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2. Comparison of Beneficial Metabolic Effects of Liraglutide and Semaglutide in Male C57BL/6J Mice

Author

Liu, Dinghui, Gu, Jianqiu, Shao, Weijuan, Pang, Juan, Qian, Xiaoxian, and Jin, Tianru

Abstract

Semaglutide and liraglutide are glucagon-like peptide-1 (GLP-1)–based diabetes drugs. Semaglutide possesses a longer half-life. Utilizing relatively lower doses, we compared the beneficial metabolic effects of these 2 drugs in mice fed a high-fat diet (HFD), aiming to deepen our mechanistic understanding on their energy homeostatic functions.

Published
2022
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