on stock returns using aggregate stock price index from different countries and assuming the effects to be symmetric. In this paper, we investigate asymmetric causality not only from oil price to stock returns but also from stock returns to oil price. To reduce aggregation bias, we use data from nine different sectors of the U.S. economy. We found that an increase in oil price causes returns of three sectors, while a decrease in oil price causes returns of four sectors, all in the short run. On the other hand, we found that an increase in returns in three sectors causes oil price to rise, while a decrease in returns in six sectors causes oil price to decline. We do not discover significant long-run causal relationship in either direction. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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23. Effects of Costus speciosus ethanolic extract on male rats: The action mechanism and the ability to impregnate.
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Sari, Ika Puspita, Nurrochmad, Arief, Setiawan, Irfan Muris, Hertiani, Triana, Paramita, Annisa Dian, and Annisa, Anggit Yustitia
- Abstract
To examine the action mechanism that mediates the anti-fertility effect of Costus speciosus extract, research was conducted on male Sprague-Dawley rats. Costus extract was given to male rats for 14 days at various doses, namely 275, 550 and 1,100 mg kg
-1 day-1 in 0.5% sodium CMC. The results showed that Costus extract with doses ranging from 275 to 1,100 mg kg-1 day-1 was able to inhibit pregnancy among female rats by 10-70%. No obstacles in terms of sexual behavior were identified among male rats. The anti-fertility effect of Costus extract kicked in without involving a decreased level of male reproductive hormones. [ABSTRACT FROM AUTHOR]- Published
- 2018
24. MODEL ELITE WORLD JUNIOR HANDBALL GOALKEEPER WITH VISUALIZATION.
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Bajgorić, Sanja, Đug, Muris, and Bijedić, Nina
- Subjects
DECISION making ,BODY mass index ,MATHEMATICAL models ,REGRESSION analysis - Abstract
The aim of this research is to construct the model of an elite world junior handball goalkeeper, based on the information from the official statistics run by the EHF at the 2013 World Junior Championship in Bosnia and Herzegovina. In total, 42 elite world junior goalkeepers were analysed. The model of the elite world junior handball player was constructed on the basis of a set of 28 variables: The basic central and dispersion parameters, factor, discriminatory and regression analysis were calculated for all examined variables. To determine the model goalkeeper, the average values of ten goalkeepers were taken by each of the selected defence elements, which resulted in average results of the best and at the same time reduced variability was achieved. On the basis of the results, a model of the elite world junior goalkeeper was constructed, who should, on average, be 189 cm high, weigh 88.56 kg and have a BMI of 24.71. The goalkeeper, as a model, should have 48% to 52.78% of defences from the field. From the line, this number shouldbe 32.00% to 50.41%, while from the wing he should have from 28.69% to 46.18% defence. From the passage, he should have a percentage of defence from 29.87% to 48.01%, while the high-speed centre should have a percentage of defence from 34.07% to 53.20%. From the seven meterline he should have from 36.42% to 46.56% defence percentage. Total should be from 44.71% to 53.20% of defence per game. [ABSTRACT FROM AUTHOR]
- Published
- 2017
25. Asymmetric causality between oil price and stock returns:A sectoral analysis
- Author
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Bahmani-Oskooee, Mohsen, Ghodsi, Seyed Hesam, and Hadzic, Muris
- Abstract
The majority of past studies assessed the impact of oil price on stock returns using aggregate stock price index from different countries and assuming the effects to be symmetric. In this paper, we investigate asymmetric causality not only from oil price to stock returns but also from stock returns to oil price. To reduce aggregation bias, we use data from nine different sectors of the U.S. economy. We found that an increase in oil price causes returns of three sectors, while a decrease in oil price causes returns of four sectors, all in the short run. On the other hand, we found that an increase in returns in three sectors causes oil price to rise, while a decrease in returns in six sectors causes oil price to decline. We do not discover significant long-run causal relationship in either direction.
- Published
- 2019
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26. Dealing With False Memories in Children and Adults: Recommendations for the Legal Arena
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Otgaar, Henry, Howe, Mark L., Muris, Peter, and Merckelbach, Harald
- Abstract
Children are often viewed as poor eyewitnesses. Fact-finders, lawyers, and researchers assume that children are exceptionally prone to accept external suggestive (leading) questions and to create false memories. Is this assumption justified? This review will show it is not. First, studies on spontaneous false memories—elicited without any suggestive pressure—reveal that children are less likely than adults to produce them. Second, under certain circumstances, children are even less prone to accept external suggestions than adults. This counterintuitive finding happens when false suggestions contain information that is associatively related but in actuality not experienced by children or adults. Using empirically based interview protocols can maximize the retrieval of accurate memories in children and adults. Furthermore, expert witnesses should use alternative scenarios to better evaluate whether statements by children or adults are based on truth or fiction.
- Published
- 2019
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27. Associative Activation as a Mechanism Underlying False Memory Formation
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Otgaar, Henry, Howe, Mark L., Muris, Peter, and Merckelbach, Harald
- Abstract
We recently made the case that associative activation is a viable mechanism underlying false memory formation and hence also false memory formation in psychopathology. In a recent issue of Clinical Psychological Science, Tryon argued that our description of associative activation did not meet the criteria of causation and explanatory value in order to qualify as a mechanism. In this commentary, we explain why we disagree with Tryon. Many studies focused on associative activation and false memory creation. We believe that these studies provide good arguments for associative activation as a likely causal antecedent in the production of false memories.
- Published
- 2019
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28. Fully Decentralized Approximate Zero-Forcing Precoding for Massive MIMO Systems
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Sarajlic, Muris, Rusek, Fredrik, Rodriguez Sanchez, Jesus, Liu, Liang, and Edfors, Ove
- Abstract
We analyze the downlink of a massive multiuser multiple input, multiple output (MIMO) system where antenna units at the base station are connected in a daisy chain without a central processing unit and only possess local channel knowledge. For this setup, we develop and analyze a linear precoding algorithm for suppressing interuser interference. It is demonstrated that the algorithm is close to zero-forcing precoding in terms of performance for a large number of antennas. Moreover, we show that with careful scheduling of processing across antennas, requirements for interconnection throughput are reduced compared with the fully centralized solution. Favorable tradeoff between performance and interconnection throughput makes the daisy chain a viable candidate topology for real-life implementations of base stations in MIMO systems where the number of antennas is very large.
- Published
- 2019
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29. What Drives False Memories in Psychopathology? A Case for Associative Activation
- Author
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Otgaar, Henry, Muris, Peter, Howe, Mark L., and Merckelbach, Harald
- Abstract
In clinical and court settings, it is imperative to know whether posttraumatic stress disorder (PTSD) and depression may make people susceptible to false memories. We conducted a review of the literature on false memory effects in participants with PTSD, a history of trauma, or depression. When emotional associative material was presented to these groups, their levels of false memory were raised relative to those in relevant comparison groups. This difference did not consistently emerge when neutral or nonassociative material was presented. Our conclusion is supported by a quantitative comparison of effect sizes between studies using emotional associative or neutral, nonassociative material. Our review suggests that individuals with PTSD, a history of trauma, or depression are at risk for producing false memories when they are exposed to information that is related to their knowledge base.
- Published
- 2017
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30. Do climate variations explain bilateral migration? A gravity model analysis.
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Backhaus, Andreas, Martinez-Zarzoso, Inmaculada, and Muris, Chris
- Published
- 2015
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31. ‘ Trouver une langue ’: Rimbaud et l’éthique de la traduction
- Author
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Muris-Prime, Camille
- Abstract
Dans les lettres dites « du voyant », Rimbaud se donne comme tâche de « trouver une langue » engageant une réflexion sur ce qu'est la langue de création qui s'accompagne dans sa poésie d'une interrogation sur la qualité du matériau poétique qu'est le langage et sur sa forme: celle de la prose. Trouver une langue pour faire de la poésie c'est trouver la forme d'une parole polyphonique et presque polyglotte. Le « je est un autre » de Rimbaud résonne avec la formule de Derrida « Je n'ai qu'une langue mais ce n'est pas la mienne » pour la transformer en: « Je n'est qu'une langue, mais ce n'est pas moi. » La poésie rimbaldienne se définit comme un projet où le je est à la fois multiple et potentiel pour devenir ce « lieu mixte » dont parle Kristin Ross et mettre au point ce que nous appellerons une éthique de la traduction.
- Published
- 2017
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32. Activity Levels and Exercise Motivation in Patients With COPD and Their Resident Loved Ones
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Mesquita, Rafael, Nakken, Nienke, Janssen, Daisy J.A., van den Bogaart, Esther H.A., Delbressine, Jeannet M.L., Essers, Johannes M.N., Meijer, Kenneth, van Vliet, Monique, de Vries, Geeuwke J., Muris, Jean W.M., Pitta, Fabio, Wouters, Emiel F.M., and Spruit, Martijn A.
- Abstract
Resident loved ones of patients with COPD can play an important role in helping these patients engage in physical activity. We aimed to compare activity levels and exercise motivation between patients with COPD and their resident loved ones; to compare the same outcome measures in patients after stratification for the physical activity level of the loved ones; and to predict the likelihood of being physically active in patients with a physically active resident loved one.
- Published
- 2017
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33. BRCA1-like signature in triple negative breast cancer: Molecular and clinical characterization reveals subgroups with therapeutic potential.
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Severson, Tesa M., Peeters, Justine, Majewski, Ian, Michaut, Magali, Bosma, Astrid, Schouten, Philip C., Chin, Suet-Feung, Pereira, Bernard, Goldgraben, Mae A., Bismeijer, Tycho, Kluin, Roelof J.C., Muris, Jettie J.F., Jirström, Karin, Kerkhoven, Ron M., Wessels, Lodewyk, Caldas, Carlos, Bernards, René, Simon, Iris M., and Linn, Sabine
- Abstract
Triple negative (TN) breast cancers make up some 15% of all breast cancers. Approximately 10–15% are mutant for the tumor suppressor, BRCA1. BRCA1 is required for homologous recombination-mediated DNA repair and deficiency results in genomic instability. BRCA1 -mutated tumors have a specific pattern of genomic copy number aberrations that can be used to classify tumors as BRCA1 -like or non- BRCA1 -like. BRCA1 mutation, promoter methylation, BRCA1 -like status and genome-wide expression data was determined for 112 TN breast cancer samples with long-term follow-up. Mutation status for 21 known DNA repair genes and PIK3CA was assessed. Gene expression and mutation frequency in BRCA1 -like and non- BRCA1 -like tumors were compared. Multivariate survival analysis was performed using the Cox proportional hazards model. BRCA1 germline mutation was identified in 10% of patients and 15% of tumors were BRCA1 promoter methylated. Fifty-five percent of tumors classified as BRCA1 -like. The functions of genes significantly up-regulated in BRCA1 -like tumors included cell cycle and DNA recombination and repair. TP53 was found to be frequently mutated in BRCA1 -like ( P < 0.05), while PIK3CA was frequently mutated in non- BRCA1 -like tumors ( P < 0.05). A significant association with worse prognosis was evident for patients with BRCA1 -like tumors (adjusted HR = 3.32, 95% CI = 1.30–8.48, P = 0.01). TN tumors can be further divided into two major subgroups, BRCA1 -like and non- BRCA1 -like with different mutation and expression patterns and prognoses. Based on these molecular patterns, subgroups may be more sensitive to specific targeted agents such as PI3K or PARP inhibitors. [ABSTRACT FROM AUTHOR]
- Published
- 2015
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34. CHAPTER 8: The FTC and Market Manipulation in Wholesale Petroleum Markets.
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Muris, Timothy J. and Kane, Maryanne S.
- Subjects
PETROLEUM law & legislation ,MARKET manipulation ,PETROLEUM ,WHOLESALE trade ,MARKETING ,LAW - Abstract
The article focuses on the development of the regulations imposed by the U.S. Federal Trade Commission (FTC) to prevent market manipulation in the petroleum industry. It explains that to avoid fraud, FTC issued a Final Rule which would illegalize any practice related to the sale of covered products at wholesale. It also concludes that due to the lack of manipulation in the market, the FTC devised the Final Rule to focus on fraud and not on regulating the operational decisions of the industry.
- Published
- 2010
35. Integrate Process Cluster.
- Author
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Koop, Reinder and Muris, Esther
- Published
- 2007
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36. Customize Process Cluster.
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Koop, Reinder and Muris, Esther
- Published
- 2007
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37. Map Process Cluster.
- Author
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Koop, Reinder and Muris, Esther
- Published
- 2007
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38. Model Process Cluster.
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Koop, Reinder and Muris, Esther
- Published
- 2007
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39. The Regatta for Dynamics Model.
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Koop, Reinder and Muris, Esther
- Published
- 2007
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40. Implementing Microsoft Dynamics.
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Koop, Reinder and Muris, Esther
- Published
- 2007
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41. Le compartiment microbien des sols soumis à l’infiltration des eaux pluviales urbaines. Description et rôle dans le transfert des metaux
- Author
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Delolme, Cécile, Bedell, Jean-Philippe, Winiarski, Thierry, Larmet, Hélène, Neto, Manuelle, Muris, Myriam, Perrodin, Yves, Delolme, Cécile, Bedell, Jean-Philippe, Winiarski, Thierry, Larmet, Hélène, Neto, Manuelle, Muris, Myriam, and Perrodin, Yves
- Abstract
L’infiltration des eaux pluviales urbaines dans les nappes est une technique alternative au système traditionnel d’assainissement largement utilisée dans l’Est lyonnais. Les eaux infiltrées conduisent à l’accumulation dans les premiers centimètres du sol de matière organique, de polluants organiques et minéraux et de micro-organismes. Ce papier présente les différents travaux menés pour mieux comprendre le rôle du compartiment microbien de cette surface sur le devenir des métaux piégés à la surface et le risque de leur migration dans la nappe souterraine. Une approche sur métal et bactérie modèles a permis de mettre en évidence une forte capacité d’adsorption des cations métalliques par la bactérie, adsorption qui peut conduire au transfert de ce métal via le transport biocolloïdal. Des études sur milieu réels multicontaminés montre que les bactéries présentes en grands nombres dans ces milieux pollués sont adaptées à ce stress chimique et sont potentiellement très actives.
- Published
- 2005
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42. Physical Activity Is Associated With Glucose Tolerance Independent of Microvascular Function: The Maastricht Study
- Author
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Montero, David, Houben, Alfons J. H. M., Koster, Annemarie, Muris, Dennis M. J., Schram, Miranda T., Gronenschild, Ed H., Sep, Simone J. S., Henry, Ronald M. A., van der Kallen, Carla J. H., Schaper, Nicolaas C., Dagnelie, Pieter C., van Geel, Tineke A. C. M., Kremers, Stef P. J., Savelberg, Hans H. C. M., and Stehouwer, Coen D. A.
- Abstract
Context and Objective:Moderate-to-vigorous physical activity (MVPA) and physical fitness (PF) are positively associated with glucose tolerance. Such associations may be partly conditioned by microvascular function, which is a common correlate to MVPA, PF, and glucose tolerance. To test this hypothesis, the present study sought to investigate independent associations of MVPA and PF with glucose tolerance and to what extent these associations are mediated by microvascular function.Design, Setting, Participants, and Outcome Measures:Data from The Maastricht Study were used (n = 512 for MVPA and n = 488 for PF analyses; mean age, 59 [SD = 9] y, 52 % men). Glucose tolerance was assessed by 2-hour postload plasma glucose levels (2hPG). The total number of weekly hours of MVPA was estimated with the Community Healthy Activities Model Program for Seniors questionnaire. Walking speed during the 6-minute walk test was used to evaluate PF. Microvascular function was determined by postocclusive capillary recruitment and flowmotion with capillaroscopy and laser Doppler flowmetry in skin microcirculation.Results:In univariate analyses, MVPA, PF, and microvascular function variables were associated with 2hPG. MVPA (n = 512, β = −0.056, P= .019) and PF (n = 488, β = −0.368, P= .006) remained associated with 2hPG after adjustment for established cardio-metabolic risk factors and history of cardiovascular disease; addition of microvascular function variables as potential mediators did not materially change the associations of MVPA (β = −0.054, P= .024) and PF (β = −0.364, P= .006) with 2hPG. No mediation effects of microvascular function variables were detected.Conclusions:MVPA and PF were independently associated with 2hPG, irrespective of established risk factors and generalized microvascular function. The possibility that specific microvascular functions, eg, insulin-mediated vasodilation, influence the association of MVPA and PF with 2hPG needs further investigation.
- Published
- 2016
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43. Development of Nanozeolite-Geopolymer as Adsorbent Material for Motor Vehicle Emissions
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Saludung, Apriany, Wardani, Nurul Kusuma, Subaer, and Muris
- Abstract
This study examines the ability of nanozeolite-geopolyme ras adsorbent material for motor vehicle emissions. There were three samples that have been synthesized by varying metakaolin and rice husk ash masses. Nanozeolite-geopolymer samples were synthesized through geopolymerization method at 70°C by mixing metakaolin with rice husk ash and activated with NaOH solution. Samples were recurring at 200°C to improve the crystalline level. Based on the XRD characterization of the three samples, two of them contain zeolite X, namely ZG_A (100% metakaolin, ASP 0%) and ZG_B (metakaolin: ASP, 2: 1). However, zeolite X phase most conceived by ZG_A. Therefore, the ZG_A sample was then used as adsorbent to absorb motor vehicle exhaust. The tests were performed four times with time variation of 10, 20, 30, and 40 minutes. The XRD results showed that the material was successfully absorbed lead oxide, manganese oxide and phosphorus which are hazardous compounds when inhale by human being.
- Published
- 2016
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44. Do climate variations explain bilateral migration? A gravity model analysis
- Author
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Backhaus, Andreas, Martinez-Zarzoso, Inmaculada, and Muris, Chris
- Abstract
This paper investigates to what extent international migration can be explained by climatic variations. A gravity model of migration augmented with average temperature and precipitation in the country of origin is estimated using a panel data set of 142 sending countries for the period 1995 to 2006. We find two primary results. First, temperature is positively correlated with migration. Second, stronger changes in precipitation are also associated with aligned, but small changes in migration. Both effects are robust to various model modifications. Furthermore, we present initial explorations into the channels relating climate changes with migration via agriculture and internal conflict. F22, Q54
- Published
- 2015
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45. Old friends, new story: The role of Slit2C signaling through PlexinA1
- Author
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Schiweck, Juliane, Beauchamp, Marta, Humo, Muris, and Lelievre, Vincent
- Abstract
Growth cone guidance is driven by attractive and repulsive signaling cues. Until recently, repulsive signaling by semaphorins was thought to be mediated through Plexin receptors, whereas Slits-induced repulsion was solely mediated through Robo receptors. In a recent report published in Nature Neuroscience, Celine Delloye-Bourgeois and colleagues (2015) combined phenotypic analyses of transgenic mouse lines and in vitrobiochemical experiments to identify PlexinA1 as a novel receptor for Slits. Strikingly, they uncovered for the very first time that the Slit2C-terminal fragment possesses some unique biological activity as binding partner for PlexinA1. Even more excitingly, the signaling cascade triggered by SlitC binding to PlexinA1 mediates growth cone collapse of commissural axons both in vivoand ex vivoand nicely complements Robo-Slit signaling in the developing spinal cord midline to prevent midline recrossing.
- Published
- 2015
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46. Electronic monitoring of symptoms and lung function to assess asthma control in children.
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van Vliet, Dillys, van Horck, Marieke, van de Kant, Kim, Vaassen, Sanne, Gulikers, Sjoerd, Winkens, Bjorn, Rosias, Philippe, Heynens, Jan, Muris, Jean, Essers, Brigitte, Jöbsis, Quirijn, and Dompeling, Edward
- Published
- 2014
- Full Text
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47. Beta lactam antibiotics residues in cow's milk: comparison of efficacy of three screening tests used in Bosnia and Herzegovina.
- Author
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Fejzić, Nihad, Begagić, Muris, Šerić-Haračić, Sabina, and Smajlović, Muhamed
- Published
- 2014
- Full Text
- View/download PDF
48. Desire for social interaction in children with autism spectrum disorders.
- Author
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Deckers, Anne, Roelofs, Jeffrey, Muris, Peter, and Rinck, Mike
- Abstract
Highlights: [•] Desire for social interaction in ASD is a clinically relevant but understudied subject. [•] Desire for social interaction can be assessed on an explicit and implicit level. [•] Children with ASD showed a decreased explicit desire for social interaction. [•] Children with ASD showed an increased implicit approach tendency towards social as well as non-social stimuli. [Copyright &y& Elsevier]
- Published
- 2014
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49. Prognostic value of neutrophil-to-lymphocyte ratio (NLR) in penile cancer: A systematic review and meta-analysis
- Author
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Saputra, Haviv Muris, Hidayatullah, Furqan, Kloping, Yudhistira Pradnyan, Renaldo, Johan, Chung, Eric, and Hakim, Lukman
- Abstract
Penile cancer is rare among male malignancies. Various biomarkers have been used to predict the prognosis of cancer, one of which is the neutrophil to lymphocyte ratio (NLR). Therefore, we conducted this systematic review and meta-analysis to evaluate the prognostic value of NLR in penile cancer.
- Published
- 2022
- Full Text
- View/download PDF
50. Uric acid and skin microvascular function: the Maastricht study
- Author
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Wijnands, José M.A., Houben, Alfons J.H.M., Muris, Dennis M.J., Boonen, Annelies, Schram, Miranda T., Sep, Simone J.S., van der Kallen, Carla J.H., Henry, Ronald M.A., Dagnelie, Pieter C., van der Linden, Sjef, Schaper, Nicolaas C., Arts, Ilja C.W., and Stehouwer, Coen D.A.
- Abstract
Supplemental Digital Content is available in the text
- Published
- 2015
- Full Text
- View/download PDF
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