1,263 results on '"MING LI"'
Search Results
2. DERIVING COLLECTIVE RECOMMENDATION WITH ASPECT-BASED SENTIMENT AND SOCIAL INFLUENCE.
- Author
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Jyh-Hwa Liou, Ssu-Yu Chen, Yung-Ming Li, and Guangming Cao
- Abstract
Despite the vast amount of restaurant information shared on social platforms, users often face difficulties identifying suitable options efficiently. Ratings are constrained by information narrowness, while textual reviews pose challenges due to information overload. Furthermore, restaurant recommendations based solely on ratings lack objectivity, as individual preferences differ. Users cannot judge whether a restaurant is worth visiting without credible information. However, few existing studies integrate semantic analysis with multidimensional orientation and social influence to make recommendations, leaving a gap in objective and comprehensive analysis. This research proposes a synthesis collective recommendation approach utilizing machine learning with aspect-based sentiment and social influence analyses. The proposed approach can appropriately adjust ratings as a basis for deciding the list of recommendations, considering location and preference factors. Experimental results show that the proposed mechanism significantly enhances users' ability to find restaurants that meet their needs, thereby improving business opportunities. [ABSTRACT FROM AUTHOR]
- Published
- 2024
3. Subventricular zone--associated classification in isocitrate dehydrogenase--wildtype glioblastomas: improved prognostic value through integration of FLAIR with contrast-enhanced imaging.
- Author
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Xuzhe Zhao, Xiaohui Ren, Mingxiao Li, Haihui Jiang, Ming Li, Haibin Wan, Yutao Zhang, Song Lin, and Dabiao Zhou
- Published
- 2024
- Full Text
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4. Identification of male sterility-related genes in Saccharum officinarumand Saccharum spontaneum
- Author
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Song, Jinjin, Zhang, Xiaodan, Jones, Tyler, Wang, Ming-Li, and Ming, Ray
- Abstract
Key message: Candidate male sterility genes were identified in sugarcane, which interacts with kinase-related proteins, transcription factors, and plant hormone signaling pathways to regulate stamen and anther development. Abstract: Saccharum officinarumis a cultivated sugarcane species that its predominant feature is high sucrose content in stems. Flowering is necessary for breeding new cultivars but will terminate plant growth and reduce sugar yield. The wild sugarcane species Saccharum spontaneumhas robust and viable pollen, whereas most S. officinarumaccessions are male sterile, which is a desirable trait of a maternal parent in sugarcane breeding. To study male sterility and related regulatory pathways in sugarcane, we carried out RNAseq using flowers in different developmental stages between male-sterile S. officinarumaccession ‘LA Purple’ and fertile S. spontaneumaccession ‘SES208’. Gene expression profiles were used to detect how genes are differentially expressed between male sterile and fertile flowers and to identify candidate genes for male sterility. Weighted gene correlation networks analysis (WGCNA) was conducted to investigate the regulatory networks. Transcriptomic analyses showed that 988 genes and 2888 alleles were differentially expressed in S. officinarumcompared to S. spontaneum. Ten differentially expressed genes and thirty alleles were identified as candidate genes and alleles for male sterility in sugarcane. The gene Sspon.03G0007630and two alleles of the gene Sspon.08G0002270, Sspon.08G0002270-2Band Sspon.08G0014700-1A,were involved in the early stamen or carpel development stages, while the remaining genes were classified into the post-meiosis stage. Gibberellin, auxin, and jasmonic acid signaling pathways are involved in the stamen development in sugarcane. The results expanded our knowledge of male sterility-related genes in sugarcane and generated genomic resources to facilitate the selection of ideal maternal parents to improve breeding efficiency.
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- 2024
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5. Inertial and Deterministic Lateral Displacement Integrated Microfluidic Chips for Epithelial–Mesenchymal Transition Analysis
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Zhao, Ya-Nan, Zhang, Xuan, Bai, Jun-Jie, Jia, Hao-Yu, Chen, Ming-Li, and Wang, Jian-Hua
- Abstract
With the aim of efficiently sorting rare circulating tumor cells (CTCs) from blood and minimizing damage to CTCs during isolation, we constructed an inertia-assisted single-cell focusing generator (I-SCF) and a water droplet deterministic lateral displacement cell sorting (D-DLD) microfluidic system (IDIC) based on different sizes, the device is initially sorted by a continuous fluid swing and Dean flow-assisted helical micromixers, then flows through a droplet shaped DLD region, enabling single-cell focused sequencing and precise separation, improving cell separation efficiency (>95%) and purity, while ensuring a high single cells survival rate of more than 98.6%. Subsequently, breast cancer cell lines were run through our chip, and then the downstream epithelial–mesenchymal transition (EMT) process induced by TGF-β was detected, and the levels of three proteins, EpCAM, PD-L1, and N-cadherin, were analyzed to establish the relationship between PD-L1 and the EMT process. Compared with other analytical techniques such as the filtration method, the enrichment method and immunoaffinity capture methods, this method not only ensures the separation efficiency and purity, but also ensures the cell activity, and avoids missing the different results caused by the heterogeneity of CTCs due to the isolation of high purity (84.01%). The device has a high throughput processing capacity (5 mL of diluted whole blood/∼2.8 h). By using the chip, we can more easily and conveniently predict tumor stage and carry out cancer prevention and treatment in advance, and it is expected to be further developed into a clinical liquid biopsy technology in the future.
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- 2024
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6. Comparing the oncologic outcomes of local tumor destruction vs. local tumor excision vs. partial nephrectomy in T1a solid renal masses: a population-based cohort study from the SEER database.
- Author
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Run-Qi Guo, Peng-Jin Zhao, Jie Sun, and Yuan-Ming Li
- Abstract
Background: There are few large-scale analyses comparing local tumor destruction (LTD) or local tumor enucleation/excision (LTE) relative to partial nephrectomy (PN) for patients with T1a renal masses in terms of cancer-specific survival (CSS) and overall survival (OS). The authors aimed to compare CSS and OS after LTD versus LTE versus PN. Materials and methods: Within the Surveillance, Epidemiology, and End Results (SEER) database (2000-2019), the authors identified patients with clinical T1a renal masses and histologically confirmed kidney cancer treated with LTD, LTE, or PN. After 1:1 ratio propensity score matching (PSM), comparisons between the groups were conducted. Kaplan-Meier analysis and log-rank tests were used to compare survival in the matched population. Results: In the overall cohort of 3717 LTD patients versus 1993 LTE patients versus 26 935 PN patients, 77.3% of LTD-treated patients and 74.4% of LTE-treated patients were over 60 years old, while only 50.3% of PN-treated patients were over 60 years old. PN was more strongly associated with CSS [hazard ratio ((HR) = 1.276, P< 0.001) and OS (HR=1.112, P< 0.001)] than was LTD, while PN was less strongly associated with CSS (HR= 1.040, P =0.230) and OS (HR= 0.888, P =0.002) than was LTE, not only in the PSM cohort but also in the subgroups of patients with a tumor size =3 cm and patients with a tumor size of 3.1-4 cm. Conclusions: In clinical T1a solid renal mass patients, LTD was associated with lower CSS and OS than LTE and PN, while LTE demonstrated noninferior CSS and superior OS to PN regardless of tumor size. [ABSTRACT FROM AUTHOR]
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- 2024
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7. Electrical Responsive Coating with a Multilayered TiO2-SnO2-RuO2 Heterostructure on Ti for Controlling Antibacterial Ability and Improving Osseointegration.
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Rui Zhou, Yifei Liu, Ming Li, Jianyun Cao, Jiahui Cheng, Daqing Wei, Baoqiang Li, Yaming Wang, Dechang Jia, Bailing Jiang, Valiev, Ruslan Z., and Yu Zhou
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- 2024
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8. Superior Barrier Performance of Poly(lactic acid) Films via Constructing Well-Defined Nanosized Crystals and Sandwich Structure.
- Author
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Ke-Yu Lan, Chun-Yan Liu, Ping-Ping Xu, De-Long Li, Jin Yu, Gan-Ji Zhong, Hua-Dong Huang, and Zhong-Ming Li
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- 2024
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9. An Intramolecular Rotor-Bridged Dimeric Cyanine Photothermal Transducer for Efficient Near-Infrared II Fluorescence Imaging-Guided Mitochondria-Targeted Phototherapy.
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Jin-Feng Yu, Jialian Li, and Ming Li
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- 2024
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10. Hierarchical Structural Evolution, Electrical and Mechanical Performance of Polypropylene Containing Intrinsic Elastomers under Stretching and Annealing for Cable Insulation Applications.
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Zhang, Yu-Ting, Hou, Shuai, Li, De-Long, Cao, Ya-Jie, Zhan, Yun-Peng, Jia, Lei, Fu, Ming-li, and Huang, Hua-Dong
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- 2024
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11. Optimizing Acute Static Stretching Protocols: Balancing Range of Motion and Strength Performance.
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Ming Li, Youngsuk Kim, and Sukwon Kim
- Subjects
SPORTS sciences ,SPORTS medicine ,GROUND reaction forces (Biomechanics) ,VERTICAL jump ,ATHLETIC ability ,HAMSTRING muscle injuries - Abstract
The article discusses the optimization of acute static stretching protocols to balance range of motion and strength performance in athletes. It highlights the importance of considering factors such as duration, intensity, and combining static stretching with dynamic activities to minimize negative impacts on athletic performance. Research findings suggest that a 60-second static stretch at 100% point of discomfort intensity, combined with dynamic exercises, can enhance range of motion for up to 30 minutes without adversely affecting performance. The study emphasizes the need for tailored stretching protocols to support athletes in achieving optimal results while minimizing potential drawbacks. [Extracted from the article]
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- 2024
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12. Hierarchical Structural Evolution, Electrical and Mechanical Performance of Polypropylene Containing Intrinsic Elastomers under Stretching and Annealing for Cable Insulation Applications
- Author
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Zhang, Yu-Ting, Hou, Shuai, Li, De-Long, Cao, Ya-Jie, Zhan, Yun-Peng, Jia, Lei, Fu, Ming-li, and Huang, Hua-Dong
- Abstract
Thermoplastic polypropylene (PP) insulated cables, an alternative to cross-linked polyethylene, offer superior insulation, high operating temperature, recyclability, cost-effectiveness, and a limitless cable length. However, challenges such as brittleness at low temperatures and limited flexibility at room temperature impede the application of PP in the field of cable insulation. To address these issues, in-reactor alloy technology seems to be a promising strategy, creating a multiphase system with intrinsic elastomer dispersion in a homopolypropylene matrix. Most of the research on PP-based multiphase systems focuses on enhancing mechanical properties by controlling microscopic structures. A comprehensive understanding of structural evolution during processing and its correlation with the electrical performance of PP thermoplastic insulation materials remains in its infancy. In this study, PP in-reactor alloys with intrinsic elastomers were utilized as model polymeric materials. A novel technology of “melting extrusion–hot stretching–thermal annealing” was employed to manipulate the elastomer phase morphology and crystalline structure. Severe interfacial mismatch during hot stretching initially compromised the mechanical and electrical properties. After thermal annealing, the mechanical and electrical properties were recovered, arising from the reduced rubber deformation and increased crystalline reorganization. The work presented here is expected to help our understanding of the dependence of electrical and mechanical properties on the microstructure of PP in-reactor alloys, providing a valuable reference for the structural design of cable insulation.
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- 2024
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13. Genotype, environment, and their interaction effects on peanut seed protein, oil, and fatty acid content variability.
- Author
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Wang, Ming Li, Tonnis, Brandon, Li, Xianran, Benke, Ryan, Huang, Edward, Tallury, Shyam, Puppala, Naveen, Peng, Ze, and Wang, Jianping
- Abstract
Products from peanut seeds are nutritious for human and/or animal consumption. Peanut seed nutritional quality is determined by the genotype (G) of cultivars or accessions, environmental conditions (E), and their interactions (G × E). To evaluate the effects of genotype, environment, and their interactions on seed nutritional quality, 52 peanut germplasm accessions, which vary in oil content and fatty acid composition, were planted at three locations (Citra, FL; Byron, GA; and Clovis, NM) for 2 years (2017 and 2018). The harvested seeds were analyzed for protein, oil, and fatty acid composition using an N analyzer, nuclear magnetic resonance, and gas chromatography, respectively. Significant effects of accession, FAD2 gene, where FAD is fatty acid desaturase, location, year, and their interactions on the investigated traits were evaluated. The average oil content from accessions grown in Florida (51.1%) or Georgia (50.7%) was significantly higher than those grown in New Mexico (45.8%), whereas the average protein content from accessions grown in Florida (23.2%) was significantly lower than those grown in New Mexico (25.4%) or Georgia (24.8%). This is expected as there is a negative correlation between oil and protein content. After genotyping and classification (A/A, A/W, and G/W) for the FAD2A/FAD2B genes, the nutritional quality variations were further evaluated at the levels of the specific haplotype of FAD2A/FAD2B and explicit environmental index. The average prediction accuracy of seed nutritional quality trait values from the prediction model demonstrated that predicting trait values in new environments is feasible. The results of this study provide insights into the seed nutritional analysis, germplasm evaluation, and peanut breeding, cultivation, and production to peanut breeders, curators, farmers, and product processors. Core Ideas: Genotype, environment, and their interactions affect peanut seed nutritional quality.The FAD2A/FAD2B gene (F) effect significantly alters seed fatty acid composition.Location (L) effect significantly changes seed oil and protein content.Photothermal time may be a good parameter for representing the growing location environmental conditions for data analysis.Recommendation was given to farmers and processors on how to cultivate the right peanut varieties and purchase the right seeds from specific regions. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
14. Nursing Workloads and Lower Urinary Tract Symptoms Among Chinese Female Nurses: The Mediating Role of Delayed Voiding Behaviors.
- Author
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Yongjuan Rao, Chen Wu, Dongjuan Xu, Yongjian Zhu, Junxiu Ma, Jing Mou, Jie Gao, Jieqiong Ren, Ming Li, and Kefang Wang
- Subjects
URINARY organs ,PERCEIVED Stress Scale ,SUBJECTIVE stress ,NURSES ,STRUCTURAL equation modeling - Abstract
Purpose: Lower urinary tract symptoms (LUTS) are a challenge to the healthy nursing workforce. Nurses confront various objective and subjective nursing workloads which contribute to their LUTS, but less is known about how nursing workloads influence their LUTS. This study is designed to test hypotheses that delayed voiding behaviors mediate the relationships between nursing workloads and LUTS in female nurses. Materials and Methods: This study analyzed the baseline data collected from an ongoing cohort study named Nurse Urinary Related Health Study in China. LUTS of nurses in 20 tertiary hospitals were assessed with the International Consultation on Incontinence Questionnaire? Female Lower Urinary Tract Symptoms. Objective nursing workloads including working environment, working hours, and working schedule were collected, and perceived stress, the proxy of the subjective nursing workload, was assessed with the Perceived Stress Scale. Delayed voiding behaviors were assessed with 3 questions adapted from the Taiwan Nurse Bladder Survey. Structural equation modeling was used to run the mediation model. Results: More than half (51%) of 13,191 female nurses had LUTS. Median age was 31 years (IQR 27-37). When delayed voiding behaviors served as a mediator, the direct effects of subjective nursing workload rather than objective nursing workloads on LUTS were significant. Conclusions: Nursing workloads influence nurses' LUTS via delayed voiding behaviors. Strategies tailored to delayed voiding behaviors should be developed, and these may work with stress-reducing strategies as the gatekeepers for nurses' bladder health. [ABSTRACT FROM AUTHOR]
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- 2024
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15. Acupuncture regulating microglial activation in Alzheimer's disease: Research progress in its neuroinflammation mechanism: 针刺调节小胶质细胞活化治疗阿尔茨...
- Author
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WEI, Yu-ting, SU, Ming-li, REN, De-lin, ZHANG, Xin, ZHU, Tian-tian, and YAN, Xing-ke
- Abstract
Microglia (MG) activation and its mediated neuroinflammation are closely related to the occurrence and deterioration of Alzheimer's disease (AD). Acupuncture is one of the effective approach for AD, which can relieve the symptoms and slow the deterioration of AD. Based on the role of MG activation and its induced pro-inflammatory and anti-inflammatory phenotypes in neuroinflammation, this paper reviews the related literature on the mechanism of acupuncture in regulating MG activation and relieving neuroinflammation in AD. It is found that acupuncture can inhibit abnormal MG activation by regulating the release of MG surface immune receptors and pro-inflammatory/ anti-inflammatory cytokines. It can also modulate the activity of signaling pathways associated with MG polarization, downregulate the expression of M1, and promote MG polarization towards the M2 phenotype. Additionally, it adjusts the imbalance between M1 and M2 phenotypes of MG, thereby relieving the neuroinflammatory pathological procession of and repairing the neuronal damage so as to achieve its therapeutic effect. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
16. Genotype, environment, and their interaction effects on peanut seed protein, oil, and fatty acid content variability
- Author
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Wang, Ming Li, Tonnis, Brandon, Li, Xianran, Benke, Ryan, Huang, Edward, Tallury, Shyam, Puppala, Naveen, Peng, Ze, and Wang, Jianping
- Abstract
Products from peanut seeds are nutritious for human and/or animal consumption. Peanut seed nutritional quality is determined by the genotype (G) of cultivars or accessions, environmental conditions (E), and their interactions (G × E). To evaluate the effects of genotype, environment, and their interactions on seed nutritional quality, 52 peanut germplasm accessions, which vary in oil content and fatty acid composition, were planted at three locations (Citra, FL; Byron, GA; and Clovis, NM) for 2 years (2017 and 2018). The harvested seeds were analyzed for protein, oil, and fatty acid composition using an N analyzer, nuclear magnetic resonance, and gas chromatography, respectively. Significant effects of accession, FAD2gene, where FAD is fatty acid desaturase, location, year, and their interactions on the investigated traits were evaluated. The average oil content from accessions grown in Florida (51.1%) or Georgia (50.7%) was significantly higher than those grown in New Mexico (45.8%), whereas the average protein content from accessions grown in Florida (23.2%) was significantly lower than those grown in New Mexico (25.4%) or Georgia (24.8%). This is expected as there is a negative correlation between oil and protein content. After genotyping and classification (A/A, A/W, and G/W) for the FAD2A/FAD2Bgenes, the nutritional quality variations were further evaluated at the levels of the specific haplotype of FAD2A/FAD2Band explicit environmental index. The average prediction accuracy of seed nutritional quality trait values from the prediction model demonstrated that predicting trait values in new environments is feasible. The results of this study provide insights into the seed nutritional analysis, germplasm evaluation, and peanut breeding, cultivation, and production to peanut breeders, curators, farmers, and product processors. Genotype, environment, and their interactions affect peanut seed nutritional quality.The FAD2A/FAD2Bgene (F) effect significantly alters seed fatty acid composition.Location (L) effect significantly changes seed oil and protein content.Photothermal time may be a good parameter for representing the growing location environmental conditions for data analysis.Recommendation was given to farmers and processors on how to cultivate the right peanut varieties and purchase the right seeds from specific regions.
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- 2024
- Full Text
- View/download PDF
17. Two anachoropterid fern rachises from the in situvolcanic ash of the Whetstone Horizon (Kladno Formation, Pennsylvanian), Radnice Basin, Czech Republic
- Author
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Zhou, Wei-Ming, Pšenička, Josef, Votočková Frojdová, Jana, Wang, Jun, Wan, Ming-Li, and Feng, Zhuo
- Abstract
Two partly anatomically preserved axes parallelly situated on a slab collected from an in situvolcanic ash bed called “Bělka” of the Whetstone Horizon, Kladno Formation (Pennsylvanian), Czech Republic, were studied in detail. Anatomically, both axes possess a C-shaped xylem strand with protoxylem tracheids situated on the convex side, demonstrating an inversicatenalean-type anachoropterid affiliation. They are further suggested to belong to one biological species, as they share a number of similar characteristics and common structures. Systematically, one of the two studied axes retains a primitive form of foliar anatomy with the oldest known anachoropterid plant (Anachoropterissp.) in having two rather short lateral arms compared to the long median region. Although lacking foliage information, both axes likely belong to the rachis part of Discosoropteris zlatkokvacekiiPšenička, Zhou, Boyce, Votočková Frojdová, Bek and Wang, a fern species that was recently established based on the same slab where the two studied axes were preserved. Such a combination may further indicate the presence of a new family in the late Paleozoic anachoropterid plants. In addition, selected anatomically preserved ferns from the Whetstone Horizon were reviewed, which promotes a better understanding of the anatomical variability of fern species.
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- 2024
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18. Segmental ureterectomy outcome of upper tract urothelial carcinoma in a high endemic area A Taiwan nationwide collaborative study.
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Shih-Gang Wang, Hao-Lun Luo, Hung-Jen Wang, Wen-Jeng Wu, Wei-Ming Li, Po-Hung Lin, See-Tong Pang, Shian-Shiang Wang, Jian-Ri Li, Han-Yu Weng, Ta-Yao Tai, Jen-Shu Tseng, Wun-Rong Lin, I-Hsuan Alan Chen, Jen-Tai Lin, Yuan-Hong Jiang, Yu-Khun Lee, Jen Kai Fang, Chao-Yuan Huang, and Wen-Hsin Tseng
- Abstract
Purpose: According to the National Comprehensive Cancer Network guidelines, segmental ureterectomy (SU) of upper tract urothelial carcinoma (UTUC) is a considerable option for selected mid- and distal ureteral urothelial carcinoma (UC). As a UTUC endemic area, Taiwan lacks treatment outcome analysis of SU. Materials and methods: This study retrospectively reviewed the treatment outcomes of SU for clinically localized UTUCs. Patients with biopsy or washing cytology-confirmed UTUCs who underwent open, laparoscopic, or robot-assisted management with curative intent were retrospectively reviewed for the eligibility of analysis. Cox regression was applied for univariable and multivariable analyses. Results: A total of 161 patients who underwent SU were reviewed and analyzed. The median follow-up period was 44.5 (interquartile range, 21.6-84.9) months. After SU, 56/161 (34.8%) patients were free of UTUCs after the follow-up, 25/161 (15.5%) patients had local recurrence, and 35/161 (21.7%) had lymph node or distant metastasis. Surgical margin involvement was a risk factor associated with worse cancer-specific survival. Higher bladder recurrence and local recurrence rates were observed with concurrent bladder UC. Lymphovascular invasion and previous radical nephroureterectomy (RNU) for UC were related to higher local recurrence rates. Patients with pathological T3/T4 stage and end-stage renal disease tended to have higher metastasis rates. For the management of local recurrence, 19 patients received salvage RNU and 25 patients had adjuvant chemotherapy. However, 26/161 (16.1%) patients died of UTUCs and 2/161 (1.2%) patients died of surgery-related complications. Conclusion: SU provides acceptable oncological outcomes if the surgeons select candidates carefully. SU is not recommended if the patient has T3 or higher stage or comorbidity of end-stage renal disease. Concurrent bladder UC is a risk factor for worse bladder recurrence-free survival and local recurrence-free survival. Lymphovascular invasion and previous RNU for UC were related to higher local recurrence rates. After SU, periodic follow-up is mandatory because the local recurrence rate is higher than radical surgery. [ABSTRACT FROM AUTHOR]
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- 2024
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19. Sustainable sweetpotato production in the United States: Current status, challenges, and opportunities.
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George, Justin, Reddy, Gadi V. P., Wadl, Phillip A., Rutter, William, Culbreath, Julianna, Lau, Pierre W., Rashid, Tahir, Allan, Matthew C., Johaningsmeier, Suzanne D., Nelson, Amanda M., Wang, Ming Li, Gubba, Augustine, Ling, Kai‐Shu, Meng, Yan, Collins, Daniel J., Ponniah, Sathish K., and Gowda, Prasanna H.
- Abstract
Sweetpotato (Ipomoea batatas L.) is an important staple crop cultivated in over 100 countries, and the storage roots and vines provide food for humans and livestock. Sweetpotato consumption and demand for its value‐added products have increased significantly in the last two decades and have led to new cultivar development, expansion in acreage, and increased demand in the United States and its export markets. Despite the known nutritional components and other health benefits, further research is needed to characterize the genetic diversity and chemical composition related to their storage root qualities, essential in developing consumer‐preferred cultivars that offer host plant resistance against pests and pathogens. There is a critical need for research on non‐pesticidal control approaches that can provide safe, effective, economical, sustainable, and environmentally sound pest and disease management techniques, especially for socially disadvantaged small farmers in the United States. Moreover, climate change can significantly impact future production practices and yield and may directly or indirectly affect crop pests, weeds, and diseases. In this review, we discuss the current status, challenges, and future approaches associated with sweetpotato production practices; health‐promoting properties of sweetpotato cultivars; value‐added products; genetic diversity and germplasm; pest and disease management; weed and water management; pollination ecology; and other agronomic and cultural practices that may impact sustainable sweetpotato production by small‐scale, organic, and large‐scale growers. Core Ideas: Sweetpotato (Ipomoea batatas L.) is an important staple crop cultivated in over 100 countries.US sweetpotato industry faces many production challenges, including pest and diseases, as well as climate change extremes.A comprehensive review by subject matter experts on the challenges of US sweetpotato industry is not available.This review evaluates the current situation, challenges, and future approaches for improving sweetpotato production.Also, current and future impacts of climate change on global sweetpotato production and demand are discussed. [ABSTRACT FROM AUTHOR]
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- 2024
- Full Text
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20. Multiplex Profiling of Biomarker and Drug Uptake in Single Cells Using Microfluidic Flow Cytometry and Mass Spectrometry.
- Author
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Zhang, Xuan, Wei, Xing, Wu, Cheng-Xin, Men, Xue, Wang, Jiao, Bai, Jun-Jie, Sun, Xiao-Yan, Wang, Yu, Yang, Ting, Lim, Chwee Teck, Chen, Ming-Li, and Wang, Jian-Hua
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- 2024
- Full Text
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21. Electronic Structure and Transformation of Dinitrosyl Iron Complexes (DNICs) Regulated by Redox Non-Innocent Imino-Substituted Phenoxide Ligand.
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Wu, Wun-Yan, Zheng, Wei-Yuan, Chen, Wei-Ting, Tsai, Fu-Te, Tsai, Ming-Li, Pao, Chih-Wen, Chen, Jeng-Lung, and Liaw, Wen-Feng
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- 2024
- Full Text
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22. Catalytic Dehydrogenation of Formic Acid Promoted by Triphos-Co Complexes: Two Competing Pathways for H2 Production.
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Tsai, Chou-Pen, Chen, Chih-Yao, Lin, Yi-Lin, Lan, Jen-Chen, and Tsai, Ming-Li
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- 2024
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23. Determinants of the impact of ESG policy and corporate governance on employee rights.
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Chiao-Ming Li and Joe-Ming Lee
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- 2024
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24. Bioequivalence and Safety Assessment of 2 Formulations of Low‐Dose Metformin Hydrochloride under Fasting Conditions in Healthy Chinese Participants: A Randomized Phase 1 Clinical Trial
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Sun, Ming‐Li, Xu, Xin‐Wen, Liu, Chen, Tong, Yuan‐Xu, Wei, Ya‐Li, Liu, Hui‐Juan, Zhang, Wei, and Wang, Xing‐He
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The incidence of type 2 diabetes is high, and the existing metformin hydrochloride (MH) tablets of 250 mg cannot meet the demands of the Chinese drug market. This study aimed to evaluate the bioequivalence and safety of generic formulations of MH tablets (test formulation [T], 250 mg/tablet) and innovative products (reference formulation [R], 250 mg/tablet) under fasting conditions. This was an open‐label, single‐dose, 2‐period, 2‐sequence crossover, single‐center, randomized phase I clinical trial. T and R were considered bioequivalent if the adjusted geometric mean ratios (GMRs) and 90% confidence intervals of the area under the curve (AUC) and maximum concentration (Cmax) were within the range of 0.8‐1.25. Thirty‐five participants completed the trial. The T/R adjusted GMRs (95.7% for Cmax, 98.7% for AUC0→t, 98.8% for AUC0→∞) were within the acceptable bioequivalence range of 80%‐125%. No serious adverse events or suspected or unexpected serious adverse reactions occurred during this trial. The study findings confirmed that generic MH is a well‐tolerated and bioequivalent alternative to innovative products under fasting conditions in healthy Chinese participants. (www.chinadrugtrials.org.cn; registration no. CTR20190356)
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- 2024
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25. Sustainable sweetpotato production in the United States: Current status, challenges, and opportunities
- Author
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George, Justin, Reddy, Gadi V. P., Wadl, Phillip A., Rutter, William, Culbreath, Julianna, Lau, Pierre W., Rashid, Tahir, Allan, Matthew C., Johaningsmeier, Suzanne D., Nelson, Amanda M., Wang, Ming Li, Gubba, Augustine, Ling, Kai‐Shu, Meng, Yan, Collins, Daniel J., Ponniah, Sathish K., and Gowda, Prasanna H.
- Abstract
Sweetpotato (Ipomoea batatasL.) is an important staple crop cultivated in over 100 countries, and the storage roots and vines provide food for humans and livestock. Sweetpotato consumption and demand for its value‐added products have increased significantly in the last two decades and have led to new cultivar development, expansion in acreage, and increased demand in the United States and its export markets. Despite the known nutritional components and other health benefits, further research is needed to characterize the genetic diversity and chemical composition related to their storage root qualities, essential in developing consumer‐preferred cultivars that offer host plant resistance against pests and pathogens. There is a critical need for research on non‐pesticidal control approaches that can provide safe, effective, economical, sustainable, and environmentally sound pest and disease management techniques, especially for socially disadvantaged small farmers in the United States. Moreover, climate change can significantly impact future production practices and yield and may directly or indirectly affect crop pests, weeds, and diseases. In this review, we discuss the current status, challenges, and future approaches associated with sweetpotato production practices; health‐promoting properties of sweetpotato cultivars; value‐added products; genetic diversity and germplasm; pest and disease management; weed and water management; pollination ecology; and other agronomic and cultural practices that may impact sustainable sweetpotato production by small‐scale, organic, and large‐scale growers. Sweetpotato (Ipomoea batatasL.) is an important staple crop cultivated in over 100 countries.US sweetpotato industry faces many production challenges, including pest and diseases, as well as climate change extremes.A comprehensive review by subject matter experts on the challenges of US sweetpotato industry is not available.This review evaluates the current situation, challenges, and future approaches for improving sweetpotato production.Also, current and future impacts of climate change on global sweetpotato production and demand are discussed.
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- 2024
- Full Text
- View/download PDF
26. First record of plant-plant facilitative interaction from the Moscovian (Pennsylvanian, upper Carboniferous) of North China
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Wang, Ke-Yu, Huang, Xing, Yang, Wan, Wang, Jun, and Wan, Ming-Li
- Abstract
Fallen logs acting as a seedbed for trees to aid the regeneration of vegetation is a common ecological strategy in modern forests. However, the origin, occurrence, and evolution of this nurse log strategy in the geological time is unclear. Here we report a ca. 310-million-year-old permineralized cordaitalean tree trunk from the Moscovian (Pennsylvanian, upper Carboniferous) Benxi Formation in Yangquan City, Shanxi Province, North China, with evidence of probable cordaitalean rootlets growing inside the trunk. The specimen is interpreted as a nurse log for regeneration of cordaitaleans in coastal lowlands. It provides the first glimpse of plant-plant facilitative interaction between Pennsylvanian cordaitaleans in Cathaysia. We interpret that the Moscovian cordaitalean seedlings preferentially established on the fallen log owing to the ability of the rotting wood to store fresh water. The nurse log provided a stable substrate in an environment with episodic salinity and/or water table variations. In combination with previous records, it is suggested that a sophisticated terrestrial ecosystem with multiple interactions between plants and other organisms have developed on the central North China Craton no later than the Middle Pennsylvanian.
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- 2024
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27. Multiplex Profiling of Biomarker and Drug Uptake in Single Cells Using Microfluidic Flow Cytometry and Mass Spectrometry
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Zhang, Xuan, Wei, Xing, Wu, Cheng-Xin, Men, Xue, Wang, Jiao, Bai, Jun-Jie, Sun, Xiao-Yan, Wang, Yu, Yang, Ting, Lim, Chwee Teck, Chen, Ming-Li, and Wang, Jian-Hua
- Abstract
To perform multiplex profiling of single cells and eliminate the risk of potential sample loss caused by centrifugation, we developed a microfluidic flow cytometry and mass spectrometry system (μCytoMS) to evaluate the drug uptake and induced protein expression at the single cell level. It involves a microfluidic chip for the alignment and purification of single cells followed by detection with laser-induced fluorescence (LIF) and inductively coupled plasma mass spectrometry (ICP-MS). Biofunctionalized nanoprobes (BioNPs), conjugating ∼3000 6-FAM-Sgc8 aptamers on a single gold nanoparticle (AuNP) (Kd= 0.23 nM), were engineered to selectively bind with protein tyrosine kinase 7 (PTK7) on target cells. PTK7 expression induced by oxaliplatin (OXA) uptake was assayed with LIF, while ICP-MS measurement of 195Pt revealed OXA uptake of the drug in individual cells, which provided further in-depth information about the drug in relation to PTK7 expression. At an ultralow flow of ∼0.043 dyn/cm2(20 μL/min), the chip facilitates the extremely fast focusing of BioNPs labeled single cells without the need for centrifugal purification. It ensures multiplex profiling of single cells at a throughput speed of 500 cells/min as compared to 40 cells/min in previous studies. Using a machine learning algorithm to initially profile drug uptake and marker expression in tumor cell lines, μCytoMS was able to perform in situprofiling of the PTK7 response to the OXA at single-cell resolution for tests done on clinical samples from 10 breast cancer patients. It offers great potential for multiplex single-cell phenotypic analysis and clinical diagnosis.
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- 2024
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28. Electronic Structure and Transformation of Dinitrosyl Iron Complexes (DNICs) Regulated by Redox Non-Innocent Imino-Substituted Phenoxide Ligand
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Wu, Wun-Yan, Zheng, Wei-Yuan, Chen, Wei-Ting, Tsai, Fu-Te, Tsai, Ming-Li, Pao, Chih-Wen, Chen, Jeng-Lung, and Liaw, Wen-Feng
- Abstract
The coupled NO-vibrational peaks [IR νNO1775 s, 1716 vs, 1668 vs cm–1(THF)] between two adjacent [Fe(NO)2] groups implicate the electron delocalization nature of the singly O-phenoxide-bridged dinuclear dinitrosyliron complex (DNIC) [Fe(NO)2(μ-ON2Me)Fe(NO)2] (1). Electronic interplay between [Fe(NO)2] units and [ON2Me]−ligand in DNIC 1rationalizes that “hard” O-phenoxide moiety polarizes iron center(s) of [Fe(NO)2] unit(s) to enforce a “constrained” π-conjugation system acting as an electron reservoir to bestow the spin-frustrated {Fe(NO)2}9-{Fe(NO)2}9-[·ON2Me]2–electron configuration (Stotal= 1/2). This system plays a crucial role in facilitating the ligand-based redox interconversion, working in harmony to control the storage and redox-triggered transport of the [Fe(NO)2]10unit, while preserving the {Fe(NO)2}9core in DNICs {Fe(NO)2}9-[·ON2Me]2–[K-18-crown-6-ether)][(ON2Me)Fe(NO)2] (2) and {Fe(NO)2}9-[·ON2Me] [(ON2Me)Fe(NO)2][PF6] (3). Electrochemical studies suggest that the redox interconversion among [{Fe(NO)2}9-[·ON2Me]2–] DNIC 3↔ [{Fe(NO)2}9-[ON2Me]−] ↔ [{Fe(NO)2}9-[·ON2Me]] DNIC 2are kinetically feasible, corroborated by the redox shuttle between O-bridged dimerized [(μ-ONMe)2Fe2(NO)4] (4) and [K-18-crown-6-ether)][(ONMe)Fe(NO)2] (5). In parallel with this finding, the electronic structures of [{Fe(NO)2}9-{Fe(NO)2}9-[·ON2Me]2–] DNIC 1, [{Fe(NO)2}9-[·ON2Me]2–] DNIC 2, [{Fe(NO)2}9-[·ON2Me]] DNIC 3, [{Fe(NO)2}9-[ONMe]−]2DNIC 4,and [{Fe(NO)2}9-[·ONMe]2–] DNIC 5are evidenced by EPR, SQUID, and Fe K-edge pre-edge analyses, respectively.
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- 2024
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29. Catalytic Dehydrogenation of Formic Acid Promoted by Triphos-Co Complexes: Two Competing Pathways for H2Production
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Tsai, Chou-Pen, Chen, Chih-Yao, Lin, Yi-Lin, Lan, Jen-Chen, and Tsai, Ming-Li
- Abstract
In this study, we reported the synthesis and structural characterization of a triphos-CoIIcomplex [(κ3-triphos)CoII(CH3CN)2]2+(1) and a triphos-CoI-H complex [(κ2-triphos)HCoI(CO)2] (4). The facile synthetic pathways from 1to [(κ3-triphos)CoII(κ2-O2CH)]+(1′) and [(κ3-triphos)CoI(CH3CN)]+(2), respectively, as well as the interconversion between [(κ3-triphos)CoI(CO)2]+(3) and 4have been established. The activation energy barrier, associated with the dehydrogenation of a coordinated formate fragment in 1′yielding the corresponding 2accompanied by the formation of H2and CO2, was experimentally determined as 23.9 kcal/mol. With 0.01 mol % loading of 1, a maximum TON ∼ 1735 within 18 h and TOF ∼ 483 h–1for the first 3 h could be achieved. Kinetic isotope effect (KIE) values of 2.25 (kHCOOH/kDCOOH) and 1.36 (kHCOOH/kHCOOD) for the dehydrogenation of formic acid and its deuterated derivatives, respectively, implicate that the H–COOH bond cleavage is likely the rate-determining step. The catalytic mechanism proposed by density functional theory (DFT) calculations coupled with experimental 1H NMR and gas chromatography-mass spectrometry (GC-MS) analysis unveils two competing pathways for H2production; specifically, deprotonating a HCOO–H bond by a proposed Co–H intermediate Cand homolytic cleavage of the CoII–H moiety of C, presumably via a dimeric Co intermediate Dcontaining a [Co2(μ-H)2]2+core, to yield the corresponding 2and H2.
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- 2024
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30. Efficacy and safety of aldosterone synthase inhibition with and without empagliflozin for chronic kidney disease: a randomised, controlled, phase 2 trial
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Tuttle, Katherine R, Hauske, Sibylle J, Canziani, Maria Eugenia, Caramori, Maria Luiza, Cherney, David, Cronin, Lisa, Heerspink, Hiddo J L, Hugo, Christian, Nangaku, Masaomi, Rotter, Ricardo Correa, Silva, Arnold, Shah, Shimoli V, Sun, Zhichao, Urbach, Dorothea, de Zeeuw, Dick, Rossing, Peter, Tuttle, Katherine R, Hauske, Sibylle J, Canziani, Maria Eugenia, Caramori, Maria Luiza, Cherney, David, Cronin, Lisa, Heerspink, Hiddo J L, Hugo, Christian, Nangaku, Masaomi, Rotter, Ricardo Correa, Silva, Arnold, Shah, Shimoli V, Sun, Zhichao, Urbach, Dorothea, de Zeeuw, Dick, Rossing, Peter, SZETO, Cheuk Chun, Echeverri, Diego, Martin, Edouard, Yee, Ming Li, Wah, William, Wang, Ray, Chacko, Bobby, Swaminathan, Shriram, MacIsaac, Richard, Hashimura, Hikaru, Ward, Glenn, De Vusser, Katrien, Claes, Kathleen, Kuypers, Dirk, Meijers, Björn, Van Craenenbroeck, Amaryllis, Hilbrands, Robert, Debroye, Corinne, Wissing, Karl Martin, Jadoul, Michel, Demoulin, Nathalie, Treille De Grandsaigne, Serge, Beklevic, Ishak, Marcoux, Diane, Liénart, Fabienne, Daper, Claude, De Brouckere, Véronique, Heureux, Mercédès, Felicio, Joao, Felicio, Karem Mileo, Leite, Daniella, Melo, Franciane, Queiroz, Natercia, Souza, Ana Carolina, Vieira, Jocyelle, Franco, Roberto, Mendes, Adriana, Picolli, Giovana, Canani, Luis Henrique, Sartori, Carla, Valenti, Adriana, Eliaschewitz, Freddy, Bona, Renata, Franco, Denise, Ludovico Costa de Castro, Denise, Magalhaes, Vanessa, Oliveira, Marcelo, Sampaio, Célia Regina, Visconti, Guilherme, Halpern, Bruno, Nihei, Camila, Pessoa, Bruna, Seraphim, Carlos, Santos, Daniel, Brito, Claudia, Douverny, Joao, Colella, Marina, Gazeta, Cristina, Vercia, Monique, Watanabe, Renato, Temelkova, Theodora, Kjurkchiev, Dimo, Statkova, Silviya, Popov, Iliya, Radeva, Radosveta, Arabadzhiev, Lachezar, Binova, Mariya, Bosilkov, Aleksandar, Koleva-Stoicheva, Neli, Ivanov, Ivaylo, Ivanova, Zornitsa, Kotseva, Viktoria, Spasov, Petar, Tsvetkov, Ivaylo, Jolly, Shivinder, Bailey, Gordon, Ye, Zhiming, Niu, Jianying, Li, Hongmei, Wu, Qing, Liao, Bing, Hao, Chuanming, Lai, Lingyun, Xu, Yunyu, Zhang, Min, Li, Yiwen, Liu, Bo, Shao, Lina, Chen, Wei, Wu, Haishan, Pirchala, Marian, Skarpova, Iva, Hraskova, Marketa, Soukupova, Simoneta, Veberova, Lucie, Drasnar, Tomas, Falc, Matej, Racz, Blazej, Votocek, Stepan, Weissova, Danica, Syc-Krivanova, Lenka, Slezak, Dagmar, Kantola, Ilkka, Nieminen, Sakari, Anttonen, Milla, Taurio, Jyrki, Lahtela, Jorma, Tsimihodimos, Vasileios, Balafa, Olga, Dounousi, Evangelia, Sakkou, Sissy, Tentolouris, Nikolaos, Siafarikas, Christos, Siami, Evangelia, Doupis, Ioannis, Angelopoulos, Theodoros, Georgoulias, Christodoulos, Pall, Denes, Esze, Regina, Kobling, Tamas, Varadi, Zita, Zsiros, Noemi, Vass, Viktor, Balo, Timea, Csanyi, Erika, Ory, Ivan, Pall, Istvan, Patai, Valentina, Zeak, Zsuzsanna, Takacs, Istvan, Petho, Akos, Szili, Balazs, Koranyi, Laszlo, Bezzegh, Katalin, Pauer, Jozsef, Peterfai, Eva, Konyves, Laszlo, Szoke, Brigitta, Hajdu, Csaba, Kalman, Krisztina, Yadav, Raj, Saxena, Navneet, Bhattacharya, Meenakshi, Sharma, Bal, Thomas, Nihal, K, Felix Jebasingh, Kapoor, Nitin, Kurian, Mathews E., Paul, Jinson, Ramesh, Priyadharshini, Varghese, Sheeba, Shibusawa, Nobuyuki, Nishi, Hiroshi, Noritake, Nobuyasu, Oda, Takashi, Okamoto, Hideki, Kasuga, Hirotake, Hori, Hiroshi, Ito, Yukiko, Mizukoshi, Toshihiro, Ishii, Hideto, Han, Seung Hyeok, Kim, Hyung Woo, Oh, Kook-Hwan, Han, Seung Seok, Han, Sang Youb, Cha, Dae Ryong, Cha, Jin Joo, Kwon, Soon-Kil, Cho, Hyunjeong, Kim, Hye-Young, Kim, Sun Moon, Lee, Jung Pyo, Lee, Jeonghwan, Lee, Li Yuan, Chang, Meng Lee, Laang, Shian Tuck, Tan, Zhao Zhi, Ahmad Rosdi, Hajar, Mohammad Ismail, Siti Hafizah, Simatherai, Devamalar, Tay, Ju Fan, Eddie, Wong, Fook Sem, Yakob, Suryati, Abdul Sukur, Noorhafini, Anuar, Amalina, Md. Rasid, Syaliza, Mushaddik, Irma Liyana, Mustafar, Ruslinda, Abu Shamsi, Muhammad Yusuf, Fong, Voon Ken, Kamaruzaman, Lydia, Mohd, Rozita, Wan Daud, Wan Rohaslizan, Wan Hassan, Wan Hasnul Halimi, Ab Hamid, Suhaidarwani, Abdullah, Muhammad Nabil, Yusoff, Mohd Yusran, Ramanathan, G R Letchuman, Lee, Kim Yen, Wan Ismail, Wan Fadhilah, Morales Villegas, Enrique, Ramirez Baez, Rubria, Vital Lopez, Jorge, Arias Delgadillo, Cristhian, Herrera Marmolejo, Marisol, Parra Perez, Rosa, Alpizar Salazar, Melchor, Flores Montealegre, Ana, Galvan Magaña, Jose, Gutierrez Tlapale, Minerva, Reyes Munguia, Daniela, Witczak, Bartlomiej, Gøransson, Lasse, Strand Thorsen, Inga, Caringal, Clodoaido, Villardo, Mario, Toledo, Ronaldo, Dijamco, Emerlinda Fausto, De Asis, Norman Cornelio, Kuizon, Angelica, Catindig, Elizabeth Ann, Perez, Ronald, Aquitania, Grace, Pableo, Jimrie David, Sanchez, Jay Karlou, Czernecka, Ewa, Cegiel, Aleksandra, Knychas, Dorota, Ochnio, Malgorzata, Kuligowska-Jakubowska, Monika, Cesarz, Marek, Kowalewska-Celejewska, Milena, Masajtis-Zagajewska, Anna, Jankowski, Lukasz, Ojrzanowski, Marcin, Olszewska-Jander, Magdalena, Skokowska, Ewa, Giermakowska-Samek, Malgorzata, Luchowska, Elzbieta, Patkowska, Renata, Sekulska, Marzenna, Marczuk-Krynicka, Dorota, Marciniak, Andrzej, Barwijuk, Michal, Myslicki, Marcin, Siek, Michal, Wronska, Danuta, Tomsia-Goncerz, Jadwiga, Wronski, Krzysztof, Junik, Roman, Dzialak, Szymon, Kurlapska, Ewelina, Malecha, Wieslaw, Suwala, Szymon, Branco, Patrícia, Birne, Rita, Raposo, João, Ferreira, Marta, Alexandrino, Henrique, Alves, Helena, Correia, Sara, Oliveira, Maria João, Ramalho, Diogo, Tavares, Patricia, Coetzee, Kathleen, Blignaut, Sue, Viljoen, Winifred, Potgieter, Elsje, Malherbe, Elmien, Ortiz Arduán, Alberto, Goma Garcés, Elena, Pérez, María, Santamaría, Rafael, López López, Isabel, Pendón de Mier, Victoria, Rodelo Haad, Cristian, Marques, María, Domènech, Esther, Portoles, Josep Maria, Soler, María José, Agraz, Irene, Azancot, María Antonieta, Bermejo, Sheila, Bolufer, Mónica, López, Marina, Ramos, Natalia, Toapanta, Néstor, Cigarrán Guldris, Secundino, Primo, Juan Carlos, Pérez, Luis Enrique, Rebollido Fernández, María, Holmer, Helene, Bruchfeld, Annette, Rofors, Justus, Tengmark, Bengt-Olov, Wuerzner, Gregoire, Leanizbarrutia, Garazi, Ozturk, Savas, Guler, Nurana, Safak, Seda, Lee, Keung, Campbell, Stephen, Siddiqui, Imran, Abbasi, Nadia, Tahir, Faiza, Azizad, Masoud, Jackson, Timothy, Everhart, Brian, Oliver, Michael, Rust, William, Sniezek, Matthew, Arif, Ahmed, Syed, Mohammed, Bhasin, Nitin, Bien, Michael, Gallego, Claudio, Jamal, Aamir, Moghadam, Mojtaba, Rizvi, Abid, Rizvi, Amna, Rizvi, Syed, Wong, Christopher, Lucas, Kathryn, Buery, Andrea, Chang, Ku-Lang, Presswood, Claire, Smith, Justin, Doshi, Ankur, Parikh, Manish, Wallace, Jeannine, Krishna, Arvind, Daugherty, Heidi, Fearday, Aaron, Keller, Christopher, Meng, Jerry, Nielsen, Alexandra, Rovner, Sergio, Almeida, Javier, Marranzini, Benito, Selby, Lisa, Yablon, Zachary, Jean-Louis, Daphne, Kotzker, Wayne, Perez, Chabely, Richards, Marc, Rosario, Reinaldo, Marcus, Roy, Okechukwu, Chike, Ross, Dennis, Gromala, Rachel, Reed, Matthew, Weber, Lisa, Nazeer, Imran, Kumar, Prashant, Mir, Muhammad, Shea, Heidi, Hart, Amanda, Wiebel, Jaime, Kooienga, Laura, Newsome, Britt, Suyumova, Irina, Alvarez, German, Bireddy, Venkata, Lansang, Maria, Mandry, Jose, Freire, Maria, Herrera Albornoz, Oscarina, Desai, Anant, Gandhi, Dayan, Rajan, Sibu, Raymond, Louis, Posada, Jorge, Garcia-Mayol, Luis, Gutierrez-Alsina, Rodolfo, Fernandez, Juan, Bruce, Kendaling, Cuellar, Juan, Ranz y Alvarez, Maria, Bartolacci, Ines, Pautasso, Mauro, Stoppa, Daniela, Riella, Miguel, Barbosa, Maria, Harcsa, Eleonora, Gulati, Yuvraj, Savalia, Denish, Khetan, Prakash, Sinha, Dhananjay, R, Niranjan, K, Srinivas, Pazos, Fabiola, Gacutan-Liwag, Aretha, Duszynska, Malgorzata, Antkowiak-Piatyszek, Karolina, Konieczny, Grzegorz, Sidorowicz-Bialynicka, Anna, Ciesiolkiewicz-Wojcik, Agnieszka, Dwojak, Marek, Szymkowiak, Katarzyna, Gorczyca-Siudak, Daria, Janik-Palazzolo, Marzena, Siudak, Lukasz, Opiela, Jaroslaw, Iwanow, Dariusz, Solkiewicz, Monika, Sipinska-Surzynska, Malgorzata, Olszanecka - Glinianowicz, Magdalena, Rozmilowska, Izabela, Trokis, Julian, Prozesky, Hans, Burgess, Lesley, Cyster, Henry, Jordaan, Jurie, Mohamed, Hawa, Naude, Christina, Sitsila, Thembie, Mehta, Arvind, Mocherla, Bharat, Lee, Sungchun, Boren, Kenneth, Rudolph, Lance, Benjamin, Sabrina, Sugimoto, Danny, Hammoud, Jamal, Bakleh, Muhammad, Hashish, Yaseen, Da Costa, Jonathan, Gold, Marina, Majul, Claudio, Buscema, Juan, Gatto, Maria, Lombardi, Facundo, Paez, Olga, Puleio, Pablo, Alvarisqueta, Andrés, Pajon, Vanessa, Suarez, Gabriel, Hernandez Gauna, Adrian, Pereyra, Alejandro, Reig, Moira, Gelersztein, Elizabeth, Campestri, Gina, Gonzalez Santos, Maria, Sambresqui, Julieta, Catalano, Gustavo, Igarzabal, Cecilia, Vallejos, Augusto, Escobari, Claudio, Marchetto, Rocio, Chahin, Mariano, Aguilera, Andrea, Comes, Ana, Rodriguez Segade, Silvia, Baccaro, Claudia, Larrieu Lacoste, María Verónica, Saurral, Ruben, Cristino, Alberto, Dran, Dario, Koretzky, Martin, Ponti, Juan, Porto, Alejandro, Tenaglia, Yasmin, Maldonado, Natacha, Bertollo, Natalia, Van Perdeck, Verónica, Lopau, Kai, Wanner, Christoph, Berfelo, Florieke, Contzen, Christel, Arbi, Abdulwahab, Lee-Barkey, Young Hee, Maciejewska, Aleksandra, Arelin, Katrin, Haller, Hermann, Kaufeld, Jessica, Schmidt-Ott, Kai, Heinrichs, Sven, Krüger, Thilo, Gebauer, Chris, Paliege, Alexander, Henkel, Elena, Axthelm, Christoph, Derwahl, Karl-Michael, Trevisan, Roberto, Bellante, Rosalia, Borrella, Nicolò, Corsi, Anna, Gesualdo, Loreto, Ardillo, Teodora, Ficarella, Maria, Fikry, Sameh, Mazza, Giuseppe, Poirier, Lysane, Bajaj, Harpreet, Hatziagelaki, Erifili, Katopodis, Sokratis, Katsoudas, Spiros, Yamaura, Shuichi, Shikano, Tsutomu, Tosaki, Takahiro, Miho, Otoya, Tachibana, Naoki, Yumita, Wataru, Kado, Hiroshi, Villarreal Martinez, Jesus, Soto Miranda, Ernesto, Gonzalez Rodriguez, David, Panelo, Araceli, Santos, Telma, Birne, Rita, Branco, Patrícia, Martins, Ana, Mateus, Catarina, Teixeira e Costa, Fernando, Barreto, Sara, Silva Costa, Joana, Ferrer, Francisco, Silva, Joana, Awad, Ahmed, Khaleel, Shatha, Lustig, Ryan, Maharjan, Gajendra, Moya, Jaynier, Johnsingh, Amit, Acosta, Idalia, Newman, George, Buckle, Anita, and Hendon, Kendra
- Abstract
Excess aldosterone accelerates chronic kidney disease progression. This phase 2 clinical trial assessed BI 690517, an aldosterone synthase inhibitor, for efficacy, safety, and dose selection.
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- 2024
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31. G protein-coupled receptor kinase 2 as a novel therapeutic target for gland fibrosis of Sjögren’s syndrome
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Fang, Ru-hong, Zhou, Zheng-wei, Chu, Rui, Guan, Qiu-yun, He, Feng, Ge, Ming-li, Guo, Pai-pai, Wu, Hua-xun, Yao, Ling-li, Wei, Wei, Ma, Yang, and Wang, Qing-tong
- Abstract
Sjogren’s syndrome (SS) is a chronic, progressive autoimmune disorder characterized by gland fibrosis. We previously found a close correlation between gland fibrosis and the expression of G protein-coupled receptor kinase 2 (GRK2). In this study we explored the pathological and therapeutic significance of GRK2 in SS. Submandibular gland (SMG) antigen-induced SS mouse model was established in WT and GRK2+/–mice. We showed that the expression levels of GRK2 were significantly up-regulated in glandular tissue and positively correlated with fibrotic morphology in SS patients and mice. Hemizygous knockout of GRK2 significantly inhibited the gland fibrosis. In mouse salivary gland epithelial cells (SGECs), we demonstrated that GRK2 interacted with Smad2/3 to positively regulate the activation of TGF-β-Smad signaling with a TGF-β-GRK2 positive feedback loop contributing to gland fibrosis. Hemizygous knockout of GRK2 attenuated TGF-β-induced collagen I production in SGECs in vitro and hindered gland fibrosis in murine SS though preventing Smad2/3 nuclear translocation. Around 28 days post immunization with SMG antigen, WT SS mice were treated with a specific GRK2 inhibitor paroxetine (Par, 5 mg·kg−1·d−1, i.g. for 19 days). We found that Par administration significantly attenuated gland fibrosis and alleviated the progression of SS in mice. We conclude that genetic knockdown or pharmacological inhibition of GRK2 significantly attenuates gland fibrosis and alleviates the progression of SS. GRK2 binds to Smad2/3 and positively regulates the activation of TGF-β-Smad signaling. A TGF-β-GRK2 positive feedback loop contributes to gland fibrosis. Our research points out that GRK2 could be a promising therapeutic target for treating SS.
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- 2024
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32. Further Study on Goal Programming Models.
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Yu-Lan Wang and Ming-Li Chen
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GOAL programming ,FUZZY numbers ,RESEARCH personnel ,CALCULUS ,CENTROID - Abstract
In this study, we investigate various goal programming models and highlight their problematic outcomes, offering our revised versions. While previous publications relied on numerical examples to determine the optimal alternative, we provide theoretical explanations for these examples to enhance researchers' understanding of goal programming models. Additionally, we employ a fast integration approach to solve a challenging calculus problem concerning the centroid of trapezoidal fuzzy numbers. Our findings aim to assist researchers in comprehending intricate theoretical concepts and facilitate the application of these results in their own research endeavors. [ABSTRACT FROM AUTHOR]
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- 2023
33. Clinical Analysis of Intranasal Dexmedetomidine Combined With Midazolam in Pediatric Cranial Magnetic Resonance Examinations.
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Li, Si-Jie, Shen, Kai-Feng, He, Li, Zhang, Yu-Ping, Ming, Li, and Wu, Zhi-Feng
- Abstract
To observe the efficacy and safety of intranasal dexmedetomidine combined with midazolam in cranial magnetic resonance imaging of children. A prospective, observational, single-arm, one-center study. A total of 474 children were scheduled for cranial 3.0 T MRI at the first time. All patients were initially given 3 mcg/kg dexmedetomidine combined with 0.15 mg/kg midazolam. The one-time success rate, vital signs before and after treatment, onset time, recovery time, and incidence of adverse reactions were recorded. The one-time success rate was 78.1%. There were significant differences in respiration, heart rate, and blood oxygen saturation before and after treatment (P <.001). The onset time was 10 (8-15) minutes. The average recovery time was 2.58 ± 1.10 hours. Only 1.27% (6 cases) of adverse reactions were observed, including bradycardia (3 cases, 0.6%), tachycardia (1 case, 0.2%), and startle (2 cases, 0.4%). No special treatment was needed. The success of the examination was significantly correlated with age (OR 1.320, 95% CI 1.019-1.710, P =.035) and onset time (OR 0.959, 95% CI 0.921-0.998, P =.038). Dexmedetomidine 3 mcg/kg combined with midazolam 0.15 mg/kg intranasally has a good sedative effect in pediatric cranial magnetic resonance examinations, little impact on breathing and circulation, and few adverse reactions. Age and onset time are related factors affecting the one-time success rate. [ABSTRACT FROM AUTHOR]
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- 2023
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34. A Bibliometric Analysis of Outcome-based Education Practices in the Education Domain.
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Ming Li and Rohayati, M. I.
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OUTCOME-based education ,BIBLIOMETRICS ,MEDICAL teaching personnel ,CITATION indexes ,ENGINEERING education ,TEACHER educators - Abstract
Purpose: This study attempts to provide a comprehensive knowledge mapping and an in-depth analysis of Outcome-based education (OBE) practices to identify the research hotspots and development trends in this field which emerged between 1985 and 2023. Method: This study conducted a descriptive bibliometric analysis of 685 articles retrieved from the Web of Science Core Collection (WoSCC) databases relevant to Outcome-based education. Microsoft Excel and VoSviewer were used to characterize the contributions of countries, institutions, authors, and collaborative networks. The research hot spots and development trends were analyzed by Citespace and Vosiviewer. Findings: The results highlighted that the USA, England, and China were the three primary contributors to the largest number of publications in this field. But China needs to prioritize the quality of publications. The University of Dundee, the University of Toronto, and the University of California System were the three most productive institutions with the highest number of publications. Harden R. M. stood out as one of the most prolific authors in this field. Medical Teacher and Medical Education were the two most productive journals. The teaching process, framework, quality assurance, impact, and engineering education were the highly discussed issues in recent years. Implications for Research and Practice: The identification of prolific scholars and highly cited articles serves as references for scholars and educators new to OBE, assisting them in enhancing their reading efficiency and tracking authoritative scholars. This study also suggests that the research institutions and authors should strengthen cross-regional and international cooperation to enhance the implementation of OBE in education. [ABSTRACT FROM AUTHOR]
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- 2023
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35. Pattern of Brain Parenchymal Damage Related to Cerebral Small Vessel Disease in Carriers of Rare NOTCH3 Variants.
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Zi-Yue Liu, Fei-Fei Zhai, Jing-Yi Liu, Yi-Jun Zhou, Mei-Jun Shu, Xiao-Hong Huang, Fei Han, Ming-Li Li, Li-Xin Zhou, Jun Ni, Ming Yao, Shu-Yang Zhang, Li-Ying Cui, Zheng-Yu Jin, and Yi-Cheng Zhu
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- 2023
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36. Interaction of Cellular Uptake of Nanosilver and Metallothionein Stress Expression Elucidated by 2D Single-Cell Analyses Based on LIF and ICP-MS.
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Wang, Jiao, Wei, Xing, Wu, Cheng-Xin, Zhang, Xuan, Wei, Yu-Jia, Liu, Jin-Hui, Wang, Yu, Chen, Ming-Li, and Wang, Jian-Hua
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- 2023
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37. The safety and efficacy between remimazolam and propofol in intravenous anesthesia of endoscopy operation: a systematic review and meta-analysis.
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Mei-ji Zhao, Hai-feng Hu, Xin-lei Li, Xiao-ming Li, Da-chuan Wang, and Ming-jie Kuang
- Abstract
Background: Propofol is the most widely used intravenous anesthetic in endoscopic surgery, but is associated with several adverse reactions. Public research has shown that remimazolam, a safe general anesthetic, is increasingly being used as a substitute for propofol in clinical operations. Our meta-analysis aimed to analyze whether the adverse reaction rate of remimazolam in endoscopic surgery is acceptable and whether the surgical success rate is not lower than that of propofol. Aim: This meta-analysis examined the adverse events and efficacy of remimazolam vs. propofol during endoscopic surgery. Method: MEDLINE, Embase, ClinicalTrials.gov, and Google Scholar were comprehensively searched. Seven studies comparing remimazolam and propofol were included in our meta-analysis. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and Cochrane manual were used to assess the quality of the results published in all included studies to ensure that our meta-analysis results are reliable and worthwhile. Results: Compared to propofol, the use of remimazolam reduced postoperative injection pain [relative risk (RR) = 0.06, 95% confidence interval (CI): 0.03-0.12, P<0.00001], postoperative hypotension (RR=0.45, 95% CI: 0.28-0.73, P=0.001), and postoperative respiratory depression (RR=0.20, 95% CI: 0.08-0.47, P=0.0002); however, it also slightly reduced the success rate of the operation [risk difference (RD)= - 0.02, 95% CI: - 0.04 to - 0.01, P=0.0007]. There were no significant differences in the occurrence of bradycardia symptoms after the operation (RD= - 0.01, 95% CI: - 0.03 to 0.01, P= 0.35), recovery time after the operation [standardized mean difference (SMD)=0.68, 95% CI: - 0.43 to 1.80, P =0.23] or discharge time (SMD =0.17, 95% CI: -0.58 to 0.23, P =0.41). We also performed a subgroup analysis of each corresponding outcome. Conclusion: Our analysis showed that remimazolam may be a safer shock option than propofol for endoscopic surgery. However, further research is required to determine their utility. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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38. Prognostic nutritional index with postoperative complications and 2-year mortality in hip fracture patients: an observational cohort study.
- Author
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Yilin Wang, Yu Jiang, Yan Luo, Xisheng Lin, Mi Song, Jia Li, Jingxin Zhao, Ming Li, Yuheng Jiang, Pengbin Yin, Peifu Tang, Houchen Lyu, and Licheng Zhang
- Abstract
Background: The prognostic nutritional index (PNI) has been proposed as a useful prognostic tool in multiple populations. However, its prognostic value has not been fully evaluated in the hip fracture population. We aimed to assess the relationship between PNI and postoperative complications as well as 2-year all-cause mortality in the hip fracture population. Materials and Methods: We included patients aged 45 or older who underwent surgery for hip fracture between 2000 and 2022. The baseline serum albumin and total lymphocyte count were used to calculate PNI with the following formula: 10 × serum albumin level (g/dl)+0.005 × total lymphocyte count (per mm3). Patients were classified into low, medium, and high categories based on tertiles of PNI (=43.23, 43.23-47.35, and >47.35, respectively). Logistic regression and Cox proportional hazards models were used to calculate the odds ratio (OR) for postoperative compilations and the hazard ratio (HR) for mortality, adjusting for potential confounders. Results: Of 3351 hip patients, 236 (7.04%) developed postoperative complications, and 305 (9.10%) died during the 2-year follow-up. Compared to the low-category patients, the medium-category and high-category patients showed lower odds of postoperative complications (ORs 0.69, 95% CI 0.48-0.98; and 0.61, 95% CI 0.40-0.93, respectively), and lower hazards of 2-year mortality (HRs 0.66, 95% CI 0.49-0.88; and 0.61, 95% CI 0.42-0.88, respectively). These associations were robust across a series of analyses, including subgroup analyses and dose-response sensitivity analyses. Conclusion: PNI is an independent predictor of postoperative complications and 2-year all-causemortality in hip fracture patients. PNI can be used to identify patients who may be at high risk of a poor prognosis. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
39. Synthesis and performance evaluation of terpolymer high temperature retarder for oil well cement.
- Author
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Yongjin Yu, Xiaoying Wu, Jintang Guo, Xiujian Xia, Ping Zhou, Huiting Liu, and Ming Li
- Subjects
OIL well cementing ,HIGH temperatures ,MALEIC acid ,MOLECULAR structure ,ENERGY consumption - Abstract
With the increase of energy demand in the world, the exploration of deep and ultra-deep wells is increasing, which also puts forward higher requirements for cementing quality. Among them, retarder is a key material to ensure the safety of cementing operation. In view of the poor temperature resistance of conventional retarder, this paper introduces temperature-resistant and saltresistant groups, optimizes the molecular structure design, and uses 2-acrylamido-2-methylpropanesulfonic acid (AMPS), maleic acid (MA) and polycyclic cycloolefin lactam (NX) as monomers to synthesize high temperature resistant retarder (AMN) by free radical aqueous solution polymerization and used as high temperature retarder in oil well cement. The results show that polymer retarder AMN has certain molecular weight and excellent temperature resistance. The performance evaluation results show that AMN has a good retarding effect at 140 C and has no adverse effect on the development of mechanical strength of cement paste. AMN can solve the problem that conventional retarder is easy to fail at high temperature, and it has a good application prospect in deep and ultra-deep well cementing. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
40. Single Cell Phenotypic Analysis for Cancer Stem Cell Identification by Dual-Isotope ICP-QMS.
- Author
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Liu, Meijun, Wei, Xing, Wu, Chengxin, Liu, Jinhui, Wei, Yujia, Wang, Xuesheng, Chen, Ming-Li, Yang, Ting, and Wang, Jian-Hua
- Published
- 2023
- Full Text
- View/download PDF
41. Two-Dimensional Multi-parameter Cytometry Platform for Single-Cell Analysis.
- Author
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Wu, Chengxin, Men, Xue, Liu, Meijun, Wei, Yujia, Wei, Xing, Yu, Yong-Liang, Xu, Zhang-Run, Chen, Ming-Li, and Wang, Jian-Hua
- Published
- 2023
- Full Text
- View/download PDF
42. A study on the election factors of an ACM Fellow based on the co-authorship relations.
- Author
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Hailing Zhou, Xiaole Li, Jin Shi, Ming Li, and Lingyun Situ
- Abstract
Prior research on successful groups of scientists has predominantly focused on recipients of top international awards, while investigations into the Association for Computing Machinery (ACM) Fellow award - an esteemed academic honor in the field of Computing Machinery - have been relatively scarce. This article seeks to address this gap by examining the relationship between the success of ACM Fellows and their co-authorship characteristics with previous Fellows. Using a sample of ACM Advanced Member Grades from 2015 to 2020 in four sub-domains, relevant indicators were selected to measure the cooperative relationship between candidates and previous Fellows. The relationship between successful elected ACM Fellows and their co-authorship with previous Fellows was analyzed using correlation analysis and binary logistic regression methods. The results indicate that a cooperative relationship with previous Fellows is indeed beneficial for the candidate's selection as a potential ACM Fellow. Several significant factors impact the probability of becoming fellow, including (a) the contribution ratio of previous Fellows to Fellow candidates, (b) the number of cooperative previous Fellows towards the Fellow candidate, (c) the degree of cooperation with previous Fellows, and (d) the propensity to cooperate with “growing together type” Fellows. Additionally, the impact of the nature of the collaboration on the campaign varies across different sub-fields. The findings not only suggest a potential closing on the Fellowship circle, but also serve as a safeguard against biases and opportunistic tendencies that may undermine the recognition of deserving Fellows. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
43. Nomogram Models for Distinguishing Intraductal Carcinoma of the Prostate From Prostatic Acinar Adenocarcinoma Based on Multiparametric Magnetic Resonance Imaging Carcinoma: 2023 Expert Consensus-Based Practical Recommendations of the Korean Liver...
- Author
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Ling Yang, Xue-Ming Li, Meng-Ni Zhang, Jin Yao, and Bin Song
- Published
- 2023
- Full Text
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44. A Microscopic Prediction Model for Traffic Noise in Adjacent Regions to Arterial Roads.
- Author
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Ming LI and Jizhou LIU
- Published
- 2023
- Full Text
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45. Sublobar resection versus lobectomy for stage IA non-small-cell lung cancer ≤ 2 cm: a systematic review and patient-level meta-analysis
- Author
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Fong, Khi Yung, Chan, Yiong Huak, Chia, Cynthia Ming Li, Agasthian, Thiruganam, and Lee, Pyng
- Abstract
Despite lobectomy being the standard of care for early-stage non-small-cell lung cancer (NSCLC), sublobar resection (segmentectomy or wedge resection) has recently been suggested to achieve similar outcomes. An electronic literature search was conducted to retrieve randomized controlled trials (RCTs) or propensity score-matched studies (PSMs) comparing lobectomy to sublobar resection in stage IA NSCLC ≤ 2 cm in size, with provision of Kaplan–Meier curves for overall survival (OS) and disease-free survival (DFS). A graphical reconstructive algorithm was used to obtain OS and DFS of individual patients, which was then pooled under random-effects individual patient data meta-analysis using Cox models to determine hazard ratios (HRs). Sensitivity analyses for OS and DFS were also performed, restricting to results from RCTs only. Seven studies (2528 patients) were retrieved. There were no significant differences in OS (shared-frailty HR = 0.92, 95% CI = 0.77–1.11, p= 0.378) or DFS (shared-frailty HR = 1.06, 95% CI = 0.90–1.24, p= 0.476) between lobectomy and sublobar resection. This comparison remained non-significant even when restricted to RCTs only. Pooled Kaplan–Meier curves of OS appeared to diverge over time, in favor of sublobar resection. This was confirmed on analysis of restricted mean survival time curves. This patient-level meta-analysis of high-quality studies demonstrates that sublobar resection is equivalent to lobectomy in patients with small stage IA NSCLC. Sublobar resection offers greater down-the-road benefits in patients who experience recurrence or a second primary tumor since the lung-sparing index surgery allows patients to receive further treatment safely. This heralds sublobar resection as the new standard of care in carefully selected early-stage patients.
- Published
- 2023
- Full Text
- View/download PDF
46. Bionic Flexible Texture Design Based on Bio-Fouling Suppression Effect for Protection of Marine Structures
- Author
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Yi, Peng, Wu, Yu-peng, Cai, Bao-ping, Tian, Xing-hui, Mostaghimi, Javad, Yang, Xiao-shuang, and Lyu, Ming-li
- Abstract
Marine equipments such as marine risers and oil pipelines operate in complex underwater environments and are usually attached by animals, plants and microorganisms. The attachment of marine fouling organisms will accelerate the corrosion damage of offshore structure and greatly reduce the service life. Studies have shown that non-smooth bionic surfaces with specific microstructures can inhibit fouling formation. Based on the idea of bionics, this paper proposes a new type of underwater flexible fretting texture, which is a composite material prepared by mixing graphene and silicone rubber, and modified by pulsed laser to construct a hexagonal bionic surface texture. Under the impact of specific water flow, the flexible texture can produce an angular displacement around 8° and a linear displacement in the amplitude range of 165 µm, and the inhibition rate of fouling biological diatoms up to 97.5%, which can effectively avoid the occurrence of marine biological fouling. The results provide a new idea for the surface protection of marine structures, which is of great significance for the development of marine industry.
- Published
- 2023
- Full Text
- View/download PDF
47. Three-Dimensional Maneuver Control of Multiagent Systems With Constrained Input
- Author
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Chen, Yu-Wen, Chiang, Ming-Li, and Fu, Li-Chen
- Abstract
In this article, we propose a new 3-D maneuver controller for a class of nonlinear multiagent systems (MASs) with nonholonomic constraint and saturated control. The system is designed under a distributed communication topology and the controller is more flexible and efficient for general formation maneuver tasks. The saturation design generates control inputs within pregiven bounds, which makes the system more applicable in practice. Moreover, based on the nonholonomic model, the proposed control also considers the heading angles of the agents. Thus, the maneuver controller can achieve a more natural tracking movement where the heading of the formation will align to the direction of the reference trajectory during the tracking motion. Several simulation examples are given to validate our results and demonstrate the competence for various maneuver tasks of MASs.
- Published
- 2023
- Full Text
- View/download PDF
48. Block Compressed Sensing Image Reconstruction via Untrained Network Priors.
- Author
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Lan Li, Xiao-Long Qiu, Ming-Li Jing, and Sha-Sha Pu
- Subjects
COMPRESSED sensing ,IMAGE reconstruction ,SENSES - Abstract
In this paper, we consider image reconstruction methods for block compressed sensing (BCS). We model images to lie in the range of an untrained network for every subblock and combine the projected gradient descent algorithm to improve the performance. This proposed method is named BCS_PGDNET. Meanwhile, sufficient condition is provided for algorithmic convergence. We compare with the following algorithm: OMP, COSAMP, IRLS, BCS_SPL_DDWT, BCS_ FOCUSS, BCS_SPL_DCT. Experimental simulations show that BCS_PGDNET method have better recovery performance than main-stream CS methods and BCS methods with relative higher PSNR and SSIM, and tradeoffs between block size and the improved reconstruction performance are discussed. This is generation of compressed sensing (CS) with untrained network priors. [ABSTRACT FROM AUTHOR]
- Published
- 2023
49. A Novel Self-Learning Filters for Automatic Modulation Classification Based on Deep Residual Shrinking Networks.
- Author
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Ming Li, Xiaolin Zhang, Rongchen Sun, Zengmao Chen, and Chenghao Liu
- Subjects
AUTOMATIC classification ,SIGNAL classification ,TELECOMMUNICATION systems - Abstract
Automatic modulation classification is a critical algorithm for non-cooperative communication systems. This paper addresses the challenging problem of closed-set and openset signal modulation classification in complex channels. We propose a novel approach that incorporates a self-learning filter and center-loss in Deep Residual Shrinking Networks (DRSN) for closed-set modulation classification, and the Opendistance method for open-set modulation classification. Our approach achieves better performance than existing methods in both closed-set and open-set recognition. In closed-set recognition, the self-learning filter and center-loss combination improves recognition performance, with a maximum accuracy of over 92.18%. In open-set recognition, the use of a self-learning filter and center-loss provide an effective feature vector for open-set recognition, and the Opendistance method outperforms SoftMax and OpenMax in F1 scores and mean average accuracy under high openness. Overall, our proposed approach demonstrates promising results for automatic modulation classification, providing better performance in non-cooperative communication systems. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
50. Impact of the Early Stage of the COVID-19 Pandemic on Smoking Cessation in Beijing.
- Author
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Yao, WANG and Xing Ming, LI
- Subjects
SMOKING cessation ,COVID-19 pandemic - Published
- 2023
- Full Text
- View/download PDF
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