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AbstractWith the improvement of people’s living standards and the awakening of environmental rights awareness, pollution and mass environmental incidents have become the focus of public attention. Using grounded theory analysis in qualitative research and multivariate statistical technology in quantitative research, taking residents and public officials of Shijiazhuang, Tangshan and Heng Shui as the research objects, Study 1 has defined the concept of the political cost of environmental problems (PCEP) and has constructed the PCEP scale by using the methods of interview and questionnaire survey, which provided sufficient theoretical explanation and empirical support for the research on the political cost of environmental problems. Study 2 has explored the relationship between PCEP and the environment-friendly behaviors, verified the applicability of the scale, and found the institutional PCEP, the organizational PCEP, the social PCEP, and the mass basic PCEP all have a positive impact on environment-friendly behaviors.

Photodynamic therapy (PDT) is quickly developing as a hopeful cancer treatment. However, hypoxic tumors, poor targeting, and photosensitizers (PS) aggregation limited the efficiency of PDT. Here, we report a hyaluronic acid (HA)-modified CeO2-nanoparticle-decorated metal–organic framework (PCN-224@CeO2-HA) to enhance PDT and achieve targeted treatment. CeO2catalyzes H2O2to produce O2to solve hypoxia problems. HA could target the CD44 receptor, which is highly expressed on the tumor cell membranes. The growth of tumor cells 4T1 and MCF-7 was controlled distinctly after being incubated with PCN-224@CeO2-HA under laser irradiation, while the survival ability of normal cell LO2 was nearly unchanged. Importantly, PCN-224@CeO2-HA could be effectively aggregated within the tumor area after 12 h of injection, and the tumor growth was remarkably inhibited under laser irradiation. PCN-224@CeO2-HA presented good biocompatibility and an excellent antitumor effect, providing a new strategy to produce O2in situfor enhanced PDT.