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It is argued that memory for traumatic events is similar to that for other distinctive, personally significant events regardless of whether they are affectively positive or negative. Examined in this light, the focus now shifts to the role of individual differences in neurobiological, social, cognitive, and constitutional factors that conspire to determine long-term retention of significant autobiographical experiences. What is known about these factors in determining memorability is reviewed, issues of measurement inadequacies discussed, and recommendations for further research outlined.