Author: "Mingoia, F" / Database: Supplemental Index - Searchworks@Jio Institute Digital Library Search Results

Author: Almerico, A. M., Mingoia, F., Diana, P., Barraja, P., Lauria, A., Montalbano, A., Cirrincione, G., and Dattolo, G.
Abstract: 1-Methylpyrazolo[1,2-a]benzo[1,2,3,4]tetrazin-3-ones 4, synthesized in good to excellent yields, were designed as novel alkylating agents because of their peculiar chemical behavior. All derivatives showed antiproliferative activity against more than 50 types of tumor cell lines with GI50 reaching sub-micromolar values. SAR studies revealed that the presence of a chlorine atom is well-tolerated in both positions 8 and 9, whereas in the case of the methyl group, switching from the 8 to the 9 position gives rise to the most active compound of the series, 4g, either for the number of cell lines inhibited and for selectivity against leukaemia and renal cancer subpanels. COMPARE and 3D-MIND computations indicate, for compounds 4, an activity profile analogous to rifamycins and cytidine analogues.
Published: 2005

Author: Aiello, E., Aiello, S., Mingoia, F., Bacchi, A., Pelizzi, G., Musiu, C., Setzu, M. Giovanna, Pani, A., Colla, P. La, and Marongiu, M. Elena
Published: 2000
Full Text: View/download PDF

Author: Preobrazhenskaya, M.N., Korolev, A.M., Rozhkov, I.I., Yudina, L.N., Lazhko, E.I., Aiello, E., Almerico, A.M., and Mingoia, F.
Published: 1999
Full Text: View/download PDF

Author: Cirrincione, G., Almerico, A. M., Passannanti, A., Diana, P., and Mingoia, F.
Published: 1997
Full Text: View/download PDF

Author: ALMERICO, A. M., BARRAJA, P., DIANA, P., CIRRINCIONE, G., MINGOIA, F., MUSIU, C., PERRA, G., PUTZOLU, M., and MARONGIU, M. E.
Abstract: ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Published: 1998
Full Text: View/download PDF

Author: ALMERICO, A. M., DIANA, P., BARRAJA, P., DATTOLO, G., MINGOIA, F., LOI, A. G., SCINTU, F., MILIA, C., PUDDU, I., and LA COLLA, P.
Abstract: ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Published: 1998
Full Text: View/download PDF

Author: PASSANNANTI, A., DIANA, P., BARRAJA, P., MINGOIA, F., LAURIA, A., and CIRRINCIONE, G.
Abstract: ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Published: 1998
Full Text: View/download PDF

Author: DIANA, P., BARRAJA, P., ALMERICO, A. M., DATTOLO, G., MINGOIA, F., LOI, A. G., CONGEDDU, E., MUSIU, C., PUTZOLU, M., and LA COLLA, P.
Abstract: ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Published: 1997
Full Text: View/download PDF

Searchworks