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1. Evaluation of antitumoral effect of Hibiscus sabdariffa extract on human breast cancer cells

Author

Malacrida, Alessio, Erriquez, Jacopo, Hashemi, Maryamsadat, Rodriguez-Menendez, Virginia, Cassetti, Arianna, Cavaletti, Guido, and Miloso, Mariarosaria

Abstract

BackgroundBreast cancer is the most frequent tumor in women. Natural substances represent an important source of innovative therapeutic solutions, eventually integrating or substituting conventional drugs and chemicals. Hibiscus sabdariffa L. is a plant of the Malvaceae family that has raised interest thanks to its anti-inflammatory, antioxidant and anticancer effects. In this work, we evaluated the antitumoral effects of an enriched fraction of Hibiscus sabdariffa L. extract (HsEF) in two human breast cancer cell lines, MCF-7(ERα +) and MDA-MB-231 (triple negative).

Published
2022
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